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Phenelzine
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Phenelzine
Phenelzine
is a maoMao inhibitor with the differencethaydifference that it only raises dopamine in the central nervous central system. LIfe changer for me, but make you talk to a drDr, so many medicines can interact.
Phenelzine
is a maoMao inhibitor with the differencethaydifference that it only raises dopamine in the central nervous central system. LIfe changer for me, but make you talk to a drDr, so many medicines can interact.
toobs1234
in
Restless Legs Syndrome
5 months ago
The MAO inhibitors phenelzine and clorgyline revert enzalutamide resistance in castration resistant prostate cancer
I am not using enza (yet) wondering if it's worth taking some nutmeg to keep those mao in check anyway! :-P https://www.nature.com/articles/s41467-020-15396-5
I am not using enza (yet) wondering if it's worth taking some nutmeg to keep those mao in check anyway! :-P https://www.nature.com/articles/s41467-020-15396-5
Maxone73
in
Fight Prostate Cancer
5 months ago
Monoamine oxidase A (MAOA): A promising target for prostate cancer therapy
A clinical trial of a MAOA inhibitor (
phenelzine
sulfate) (2010) was terminated due to poor accrual [2].
A clinical trial of a MAOA inhibitor (
phenelzine
sulfate) (2010) was terminated due to poor accrual [2].
pjoshea13
in
Fight Prostate Cancer
1 year ago
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Side effects of levodopa
. • An allergy to carbidopa, levodopa, or any other part of the medicine • Narrow-angle glaucoma, history of melanoma, unexplained skin spots • Whether you have taken a monoamine oxidase inhibitor (
phenelzine
, tranylcypromine, isocarboxazid) in the last 14 days
. • An allergy to carbidopa, levodopa, or any other part of the medicine • Narrow-angle glaucoma, history of melanoma, unexplained skin spots • Whether you have taken a monoamine oxidase inhibitor (
phenelzine
, tranylcypromine, isocarboxazid) in the last 14 days
Farooqji
in
Cure Parkinson's
2 years ago
Patient satisfaction with antidepressants -- old drugs come out top
Regardless, old medications
Phenelzine
and Tranylcypromine came out top of the list for patient satisfaction. Also the tricyclic Clomipramine did well. 3 of the top 4 places went to monoamine oxidase inhibitors.
Regardless, old medications
Phenelzine
and Tranylcypromine came out top of the list for patient satisfaction. Also the tricyclic Clomipramine did well. 3 of the top 4 places went to monoamine oxidase inhibitors.
_Alex_
in
Anxiety and Depression Support
4 years ago
Therapy session tomorrow
Buspirone - 3star
phenelzine
(Nardil)-1star tranylcypromine (Parnate)-2star clonazepam- 4stars alprazolam-4stars hydroxyzine- 4stars Open to any suggestions
Buspirone - 3star
phenelzine
(Nardil)-1star tranylcypromine (Parnate)-2star clonazepam- 4stars alprazolam-4stars hydroxyzine- 4stars Open to any suggestions
Blu_A25
in
Anxiety and Depression Support
4 years ago
Article on phenelzine shortage
https://www.9news.com.au/national/without-nardil-ill-die-brisbane-man-flies-to-us-to-buy-up-discontinued-antidepressant-drug/1bd6b34b-93da-47ae-8016-6fa204e89cea
https://www.9news.com.au/national/without-nardil-ill-die-brisbane-man-flies-to-us-to-buy-up-discontinued-antidepressant-drug/1bd6b34b-93da-47ae-8016-6fa204e89cea
_Alex_
in
Anxiety and Depression Support
4 years ago
Clorgyline for Enzalutamide resistance.
"Targeting MAO-A with
phenelzine
or clorgyline, the FDA-approved drugs for antidepression, resensitize the Enz resistant (EnzR) cells to Enz treatment and further suppress EnzR cell growth in vitro [i]and in vivo[/i]." Worth a try? -Patrick [1] https://pubmed.ncbi.nlm.nih.gov/32483206/?
"Targeting MAO-A with
phenelzine
or clorgyline, the FDA-approved drugs for antidepression, resensitize the Enz resistant (EnzR) cells to Enz treatment and further suppress EnzR cell growth in vitro [i]and in vivo[/i]." Worth a try? -Patrick [1] https://pubmed.ncbi.nlm.nih.gov/32483206/?
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Phenelzine and PSA/PCa study
https://ellison.usc.edu/2020/03/03/maoi-prostate-cancer/?fbclid=IwAR127dztEVujlXJm_kaXQGfIoMDyJAIDbVxSDkFJ2HnG3CsYqHPyrBzYz3w
https://ellison.usc.edu/2020/03/03/maoi-prostate-cancer/?fbclid=IwAR127dztEVujlXJm_kaXQGfIoMDyJAIDbVxSDkFJ2HnG3CsYqHPyrBzYz3w
dockam
in
Advanced Prostate Cancer
4 years ago
Repurposed antidepressant could be a new treatment for recurrent prostate cancer 6:03 March 3, 2020
The drug — an MAO inhibitor called
phenelzine
— represents a potential new treatment direction with fewer side effects for men with recurrent prostate cancer, researchers said.
The drug — an MAO inhibitor called
phenelzine
— represents a potential new treatment direction with fewer side effects for men with recurrent prostate cancer, researchers said.
JLS1
in
Advanced Prostate Cancer
4 years ago
Phenelzine/Nardil
Anyone out there taking reasonably high doses of
Phenelzine
(Nardil)? I would like to hear how you space out your daily doses and whether mania/excessive euphoria affects you. Thanks
Anyone out there taking reasonably high doses of
Phenelzine
(Nardil)? I would like to hear how you space out your daily doses and whether mania/excessive euphoria affects you. Thanks
fuji4129
in
Anxiety and Depression Support
5 years ago
From MAOI to MAOI
So, I don't know if it's over yet, but the drought of Nardil (
phenelzine
) here in the UK meant I had to come off of it. The stress of finding enough supply to allow titrating down & off Nardil was terrifying! But at the same time, I was also relieved.
So, I don't know if it's over yet, but the drought of Nardil (
phenelzine
) here in the UK meant I had to come off of it. The stress of finding enough supply to allow titrating down & off Nardil was terrifying! But at the same time, I was also relieved.
MaskedNinja
in
Anxiety and Depression Support
5 years ago
Monoamine oxidase.
Along with tranylcypromine and isocarboxazid,
phenelzine
is one of the few non-selective and irreversible MAOIs still in widespread clinical use.
Along with tranylcypromine and isocarboxazid,
phenelzine
is one of the few non-selective and irreversible MAOIs still in widespread clinical use.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Drugs to Avoid with CMT
— high IV doses Phenytoin Podophyllin resin Sertraline (Zoloft) Statins Tumor necrosis factor-a Zimeldine* a-Interferon Negligible or doubtful risk Allopurinol Amitriptyline Chloramphenicol Chlorprothixene Cimetidine Clioquinil Clofibrate Enalapril Fluoroquinolones Gabapentin Gluthethimide Lithium
Phenelzine
— high IV doses Phenytoin Podophyllin resin Sertraline (Zoloft) Statins Tumor necrosis factor-a Zimeldine* a-Interferon Negligible or doubtful risk Allopurinol Amitriptyline Chloramphenicol Chlorprothixene Cimetidine Clioquinil Clofibrate Enalapril Fluoroquinolones Gabapentin Gluthethimide Lithium
Phenelzine
Hidden
in
Charcot-Marie-Tooth UK
7 years ago
1 anxiety leads to the next, & always some depression
The single medicine for anxiety and anxiety physical effects is
Phenelzine
, it the gold standard. Its around for ages but the downside is its selectivity. At low dose you have GABA, Serotonin, Dopamine working unfortunately it also starts to hit the Noradrenaline receptors.
The single medicine for anxiety and anxiety physical effects is
Phenelzine
, it the gold standard. Its around for ages but the downside is its selectivity. At low dose you have GABA, Serotonin, Dopamine working unfortunately it also starts to hit the Noradrenaline receptors.
Hidden
in
Anxiety Support
9 years ago
So fed up
Does anyone know how long I would have to wait for
phenelzine
to take effect and work if it is going to? Cpn and doctor say completely different things. I am so fed up with everything now. Sorry.
Does anyone know how long I would have to wait for
phenelzine
to take effect and work if it is going to? Cpn and doctor say completely different things. I am so fed up with everything now. Sorry.
Bandboxarnie
in
Mental Health Support
10 years ago
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