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Transurethral resection of the prostate (TURP)
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One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems?
One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems? If you have had surgery, Salvage Radiation, ADT, SRBT and then stopped ADT with a continuing rise in you PSA when did you start to have pain or physical problems?
One questions doctors never seem to be able to answer is at what PSA level do you start to experience pain or physical problems? If you have had surgery, Salvage Radiation, ADT, SRBT and then stopped ADT with a continuing rise in you PSA when did you start to have pain or physical problems?
Exrunner
in
Advanced Prostate Cancer
3 months ago
Enzalutamide vs Lupron Survival
This shows the main results of the EMBARK trial, comparing Metatasis Free Survival and PSA Recurrence Free Survival for three groups: Enzalutamide only, Lupron only, or combined Enzalutamide + Lupron. The best survivals were for the combination of Enzalutamide + Lupron. Enzalutamide is a 2nd generation
This shows the main results of the EMBARK trial, comparing Metatasis Free Survival and PSA Recurrence Free Survival for three groups: Enzalutamide only, Lupron only, or combined Enzalutamide + Lupron. The best survivals were for the combination of Enzalutamide + Lupron. Enzalutamide is a 2nd generation
janebob99
in
Prostate Cancer Network
3 months ago
Maybe because of "careful" patient selection, but still great: PSA Undetectable in First Patient Cu-67 SAR-bisPSMA
Positive results for mCRPC, very positive. Sorry if I have already posted this (my mind is not so sharp lately...was it ever??). "The first patient with prostate cancer dosed with 2 cycles of 8GBq of 67Cu-SAR-bisPSMA has reached undetectable prostate specific antigen (PSA) levels using PET" https:/
Positive results for mCRPC, very positive. Sorry if I have already posted this (my mind is not so sharp lately...was it ever??). "The first patient with prostate cancer dosed with 2 cycles of 8GBq of 67Cu-SAR-bisPSMA has reached undetectable prostate specific antigen (PSA) levels using PET" https:/
Maxone73
in
Advanced Prostate Cancer
5 months ago
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În panica again
Hello, everybody! Wishing you a happy and bright spring! I need you expertise and oppinions again. My father is taking Xtandy for over 1.2 years and lately psa started to grow, I attached his psa situation since january 2022. I read about Xtandy here all the time. It never worked so good for him, I
Hello, everybody! Wishing you a happy and bright spring! I need you expertise and oppinions again. My father is taking Xtandy for over 1.2 years and lately psa started to grow, I attached his psa situation since january 2022. I read about Xtandy here all the time. It never worked so good for him, I
tuta1960
in
Advanced Prostate Cancer
3 months ago
Pluvicto Question
Just had third Pluvicto in fusion and Spect scan today and got results. Not sure what this means. If the findings are similar compared to the last scan why does this indicate"technically successful" therapy. Also PSA went down just slightly after infusion number two but went up a little from PSA after
Just had third Pluvicto in fusion and Spect scan today and got results. Not sure what this means. If the findings are similar compared to the last scan why does this indicate"technically successful" therapy. Also PSA went down just slightly after infusion number two but went up a little from PSA after
spencoid2
in
Advanced Prostate Cancer
3 months ago
life Insurance
I wanted to get opinions regarding my life insurance 800K which will be expiring in a couple of months. I have the option to roll it over to a universal policy but it’s going to cost me 2K a month. I’m still Homone sensitive. And been on ADT and Nubeqa (daroludimide) for the last couple of years. Had
I wanted to get opinions regarding my life insurance 800K which will be expiring in a couple of months. I have the option to roll it over to a universal policy but it’s going to cost me 2K a month. I’m still Homone sensitive. And been on ADT and Nubeqa (daroludimide) for the last couple of years. Had
JDKotter
in
Advanced Prostate Cancer
3 months ago
PSA now undetectable with 2 of 35 radiation treatments left.
PSA now undetectable with 2 of 35 radiation treatments left to complete. I will start Abiraterone next week, in addition to the Lupron I’m currently on. I’m celebrating today’s victory and wanted to share here. Of course, many days have been consumed with worry over the unknown. This group has been
PSA now undetectable with 2 of 35 radiation treatments left to complete. I will start Abiraterone next week, in addition to the Lupron I’m currently on. I’m celebrating today’s victory and wanted to share here. Of course, many days have been consumed with worry over the unknown. This group has been
Stereo1
in
Advanced Prostate Cancer
3 months ago
ISO a third MO opinion for my dad
Hi all! My dad was diagnosed with pca in 2021, prostate removal that summer. After radical - was told no treatment necessary and lo and behold January the following year psa went from .04 to 1.2 in 3 months. Put on adt and zytiga (not sure of spelling), scans show pelvic bed spots and 1 on s1, radiation
Hi all! My dad was diagnosed with pca in 2021, prostate removal that summer. After radical - was told no treatment necessary and lo and behold January the following year psa went from .04 to 1.2 in 3 months. Put on adt and zytiga (not sure of spelling), scans show pelvic bed spots and 1 on s1, radiation
Dsmejkal88
in
Advanced Prostate Cancer
3 months ago
PSA vs Testosterone Nadir for CRPC and Non-CRPC
This plot from Safriadi (2022) compares the mean values of PSA nadir versus Testosterone Nadir comparing Non-Castrate Resistant PC (Non-CRPC) to Castrate-Resistant PC (CRPC) men. For Non-CRPC men, the range of T-nadir was 2.5-49 ng/dL (mean = 21) and range for PSA nadir was 0.02-9 ng/mL (mean=2). For
This plot from Safriadi (2022) compares the mean values of PSA nadir versus Testosterone Nadir comparing Non-Castrate Resistant PC (Non-CRPC) to Castrate-Resistant PC (CRPC) men. For Non-CRPC men, the range of T-nadir was 2.5-49 ng/dL (mean = 21) and range for PSA nadir was 0.02-9 ng/mL (mean=2). For
janebob99
in
Advanced Prostate Cancer
3 months ago
PSA Score Doubling / Lab Error?
Hey folks I was diagnosed back in 2017 with 3+3, later upgraded to 3+4, but with less then 5% of G4. Epstein reviewed and said he would go against Johns Hopkins policy to automatically treat ANY amount of G4 and stick with AS, at least in my situation. Before and since my diagnosis, my PSA score has
Hey folks I was diagnosed back in 2017 with 3+3, later upgraded to 3+4, but with less then 5% of G4. Epstein reviewed and said he would go against Johns Hopkins policy to automatically treat ANY amount of G4 and stick with AS, at least in my situation. Before and since my diagnosis, my PSA score has
PTvsPC
in
Prostate Cancer Network
3 months ago
Docxtel triple therapy?
Thank you for sharing your thoughts. My dad--81, advanced metastatic castrate resistant Diagnosed at 79 with stage 4 met 8 bones, including skull, no Gleason, never even saw a urologist. Diagnosed in ER and sent straight to the oncologist and palliative care doctor. PSA initially at 137 Lupron
Thank you for sharing your thoughts. My dad--81, advanced metastatic castrate resistant Diagnosed at 79 with stage 4 met 8 bones, including skull, no Gleason, never even saw a urologist. Diagnosed in ER and sent straight to the oncologist and palliative care doctor. PSA initially at 137 Lupron
lgutman
in
Advanced Prostate Cancer
3 months ago
Adding second line hormonal therapy?
Hello everyone. My father's treatment from diagnosis consisted of ADT (Zoladex, 3-month injections as of now) and 6 courses of Docetaxel chemotherapy. PSA nadir was 0.89 after 7 months of treatment but after that the last 3 PSA tests show increase (PSA 2.310 on 24 Oct. 2023, PSA 6.81 on 24 Nov. 2023
Hello everyone. My father's treatment from diagnosis consisted of ADT (Zoladex, 3-month injections as of now) and 6 courses of Docetaxel chemotherapy. PSA nadir was 0.89 after 7 months of treatment but after that the last 3 PSA tests show increase (PSA 2.310 on 24 Oct. 2023, PSA 6.81 on 24 Nov. 2023
gio2x
in
Advanced Prostate Cancer
5 months ago
PSA reduction by Estrogen Patch (revised)
Here's a revised plot of PSA reduction due to castration from Estrogen Patch therapy. The previous version had the wrong time scale. That has been corrected in this version. The total time is 3 months, after which the PSA and testosterone both flattened out versus time. I've also added the reference
Here's a revised plot of PSA reduction due to castration from Estrogen Patch therapy. The previous version had the wrong time scale. That has been corrected in this version. The total time is 3 months, after which the PSA and testosterone both flattened out versus time. I've also added the reference
janebob99
in
Prostate Cancer Network
3 months ago
Dumb Question about rising PSA after initial RT.
If you still have a prostate after RT treatment 7 years ago ( NO ADT), could a slowly rising PSA just be 'natural' as you age? Have always been curious, as when initial biopsy was ordered, the doctor said, "if you were a few months older (70), your PSA level would not have prompted further investigation
If you still have a prostate after RT treatment 7 years ago ( NO ADT), could a slowly rising PSA just be 'natural' as you age? Have always been curious, as when initial biopsy was ordered, the doctor said, "if you were a few months older (70), your PSA level would not have prompted further investigation
Researcher50
in
Advanced Prostate Cancer
5 months ago
Dad's PSA risen from 0.01 to 0.05 in 2 months, 2 years post SRT. Any chance that there is no further progression?
PSA has risen 3 times in a row. I understand the figure is still low, but is this a definite indication that it will progress, or is there a chance that PSA can stabilize or fluctuate and not progress further? Things have been difficult in the family, I am hoping for a miracle that he had a curative
PSA has risen 3 times in a row. I understand the figure is still low, but is this a definite indication that it will progress, or is there a chance that PSA can stabilize or fluctuate and not progress further? Things have been difficult in the family, I am hoping for a miracle that he had a curative
MsBoBo
in
Advanced Prostate Cancer
3 months ago
How to monitor PCa after you stop ADT?
I've been on Zoladex implants for coming up to 4 years in February. I plan to stop ADT next time when it's due, as my PSA is always "undetectable" and it's been 4 years of physical and mental torment for me (the side effects). I think that enough is enough now. Does anyone have advice on the best ways
I've been on Zoladex implants for coming up to 4 years in February. I plan to stop ADT next time when it's due, as my PSA is always "undetectable" and it's been 4 years of physical and mental torment for me (the side effects). I think that enough is enough now. Does anyone have advice on the best ways
BluesmanNick
in
Advanced Prostate Cancer
5 months ago
PSA drops with decreasing Testosterone
Here's a plot that I made from data taken from the PATCH estrogen patch therapy study. It plots the % reduction in PSA from baseline (100%) at time = 0 as a function of testosterone levels over a period of 4 weeks. As you know, estrogen effectively castrates men, causing a drop in testosterone over
Here's a plot that I made from data taken from the PATCH estrogen patch therapy study. It plots the % reduction in PSA from baseline (100%) at time = 0 as a function of testosterone levels over a period of 4 weeks. As you know, estrogen effectively castrates men, causing a drop in testosterone over
janebob99
in
Prostate Cancer Network
3 months ago
At the crossroads (again)
My profile is up to date, but, briefly, have failed chemo, ADT (am castrate resistant), failed Keytruda and now Pluvicto. Scans yest. & today show progression along with PSA rise. All my mets are in bone. So, my SOC choices are cabazataxel or radium 223. Other options are trial, which are a crapshoot
My profile is up to date, but, briefly, have failed chemo, ADT (am castrate resistant), failed Keytruda and now Pluvicto. Scans yest. & today show progression along with PSA rise. All my mets are in bone. So, my SOC choices are cabazataxel or radium 223. Other options are trial, which are a crapshoot
rsgdmd
in
Advanced Prostate Cancer
3 months ago
Rising PSA
I'm Poollover, Just got the results of a blood test and my PSA went up from 0.67 to 0.77. I'm on Orgovyx and Zytiga. I'm 86 years old. How concerned should I be? 8 months ago it was about 12. That was before medication. Also slightly anemic. What are my options? Terry
I'm Poollover, Just got the results of a blood test and my PSA went up from 0.67 to 0.77. I'm on Orgovyx and Zytiga. I'm 86 years old. How concerned should I be? 8 months ago it was about 12. That was before medication. Also slightly anemic. What are my options? Terry
Poollover
in
Advanced Prostate Cancer
3 months ago
Failed Pluvicto
Hello warriors, especially Tall Allen. I'm going on 6 years since Gleason 9 advanced metastatic diagnosis. Had a good run on Zytiga and all the usual other treatments, but just failed last ditch treatment of Pluvicto (after treatment 3). Did genetic testing and no significant mutations. My PSA is
Hello warriors, especially Tall Allen. I'm going on 6 years since Gleason 9 advanced metastatic diagnosis. Had a good run on Zytiga and all the usual other treatments, but just failed last ditch treatment of Pluvicto (after treatment 3). Did genetic testing and no significant mutations. My PSA is
jersy
in
Advanced Prostate Cancer
3 months ago
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