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Zytiga
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Why has my PSA declined dramatically since Xtandi failed?
(Before starting Xtandi, I had 3 years on
Zytiga
). I’ve had 2 PSA tests since quitting Xtandi. Results of the 1st lab: my PSA dropped from 46 to 33. 2nd lab last week: PSA down to 17. Also, I’ve added back 14 of the 55 pounds I lost in the last 5 months.
(Before starting Xtandi, I had 3 years on
Zytiga
). I’ve had 2 PSA tests since quitting Xtandi. Results of the 1st lab: my PSA dropped from 46 to 33. 2nd lab last week: PSA down to 17. Also, I’ve added back 14 of the 55 pounds I lost in the last 5 months.
BillDoc
in
Advanced Prostate Cancer
4 years ago
My PSA has been .02 for the last year but my testosterone is climbing. Why?
I have been on Lupron,,
Zytiga
and Pred for the last two years. I was thinking of a drug vacation because of my low PSA but the rising testosterone is worrying me. Any thoughts gentlemen?
I have been on Lupron,,
Zytiga
and Pred for the last two years. I was thinking of a drug vacation because of my low PSA but the rising testosterone is worrying me. Any thoughts gentlemen?
Fitzbruce1
in
Advanced Prostate Cancer
4 years ago
One year and change... and change... and change
That the pain is the
Zytiga
working. That the pain is anything other than the cancer eating him from the inside out. I'm drinking too much. That's probably obvious from this post. I no longer know how to help him, or help myself. Love to you all. Thank you for letting me dump it all here.
That the pain is the
Zytiga
working. That the pain is anything other than the cancer eating him from the inside out. I'm drinking too much. That's probably obvious from this post. I no longer know how to help him, or help myself. Love to you all. Thank you for letting me dump it all here.
CantChoose
in
Advanced Prostate Cancer
4 years ago
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Castrate resistant
He had a bone scan last week and it showed some metastasis to the sternum the right shoulder and the right hip so they’re putting him on
Zytiga
!! I can’t even tell you how petrified I am what is going to happen.
He had a bone scan last week and it showed some metastasis to the sternum the right shoulder and the right hip so they’re putting him on
Zytiga
!! I can’t even tell you how petrified I am what is going to happen.
Fight11
in
Advanced Prostate Cancer
4 years ago
Need advice - radiation to inguinal lymph nodes and rib
Started Eligard +
Zytiga
and had during March 2020 RapidArc 20x with 3Gy per fraction to prostate + 13x with 3Gy per fraction to bone mets in pelvic area (controversial thing).
Started Eligard +
Zytiga
and had during March 2020 RapidArc 20x with 3Gy per fraction to prostate + 13x with 3Gy per fraction to bone mets in pelvic area (controversial thing).
45yrsDenmark
in
Advanced Prostate Cancer
4 years ago
5 years Stage 4
Just joined I have been taking 1000mg
Zytiga
with prednisone 5mg 2x day for about 2 years. I also get Lupron shots every 6 months. Radiation about 5 years ago. Also had Immunotherapy about 1 year ago small drop in PSA & testosterone.
Just joined I have been taking 1000mg
Zytiga
with prednisone 5mg 2x day for about 2 years. I also get Lupron shots every 6 months. Radiation about 5 years ago. Also had Immunotherapy about 1 year ago small drop in PSA & testosterone.
S42019
in
Advanced Prostate Cancer
4 years ago
Previous photon radiation to pelvic & lumbar=>proton beam radiation?
He is also taking
Zytiga
(6.5 weeks now), which I think is not working. Would it be prudent for him to have proton beam radiation since it's ill advised to have photon radiation to the same area more than once?
He is also taking
Zytiga
(6.5 weeks now), which I think is not working. Would it be prudent for him to have proton beam radiation since it's ill advised to have photon radiation to the same area more than once?
AerospaceElectrical
in
Advanced Prostate Cancer
4 years ago
Xtandi after Zytiga
Quick question... anyone have success on Xtandi after failure of
Zytiga
? (8 months)
Quick question... anyone have success on Xtandi after failure of
Zytiga
? (8 months)
Faith1111
in
Advanced Prostate Cancer
4 years ago
ADT vacation nearing an end
Just an update...recap: been on an ADT vacation since early December 2019 when PSA had been at 0.000 for the previous 8 months after having been on Lupron &
Zytiga
for 16 months (since August 18).
Just an update...recap: been on an ADT vacation since early December 2019 when PSA had been at 0.000 for the previous 8 months after having been on Lupron &
Zytiga
for 16 months (since August 18).
Ron53
in
Advanced Prostate Cancer
4 years ago
My father has extreme pain in his legs
He is currently taking
zytiga
/prednisone and Lupron shots. I feel like this extreme leg pain started with those meds. He is taking OxyContin 10 mg 2x a day and oxycodine 5mg in between no more than 3 a day he is allowed. He said the only thing that helps is Aleeve but dr told him to stop taking it.
He is currently taking
zytiga
/prednisone and Lupron shots. I feel like this extreme leg pain started with those meds. He is taking OxyContin 10 mg 2x a day and oxycodine 5mg in between no more than 3 a day he is allowed. He said the only thing that helps is Aleeve but dr told him to stop taking it.
Weezer513
in
Advanced Prostate Cancer
4 years ago
The Difficult Question most all of us will face.
Zolodex, Lupron, Casodex, Erleada, Xtandi,
Zytiga
w\predisone, now Docetaxel. We discussed the options again and how they could buy time or not. 1) Continue with Chemo but use Cabazitaxel instead: Cabazitaxel he said was more toxic and may be less tolerated than Docetaxel.
Zolodex, Lupron, Casodex, Erleada, Xtandi,
Zytiga
w\predisone, now Docetaxel. We discussed the options again and how they could buy time or not. 1) Continue with Chemo but use Cabazitaxel instead: Cabazitaxel he said was more toxic and may be less tolerated than Docetaxel.
dpowellnt
in
Advanced Prostate Cancer
4 years ago
Zytiga Has Stopped. What's next
PSA started at 250+ in November. Got down to 7 in April. Since then has risen to 19 in July. Had a bone and CT scan. Unfortunately it was mixed news. There is evidence of progression in my bone disease. However, spots on my lung and Kidney are gone. My Onc wants me to start on Xgeva in two weeks
PSA started at 250+ in November. Got down to 7 in April. Since then has risen to 19 in July. Had a bone and CT scan. Unfortunately it was mixed news. There is evidence of progression in my bone disease. However, spots on my lung and Kidney are gone. My Onc wants me to start on Xgeva in two weeks
Newyork6264
in
Advanced Prostate Cancer
4 years ago
Spontaneous twitchy wrist
Onc says
zytiga
not the cause (I have been on it for 21 months), COC say their drugs (metformin etc) very unlikely to be the cause (been on them for a year), and I am on many of the Jane McLelland recommended supps: berberine, curcamin, low dose aspirin, loratadine, HCA, quercetin, ursolic acid, resveratrol
Onc says
zytiga
not the cause (I have been on it for 21 months), COC say their drugs (metformin etc) very unlikely to be the cause (been on them for a year), and I am on many of the Jane McLelland recommended supps: berberine, curcamin, low dose aspirin, loratadine, HCA, quercetin, ursolic acid, resveratrol
rpol
in
Advanced Prostate Cancer
4 years ago
Hi...my husband stopped taking zytiga/pred. due to a long story...been 3 months now...he's at .01 psa though is stage 4
any words of wisdom?? He's 75 , lost muscle and bone mass I'm sure...almost 2 yrs since diagnosis ...still on lupron...scan shows mets throughout skeleton but have decreased...he now has an almost recognizable personality since coming off...sigh...I do worry though...he won't tell the MO and not sure
any words of wisdom?? He's 75 , lost muscle and bone mass I'm sure...almost 2 yrs since diagnosis ...still on lupron...scan shows mets throughout skeleton but have decreased...he now has an almost recognizable personality since coming off...sigh...I do worry though...he won't tell the MO and not sure
Sunnyby11
in
Advanced Prostate Cancer
4 years ago
To state the obvious: early use of Zytiga or Xtandi extends survival in APC
. •
Zytiga
and Xtandi have been proven to add years of life in the mHSPC setting in some men, and months in the mCRPC setting, so avoiding those medicines [u]will reduce expected survival[/u]. • A recent study at Johns Hopkins showed that the t-SCNC subtype is less virulent than de novo SCNC https://
. •
Zytiga
and Xtandi have been proven to add years of life in the mHSPC setting in some men, and months in the mCRPC setting, so avoiding those medicines [u]will reduce expected survival[/u]. • A recent study at Johns Hopkins showed that the t-SCNC subtype is less virulent than de novo SCNC https://
Tall_Allen
in
Advanced Prostate Cancer
4 years ago
Docetaxel vs Zytiga
This lab work was ordered by my Urologist, who upon seeing it recommended continuing on Lupron and adding
Zytiga
. He also recommends laser ablation of my prostate to deal with frequent urinations which recently have become slightly painful and sometimes bloody.
This lab work was ordered by my Urologist, who upon seeing it recommended continuing on Lupron and adding
Zytiga
. He also recommends laser ablation of my prostate to deal with frequent urinations which recently have become slightly painful and sometimes bloody.
Frigataflyer
in
Advanced Prostate Cancer
4 years ago
Xtandi side effects
He is 82 has been on most treatments like Provange,
Zytiga
, on currently and since this battle started Lupron and Xgeva but now he’s on xtandi. Numbers are great.
He is 82 has been on most treatments like Provange,
Zytiga
, on currently and since this battle started Lupron and Xgeva but now he’s on xtandi. Numbers are great.
Olivia007
in
Advanced Prostate Cancer
4 years ago
Reformulating Zytiga -
I have read several posts about those who are able to halve the dosage of
Zytiga
with a meal/med plan - so I thought this article was interesting.
I have read several posts about those who are able to halve the dosage of
Zytiga
with a meal/med plan - so I thought this article was interesting.
mintlatte
in
Advanced Prostate Cancer
4 years ago
Update
Had radiation, Lupron and
Zytiga
prescribed for two years. My last Lupron injection was this past March. I will finish with
Zytiga
next month (July). My MO said, then we wait and see. Any comments will be appreciated. Thanks
Had radiation, Lupron and
Zytiga
prescribed for two years. My last Lupron injection was this past March. I will finish with
Zytiga
next month (July). My MO said, then we wait and see. Any comments will be appreciated. Thanks
Jif1
in
Men's Health Forum
4 years ago
Two nodules in Lungs
His treatment these years has been
Zytiga
, Prednisone and Lupron every 3 months. Today we have been told that PSA remains undetectable and there is no progress in bone metastasis. However, two small nodules (less than 5 mm) have been detected in his lung.
His treatment these years has been
Zytiga
, Prednisone and Lupron every 3 months. Today we have been told that PSA remains undetectable and there is no progress in bone metastasis. However, two small nodules (less than 5 mm) have been detected in his lung.
Noel91
in
Advanced Prostate Cancer
4 years ago
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