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First Patient Dosed in First-in-Human Phase 1/2a Clinical Trial of Autologous Neuronal Cell Replacement Therapy for Parkinson's Disease
Aspen Neuroscience, Inc. announced that the first patient has been dosed in the ASPIRO trial, a Phase 1/2a open label clinical trial to assess safety and tolerability of ANPD001, an autologous, dopaminergic neuron cell replacement therapy for participants with moderate to severe Parkinson's disease (
Aspen Neuroscience, Inc. announced that the first patient has been dosed in the ASPIRO trial, a Phase 1/2a open label clinical trial to assess safety and tolerability of ANPD001, an autologous, dopaminergic neuron cell replacement therapy for participants with moderate to severe Parkinson's disease (
Farooqji
in
Cure Parkinson's
1 month ago
Need advice on clinical trial RO7656594
I have updated our profile, but in a nutshell we've gone through abiraterone, Xtandi, docetaxel, Pluvicto , cabazitaxel and carboplatin. My husband's most recent PSA on 4/12 was 79.52. His MO has put a hold on chemo our last 3 appointments due to pancytopenia. He's received 2 blood transfusions on his
I have updated our profile, but in a nutshell we've gone through abiraterone, Xtandi, docetaxel, Pluvicto , cabazitaxel and carboplatin. My husband's most recent PSA on 4/12 was 79.52. His MO has put a hold on chemo our last 3 appointments due to pancytopenia. He's received 2 blood transfusions on his
Yadifan
in
Advanced Prostate Cancer
1 month ago
B12 deficiency: a hidden trigger of inflammation?
This was posted on the Pernicious Anaemia Society forum - but I thought it might be of interest to the many here who have inflammation. [i]News Release 17-Oct-2023[/i] [i]
B12 deficiency: a hidden trigger of inflammation?
[/i] [i]Peer-Reviewed Publication[/i] [i]Society of Chemical Industry[
This was posted on the Pernicious Anaemia Society forum - but I thought it might be of interest to the many here who have inflammation. [i]News Release 17-Oct-2023[/i] [i]
B12 deficiency: a hidden trigger of inflammation?
[/i] [i]Peer-Reviewed Publication[/i] [i]Society of Chemical Industry[
helvella
Thyroid UK
in
Thyroid UK
1 month ago
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Clinical trial update
Trial Drugs: Inavolisib and Giredestrant. Today was my second set of scans (every 8 weeks) and the results of the chest CT and Bone scans were great, nothing new, all stable and NED in lungs. The abdomen CT showed slight increase in the size of my liver lesions. I am ER+, HER2 low +1, PR-, AR+, with
Trial Drugs: Inavolisib and Giredestrant. Today was my second set of scans (every 8 weeks) and the results of the chest CT and Bone scans were great, nothing new, all stable and NED in lungs. The abdomen CT showed slight increase in the size of my liver lesions. I am ER+, HER2 low +1, PR-, AR+, with
Trissh
in
SHARE Metastatic Breast Cancer
1 month ago
Anyone participated in AMG 509 Clinical trial? - NCT04221542
Hello Please update us if you are participate in AMG 509. Anything you know about AMG 509 ? Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer
Hello Please update us if you are participate in AMG 509. Anything you know about AMG 509 ? Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer
God_Loves_Me
in
Advanced Prostate Cancer
1 month ago
What if?
I mentioned to you that one of the main premises of the Summit was to think about "what ifs" that we could change about how PBC is perceived and/or treated. One of these suggestions was "
what if
" we could totally eliminate the use of placebos in all clinical trials. Some of you may have participated
I mentioned to you that one of the main premises of the Summit was to think about "what ifs" that we could change about how PBC is perceived and/or treated. One of these suggestions was "
what if
" we could totally eliminate the use of placebos in all clinical trials. Some of you may have participated
DonnaBoll
Administrator
in
PBC Foundation
1 month ago
question for those who have stopped Lupron after many years of ADT
I have been on Lupron for 8 years with the short-term exception of a high/T clinical trial,( but even during the trial I stayed on Lupron). Anyway I’m undetectable and decided to stop Lupron. 3 months after not getting my shot my T is now a whopping 37. I am curious to hear from some of you who
I have been on Lupron for 8 years with the short-term exception of a high/T clinical trial,( but even during the trial I stayed on Lupron). Anyway I’m undetectable and decided to stop Lupron. 3 months after not getting my shot my T is now a whopping 37. I am curious to hear from some of you who
Chugach
in
Advanced Prostate Cancer
2 months ago
Feelings of loss
I had my son in October 2021 and was in an MBU for several months following that. It started with a manic episode, but then I went into a deep depression. At this point, I was so low that I would have happily traded my son to be well again and get my old life back. I was lucky and had great support from
I had my son in October 2021 and was in an MBU for several months following that. It started with a manic episode, but then I went into a deep depression. At this point, I was so low that I would have happily traded my son to be well again and get my old life back. I was lucky and had great support from
Alpav
in
Action on Postpartum Psychosis
1 year ago
Homeward bound...soon
Four amazing days have come to an end. Attending The International PBC Foundation Summit was nothing short of amazing ! Patients, patient advocates, nurses, and clinicians all together to make our lives better while educating others about our rare disease. There were several topics of "what if " that
Four amazing days have come to an end. Attending The International PBC Foundation Summit was nothing short of amazing ! Patients, patient advocates, nurses, and clinicians all together to make our lives better while educating others about our rare disease. There were several topics of "what if " that
DonnaBoll
Administrator
in
PBC Foundation
2 months ago
🧲🧠Stanford TMS Researchers treat depression by reversing brain signals traveling the wrong way
A new study led by Stanford Medicine researchers is the first to reveal how magnetic stimulation treats severe depression: by correcting the abnormal flow of brain signals. https://med.stanford.edu/news/all-news/2023/05/depression-reverse-brain-signals.html Stanford is a leading research group in the
A new study led by Stanford Medicine researchers is the first to reveal how magnetic stimulation treats severe depression: by correcting the abnormal flow of brain signals. https://med.stanford.edu/news/all-news/2023/05/depression-reverse-brain-signals.html Stanford is a leading research group in the
LifeIsThePitts
in
Anxiety and Depression Support
1 year ago
Have taken the plunge full Thyroid test!
Hi After reading many posts on here regarding Thyroid testing I have just received a full Thyroid Function test from Blue Horizon. My Thyroid has not been medicated correctly since I started taking 100mg Levothyroxine 4 yrs ago. Everytime I have a test the parameters seem to change from one test to
Hi After reading many posts on here regarding Thyroid testing I have just received a full Thyroid Function test from Blue Horizon. My Thyroid has not been medicated correctly since I started taking 100mg Levothyroxine 4 yrs ago. Everytime I have a test the parameters seem to change from one test to
Ontherun81
in
Thyroid UK
2 months ago
follow up post laparoscopy?
hello all, I hope you’re having a comfortable day. Can I ask what others have had experience of post lap with regards to appointments to discuss findings/treatment/recovery etc? (UK/NHS) I had my first laparoscopy last Tuesday. Confirmed endo and merina replaced. I am in a clinical trial so I
hello all, I hope you’re having a comfortable day. Can I ask what others have had experience of post lap with regards to appointments to discuss findings/treatment/recovery etc? (UK/NHS) I had my first laparoscopy last Tuesday. Confirmed endo and merina replaced. I am in a clinical trial so I
JEWM
in
Endometriosis UK
2 months ago
Anyone else finding the breastfeeding journey tough?
I am 8 weeks in and feeling so defeated today.... Our little one is still not gaining enough weight. Trying everything - formula, breastfeeding, tongue tie, cranial osteopathy.... So exhausted and emotional now after so many weeks working so hard.... I know others might be also going through this
I am 8 weeks in and feeling so defeated today.... Our little one is still not gaining enough weight. Trying everything - formula, breastfeeding, tongue tie, cranial osteopathy.... So exhausted and emotional now after so many weeks working so hard.... I know others might be also going through this
Hidden
in
Pregnancy and Parenting Support
1 year ago
Cancer takes another brave man
My wonderful husband passed away yesterday after fighting the beast for 15 years. Gleason 8 all but one core positive. He was so strong tried so hard, 2 clinical trials radiation, Zytiga, Xofigo, lupron for the entire time. Finally at age 65 his body could take no more, he lost over 40 pounds, no energy
My wonderful husband passed away yesterday after fighting the beast for 15 years. Gleason 8 all but one core positive. He was so strong tried so hard, 2 clinical trials radiation, Zytiga, Xofigo, lupron for the entire time. Finally at age 65 his body could take no more, he lost over 40 pounds, no energy
Judymin
in
Advanced Prostate Cancer
2 months ago
Autovaccination seems a hot topic lately: Mt. Sinai autovaccination technique to turn cold prostate cancer hot (Phase 1)
ok, I am exposing myself to j-o-h-n in more than one way with that title... This is for regional leagues (locally advanced PCa), while we are the NFL of prostate cancer here, but the fact that a cold cancer was turned hot is very promising as it has always been the main limit of immuno therapies applied
ok, I am exposing myself to j-o-h-n in more than one way with that title... This is for regional leagues (locally advanced PCa), while we are the NFL of prostate cancer here, but the fact that a cold cancer was turned hot is very promising as it has always been the main limit of immuno therapies applied
Maxone73
in
Advanced Prostate Cancer
2 months ago
Thyroid nodules surgery survey (BTF)
Posting this because helping with research is often a good idea. However, there are only three days to go! I've only just noticed it and have not gone through what they are asking for. [i]
Thyroid nodules surgery survey
[/i] [i]Complete a survey sharing your experiences of thyroid nodule surgery
Posting this because helping with research is often a good idea. However, there are only three days to go! I've only just noticed it and have not gone through what they are asking for. [i]
Thyroid nodules surgery survey
[/i] [i]Complete a survey sharing your experiences of thyroid nodule surgery
helvella
Thyroid UK
in
Thyroid UK
2 months ago
Not PCa but related. Imuno therapies keeps getting better.
On April 4, 2024, Candel Therapeutics, Inc. (the “Company”) issued a press release announcing positive interim data from its randomized phase 2 clinical trial of CAN-2409 in non-metastatic pancreatic cancer. A copy of the full press release is attached as Exhibit 99.1 to this Current Report on Form
On April 4, 2024, Candel Therapeutics, Inc. (the “Company”) issued a press release announcing positive interim data from its randomized phase 2 clinical trial of CAN-2409 in non-metastatic pancreatic cancer. A copy of the full press release is attached as Exhibit 99.1 to this Current Report on Form
Scout4answers
in
Advanced Prostate Cancer
2 months ago
Switching depression meds?
How to make it easier when switching depression medication so your partner and coworkers don't think you're crazy? I was on Lexapro and it made me manic, I've been weaning off and I now feel like a zombie who wants to cry all the time. My doctor wants me to start a mood stabilizer but I don't want my
How to make it easier when switching depression medication so your partner and coworkers don't think you're crazy? I was on Lexapro and it made me manic, I've been weaning off and I now feel like a zombie who wants to cry all the time. My doctor wants me to start a mood stabilizer but I don't want my
redmama2
in
Anxiety and Depression Support
1 year ago
Report Back from SGO: What’s New in Uterine Cancer (research)? IMPORTANT WEBINAR!
Friday, April 5 at 1-2pm ET If you haven't signed up for this, now's the time! It's good to sign up even if you can't attend at the webinar because SHARE will send you the link to the recording. https://www.sharecancersupport.org/report-back-from-sgo-whats-new-in-uterine-cancer-feb-2024/ Doctors
Friday, April 5 at 1-2pm ET If you haven't signed up for this, now's the time! It's good to sign up even if you can't attend at the webinar because SHARE will send you the link to the recording. https://www.sharecancersupport.org/report-back-from-sgo-whats-new-in-uterine-cancer-feb-2024/ Doctors
Merma
Moderator
in
SHARE Uterine Cancer Support
2 months ago
PSMA PET Results - don’t know what to do next (more tests?)
Hi everyone, For those who have been following my dad was diagnosed with PCa on Jan 18th, PI-RADS 5, Gleason 8, PSA 10.4. He started 50mg of Casodex on March 8, and had Eligard 30mg injection March 26th. He has had bone scan (nothing notable), CT (nothing notable), MRI showed one of his pelvic
Hi everyone, For those who have been following my dad was diagnosed with PCa on Jan 18th, PI-RADS 5, Gleason 8, PSA 10.4. He started 50mg of Casodex on March 8, and had Eligard 30mg injection March 26th. He has had bone scan (nothing notable), CT (nothing notable), MRI showed one of his pelvic
Cafu6
in
Advanced Prostate Cancer
2 months ago
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