Interesting, Thoughts? Maybe already discussed, haven't seen it here though.
Nano Knife?: Interesting, Thoughts... - Advanced Prostate...
Nano Knife?
Be careful when considering local therapies other than SBRT (like laser, cryo, HIFU, etc). You need to be very confident you have low-grade capsule confined disease in my opinion for any of these things to be curative. My personal opinion is that in many cases these present an "easy out" for patients that are fearful of radiation and surgery which really should be their primary therapy. These local therapies are definitely good examples of something you want to get 2nd and 3rd opinions from Oncologists at centers of excellence.
I was the first one to get it as Sloan Kettering Hospital I have a tumor outside of the prostrate which was removed radiated over the years it seem to work for a period of time and the PSA came back again There were no side effects and not sure about the results the tumor was adjacent to a nerve bundle making it in operable best of luck
My friend tried this against the advise of our MO we shared. They missed the cancer and he ended up having to start over with seeds.
Schwah
I guess I should clarify, I am not the right person for this procedure at all. Just thought it might be of interest to some.
I did a search of our database and this is all I found:
Memorial Sloan Kettering, NYC
Nano Knife not the answer (yet) for Advanced Stage PCa, but May work well for some sensitive hard to get at areas. Phase 1 Trial underway w Nano Knife for Intermediate PCa.
Spyder54 profile image
Spyder54
in Advanced Prostate Cancer
7 months ago
Nano Knife. IRE (Irreversible Electro Prolation. Ok. Electro Magnetic killing of PCa without damage to surrounding organs!
Anyone have success or experience with IRE- Nano. Knife?Finally. I have been told that surgery, and Radiation not an option due to Bladder and Rectum involvement with Prostate tumor. IRE allows for ablation of tumor without damage to rectum or bladder.
Spyder54 profile image
Spyder54
in Advanced Prostate Cancer
10 months ago
Good News at 11 mos since Dx.
Looking into Nano Knife as it does not destroy surrounding tissue and can be repeated multiple times if needed. Will keep u posted. Do not want a Prostate that is cancerous or lymph nodes surrounding it. Best to you all, Mike St Pete
Spyder54 profile image
Spyder54
in Advanced Prostate Cancer
8 months ago
More on Nano Knife. This from MaleCare Newsletter which Darryl puts out. Wort subscribing. Mike
dailymail.co.uk/health/arti...
Spyder54 profile image
Spyder54
in Advanced Prostate Cancer
4 months ago
IRE-CT as a probable option
He's treated over 1000 patients with nano-knife and said many had SVI. The unevaluated addition is electro chemo-therapy (with Bleomycin) administered at the same time as the IRE.
CrocodileShoes profile image
CrocodileShoes
in Advanced Prostate Cancer
2 years ago
Lowering tumour burden in metastatic cancer
So, my question is this: if we worked on the assumption that micro-mets have occurred, is there still a benefit to having full-gland nano-knife treatment, with electro-chemo? I read somewhere that lowering the tumour burden would lengthen the time before ADT/Chemo regime would be necessary.
CrocodileShoes profile image
CrocodileShoes
in Advanced Prostate Cancer
3 years ago
Nano knife for locally advanced prostate cancer
Like to know about Nano knife therapy for APC... Any experience and how it is done... Is it better than IMRT Thanks
Karmaji profile image
Karmaji
in Advanced Prostate Cancer
3 years ago
Good Luck, Good Health and Good Humor.
j-o-h-n Tuesday 05/17/2022 6:04 PM DST
Good work ...nick danger..
Easy with a third eye............
Good Luck, Good Health and Good Humor.
j-o-h-n Tuesday 05/17/2022 8:26 PM DST
Firesign theatre. They were great! Out of the fog, into the smog… he’s nick danger. Third eye.
I had nanoknife treatment in Germany- with bleomycin given concurrently. PSA declined from around 20 to 3 within 3 months. At 6 months it was back up to 16. My tumor was large with extracapsular extension. As jazj noted above it probably will be most effective for those with smaller, organ contained lesions. As hospitals like MSK gain more experience, it may turn out to be a really viable focal treatment in that it doesn't damage tissues in the same way as thermally based methods. Apparently it can be repeated on same area. It was expensive and out of pocket, if $'s not an issue, might have returned for another PSMA scan and another round.
This article says it is for 5 cm size and below. You have to a general and they insert an electrode. The Cyberknife I had on my T-11 just required me to lie still for 50 minutes for 5 treatments over 2 weeks, with no SE's so far. They are considering it for my T-4 and due to being close to the esophagus I might have some discomfort swallowing for a couple of weeks. So, far a month of Lupron & Erleada have shrunk it to the point where it may not be needed.alexandriaradiology.com/unc....