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I want to give up
Over about the past month, I have spiraled into severe anxiety and depression. I've struggled to get out of bed and sometimes haven't. It has affected by work as a lawyer, my family/kids and the relationship with my girlfriend. I feel abandoned by my family (which isn't quite true or fair, but also
Over about the past month, I have spiraled into severe anxiety and depression. I've struggled to get out of bed and sometimes haven't. It has affected by work as a lawyer, my family/kids and the relationship with my girlfriend. I feel abandoned by my family (which isn't quite true or fair, but also
Gandolfication
in
Anxiety and Depression Support
10 months ago
castration after 7 years of ADT
I have been on Zoladex for nearly 7 years and am fully over any regrets of Chemical castration. My psa is now slowly rising and ghastly taken 2 years from undetectable to 0.65. I am considering surgical castration now as it would mean no more 3 monthly Zoladex injections and a reduced chemical load on
I have been on Zoladex for nearly 7 years and am fully over any regrets of Chemical castration. My psa is now slowly rising and ghastly taken 2 years from undetectable to 0.65. I am considering surgical castration now as it would mean no more 3 monthly Zoladex injections and a reduced chemical load on
Roscoaus2000
in
Advanced Prostate Cancer
7 months ago
When to take bisoprolol ?
Hi , My husband is on 7.5 in the morning and I’ve reduced him to 5 in the evening as he has been so tired all the time . They only upped it by 2.5 when I rang heart function nurse when his ecg on his watch was creeping up to 130 . He was on digoxin before which seemed to keep his ecg around 89/90 but
Hi , My husband is on 7.5 in the morning and I’ve reduced him to 5 in the evening as he has been so tired all the time . They only upped it by 2.5 when I rang heart function nurse when his ecg on his watch was creeping up to 130 . He was on digoxin before which seemed to keep his ecg around 89/90 but
Jackiesmith7777
in
AF Association
7 months ago
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Curcumin (Theracurmin) Improves Mild Cognitive Impairment and Memory - A Randomized Clinical Trial
This is a remarkable study of the effects of a highly bioavailable form of Curcumin, "Theracurmin", on memory in non-demented aging adults, including those diagnosed with MCI, Mild Cognitive Impairment. What we call "Chemo-Brain" is a form of MCI resulting from cancer treatments including chemotherapy
This is a remarkable study of the effects of a highly bioavailable form of Curcumin, "Theracurmin", on memory in non-demented aging adults, including those diagnosed with MCI, Mild Cognitive Impairment. What we call "Chemo-Brain" is a form of MCI resulting from cancer treatments including chemotherapy
MateoBeach
in
Fight Prostate Cancer
1 year ago
First Post - Flecainide with Diltiazem
Hi, my first post but have been a member and avid reader of all your posts (which have been very informative) since joining in Feb 22 when diagnosed with AFib. Question - does anyone have experience of taking Diltiazem alongside Flecainide, and if so, has that been ok in terms of QoL and side effects
Hi, my first post but have been a member and avid reader of all your posts (which have been very informative) since joining in Feb 22 when diagnosed with AFib. Question - does anyone have experience of taking Diltiazem alongside Flecainide, and if so, has that been ok in terms of QoL and side effects
Bobbins58
in
AF Association
7 months ago
No more propafenone!!!! What???
I'm in the U.S., diagnosed PAF ~3 years ago. Have achieved excellent control with propafenone (Rythmol). My pharmacy informed me they cannot refill my prescription, as there is a supply side problem with propafenone. From what I have read, there is a dangerous shortage of propafenone in the U.S and
I'm in the U.S., diagnosed PAF ~3 years ago. Have achieved excellent control with propafenone (Rythmol). My pharmacy informed me they cannot refill my prescription, as there is a supply side problem with propafenone. From what I have read, there is a dangerous shortage of propafenone in the U.S and
frazeej
in
AF Association
7 months ago
cardioversion
How do people feel being in persistent AF? I have an appointment for a cardioversion pre op on Thursday after being told after an angiogram that everything the arteries were fine but I was in persistent AF. I have no symptoms and feel absolutely fine, the consultant did double my bisoprolol to lower
How do people feel being in persistent AF? I have an appointment for a cardioversion pre op on Thursday after being told after an angiogram that everything the arteries were fine but I was in persistent AF. I have no symptoms and feel absolutely fine, the consultant did double my bisoprolol to lower
Patchwork123
in
AF Association
7 months ago
low heart rate
hi, I was in hospital 6 weeks ago with a bad attack of A Fib. Came as a shock as I’d had palpitations on and off for a few seconds but nothing lasting hours. I was given Bisopropol and edoxaban to go along with the Ramipril and Amlodopine I was already on. The beta blocker must have worked as I went
hi, I was in hospital 6 weeks ago with a bad attack of A Fib. Came as a shock as I’d had palpitations on and off for a few seconds but nothing lasting hours. I was given Bisopropol and edoxaban to go along with the Ramipril and Amlodopine I was already on. The beta blocker must have worked as I went
Anonyscouse
in
AF Association
7 months ago
Heart rate 214bpm
Hi, should I be worried? This afternoon went into a AF episode after my last one 3 weeks ago, currently on waiting list for my second ablation, now 17 months in.usually when I’m in an episode my heart rate tops is 140 bpm. Suddenly whilst in AF my heart went up 214 bpm, felt faint and very hot. Phoned
Hi, should I be worried? This afternoon went into a AF episode after my last one 3 weeks ago, currently on waiting list for my second ablation, now 17 months in.usually when I’m in an episode my heart rate tops is 140 bpm. Suddenly whilst in AF my heart went up 214 bpm, felt faint and very hot. Phoned
Lesleyray
in
AF Association
7 months ago
Diltiazem with Flecanaide
I'm 69 and I have lived with Paroxymal AFib for 20 yrs with episodes every few months, After taking Flecanaide, 200mg per day, for 15 years I have been taken off it as it has recently started to affect my heart rate taking it up to and sometimes over 130bpm regularly. I now take 120mg Diltiazem Prolonged
I'm 69 and I have lived with Paroxymal AFib for 20 yrs with episodes every few months, After taking Flecanaide, 200mg per day, for 15 years I have been taken off it as it has recently started to affect my heart rate taking it up to and sometimes over 130bpm regularly. I now take 120mg Diltiazem Prolonged
iggyrich
in
AF Association
7 months ago
I have been signed off from my care at hospital after 10 years of A fib and a stroke
I had a letter from my hospital that was dealing with my last ablation in 2019 , ECG ‘s etc . That they would no longer be looking after me - 2 weeks ago. I went back into A fib summer of 2020 during covid , I had to self assess my medication and my heart rate via my watch . I could see no one because
I had a letter from my hospital that was dealing with my last ablation in 2019 , ECG ‘s etc . That they would no longer be looking after me - 2 weeks ago. I went back into A fib summer of 2020 during covid , I had to self assess my medication and my heart rate via my watch . I could see no one because
01maxdog
in
AF Association
7 months ago
GCA diagnostic dilemma
Thank you everyone who has helped so far. Last night I had a message from Rheumy saying I should go to the hospital for an emergency biopsy, with the headache and unusual severe temporal pain being the driver. He said that U/S was so ‘operator sensitive’ as to be unreliable in this ‘locality’. The
Thank you everyone who has helped so far. Last night I had a message from Rheumy saying I should go to the hospital for an emergency biopsy, with the headache and unusual severe temporal pain being the driver. He said that U/S was so ‘operator sensitive’ as to be unreliable in this ‘locality’. The
Predderman2020
in
PMRGCAuk
7 months ago
After High Intensity Interval Exercise, fT4/ fT3 up from 'normal', 12 hours later both down from 'normal'. Both return to 'normal' by 72hrs
Interesting study discussing the effects of high intensity interval training on : conversion of T4 to T3 . conversion of T4 to rT3 . and CORTISOL. ~ Study is done on healthy fit subjects, so obviously we must assume their healthy functioning thyroid gland also had some involvement in proceedings
Interesting study discussing the effects of high intensity interval training on : conversion of T4 to T3 . conversion of T4 to rT3 . and CORTISOL. ~ Study is done on healthy fit subjects, so obviously we must assume their healthy functioning thyroid gland also had some involvement in proceedings
tattybogle
in
Thyroid UK
1 year ago
Living Cell Technologies announces continued progress on its third clinical trial to assess NTCELL
Living Cell Technologies announces continued progress on its third clinical trial to assess NTCELL in people with #Parkinsons (in collaboration with Nzeno) http://www.irasia.com/listco/au/lct/halfyr/2023/intpress.htm
Living Cell Technologies announces continued progress on its third clinical trial to assess NTCELL in people with #Parkinsons (in collaboration with Nzeno) http://www.irasia.com/listco/au/lct/halfyr/2023/intpress.htm
Hidden
in
Cure Parkinson's
1 year ago
Medical OR chemical castration
Hi All, Ok I am 79 and still in great physical condition. PR and ADT for 2 years. To date no unusual physical side effects other than zero sex drive. It looks as thought I will be on ADT until I die. PSA increasing monthly so I will try other chemicals. I want to remain in good shape until my number
Hi All, Ok I am 79 and still in great physical condition. PR and ADT for 2 years. To date no unusual physical side effects other than zero sex drive. It looks as thought I will be on ADT until I die. PSA increasing monthly so I will try other chemicals. I want to remain in good shape until my number
Stevegr
in
Advanced Prostate Cancer
7 months ago
Inhibikase Therapeutics Announces FDA has Lifted the Full Clinical Hold on IkT-148009 in Parkinson's Disease
https://www.inhibikase.com/news/press-releases/detail/72/inhibikase-therapeutics-announces-fda-has-lifted-the-full "We are grateful for the expeditious review by the FDA of our response to the Clinical Hold on IkT-148009 in PD," stated Milton H. Werner, Ph.D., President and Chief Executive Officer
https://www.inhibikase.com/news/press-releases/detail/72/inhibikase-therapeutics-announces-fda-has-lifted-the-full "We are grateful for the expeditious review by the FDA of our response to the Clinical Hold on IkT-148009 in PD," stated Milton H. Werner, Ph.D., President and Chief Executive Officer
Hidden
in
Cure Parkinson's
1 year ago
Beware of ultrasound treatment for Parkinson’s disease!
I participated in a clinical trial of focused ultrasound treatment for Parkinson’s disease. I was treated at Stanford University hospital. 15 participants were given the treatment, but I was one of the five participants assigned to the placebo group. The assignment was blinded.to participants. In the
I participated in a clinical trial of focused ultrasound treatment for Parkinson’s disease. I was treated at Stanford University hospital. 15 participants were given the treatment, but I was one of the five participants assigned to the placebo group. The assignment was blinded.to participants. In the
Pitchfixer
in
Cure Parkinson's
1 year ago
Affect of tummy upsets on anti-coagulants,
I was wondering what effect it has on the absorption of anti-coagulants, should something cause you to have diarrhoea - how long does it take after ingestion does it take something like an Eliquis tablet to become effective ?
I was wondering what effect it has on the absorption of anti-coagulants, should something cause you to have diarrhoea - how long does it take after ingestion does it take something like an Eliquis tablet to become effective ?
pusillanimous
in
AF Association
7 months ago
Selegiline run out
I was told recently by my pharmacist they couldn't get any Selegiline and to ask my GP for an alternative. I still have 60 10mg tablets left and will have to inform GP soon. (I'm still waiting on my first appointment with neurologist in my new location, been waiting months as unfortunately I had to
I was told recently by my pharmacist they couldn't get any Selegiline and to ask my GP for an alternative. I still have 60 10mg tablets left and will have to inform GP soon. (I'm still waiting on my first appointment with neurologist in my new location, been waiting months as unfortunately I had to
Ardbeg28
in
Cure Parkinson's
10 months ago
ESMO 2023: PSMAfore Phase 3 Trial of [177Lu]Lu-PSMA-617 in Taxane-Naive Patients with Metastatic Castration Resistant Prostate Cancer
Apologies if this was already posted: https://www.urotoday.com/conference-highlights/esmo-2023/esmo-2023-prostate-cancer/147587-esmo-2023-psmafore-phase-3-trial-of-177lu-lu-psma-617-in-taxane-naive-patients-with-mcrpc.html
Apologies if this was already posted: https://www.urotoday.com/conference-highlights/esmo-2023/esmo-2023-prostate-cancer/147587-esmo-2023-psmafore-phase-3-trial-of-177lu-lu-psma-617-in-taxane-naive-patients-with-mcrpc.html
swwags
in
Advanced Prostate Cancer
7 months ago
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