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Alendronic acid / Colecalciferol
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Exciting!
CymaBay Submits New Drug Application to FDA for Seladelpar for the Treatment of Primary Biliary Cholangitis December 15, 2023 8:00am EST Download as PDF - NDA is supported by data evaluating seladelpar efficacy and safety in over 500 patients - - Seladelpar is the first New Drug Application from
CymaBay Submits New Drug Application to FDA for Seladelpar for the Treatment of Primary Biliary Cholangitis December 15, 2023 8:00am EST Download as PDF - NDA is supported by data evaluating seladelpar efficacy and safety in over 500 patients - - Seladelpar is the first New Drug Application from
DonnaBoll
Administrator
in
PBC Foundation
4 months ago
is everyone else not getting diagnosed or much treatment?
I’ve had severe period pain for years, when I wasn’t taking painkiller in time I would be sick and feel faint. I have tried paracetamol and ibuprofen in the pad which did nothing. I took naproxen 500mg which used to completely block my pain but now only stops it being severe. More recently I’ve been
I’ve had severe period pain for years, when I wasn’t taking painkiller in time I would be sick and feel faint. I have tried paracetamol and ibuprofen in the pad which did nothing. I took naproxen 500mg which used to completely block my pain but now only stops it being severe. More recently I’ve been
pinkie25
in
Endometriosis UK
4 months ago
Do people feel their doctors told them what they need to know?
I was diagnosed just after the start of the pandemic. It was lockdown = pandemonium. All the same it sticks in my mind that all I was told about Pred was when to take it and to reduce.. Really, they seemed most concerned about alendronic acid and how I must sit upright. Do people risk death if they
I was diagnosed just after the start of the pandemic. It was lockdown = pandemonium. All the same it sticks in my mind that all I was told about Pred was when to take it and to reduce.. Really, they seemed most concerned about alendronic acid and how I must sit upright. Do people risk death if they
Mayadill
in
PMRGCAuk
1 year ago
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AIHdx
Hi! New here. I had been experiencing vague, debilitating symptoms occasionally for a few years, fatigue, nausea, chronic back pain, itchy skin, brain fog, etc. November’23 symptoms became acute, as well as dark urine and jaundice and I was basically incapacitated. Hospitalized December’23 with ALT
Hi! New here. I had been experiencing vague, debilitating symptoms occasionally for a few years, fatigue, nausea, chronic back pain, itchy skin, brain fog, etc. November’23 symptoms became acute, as well as dark urine and jaundice and I was basically incapacitated. Hospitalized December’23 with ALT
AIGal73
in
British Liver Trust
4 months ago
Alpha-lipoic acid
Hi! Has anyone on here used a Alpha-lipoic acid supplement, to help remove heavy metals from the body? If so . . . Did you see good results? . . . And if the results were good, can anyone recommend a brand and where they got it from? Thank you, Tracy
Hi! Has anyone on here used a Alpha-lipoic acid supplement, to help remove heavy metals from the body? If so . . . Did you see good results? . . . And if the results were good, can anyone recommend a brand and where they got it from? Thank you, Tracy
T108
in
Early CKD Support
4 months ago
shortness of breath subsequent to zoledronic acid infusion
Because of GI problems, bisphosphonate tablets are not an option for me, so I have gone down the infusion path. I had my first infusion on December 28th, and experienced about three days of bad muscle pain, which then resolved itself. It was a couple of weeks later that I noticed that my ankles were
Because of GI problems, bisphosphonate tablets are not an option for me, so I have gone down the infusion path. I had my first infusion on December 28th, and experienced about three days of bad muscle pain, which then resolved itself. It was a couple of weeks later that I noticed that my ankles were
Angel_doll
in
PMRGCAuk
5 months ago
Endometriosis
I've had period pain since I was 15 and each year the pain only gets worse. When I became 18, the pain became crippling. The pain will start mildly a week or two before I start my period. Then when I start my period the pain intensifies. I find it hard to walk, I feel like I have a fever then have an
I've had period pain since I was 15 and each year the pain only gets worse. When I became 18, the pain became crippling. The pain will start mildly a week or two before I start my period. Then when I start my period the pain intensifies. I find it hard to walk, I feel like I have a fever then have an
Tigerlily34
in
Women's Health
5 months ago
Endo diagnosis
I've had period pain since I was 15 and each year the pain only gets worse. When I became 18, the pain became crippling. The pain will start mildly a week or two before I start my period. Then when I start my period the pain intensifies. I find it hard to walk, I feel like I have a fever then have an
I've had period pain since I was 15 and each year the pain only gets worse. When I became 18, the pain became crippling. The pain will start mildly a week or two before I start my period. Then when I start my period the pain intensifies. I find it hard to walk, I feel like I have a fever then have an
Tigerlily34
in
Endometriosis UK
5 months ago
zoledronic acid infusion and osteoarthritis
I have been reading about zoledronic acid does not help with osteoarthritis and may make it worse, I have marked facet arthropathy in the lower lumbar spine arthritis, anyone know anything about this.
I have been reading about zoledronic acid does not help with osteoarthritis and may make it worse, I have marked facet arthropathy in the lower lumbar spine arthritis, anyone know anything about this.
Radars
in
Bone Health and Osteoporosis UK
5 months ago
Vitamin D3 Necessity?
Hi all, I'm a GCA patient, having started at 60 MG in AUG 2022. I'm down to 12.5 MG today. I have felt lousy in so many respects including fatigue, vision issues, and GI problems since day 1. When the rheumy put me on Alendronic Acid a month of so ago, that was the "last straw." It made me feel
Hi all, I'm a GCA patient, having started at 60 MG in AUG 2022. I'm down to 12.5 MG today. I have felt lousy in so many respects including fatigue, vision issues, and GI problems since day 1. When the rheumy put me on Alendronic Acid a month of so ago, that was the "last straw." It made me feel
montebello
in
PMRGCAuk
1 year ago
Immune suppression caused by Urso
Hi all, I only recently learned that Urso has suppressive effects on the immune system. One research paper I read, and there are others, lists the effects - apologies for scientific jargon! Urso suppresses the production of immunoglobulins IgA, IgG and IgM (although IgM is generally chronically raised
Hi all, I only recently learned that Urso has suppressive effects on the immune system. One research paper I read, and there are others, lists the effects - apologies for scientific jargon! Urso suppresses the production of immunoglobulins IgA, IgG and IgM (although IgM is generally chronically raised
Skypony
in
PBC Foundation
5 months ago
I am now able to tolerate antibiotics again after my nerves healed
Hello! I just want to give this update about my situation. I hope people on here find this because my situation was a nightmare and I think this can help people who are confused and not sure what to do or if they'll ever be able to tolerate antibiotics again (TL;DR: you will be able to if you can heal
Hello! I just want to give this update about my situation. I hope people on here find this because my situation was a nightmare and I think this can help people who are confused and not sure what to do or if they'll ever be able to tolerate antibiotics again (TL;DR: you will be able to if you can heal
Whoa182
in
Pernicious Anaemia Society
5 months ago
Ibandronic Acid
With aggravated osteoporosis my partner has been offered the choice of monthly doses of Bonviva or a six monthly injection. Which would be most effective to mitigate the osteoporosis while remaining compatible with an AF/pacemaker regime that includes Amias, Sotalol, Furosemide, and Apixaban?.
With aggravated osteoporosis my partner has been offered the choice of monthly doses of Bonviva or a six monthly injection. Which would be most effective to mitigate the osteoporosis while remaining compatible with an AF/pacemaker regime that includes Amias, Sotalol, Furosemide, and Apixaban?.
rathlee
in
AF Association
5 months ago
marked facet arthropathy lower lumbar spine
I have also been diagnosed with spinal arthropathy anyone else got this this, I wander if zoledronic acid infusion will be any help with this.
I have also been diagnosed with spinal arthropathy anyone else got this this, I wander if zoledronic acid infusion will be any help with this.
Radars
in
Bone Health and Osteoporosis UK
5 months ago
IV Zoledronic acid.
unfortunately time to move to Zoledronic acic fractures happening. Tried calcium and Vit D weight bearing exercises. Has anybody got any advice before I travel down the road of no return!!! thank you in advance.
unfortunately time to move to Zoledronic acic fractures happening. Tried calcium and Vit D weight bearing exercises. Has anybody got any advice before I travel down the road of no return!!! thank you in advance.
Lion321
in
Advanced Prostate Cancer
5 months ago
Pain relief advice
Hi, I had a laprocospy in November 2022. Since then I have had a miscarriage and been really struggling with ongoing severe pain and swelling. Awaiting a further laprocospy but this could be 12-18 months before I get a date. I have been contemplating going privately or trying GnRh injections until I
Hi, I had a laprocospy in November 2022. Since then I have had a miscarriage and been really struggling with ongoing severe pain and swelling. Awaiting a further laprocospy but this could be 12-18 months before I get a date. I have been contemplating going privately or trying GnRh injections until I
November22
in
Endometriosis UK
5 months ago
PMR seems to have returned
Briefly, I had PMR from 2016 - 2019. It didn’t show up on blood test and I was started on 15mg of pred. Within 48 hours I was pain free and quickly reduced to 10mg then dead slow method. After having very painful shoulders and top of arms for the last 3 months (which did not respond to painkillers
Briefly, I had PMR from 2016 - 2019. It didn’t show up on blood test and I was started on 15mg of pred. Within 48 hours I was pain free and quickly reduced to 10mg then dead slow method. After having very painful shoulders and top of arms for the last 3 months (which did not respond to painkillers
Urtica
in
PMRGCAuk
1 year ago
Is all the extra medication needed?
Hello everyone. I was diagnosed with PMR just over 2 years ago and have posted on this invaluable site a few times. After high doses of Pred at the beginning with a possible threat of GCA,, which did not occur, I have yo-yoed a bit with stresses in life. However I am currently on 7 and a half mg and
Hello everyone. I was diagnosed with PMR just over 2 years ago and have posted on this invaluable site a few times. After high doses of Pred at the beginning with a possible threat of GCA,, which did not occur, I have yo-yoed a bit with stresses in life. However I am currently on 7 and a half mg and
Stargiver
in
PMRGCAuk
5 months ago
Has 3 years on Prednisolone caused all these problems?
Hi All,I haven't posted for a while but regularly read the daily highlights and continue to learn about our condition and take comfort that there are others who understand the difficulties we face living with PMR. The last few weeks, have been challenging for a few reasons. I'm currently 3 weeks into
Hi All,I haven't posted for a while but regularly read the daily highlights and continue to learn about our condition and take comfort that there are others who understand the difficulties we face living with PMR. The last few weeks, have been challenging for a few reasons. I'm currently 3 weeks into
CarolF1312
in
PMRGCAuk
11 months ago
Itching for answers.... thankyou!
(Me = 80/JAK2 /ET/Hydroxycarbamide for 13years) I am very grateful to everyone that has replied to my list of queries about itching/pruritis. I have been aware for some years that it is a subject that has been repeatedly raised but felt that there did not seem to be a firm definition of cause or solution
(Me = 80/JAK2 /ET/Hydroxycarbamide for 13years) I am very grateful to everyone that has replied to my list of queries about itching/pruritis. I have been aware for some years that it is a subject that has been repeatedly raised but felt that there did not seem to be a firm definition of cause or solution
quanglewangle
in
MPN Voice
5 months ago
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