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PSA Response From Broccoli Sprout Extract (Sulforaphane) May Due To Just Being Moderate ADT
I forgot I ran across this a 2 years ago as many with PCa diagnosis are very interested in Sulforaphane due to a lot of excitement from a few studies a few years ago. (This fueled an explosion of supplements on Amazon.) This however is one of the more expensive supplements and my jury is still out
I forgot I ran across this a 2 years ago as many with PCa diagnosis are very interested in Sulforaphane due to a lot of excitement from a few studies a few years ago. (This fueled an explosion of supplements on Amazon.) This however is one of the more expensive supplements and my jury is still out
jazj
in
Advanced Prostate Cancer
5 months ago
Declining psa #9
Gm folks, hope all are having a wonderful New Year. I’m following up n giving results on using ivermectin, cbd oil, turmeric Vit b3,6,12 Vit c And zinc solely after eliminating ADT after 7 months, post Rp n rad… Psa dropped another .29 points to .66 down from .95 n psa was hovering 7 when I first got
Gm folks, hope all are having a wonderful New Year. I’m following up n giving results on using ivermectin, cbd oil, turmeric Vit b3,6,12 Vit c And zinc solely after eliminating ADT after 7 months, post Rp n rad… Psa dropped another .29 points to .66 down from .95 n psa was hovering 7 when I first got
Nfler
in
Advanced Prostate Cancer
5 months ago
AMG 509 (Xaluritamig): update on this immunotherapy for mCRPC
They published the first findings on Cancer Discovery. "Efficacy as measured both by PSA and objective response by RECIST were encouraging in this heavily pretreated mCRPC population, and responses occurred with greater frequency in the higher-dose cohorts. PSA declines were seen starting with 0.1 mg
They published the first findings on Cancer Discovery. "Efficacy as measured both by PSA and objective response by RECIST were encouraging in this heavily pretreated mCRPC population, and responses occurred with greater frequency in the higher-dose cohorts. PSA declines were seen starting with 0.1 mg
Maxone73
in
Advanced Prostate Cancer
5 months ago
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High-Dose Vitamin B1 / Thiamine and Fat Soluble Benfotiamine Form
I am reposting a reply to the Vitamin B1 thread as I noticed a search on HealthUnlocked for Benfotiamine doesn't list the thread for Vitamin B1 and the information I posted doesn't fit in one reply. I'm not giving medical advice but I know a lot of people here are open to trying things and watch if
I am reposting a reply to the Vitamin B1 thread as I noticed a search on HealthUnlocked for Benfotiamine doesn't list the thread for Vitamin B1 and the information I posted doesn't fit in one reply. I'm not giving medical advice but I know a lot of people here are open to trying things and watch if
jazj
in
Advanced Prostate Cancer
5 months ago
Which Treatment for These Biopsy Results?
I now have my biopsy results Gleason 3 + 4 ie 90% of 3 and 10% of 4 Grade 2 The consultant said it was Intermediate but at one point used the term Low intermediate. Is this latter term valid given the stats? T2a NO MO - but I am puzzled about this because although it was mostly all on the left side
I now have my biopsy results Gleason 3 + 4 ie 90% of 3 and 10% of 4 Grade 2 The consultant said it was Intermediate but at one point used the term Low intermediate. Is this latter term valid given the stats? T2a NO MO - but I am puzzled about this because although it was mostly all on the left side
Nordman
in
Advanced Prostate Cancer
5 months ago
SRBT and EXTEND trial
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Purple-Bike
in
Advanced Prostate Cancer
5 months ago
What is the next step
I have one more Immunotherapy for my bladder cancer, so far all scan have shown no metastasis. Now I need to focus on my PC after more than a year of ignoring it. My PSA has been fluctuating and is now 0.65, doubling time is 16 months, I have not had ADT yet and my MO wants to just wait and watch. What
I have one more Immunotherapy for my bladder cancer, so far all scan have shown no metastasis. Now I need to focus on my PC after more than a year of ignoring it. My PSA has been fluctuating and is now 0.65, doubling time is 16 months, I have not had ADT yet and my MO wants to just wait and watch. What
old64horn
in
Advanced Prostate Cancer
5 months ago
CDK 12 mutation and Immunotherapy
Hi All, My PSA as is starting to rise on Arbi/Dexa. I have the CDK12 mutation which is apparently known to be a drug target or to predict sensitivity to Atezolizumab (Tecentriq PD-1 Checkpoint Inhibitor), hence there is open Immunotherapy trial called BoB (NCT03767075). I meet the trial doctor next
Hi All, My PSA as is starting to rise on Arbi/Dexa. I have the CDK12 mutation which is apparently known to be a drug target or to predict sensitivity to Atezolizumab (Tecentriq PD-1 Checkpoint Inhibitor), hence there is open Immunotherapy trial called BoB (NCT03767075). I meet the trial doctor next
MikeMartin
in
Advanced Prostate Cancer
5 months ago
Erectile dysfunction
Hi My first post, I think it is pretty obvious that many of us, me included, associate our self worth, status with our 'masculinity'. This may or may not be a good thing, but many, most men in fact consider themselves to be profoundly binary. They represent the '1' to a feminine '0'. When a man fails
Hi My first post, I think it is pretty obvious that many of us, me included, associate our self worth, status with our 'masculinity'. This may or may not be a good thing, but many, most men in fact consider themselves to be profoundly binary. They represent the '1' to a feminine '0'. When a man fails
Iro1
in
Sensitive Issues for Men
5 months ago
Is there any order to when new medications or PARP inhibitor are tried?
My medical oncologist is hell bent on me doing Lu 177 pluvicto next, I was hoping to try other things first… Medical Oncologist suggested waiting for the next two months to see if PSA is still rising…and to do a pet scan Diagnosed 06/2022 Gleason 8/9 Oligo metastatic 3 lytic lesions two resolved
My medical oncologist is hell bent on me doing Lu 177 pluvicto next, I was hoping to try other things first… Medical Oncologist suggested waiting for the next two months to see if PSA is still rising…and to do a pet scan Diagnosed 06/2022 Gleason 8/9 Oligo metastatic 3 lytic lesions two resolved
Shorehousejam
in
Fight Prostate Cancer
5 months ago
Question, each month with rising PSA, when do I do a pet scan
Medical Oncologist suggested waiting for the next two months to see if it’s still rising… Diagnosed 06/2022 Gleason 8/9 Oligo metastatic 3 lytic lesions two resolved Started Firmagon 7/6/2022 Zytiga with Prednisone 7/20/2022 currently still on these meds Docetaxel Chemotherapy on 08/11/2022
Medical Oncologist suggested waiting for the next two months to see if it’s still rising… Diagnosed 06/2022 Gleason 8/9 Oligo metastatic 3 lytic lesions two resolved Started Firmagon 7/6/2022 Zytiga with Prednisone 7/20/2022 currently still on these meds Docetaxel Chemotherapy on 08/11/2022
Shorehousejam
in
Advanced Prostate Cancer
5 months ago
Post SBRT Day 9 - 15
Continuing my reporting on my experience after 5 SBRT treatments with focal boost, Barrigel spacer, urethral steering to try and avoid GU side effects. I am 68, in good shape, one 4+3, one 3+3, Decipher .84, PSA 7.8, PSMA PET confined to prostate, 6 months Orgovyx. Flomax started with treatment and
Continuing my reporting on my experience after 5 SBRT treatments with focal boost, Barrigel spacer, urethral steering to try and avoid GU side effects. I am 68, in good shape, one 4+3, one 3+3, Decipher .84, PSA 7.8, PSMA PET confined to prostate, 6 months Orgovyx. Flomax started with treatment and
ToolBeltZia
in
Prostate Cancer Network
5 months ago
Letting Go
If it is one thing that I have after almost 18 years of playing this game, it is a story or perhaps many stories. So Many chapters. What I am about to say may seem easy from the perspective of undetectable PSA and clear scans these past 10 years. I assure you that at the time there was nothing easy about
If it is one thing that I have after almost 18 years of playing this game, it is a story or perhaps many stories. So Many chapters. What I am about to say may seem easy from the perspective of undetectable PSA and clear scans these past 10 years. I assure you that at the time there was nothing easy about
Todd1963
in
Advanced Prostate Cancer
5 months ago
Concern - At 4 mo on Lupron/Abi, Testosterone hits 40
While PSA was again <.1 yesterday, testosterone jumped to 40 ng/dl or 1.4 nmole/L, which is a big move toward the 1.7 danger zone for faster movement toward CRPC ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472467/ ) , and I am interested
While PSA was again <.1 yesterday, testosterone jumped to 40 ng/dl or 1.4 nmole/L, which is a big move toward the 1.7 danger zone for faster movement toward CRPC ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472467/ ) , and I am interested
jackwfrench
in
Advanced Prostate Cancer
5 months ago
RT results look good
After a bout of sepsis from a directed biopsy, 5 weeks of RT and 3 months of Eligard, my tests show undetectable PSA. I'm still dealing with side effects (interrupted sleep, urinary and bowel differences) but happy to report it looks like, for the time being, that my stage 2/3 PC may have been beaten
After a bout of sepsis from a directed biopsy, 5 weeks of RT and 3 months of Eligard, my tests show undetectable PSA. I'm still dealing with side effects (interrupted sleep, urinary and bowel differences) but happy to report it looks like, for the time being, that my stage 2/3 PC may have been beaten
Eadgbe
in
Fight Prostate Cancer
5 months ago
PSA 6 months after RT
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
janebob99
in
Prostate Cancer Network
5 months ago
LIQUID BIOPSY: Hello friends, what do you know about Liquid biopsy of circulating tumor ctDNA? Is it usefull with 6.2 PSA ?
Hello friends, what do you know about Liquid biopsy of circulating tumor ctDNA? Is it usefull with 6.2 PSA ? Depending on the results do we get access to some novel drugs like olapariv or nivolumab, etc, that might help us ? 🫠thanks, Manilo.
Hello friends, what do you know about Liquid biopsy of circulating tumor ctDNA? Is it usefull with 6.2 PSA ? Depending on the results do we get access to some novel drugs like olapariv or nivolumab, etc, that might help us ? 🫠thanks, Manilo.
Manilo
in
Advanced Prostate Cancer
5 months ago
Update on my father
Dad was diagnosed in 2016 stage 4, bones and lymphnodes. We dont have a gleason score because his diagnoses was found through a hip xray after a fall and they biopsied his hip. He has had lupron, xgeva, bicalutamide and now he is on Xtandi. Dads last bone scan psa were July 8th. His bone scan showed
Dad was diagnosed in 2016 stage 4, bones and lymphnodes. We dont have a gleason score because his diagnoses was found through a hip xray after a fall and they biopsied his hip. He has had lupron, xgeva, bicalutamide and now he is on Xtandi. Dads last bone scan psa were July 8th. His bone scan showed
Radtech40
in
Advanced Prostate Cancer
5 months ago
Testosterone was nearly back to normal, then dropped
I had a year of Lupron and Enzalutamide in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal? I had 6 months of ADT in connection with radiation for recurrent PCa
I had a year of Lupron and Enzalutamide in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal? I had 6 months of ADT in connection with radiation for recurrent PCa
Teddy28
in
Advanced Prostate Cancer
5 months ago
Discontinue all antioxidant supplements on early signs of biochemical recurrence?
The latest literature appears to indicate a PSA as low as 0.03, regardless of the multi-result dynamics is a reliable very early confirmation of biochemical recurrence. Maybe it's arguable some rare cases may "slip through" and stabilize without further treatment but data from the latest studies is
The latest literature appears to indicate a PSA as low as 0.03, regardless of the multi-result dynamics is a reliable very early confirmation of biochemical recurrence. Maybe it's arguable some rare cases may "slip through" and stabilize without further treatment but data from the latest studies is
jazj
in
Advanced Prostate Cancer
5 months ago
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