Electrochemotherapy

[aprail]

Hi has anyone had this ?

[cesanon]

What exactly is it?

[aprail in reply to cesanon]

Had it in Germany last week ,went to clinic for Nanoknife but they recommended this treatment.Had not heard of it but needed to do something, like you had not heard of it .

[cesces in reply to aprail]

Please describe the nature of the treatment. Not a good sign if you don't understand what the treatment was and how it worked. If you think about it.

[aprail in reply to cesces]

I did think about it and as I am not medically trained I don't understand the exact process.I came here to find if anyone else had the treatment.Clays711 has kindly put up an article on it.

[Clays711]

I found this with a quick search:

pubs.rsna.org/doi/full/10.1...

[aprail in reply to Clays711]

Thanks.

[dadzone43]

What is it?

[Kuanyin]

There is a company on the NASDAQ called Novocure (I once held stock in this company). This is from their home page:

Tumor Treating Fields (TTFields) are electric fields that exert physical forces to kill cancer cells via a variety of mechanisms. TTFields do not significantly affect healthy cells because they have different properties (including division rate, morphology, and electrical properties) than cancer cells. The multiple, distinct mechanisms of TTFields therapy work together to selectively target and kill cancer cells. Due to its multimechanistic actions, TTFields therapy can be added to cancer treatment modalities in approved indications and demonstrates enhanced effects across solid tumor types when used with chemotherapy, radiotherapy, immune checkpoint inhibition, or PARP inhibition in preclinical models. TTFields therapy provides clinical versatility that has the potential to help address treatment challenges across a range of solid tumors. To learn more about Tumor Treating Fields therapy and its multifaceted effect on cancer cells, visit tumortreatingfields.com.

[aprail in reply to Kuanyin]

Thanks

[Justfor_]

Don't want to discourage you, but I only remember a unique user here dealing with salvage treatments after IRE recurrence. Did you have the version in which additional chemo or something is injected along with the electrodes? If memory serves, said person had not.

PS: After a quick search, GP24 wrote here (you can ask him directly he is very knowledgeable) :

healthunlocked.com/advanced...

"Spyder, I had IRE done six years ago and know other patients who had it done. So I did share my experience. My treatment was no failure but I do not think it was that much better that I should recommend it to other patients. Part of the reason is that it costs a lot of money and is not covered by your health insurance. I got recurrences in both seminal vesicles and the prostate bed plus urinary retention caused by a damaged urethra.

That is why I recommended to look into radiation, if you consult seven surgeons you should consult more than one RO. If you want a cytoreductive therapy you can just ask the RO to omit the areas close to the bladder and the rectum. Tell him you want no cure, just the mothership removed.

IRE does damage organs, e.g. the prostate 😀, but you may be able to keep a distance to other organs when placing the needles. This treatment does not ablate tumor cells selectively, it will destroy any cell with the electric current between the needles."

[aprail in reply to Justfor_]

Ye I had chemo in it.

[j-o-h-n]

Could be a bit shocking I suppose...

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 03/23/2023 9:15 PM EST