Stable metal organic frameworks are prized for their ability to capture carbon dioxide or harvest atmospheric water, but U-M researchers have developed a use for unstable metal organic frameworks: as a system for drug delivery.
Ninety percent of drugs in development don’t dissolve well or at all in the body, according to a 2012 study. Metal organic frameworks, or MOFs, are rigid, porous structures composed of metal linked by organic ligands. While researching unstable MOFs, U-M chemist Adam Matzger realized they may work as a delivery system for these kinds of drugs.
