nicotinamide phosphoribosyltransferase

[fco1969]

Hi. This new news seems interesting

https: //thelancet. com / jour nals / ebiom / article / PIIS2352-3964 (20) 30435-7 / fulltext El

[fco1969]

thelancet.com/journals/ebio...

[j-o-h-n]

nicotinamide phosphoribosyltransferase jr. = Hey that's my Greek cousin's name.

Good Luck, Good Health and Good Humor.

j-o-h-n Tuesday 10/13/2020 6:26 PM DST

[Kaliber in reply to j-o-h-n]

I know that family , think I dated his sister nicknamed Westina ! Wrinkledstillskin Elaine Supercalifragilisticexpialidocious. She was wonderful.

Just say’in

[j-o-h-n in reply to Kaliber]

She ended up marrying nicotinamide phosphoribosyltransferase jr. and kept her maiden name as her middle name.

BTW If I had another son I would have named him Nickname.......(or Noneofyourfxxkingbusiness)....

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 10/14/2020 2:46 PM DST

[Kaliber in reply to j-o-h-n]

Or you could name him ....OhchitIfrukedupandshuddaworeprotectiondamnit

I like your nickname better tho ... it’s easier to spell.

Just say’in 🤪🔨👀🌵

[j-o-h-n in reply to Kaliber]

But your's gets right to the hearton of the matter....

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 10/14/2020 4:40 PM DST

[Kaliber in reply to j-o-h-n]

😂😂😂😂

[Graham49]

There's some interesting stuff about this on Wikipedia.

Here are some snippets.

"The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity."

"Although the original cytokine function of PBEF has not been confirmed to date, others have since reported or suggested a cytokine-like function for this protein.[18] In particular, Nampt/PBEF was recently re-identified as a "new visceral fat-derived hormone" named visfatin.[19]

"Because cancer cells utilize increased glycolysis, and because NAD enhances glycolysis, Nampt is often amplified in cancer cells.[23][24] APO866 is an experimental drug that inhibits this enzyme.[25] It is being tested for treatment of advanced melanoma, cutaneous T-cell lymphoma (CTL), and refractory or relapsed B-chronic lymphocytic leukemia."

"Anti-aging biomedical company Calico has licensed the experimental P7C3 analogs involved in enhancing NAMPT activity.[26] P7C3 compounds have been shown in a number of publications to be beneficial in animal models for age-related neurodegeneration.[27][28]"