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clinical trial RBN-2397-19-001
Any thoughts on RBN 2397 an oral PARP7 inhibitor? Husband is out of options so considering this trial. Thank you for your input.
Any thoughts on RBN 2397 an oral PARP7 inhibitor? Husband is out of options so considering this trial. Thank you for your input.
Cynthgob
in
Advanced Prostate Cancer
1 year ago
BAT in Argentina
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934967/ Results A total of 21 asymptomatic patients with mCRPC were included. There was a median of two lines before BAT, with nine patients (42.8%) receiving three or more lines, and 13 patients (61.9%) receiving chemotherapy previously. Previous lines
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9934967/ Results A total of 21 asymptomatic patients with mCRPC were included. There was a median of two lines before BAT, with nine patients (42.8%) receiving three or more lines, and 13 patients (61.9%) receiving chemotherapy previously. Previous lines
pjoshea13
in
Fight Prostate Cancer
1 year ago
A shared story of SCA3
Bill Moore & his daughter Jessica Oberlin, two members of NAF, recently shared their stories of living with SCA3 as part of a feature for the Critical Path to Therapeutics for the Ataxias (CPTA). The CPTA aims to optimize clinical trials for inherited Ataxias. Impact stories like theirs can help researchers
Bill Moore & his daughter Jessica Oberlin, two members of NAF, recently shared their stories of living with SCA3 as part of a feature for the Critical Path to Therapeutics for the Ataxias (CPTA). The CPTA aims to optimize clinical trials for inherited Ataxias. Impact stories like theirs can help researchers
wobblybee
in
Ataxia UK
1 year ago
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Supporting Children Suffering from Narcolepsy
This week, we hear from FACES of Narcolepsy founder Erin Carey's - this is a truly inspiring story of love, support and fearless devotion. -------- I created FACES of Narcolepsy in 2017 when I joined forces with four other moms from across the U.S. to fill a need in the pediatric narcolepsy community
This week, we hear from FACES of Narcolepsy founder Erin Carey's - this is a truly inspiring story of love, support and fearless devotion. -------- I created FACES of Narcolepsy in 2017 when I joined forces with four other moms from across the U.S. to fill a need in the pediatric narcolepsy community
SaskiaHU
HealthUnlocked
in
HealthUnlocked Blog
1 year ago
Tube removal and FET
Hi guys, Had a HSG done yesterday and it confirmed I have a hydrosalpinx. Devastated as we were prepping for FET next month. Had a laparoscopy in Feb which didn't highlight a hydrosalpinx so it must be fairly new. Planning to go for surgery to remove my tube with the hydrosalpinx. Just wondering
Hi guys, Had a HSG done yesterday and it confirmed I have a hydrosalpinx. Devastated as we were prepping for FET next month. Had a laparoscopy in Feb which didn't highlight a hydrosalpinx so it must be fairly new. Planning to go for surgery to remove my tube with the hydrosalpinx. Just wondering
RaintoRainbows
in
Fertility Network UK
2 years ago
KEYNOTE-B96 Clinical trial
Hello, ladies. Is anyone on the KEYNOTE-B96? It's weekly Taxol plus Avastin plus Pembrolizumab/Placebo for platinum-resistant recurrent ovarian cancer.
Hello, ladies. Is anyone on the KEYNOTE-B96? It's weekly Taxol plus Avastin plus Pembrolizumab/Placebo for platinum-resistant recurrent ovarian cancer.
Vilinew
in
My Ovacome
1 year ago
ORION -4
Wondering has anybody out there being offered the chance to do the clinical trial for a new drug called Inclisiran. It may be the answer to lower LDL cholesterol. I have been offered the chance and took up the offer anything to help.?
Wondering has anybody out there being offered the chance to do the clinical trial for a new drug called Inclisiran. It may be the answer to lower LDL cholesterol. I have been offered the chance and took up the offer anything to help.?
Sizzlerman
in
British Heart Foundation
1 year ago
How to truly forgive?
I struggle with
clinical
, treatment resistant
depression
and pure OCD to name a few. I'm also still recovering from a minor concussion that I believe makes my symptoms worse. I wanted to know how to truly forgive? I need to learn to TRULY LET THINGS GO AND FORGIVE.
I struggle with
clinical
, treatment resistant
depression
and pure OCD to name a few. I'm also still recovering from a minor concussion that I believe makes my symptoms worse. I wanted to know how to truly forgive? I need to learn to TRULY LET THINGS GO AND FORGIVE.
HealingInProcess
in
Anxiety and Depression Support
17 days ago
Emotional rollercoaster
I joined the forum only a few weeks ago, at a time I was very severely struggling with major depression. I had little hope, but I was near my all-time low and desperately needed to try something. Anything. Since I joined, I have received countless kind words, helpful advice and reading suggestions,
I joined the forum only a few weeks ago, at a time I was very severely struggling with major depression. I had little hope, but I was near my all-time low and desperately needed to try something. Anything. Since I joined, I have received countless kind words, helpful advice and reading suggestions,
Sylvain-
in
Anxiety and Depression Support
2 years ago
Interesting
Clinical Review of ropeginterferon alfa-2b Suggests Amended Dosing Schedule May Support Improved Clinical Outcomes in Polycythemia Vera Review of studies published in Frontiers in Oncology highlights dosing considerations that may help more patients achieve earlier complete hematological response
Clinical Review of ropeginterferon alfa-2b Suggests Amended Dosing Schedule May Support Improved Clinical Outcomes in Polycythemia Vera Review of studies published in Frontiers in Oncology highlights dosing considerations that may help more patients achieve earlier complete hematological response
wateron
in
MPN Voice
1 year ago
Better measures of disease severity needed in lupus, study says
Experts urge change in ways of assessing clinical trial outcomes by Marisa Wexler, MS | February 16, 2023
New measures are needed to assess disease severity in lupus in clinical trials, a study highlights.
One important goal in developing such measures is to include patient-reported outcomes
Experts urge change in ways of assessing clinical trial outcomes by Marisa Wexler, MS | February 16, 2023
New measures are needed to assess disease severity in lupus in clinical trials, a study highlights.
One important goal in developing such measures is to include patient-reported outcomes
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
1 year ago
Are there any clinical trials currently using mRNA technologies to fight PC?
Still in the fight 13 years out using SBRT for tumors and Lupron and Xtandi for system wide control currently. Just wondering if there are any trials out there using mRNA technologies to harness the human immune system in the fight. Seems like a logical next step.
Still in the fight 13 years out using SBRT for tumors and Lupron and Xtandi for system wide control currently. Just wondering if there are any trials out there using mRNA technologies to harness the human immune system in the fight. Seems like a logical next step.
Rocketman1960
in
Advanced Prostate Cancer
1 year ago
Coping with heat
I need your advice my friends. We live in the north of England and rarely get a heatwave but this summer we had 2 and my HWP, who is in his 29th year of diagnosis, really suffered. I looked on HU and saw this can be a problen in PD. I told him what I had read and dealt with it with fans and cold packs
I need your advice my friends. We live in the north of England and rarely get a heatwave but this summer we had 2 and my HWP, who is in his 29th year of diagnosis, really suffered. I looked on HU and saw this can be a problen in PD. I told him what I had read and dealt with it with fans and cold packs
JeanieBeanie
in
Cure Parkinson's
2 years ago
What do you wish people knew about pancreatitis? | Rare Disease Day
This #RareDiseaseDay, bring awareness to chronic pancreatitis and inspire others to help find a cure by showing off your purple stripes! Leading up to #RareDiseaseDay, we'll be posting questions on our social media accounts to help others learn about the disease, starting with the question: What do you
This #RareDiseaseDay, bring awareness to chronic pancreatitis and inspire others to help find a cure by showing off your purple stripes! Leading up to #RareDiseaseDay, we'll be posting questions on our social media accounts to help others learn about the disease, starting with the question: What do you
Skye_MC
Administrator
in
Chronic Pancreatitis Support
1 year ago
Professor Kristien Boelaert appointed President-Elect of the British Thyroid Association
It might be of interest that the current President, Professor Simon Pearce (Newcastle), will be replaced sometime soon. [i]
Professor Kristien Boelaert appointed President-Elect of the British Thyroid Association
[/i] [i][/i] [i]A member of the BTA for more than 20 years, Professor Boelaert
It might be of interest that the current President, Professor Simon Pearce (Newcastle), will be replaced sometime soon. [i]
Professor Kristien Boelaert appointed President-Elect of the British Thyroid Association
[/i] [i][/i] [i]A member of the BTA for more than 20 years, Professor Boelaert
helvella
Thyroid UK
in
Thyroid UK
1 year ago
The Worst State of Depression.
I've had
clinical
depression
and anxiety from 5 years. I am taking medications with good compliance. I also got my medications changed twice. But from 2 weeks, my depression and anxiety has crippled me. It has grasped me tightly. I am literally numbed to the core. Unable to do a thing.
I've had
clinical
depression
and anxiety from 5 years. I am taking medications with good compliance. I also got my medications changed twice. But from 2 weeks, my depression and anxiety has crippled me. It has grasped me tightly. I am literally numbed to the core. Unable to do a thing.
Docmalik71
in
Anxiety and Depression Support
2 years ago
FILSPARI (sparsentan)
Hi All - Sorry if this has already been posted, but below is a copy and paste of an email I received from NephCure. Dear NephCure friends, Today marks an incredibly promising day for the rare kidney disease (RKD) community: the FDA has announced that the drug FILSPARI (sparsentan) has been granted
Hi All - Sorry if this has already been posted, but below is a copy and paste of an email I received from NephCure. Dear NephCure friends, Today marks an incredibly promising day for the rare kidney disease (RKD) community: the FDA has announced that the drug FILSPARI (sparsentan) has been granted
Boulder98
in
Kidney Disease
1 year ago
depression, anxiety, panic
depression, anxiety, panic and fear of becoming that bi polar high guy that spends all my money. It never ends. Like there is no hope. Considering giving guardianship to my son because I can’t be trusted with my finances. There just seems to be no “in between “ place ever.
depression, anxiety, panic and fear of becoming that bi polar high guy that spends all my money. It never ends. Like there is no hope. Considering giving guardianship to my son because I can’t be trusted with my finances. There just seems to be no “in between “ place ever.
Redbeard53
in
Anxiety and Depression Support
2 years ago
Beat Prostate Cancer
I was reading some clinical trial data the other day. To summarize, the treatment being tested did not pass muster. It worked marginally better than standard of care but not well enough to change standard of care. The irony of the study concerned overall survival and progression free survival. The control
I was reading some clinical trial data the other day. To summarize, the treatment being tested did not pass muster. It worked marginally better than standard of care but not well enough to change standard of care. The irony of the study concerned overall survival and progression free survival. The control
Todd1963
in
Advanced Prostate Cancer
1 year ago
📚 Research 101: Placebos
A placebo is a sugar pill that does not cause harm or good. In many trials testing an investigational medication, a proportion of the people recruited will receive a placebo without knowing if they are receiving the investigational medication or the placebo. [u]
When you may not get a placebo
[
A placebo is a sugar pill that does not cause harm or good. In many trials testing an investigational medication, a proportion of the people recruited will receive a placebo without knowing if they are receiving the investigational medication or the placebo. [u]
When you may not get a placebo
[
AnnaHU
HealthUnlocked
in
Research Opportunities
1 year ago
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