Are you currently or scheduled to be ... - Advanced Prostate...
Are you currently or scheduled to be treated with Pluvicto? (We know there are factory shortages and want to gauge impact)
DarrylPartner182 Voters
l miss the “ I have had Pluvicto treatments” option
The treatment was put on hold this week as they told us the factory was shut down temporarily due to quality issues. Has anyone heard otherwise?
Any word on who shut them down, and what type of quality issues? I hope to get going soon on the Pluvicto, otherwise I imagine I'm looking at chemo!
I just completed your survey. Started 1st treatment feb1. Second treatment ( which is critical for me) is scheduled for March 15th 🤞🤞. Experiencing increased pain so need this 2nd one.
I started on Feb 1 as well. Have you had a PSA test yet? I just had one on Wed and my PSA dropped to 0.02, my lowest ever.
mine increased but not concerned ….yet. MO said it would most likely increase. Thinking long term… I have no choice.
Good luck with the treatment my friend.
we’re on a very similar journey. I was diagnosed in dec 2015 with a 212 psa. We have both fought hard over the past 7 years. This past 4 months has been the hardest of the 7 years specifically pain being the main driver.
we are on similar paths. Have you had chemo yet? I am in the Pluvicto trial for the chemo naive. I was shocked that my PSA dropped so low in the first month. If you are interested it’s the ECLIPSE trial.
Also missed the "waiting to be eligible for pluvicto treatment" option.
where is the “ I don’t need it yet” option.
this one: I am not currently treated with Pluvicto and have no interest in starting
that’s not the same.
Important topic for me (waiting for my six dates) and a close family member waiting for his 5th dose!
treatment was delayed two weeks due to quality issues
I had 6 sessions of Pluvicto (august 2021 - March 22) with exceptional results. PSA is now going up fast and I'm preparing for a second round of treatments.
Can you elaborate on "exceptional results". I just started two weeks ago with a PSA of around 300.
I started with PSA of 65. After sixth treatment it was just over 1. It continued to 0.64 a few months later. It going back up past 7 months so I’m going to do another round of pluvicto soon. Good luck!
also, my entire Lu-177 history is documented on healingwell.com. My name there is steve55777.
I have had two treatments so far and psa is dropping. I was told that you could only have 6 treatments. Is that not the case?
Technically, they say six treatments. But I'm not sure txs in Australia or Europe would turn you away after having done six txs, say the year before. I'm trying to push that limit here in the US. Wish me luck!
I’m sorry to hear it only worked for 7 months for you, I was kind of hoping it would have longer term benefit.
Pluvicto is a product from Novartis correct? What about Curium? Since that is a different company are they experiencing a shortage also?
Here is some further info fiercepharma.com/manufactur...
Not interested in starting because PSMA scan indicated no avidity
I was supposed to get dose #1 last Monday. No word on how long the delay will last so I switched to the only alternative left for me: cabazitaxel/carboplatin. I start tomorrow.
My MO had previously said that Lutetium-177-PSMA-617 was my best next step (sorry, I hate brand names). Yesterday, at our regular meeting, he said that they 're only servicing existing patients. They won't be adding new patients for six months to twelve months. That's reaching the outer limit of my projected OS. I'll need a different treatment (currently on PARPi for 5 months and may progress soon).
Right now, the plan is to try sequential BAT/Enzalutamide and hope for response. We'll fold in cabazitaxel/platinum chemo somewhere along the way. Hopefully that keeps me going until LU177 or AC255 become available.
Hey, there are plenty of places where you can get Pluvicto. Check out: us.pluvicto.com/treatment-c...
Have your doc write up an order and send it to local providers.
finished with all 6 treatments of Pluvicto back on 2/7/23
How were results?
I’m taking xtandi along with the pluvicto. My PSA drop initially but we noticed at the time of my 5th treatment (Dec2022) my PSA was starting to rise. It was still climbing slightly at my 6th treatment. The cancer was figuring a way around the treatment. I have a PET-PSMA scan scheduled for mid-march. At that time we’ll figure out the next step. I’m sorry to say, but we’re running out of tools in the tool box.
Hang in there. I think that while the PSA is climbing near the end of Pluvicto, the Pluvicto is still helping. It would likely be much worse had you not done the Pluvicto treatments. I think we have the same toolbox--keep as positive as you can--that, I also believe, is one of the tools... Steve
👍
I'm curious what patients thought process is on deciding to take this drug. The VISION clinical trial shows that it adds on average 4 months to overall survival. Yes 4 months is 4 months, but, that doesn't come at no cost (both to the insurance company and/or patient) and the side effects that come with it.
6 IV treatments, one every six weeks with the chance of having to have a blood transfusion amongst other milder side effects. If you know it's not a cure and in the context of an entire lifetime is not going to add signficant time to your life (that's of course subjective), is a shortage really that big of a game changer?
Are PCa patients getting more benefit than 4 months out of this drug which is driving the demand?
4 months may not sound like a lot, but when you're looking at a 6 month projected OS it becomes much more attractive.
It's QOL as much as anything. Hubby has his life back for the first time since he was diagnosed. We don't even think about OS, we're just enjoying every day as it comes. It's given us a second honeymoon -- actually a first because he was diagnosed just before we were married and it felt as if we were behind the eight ball thereafter. Far as we're concerned it is a miracle.
if I were to judge what it’s done for me, it’s given me a year and a half. PSA start 65. PSA 18 months later back to 65. And I’m getting another round of it soon.
Am interested but it's still in trial stage here in Japan.
