22.5mg bisoprolol daily for constant AF

[Kstandsteve]

Hi, I have constant AF and have been on 20mg bisoprolol and 10 mg digoxin for several years. I have however recently been taken off digoxin which has left my heart rate higher than the acceptable rate. I have as a result had my bisoprolol disease increased to 22.5mg daily and was wandering is this considered a high dose of bisoprolol and how have other people found their level of exhaustion and tiredness whilst taking this amount. I am 55 year old female.

[Wodney1966]

Wow that’s a lot 22.5 bisoporol

[Kstandsteve in reply to Wodney1966]

My thoughts too hope that someone may be able to put my mind at rest as it was doc prescribed and not cardiologist

[Wodney1966]

I’m on 12.5 and my cardiologist didn’t really want me to go on it it was my ep who put me on

[BobD Volunteer]

I think most people would be comatose on that amount.

[Luludean]

That seems a lot of Bisoprolol!!

I can't take it nor, flecanaide nor verapamamil. but I am fine on -25 micrograms of Digoxin.I have persistent AF. We all have different cocktails.

[CaroleF]

I no longer take Bisoprolol, but even on 2.5mg a day I felt washed out. 22.5mg seems a very high dose to me. I don't recall anyone here mentioning taking a dose of more than 10mg daily. If it were me, I'd be querying this dose. with whoever prescribed it.

[jedimasterlincoln]

22? Blimey! I have been on 10mg most of this year, as well as in years previous. All in conjunction with other drugs like Amiodrone, Dronedrone and Flecanide. 10mg took a lot of getting used to, and in the weeks leading up to my recent ablation I was even on an extra 2.5 at night, but the A&E reg had to run it past the Cardiologist on call first to make sure it was OK.

I can't possibly imagine how I'd feel on double the dose, the general consensus on putting the dose up to 12.5 a day was that was the absolutle limit!

[jedimasterlincoln in reply to jedimasterlincoln]

On a quick browse, I see the max dose recommended is generally 20mg per day. It could be you were punted the extra 2.5 to try and help keep a lid on your symptoms, as I was when I was on 12.5.

[Hidden]

I take 2.5 and it tires me may be worth querying it. I also take Flecainide twice a day

[Hidden]

Crikey! Do you really mean 22.5mg??

I could barely move on 10mg. When I've been in A&E 10mg was the max given. Are you in the UK?

[cassie46]

I take 5 mg and have had it upped to 7.5mg on a few occasions. 7.5mg gave me brain fog as I call it and generally not with it so had to reduce back to 5 mg. 22.5mg and I think I would be away with the faires. I have always been told 10 mg is about the max.

[P0rtnahapp1e]

10 mg is the maximum for those suffering from HF, but the max for others is 20 mg. The only reason I know this is that there was a heated debate between my consultant and a more junior doctor which culminated in them both going off to get reference books and reading them at the bedside. 😀

I am on 12.5 mg which is actually on the high side since I have HF and AF, although I was reduced to 10mg after my latest cardioversion, but increased after 3 days when it failed.

[julesp]

I take 10 mg and have been on 20mg for a while at one point.

[Mazza23]

i am on 10 mg a day and was told that ws the max in an emergancy they will give me another 2.5 but no more i would be in a coma on that amount

[Hidden]

Gosh! When I was first diagnosed I was put on the lowest dose of 1.25 and after three days of tiredness, was told to stop taking it immediately- goodness knows how slow my heart was beating then as I hadn't yet got a Kardia but I am not surprised that you are feeling tired on a dose that is 18 times more! Of course, we are all different and I am a slim woman but even so! Just saw that this was an old post so hope you have it sorted now and are doing well!

[Overseventy]

I am on bisoprolol 3.75 and complained of feeling tired all the time and my doctor upped it to 5 now feel worse. If bisoprolol makes you feel tired why did he increase the dose ?

[JOY2THEWORLD49]

HiYes very high dose

Try with specialist CCB Diltriazem. A CCB is a Calcium Channel blocker

I tried and reduced but CONTROL of AF and BP same day.

I have been taking

120mg Diltriazem for 4.5 months now

and 2.5 Bisoprolol at night.

they needed separation

BP 123/72. 93 hpm avge at rest day

48 hpm avge night

cheers JOY