Can Valasta (astaxanthin) be the novel ap... - Cure Parkinson's
Can Valasta (astaxanthin) be the novel approach to reduce the symptoms of Parkinson’s?
Well @joel28 have you tried this wonderfully expensive ‘novel’ molecule.
If so do elaborate on the benefits it has brought to your Parkinson symptoms 🌺
astaxanthin appears to be available from other suppliers and is not terribly expensive
if you do a search under astaxanthin and shopping there are many brands available
Thanks! I am no stranger to Astaxanthin - I use it myself.
I just start to take the ValAsta, I will post the results as soon I see...
Thank you, look forward to your report ✨🥂✨
I use astaxanthin and the product you are going to be taking is very expensive($154 plus shipping) for 240 doses of 13. 5 mg of astaxanthin in olive oil and glucose. By comparison I take 24 mg per day which is approaching double the dose you will be taking and 240 doses costs only $43 and includes shipping.
The main effect I noticed is that it significantly reduced the time it takes me to do my two mile brisk morning walk and it prevents the muscle spasms I would occasionally get when walking at that brisk pace. I wrote about my experience with astaxanthin here :
healthunlocked.com/cure-par...
For those reasons I wouldn't be without it now, but in studies it has shown many more potential health benefits such as in these recent studies :
ncbi.nlm.nih.gov/pmc/articl...
ncbi.nlm.nih.gov/pmc/articl...
ncbi.nlm.nih.gov/pmc/articl...
Art
Art, the link to the product you use in the other thread no longer works. If you still use that product, could you post a new link? Thanks, Rebecca
Rebecca,
I updated the link in that article and this is a link to the 24 mg astaxanthin I use :
amazon.com/Astaxanthin-Supp...
Since I have been using it consistently since before I wrote that article, I opt to buy the 6 pack as it is a little less expensive that way. They describe the product as Liposomal Astaxanthin, but in other studies using astaxanthin, they have shown some effectiveness at less than 24 mg. This product has remained effective for me for the purpose that I wrote the article for.
Art
Some info from the Natural Medicines database; bioavailibility is low so delivery method is important. Best bet a lipid based formulation.
Pharmacokinetics
Absorption: Orally, astaxanthin is absorbed in the intestines (32658). However, because astaxanthin is a highly lipophilic compound, it has low bioavailability (32644). Human absorption of astaxanthin ranges from 6% to 34% after 4 hours (107961). The bioavailability may be increased when astaxanthin is encapsulated in a lipid-based formation (32622,32688). Also, the absorption of astaxanthin may be increased when taken after a meal (32682,107961).
Distribution: Animal research shows that, when taken orally, astaxanthin is largely distributed to muscle and heart tissue (32722). Astaxanthin can also cross the blood-brain barrier, as well as accumulate in the dermis and epidermis (96884).
Excretion: Preliminary clinical research shows that the elimination half-life of astaxanthin, taken orally at a dose of 40 mg, is about 16 hours, with a monophasic curve (32622). Other preliminary clinical research suggests that the elimination half-life of astaxanthin, taken orally at a dose of 100 mg, is about 52 hours (32632).
Antioxidant effects: Astaxanthin is a powerful antioxidant that is structurally similar to beta-carotene (8467). It contains the highest relative antioxidant activity when compared with alpha-tocopherol, alpha-carotene, beta-carotene, lutein, and lycopene (10634). Cell culture research shows that astaxanthin inhibits glycated protein/iron chelate-induced cytotoxicity by reducing the generation of reactive oxygen species (ROS) in human umbilical-vein endothelial cells (32680). Clinical research shows that taking astaxanthin 4-20 mg daily for 1 to 12 months reduces blood levels of malondialdehyde (MDA), a marker of oxidative stress (98768,107960). Interestingly, greater reductions in MDA are observed in patients with type 2 diabetes, and with doses of 11-13 mg daily. Additionally, astaxanthin may reduce levels of superoxide dismutase in overweight patients, but not in healthy individuals, when compared with placebo (107960). In patients with polycystic ovary syndrome (PCOS), astaxanthin improved the total antioxidant status but did not affect MDA, catalase, or superoxide dismutase (109775).
Some preliminary research suggests that the antioxidant effects of astaxanthin can protect against neurodegenerative diseases. Cell culture and animal research shows that astaxanthin prevents beta-amyloid-induced oxidative damage to red blood cells and dopaminergic cells. Theoretically this may help prevent the progression of Alzheimer disease and other dementias (32695,32702). Also, preliminary research in humans shows that astaxanthin can help reduce the accumulation of phospholipid hydroperoxides in erythrocytes. Abnormal accumulation of phospholipid hydroperoxides is associated with dementia (32700). Also, oxidative stress is thought to contribute to the pathogenesis of Parkinson disease. Cell culture and animal research shows that astaxanthin reduces oxidative stress-induced cytotoxicity of dopaminergic neurons, suggesting that it may protect against oxidative stress-induced neurodegeneration associated with Parkinson disease (32669,32673,32676,32697). Animal research also shows that the antioxidant effects of astaxanthin helps protect against ischemia-induced injury to brain tissue (32674).
Osasuna Liposomal Astaxanthin Supplement 24MG, Maximum Absorption - 120 Softgels
This one is supposedly increase bioavailability.
Astaxanthin is in Krill Oil! I have some going unused in my cupboard: sa1s3.patientpop.com/assets...
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