Cannabis oil in treating Parkinson's disease

[Likii]

Case Reports

Braz J Biol

2025 Jan 17

Cannabis oil in treating Parkinson's disease: improvement of motor and non-motor symptoms: a case report

C T M I Issa, R D Castro, K L G D Albuquerque

Abstract

"... Despite the excellent results observed in clinical practice with the medicinal use of Cannabis in the treatment of PD, the level of scientific evidence is still limited due to the small number of studies published in this field. We present the case of a 77-year-old man diagnosed 22 years ago with PD in an advanced stage, with significant bradykinesia, tremor, and rigidity along with the inability to maintain an upright position and walk, exacerbated by a femur fracture. He also had advanced dysphagia, resulting in a gastrostomy. Although lucid, he showed no interest in conversation and tended to become depressed and isolated. He used Prolopa® with no satisfactory therapeutic response. After starting treatment with Cannabis sativa oil, he is now able to walk around the house frequently and eat pasty food regularly without choking or broncho-aspiration episodes. There has also been a significant improvement in non-motor symptoms; he is more active, cheerful, communicative, and attentive to his surroundings. ...

Conclusion

Although clinical cases ... have demonstrated neuroprotective effects, beneficial in delaying neurodegeneration, the precise molecular mechanisms are not well understood. Therefore, further studies are needed to clarify these mechanisms and to understand the subsequent slowing of neurodegeneration and the neuronal repair ...

Free Article: scielo.br/j/bjb/a/nqQFzz3Nt...

[Zscaleplanet]

Tried cannabis oil (high end and low end quality) more than once --- no effect, no improvement, nothing. Plus the link does not work -- at least for my computer.

[Hidden]

Yes I can agree with the article you have put up - my PWP has been on broad spectrum CBD for approx 4 years now and the improvement in mobility, gait, sleep, mood, posture, dysphagia has been very noticeable - tremors up and down at times. His dose used to be 5 drops morning and night - but now he just has 5-6 drops before bed and sleeps 6 - 8 hours where before he could only manage 3 - 4 hours.

[gomelgo]

i take CBD and CBN oil almost every day. It definitely feels good and calms my nerves which in turn calms tremor.