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Current advances of liquid biopsies in prostate cancer: Molecular biomarkers, Cell/Molecular Therapy Oncolytics, 09/21/23
Recent comprehensive paper on the use of liquid biopsies for diagnosis and treatment of PCa. Comprehensive summary tables are provided for both purposes. From the paper: [i]Introduction[/i] [i]The prostate-specific antigen (PSA) test is one of the most widely used screening tests for men at risk for
Recent comprehensive paper on the use of liquid biopsies for diagnosis and treatment of PCa. Comprehensive summary tables are provided for both purposes. From the paper: [i]Introduction[/i] [i]The prostate-specific antigen (PSA) test is one of the most widely used screening tests for men at risk for
CaptnMojoe
in
Fight Prostate Cancer
7 months ago
Provenge Underway
Morning folks, Well I completed my first cycle of Provenge yesterday and all seems well so far. I also met with MO to review recent genetic testing results and have confirmed a mutation BRiP1 which is associated with autosomal dominant hereditary ovarian cancer, autosomal recessive Fanconia anemia,
Morning folks, Well I completed my first cycle of Provenge yesterday and all seems well so far. I also met with MO to review recent genetic testing results and have confirmed a mutation BRiP1 which is associated with autosomal dominant hereditary ovarian cancer, autosomal recessive Fanconia anemia,
Pmann
in
Advanced Prostate Cancer
7 months ago
Could PSA of 3.0 be a problem?
My 48 year old son lives in Norway. He was recently contacted by their hereditary cancer clinic and advised that his PSA had increased to 3.0 from from last years 2.5. They felt that's a little high for his age and are going to call him in for an MR and a new PSA test. Is this any cause for concern
My 48 year old son lives in Norway. He was recently contacted by their hereditary cancer clinic and advised that his PSA had increased to 3.0 from from last years 2.5. They felt that's a little high for his age and are going to call him in for an MR and a new PSA test. Is this any cause for concern
Hidden
in
Prostate Cancer Network
9 months ago
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BP with abiraterone + prednisone, eplerenone, dexamethasone
I have been on Lupron and abiraterone with (initially) prednisone for 4.5 years, which has maintained my PSA at <0.1 since 111 at diagnosis. I have all the usual side effects. One that doesn't bother me day-to-day, but definitely concerns me, is hypertension. Before PCa, I had moderately high BP, which
I have been on Lupron and abiraterone with (initially) prednisone for 4.5 years, which has maintained my PSA at <0.1 since 111 at diagnosis. I have all the usual side effects. One that doesn't bother me day-to-day, but definitely concerns me, is hypertension. Before PCa, I had moderately high BP, which
Gearhead
in
Advanced Prostate Cancer
9 months ago
Declining psa #5
Gm ladies n gentlemen, after a stabilization psa between 1.5-1.7 for the last two months solely on ivermectin, I incorporated cbd, turmeric, zinc a lot of fruits especially cherries š and the pits (2-5 daily) of cherries, peaches, plums n apricots for the natural amygdalin nutrient and I am happy to
Gm ladies n gentlemen, after a stabilization psa between 1.5-1.7 for the last two months solely on ivermectin, I incorporated cbd, turmeric, zinc a lot of fruits especially cherries š and the pits (2-5 daily) of cherries, peaches, plums n apricots for the natural amygdalin nutrient and I am happy to
Nfler
in
Advanced Prostate Cancer
9 months ago
Rickyfish56 "Introduction"
Reviewed my "Bio" and it said I needed to "introduce" myself? Mostly just read postings and try to gather information. But, here is my " introduction", family history of Prostate cancer, Dad diagnosed at 59, removed prostate old fashion slice and dice, never regained any sexual function, but alive today
Reviewed my "Bio" and it said I needed to "introduce" myself? Mostly just read postings and try to gather information. But, here is my " introduction", family history of Prostate cancer, Dad diagnosed at 59, removed prostate old fashion slice and dice, never regained any sexual function, but alive today
rickyfish56
in
Advanced Prostate Cancer
5 months ago
ADT before Surgery?
I have a prostatectomy which is probably 6-8 weeks in my future. My outlook is that metastasis in imminent. (T3bM0n0 and no evidence of cancer outside the gland as of May 25 PSMA PET scan, but I am told I am intermediate/unfavorable and my PSA went from 10 to 12 in only a month.) Today is August 18.
I have a prostatectomy which is probably 6-8 weeks in my future. My outlook is that metastasis in imminent. (T3bM0n0 and no evidence of cancer outside the gland as of May 25 PSMA PET scan, but I am told I am intermediate/unfavorable and my PSA went from 10 to 12 in only a month.) Today is August 18.
Lost_Sheep
in
Prostate Cancer Network
9 months ago
Blood in urine and clotting 3 weeks after starting Zytiga
After starting Zytiga I noticed a few drops of blood but only after a bowel motion. Yesterday after a big bowel motion I couldnāt pee and headed for hospital though on getting there I suppose my bladder was full enough it forced the clot out while going to the toilet. Iāve had blockage problems ana
After starting Zytiga I noticed a few drops of blood but only after a bowel motion. Yesterday after a big bowel motion I couldnāt pee and headed for hospital though on getting there I suppose my bladder was full enough it forced the clot out while going to the toilet. Iāve had blockage problems ana
Ausi
in
Advanced Prostate Cancer
9 months ago
FYI: New data on progression of visceral mets without PSA progression (discordance) and ARAT/docetaxel therapy
Interesting study, folks. We know physical progression of PCa (i.e., new metastases) can occur without PSA progression. This is known as a discordance. But we don't know how often it occurs or why it occurs. In these instances, our greatest fear is "therapy-induced neuroendocrine prostate cancer
Interesting study, folks. We know physical progression of PCa (i.e., new metastases) can occur without PSA progression. This is known as a discordance. But we don't know how often it occurs or why it occurs. In these instances, our greatest fear is "therapy-induced neuroendocrine prostate cancer
SeosamhM
in
Advanced Prostate Cancer
9 months ago
Newly detectable PSA after prostatectomy: RT + ADT planned; add Erleada?
Diagnosed 12/21, PSA 7, negative PSMA PET. Radical prostatectomy with extended lymph node dissection in Mar 2022. Gleason 4+5, +cribriform, +intraductal, + bilat SVI, +ECE. Margins negative (barely) and 1/34 lymph nodes positive with very small focus of cancer. PSA was undetectable until Jun 2023, then
Diagnosed 12/21, PSA 7, negative PSMA PET. Radical prostatectomy with extended lymph node dissection in Mar 2022. Gleason 4+5, +cribriform, +intraductal, + bilat SVI, +ECE. Margins negative (barely) and 1/34 lymph nodes positive with very small focus of cancer. PSA was undetectable until Jun 2023, then
Brokedown_Palace
in
Advanced Prostate Cancer
9 months ago
My PSA tripled in 8 months
I had my RP in Jan 31, 2023, started hormonal therapy from April 17 with Diphereline every 28 days plus one Casodex daily. My PSA went down to 0.005 from May to November. Yesterday I had my blood test again and the report indicated my PSA has jumped to 0.159. I am panic. Can you explain what does
I had my RP in Jan 31, 2023, started hormonal therapy from April 17 with Diphereline every 28 days plus one Casodex daily. My PSA went down to 0.005 from May to November. Yesterday I had my blood test again and the report indicated my PSA has jumped to 0.159. I am panic. Can you explain what does
Formosan
in
Advanced Prostate Cancer
5 months ago
Brain metastasis
New (Portuguese) anecdotal case study below. [1] When I began reading PCa studies on PubMed, I saw a lot of cell studies that used LNCaP (from a lymph PCa cell), PC3 (from a bone PCa cell) &/or DU145 (supposedly a brain met cell, but now described as "derived from a central nervous system metastasis
New (Portuguese) anecdotal case study below. [1] When I began reading PCa studies on PubMed, I saw a lot of cell studies that used LNCaP (from a lymph PCa cell), PC3 (from a bone PCa cell) &/or DU145 (supposedly a brain met cell, but now described as "derived from a central nervous system metastasis
pca2004
in
Fight Prostate Cancer
9 months ago
AUA 2023: PSA Response and Time-to-Castration Resistance Among Patients with mCSPCa Initiated on Apalutamide, Enzalutamide, or Abiraterone
The objective of this study was to describe a āreal-worldā experience of mCSPC patients treated with apalutamide, enzalutamide, and abiraterone acetate, with a focus on PSA response and development of castration resistance outcomes. This study identified patients with mCSPC newly initiated on apalutamide
The objective of this study was to describe a āreal-worldā experience of mCSPC patients treated with apalutamide, enzalutamide, and abiraterone acetate, with a focus on PSA response and development of castration resistance outcomes. This study identified patients with mCSPC newly initiated on apalutamide
skiingfiend
in
Advanced Prostate Cancer
9 months ago
Welcome to Stage Denial
Greetings, fellow warriors fighting prostate cancer. Mababa here, with a funny-sounding username that's a joining of my first name initial with the last part of the name of the city where I was born: Addis Ababa, seventy-one years and six months ago. Actually, I'm not quite in the fight yet, so I can't
Greetings, fellow warriors fighting prostate cancer. Mababa here, with a funny-sounding username that's a joining of my first name initial with the last part of the name of the city where I was born: Addis Ababa, seventy-one years and six months ago. Actually, I'm not quite in the fight yet, so I can't
mababa
in
Advanced Prostate Cancer
5 months ago
Abiraterone and food
My husband has been on Abiraterone for 2 months, during which time his PSA has doubled. Iāve recently read posts about the advantages of taking Abiraterone with food instead of taking it an hour before eating as recommended. The posts are quite old (5 years) - is taking Abi with food still a consideration
My husband has been on Abiraterone for 2 months, during which time his PSA has doubled. Iāve recently read posts about the advantages of taking Abiraterone with food instead of taking it an hour before eating as recommended. The posts are quite old (5 years) - is taking Abi with food still a consideration
NLondon43
in
Advanced Prostate Cancer
9 months ago
Positive results, Pluvicto
Iām at Mayo for my third Pluvicto (Lutetium-177) treatment. Yesterday, I had a PSMA Pet scan to check on progress. Iām happy to report that itās all positive at this point in the game. I include below the āfindingsā on the radiology report from the scan which speaks for itself. I look forward to hearing
Iām at Mayo for my third Pluvicto (Lutetium-177) treatment. Yesterday, I had a PSMA Pet scan to check on progress. Iām happy to report that itās all positive at this point in the game. I include below the āfindingsā on the radiology report from the scan which speaks for itself. I look forward to hearing
Skifanatic
in
Advanced Prostate Cancer
9 months ago
PSA Bounce after radiation
Has anyone experienced a PSA rise after SBRT for bone metastasis? If so, would like to hear your story. Thanks.
Has anyone experienced a PSA rise after SBRT for bone metastasis? If so, would like to hear your story. Thanks.
NDJIM
in
Advanced Prostate Cancer
9 months ago
Rapidly Rising PSA
As some of you know, I am now under the care of two excellent oncologists, including Prof. De Bono at Royal Marsden Cancer Centre. I was originally deemed to have a non-aggressive cancer (in 14 years my PSA has never exceeded 4.1) However, over the last 6 weeks (when I have been on no treatment whatsoever
As some of you know, I am now under the care of two excellent oncologists, including Prof. De Bono at Royal Marsden Cancer Centre. I was originally deemed to have a non-aggressive cancer (in 14 years my PSA has never exceeded 4.1) However, over the last 6 weeks (when I have been on no treatment whatsoever
CrocodileShoes
in
Advanced Prostate Cancer
9 months ago
PSA drop after ADT
My PSA went from 14.9 ug/l in May to 5.9 ug/l in June to 0.24 ug/l when tested 2 days ago after Lupron injection 3 months ago. Naturally I'm very relieved over the drop.My oncologist has pretty much left the decision to me on the ADT duration. I had earlier voiced my reservation about ADT on account
My PSA went from 14.9 ug/l in May to 5.9 ug/l in June to 0.24 ug/l when tested 2 days ago after Lupron injection 3 months ago. Naturally I'm very relieved over the drop.My oncologist has pretty much left the decision to me on the ADT duration. I had earlier voiced my reservation about ADT on account
John347
in
Advanced Prostate Cancer
9 months ago
And on it goesā¦..
My Joe had his first ambulance ride yesterday. Despite all our communication with the anesthesiologist prior to a minor elbow surgery, he was laid flat on his back for the procedure. When he ācrashedā as the surgery ended, they sat him up, gave him two breathing treatments and decided to transport him
My Joe had his first ambulance ride yesterday. Despite all our communication with the anesthesiologist prior to a minor elbow surgery, he was laid flat on his back for the procedure. When he ācrashedā as the surgery ended, they sat him up, gave him two breathing treatments and decided to transport him
Cateydid
in
Advanced Prostate Cancer
9 months ago
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