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Sage Therapeutics scraps Parkinson's drug development after treatment fails mid-stage study
https://www.xm.com/research/markets/allNews/reuters/sage-therapeutics-scraps-parkinsons-drug-development-after-treatment-fails-midstage-study-53814940
https://www.xm.com/research/markets/allNews/reuters/sage-therapeutics-scraps-parkinsons-drug-development-after-treatment-fails-midstage-study-53814940
Farooqji
in
Cure Parkinson's
2 months ago
night time pains
I have posted a number of times about night time pain …which I am still getting! However by taking an enema each morning when waking I get rid of the wind and normally have a bowel movement and can have a good day. However at night when going to bed I get wind and two hours later I am awake. I get
I have posted a number of times about night time pain …which I am still getting! However by taking an enema each morning when waking I get rid of the wind and normally have a bowel movement and can have a good day. However at night when going to bed I get wind and two hours later I am awake. I get
Reindeer1
in
IBS Network
2 months ago
Side Effects of Hydrea?
Ho everyone, I had a stroke last year which led to them discovering that I am Jak2 positive. I was initial put onto Pegasus, but that had horrendous side effects and was then put onto Hydrea. Almost since first getting put onto Hydrea, there have been a bunch of different things that I feel can
Ho everyone, I had a stroke last year which led to them discovering that I am Jak2 positive. I was initial put onto Pegasus, but that had horrendous side effects and was then put onto Hydrea. Almost since first getting put onto Hydrea, there have been a bunch of different things that I feel can
TyronR
in
MPN Voice
2 months ago
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onset of symptoms after shot
Hi All, Does anyone experience quick onset of symptoms after injecting? My feet and hands go numb and I get dizzy and nauseous. Sometimes I get arm twitching floaters in my eyes dry eyes and mouth and feels like I’m going to faint . The symptoms do pass after awhile but it definitely is happening after
Hi All, Does anyone experience quick onset of symptoms after injecting? My feet and hands go numb and I get dizzy and nauseous. Sometimes I get arm twitching floaters in my eyes dry eyes and mouth and feels like I’m going to faint . The symptoms do pass after awhile but it definitely is happening after
Jjjmmm
in
Pernicious Anaemia Society
2 months ago
A few questions about being a. ‘Glaucoma suspect’
Hi, first post for me. I’ve been reading your messages since February and they have been very helpful so thank you all!! This is the rather longwinded background: My husband was picked up at a routine eye test as having some changes suggestive of glaucoma. He was seen pretty quickly (within 2-3 weeks
Hi, first post for me. I’ve been reading your messages since February and they have been very helpful so thank you all!! This is the rather longwinded background: My husband was picked up at a routine eye test as having some changes suggestive of glaucoma. He was seen pretty quickly (within 2-3 weeks
NCFCfan
in
Glaucoma UK
2 months ago
Somebody asked why I take Berberine. I figured it something good to share.
Yeah, I need to write down why I take things (I forget why eventually).
So Berberine:
1: It suppresses viruses, including EBV. I think viruses may play some role in PD (I have not been diagnosed with PD. I have RBD and a sore shoulder and some other troubling symptoms): https://healthunlocked.com
Yeah, I need to write down why I take things (I forget why eventually).
So Berberine:
1: It suppresses viruses, including EBV. I think viruses may play some role in PD (I have not been diagnosed with PD. I have RBD and a sore shoulder and some other troubling symptoms): https://healthunlocked.com
Bolt_Upright
in
Cure Parkinson's
2 months ago
Iodine and Povidone - A Chemistry Lesson
Over the years, we have seen many mentions of povidone-iodine. This video is the first time I have ever come across a proper explanation as to why povidone-iodine is chosen! It then continues with its aim of extracting pure iodine from povidone-iodine. The video could be very boring if you are
Over the years, we have seen many mentions of povidone-iodine. This video is the first time I have ever come across a proper explanation as to why povidone-iodine is chosen! It then continues with its aim of extracting pure iodine from povidone-iodine. The video could be very boring if you are
helvella
Thyroid UK
in
Thyroid UK
2 months ago
Diabetic numbers
Hi, I know this is a Thyroid sight , but j just joined the Diabetes forum anx I can't seem to post on there . What are these diabetes numbers please anyone , normal = 42 - 47 and pre- diabetes = 48
Hi, I know this is a Thyroid sight , but j just joined the Diabetes forum anx I can't seem to post on there . What are these diabetes numbers please anyone , normal = 42 - 47 and pre- diabetes = 48
Goldengirl69
in
Thyroid UK
2 months ago
negative pressure in both ears
Hello everyone Has anyone been diagnosed with negative pressure in their ears? I had an appointment with the audiologist recently and she said I had negative pressure in both my ears. I have hearing loss in both ears and tinnitus in my left ear, sometimes in my right ear. I am waiting to be fitted
Hello everyone Has anyone been diagnosed with negative pressure in their ears? I had an appointment with the audiologist recently and she said I had negative pressure in both my ears. I have hearing loss in both ears and tinnitus in my left ear, sometimes in my right ear. I am waiting to be fitted
Choralmusic
in
Tinnitus UK
2 months ago
tinnitus - get your hearing aids insured!!
while out on a regular five mile hill walk two weeks ago high up on the Quantocks, with the weather windy and cold then warmer and still, my hat was on and off every ten mins. By the time I reached the car I noticed that one of the aids was no longer there. It’s wasnt in the scarf, down my top or in
while out on a regular five mile hill walk two weeks ago high up on the Quantocks, with the weather windy and cold then warmer and still, my hat was on and off every ten mins. By the time I reached the car I noticed that one of the aids was no longer there. It’s wasnt in the scarf, down my top or in
Bridiecat
in
Tinnitus UK
2 months ago
CLL - Leukemia Cutis
Hello everyone. CLL Dx 2002, unmutated, Trisomy12, Notch 1. O+I 2 years, Off meds 2 years (heart surgery), WBC has been slowly rising ove4r the past 4 or 5 months, but I was never at MRD. A biopsy of a "rash" on my scalp shows Leukemia Cutis - most likely CLL related. Has anyone else had this? How
Hello everyone. CLL Dx 2002, unmutated, Trisomy12, Notch 1. O+I 2 years, Off meds 2 years (heart surgery), WBC has been slowly rising ove4r the past 4 or 5 months, but I was never at MRD. A biopsy of a "rash" on my scalp shows Leukemia Cutis - most likely CLL related. Has anyone else had this? How
misterbee
in
CLL Support
2 months ago
mucus
Hi, I've had mucus in my inner ear for around 7 years which causes tinnitus,I can keep cracking it by yawning but makes the tinnitus even louder, been to doctors had MRI scan but can't do anything and don't seem that interested,I was wondering if I burst my ear drum it would let the fluid out or would
Hi, I've had mucus in my inner ear for around 7 years which causes tinnitus,I can keep cracking it by yawning but makes the tinnitus even louder, been to doctors had MRI scan but can't do anything and don't seem that interested,I was wondering if I burst my ear drum it would let the fluid out or would
Manmax
in
Tinnitus UK
2 months ago
bladder aches
Hello all! New to the forum, 42 years old, male. Thanks for having me! About eight months ago, and for the first time in my life, I suddenly developed an ache in my bladder area. I had a prostate exam and blood test, as well as a UTI test and all was negative. Within 2-3 weeks the pain went away
Hello all! New to the forum, 42 years old, male. Thanks for having me! About eight months ago, and for the first time in my life, I suddenly developed an ache in my bladder area. I had a prostate exam and blood test, as well as a UTI test and all was negative. Within 2-3 weeks the pain went away
GaryABul
in
Bladder Health UK
2 months ago
I'm depressed please help me
I have abdominal pain gas with constipation before 9 months ago, then I do a sonography and a endoscopy, endoscopy report was normal but I had a gallbladder stone ,11 mm .I removed my gallbladder. After surgery I have mild constipation and diarrhea, mild abdominal pain and gas problem.I had my surgery
I have abdominal pain gas with constipation before 9 months ago, then I do a sonography and a endoscopy, endoscopy report was normal but I had a gallbladder stone ,11 mm .I removed my gallbladder. After surgery I have mild constipation and diarrhea, mild abdominal pain and gas problem.I had my surgery
Namkia
in
Colon Cancer Connected
1 year ago
Tinnitus
I wonder if anyone else is suffering from tinnitus. I have noticed my tinnitus is getting worse and was reading up on it. So it seems it can affect people with auto immune diseases. I am taking 20mg methotrexate each week and these drugs are known to increase symptoms of tinnitus. Does anyone else have
I wonder if anyone else is suffering from tinnitus. I have noticed my tinnitus is getting worse and was reading up on it. So it seems it can affect people with auto immune diseases. I am taking 20mg methotrexate each week and these drugs are known to increase symptoms of tinnitus. Does anyone else have
LuckyLucy007
in
Scleroderma & Raynaud's UK (SRUK)
2 months ago
High platelet count due to iron deficiency anaemia maybe?
Just again when I thought all was going well ! High platelet count from recent blood test shows Platelet count 515 10*9/L Platelet count has been abnormal for some time, but never this high. Not sure whether I should request the ferrous sulphate again, OR could it be PMR flare. I have felt pretty
Just again when I thought all was going well ! High platelet count from recent blood test shows Platelet count 515 10*9/L Platelet count has been abnormal for some time, but never this high. Not sure whether I should request the ferrous sulphate again, OR could it be PMR flare. I have felt pretty
gillsky8
in
PMRGCAuk
2 months ago
IBS and Methane Gas
I have had stomach problems for the last 20 years but they seem to have gotten much worse. I'm 75 and there's not a day that goes by that I don't think about how bad my stomach feels...bloating, pain, full after eating a little bit and pain. It seems like it's constant. I also have a colon full of
I have had stomach problems for the last 20 years but they seem to have gotten much worse. I'm 75 and there's not a day that goes by that I don't think about how bad my stomach feels...bloating, pain, full after eating a little bit and pain. It seems like it's constant. I also have a colon full of
Carsok
in
IBS Network
1 year ago
Deal on PROTACs: ARV-766 development will be carried out by Novartis
in a nutshell, a PROTAC (PROteolysis TArgeting Chimera) is like a specialized tool designed to eliminate unwanted proteins in the body. It's like a magic marker that marks a specific protein inside a cell (cancer cell in our case). This tricks the internal "waste management system" of into breaking down
in a nutshell, a PROTAC (PROteolysis TArgeting Chimera) is like a specialized tool designed to eliminate unwanted proteins in the body. It's like a magic marker that marks a specific protein inside a cell (cancer cell in our case). This tricks the internal "waste management system" of into breaking down
Maxone73
in
Advanced Prostate Cancer
2 months ago
Thank you
I just wanted to thank everyone who took the time to reply to my previous post about my balance issues. It was very overwhelming having so many replies and as i work a 12 hour shift and have brain fog and my concentration is non existant it's taken me this long to read all the replies. I had my drs
I just wanted to thank everyone who took the time to reply to my previous post about my balance issues. It was very overwhelming having so many replies and as i work a 12 hour shift and have brain fog and my concentration is non existant it's taken me this long to read all the replies. I had my drs
catpurple7
in
Thyroid UK
2 months ago
Suspect I have Addison's
I had a blood test yesterday and my serum cortisol was 330 nm/l.I have some hyperpigmentation & vitaligo. I think my GP was checking for Addison's. Hopefully now I can see an endocrinologist
I had a blood test yesterday and my serum cortisol was 330 nm/l.I have some hyperpigmentation & vitaligo. I think my GP was checking for Addison's. Hopefully now I can see an endocrinologist
antiloquax
in
Thyroid UK
2 months ago
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