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Know your Biomarker … Know Your Mutation
KRAS mutation in colorectal cancer is an abnormal change in the KRAS gene, which is involved in controlling cell growth and survival. 40% of CRC has a KRAS mutation. There are more than 25 ongoing clinical trials studying treatments for KRAS-mutated colorectal cancer. Learn more about the KRAS biomarker
KRAS mutation in colorectal cancer is an abnormal change in the KRAS gene, which is involved in controlling cell growth and survival. 40% of CRC has a KRAS mutation. There are more than 25 ongoing clinical trials studying treatments for KRAS-mutated colorectal cancer. Learn more about the KRAS biomarker
GCCA-Survivor
Administrator
in
Colon Cancer Connected
4 months ago
AFib and Blood Pressure
Is there a correlation or causation or no link between Afib and high blood pressure? I had sudden occurrence of persistent AF and high BP. My BP had always been well within the normal range. Thank you for any info you can provide. I know it will be thoughtful and I understand you are not physicians
Is there a correlation or causation or no link between Afib and high blood pressure? I had sudden occurrence of persistent AF and high BP. My BP had always been well within the normal range. Thank you for any info you can provide. I know it will be thoughtful and I understand you are not physicians
Cholla3
in
AF Association
10 months ago
Too much to take in!
A lot going on with no answers. Firstly having been diagnosed with AF in May, I had my fourth episode whilst in France a couple of weeks ago. Previous to that I was asked whether I would take part in the DOCCLA system which is an extension of a hospital ward apparently where they monitor you at home
A lot going on with no answers. Firstly having been diagnosed with AF in May, I had my fourth episode whilst in France a couple of weeks ago. Previous to that I was asked whether I would take part in the DOCCLA system which is an extension of a hospital ward apparently where they monitor you at home
Retired010
in
AF Association
10 months ago
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Multi-Drug Combo May Be Best Against Prostate Cancer...I thought it was a known fact already!
"Combining two or three testosterone-blocking drugs prevents the spread of prostate cancer better than just a single medication, a new clinical trial has found." Dr Aggrawal again! https://www.usnews.com/news/health-news/articles/2024-01-25/multi-drug-combo-may-be-best-against-prostate-cancer
"Combining two or three testosterone-blocking drugs prevents the spread of prostate cancer better than just a single medication, a new clinical trial has found." Dr Aggrawal again! https://www.usnews.com/news/health-news/articles/2024-01-25/multi-drug-combo-may-be-best-against-prostate-cancer
Maxone73
in
Advanced Prostate Cancer
4 months ago
How long to stay on blood thinners …and after ablation heart symptoms….
Good morning all, Since I haven’t heard from a doctor about blood thinners, how long should I stay on them after ablation? Thinking blanking period but I think here they said one month? After I eat dinner and walk the dog I start to get increases in heart rate (sitting down normally 60 but will be
Good morning all, Since I haven’t heard from a doctor about blood thinners, how long should I stay on them after ablation? Thinking blanking period but I think here they said one month? After I eat dinner and walk the dog I start to get increases in heart rate (sitting down normally 60 but will be
Chrissy7
in
Atrial Fibrillation Support
10 months ago
Bisoprolol - weird side effects on low dose?
I am wondering if I have developed
atrial
flutter
. I also get random stabbing chest pains on the left side, which are scary. Had an x-ray recently which found no issues in my heart or lungs. Anyway, the point of all this...
I am wondering if I have developed
atrial
flutter
. I also get random stabbing chest pains on the left side, which are scary. Had an x-ray recently which found no issues in my heart or lungs. Anyway, the point of all this...
tokenwelshman
in
AF Association
1 year ago
Does it indicate failure of another clinical trial
Annovis blames ‘data cleaning’ efforts for delaying phase 3 Parkinson’s readout https://www.fiercebiotech.com/biotech/annovis-blames-data-cleaning-efforts-delaying-phase-3-parkinsons-readout
Annovis blames ‘data cleaning’ efforts for delaying phase 3 Parkinson’s readout https://www.fiercebiotech.com/biotech/annovis-blames-data-cleaning-efforts-delaying-phase-3-parkinsons-readout
Farooqji
in
Cure Parkinson's
4 months ago
Clinical Trials
Has anyone participated in ANY Clinical Trials?? Which ones and have they helped at all???
Has anyone participated in ANY Clinical Trials?? Which ones and have they helped at all???
smv123
in
Cure Parkinson's
4 months ago
Vitamin D and Dementia
Vitamin D is a topic that gets a regular airing on this forum. In the context of CLL, here is a good place to review past posts https://healthunlocked.com/cllsupport/posts/149126536/recent-research-report?responses=149129259 (reply by Lankisterguy). Personally, the idea of dying with CLL just doesn't
Vitamin D is a topic that gets a regular airing on this forum. In the context of CLL, here is a good place to review past posts https://healthunlocked.com/cllsupport/posts/149126536/recent-research-report?responses=149129259 (reply by Lankisterguy). Personally, the idea of dying with CLL just doesn't
bennevisplace
in
CLL Support
4 months ago
Easy-to-use inhaled levodopa system readying request for US approval
That’s according to results from a company-sponsored clinical trial (NCT06037590) comparing the pharmacological properties of Levodopa Cyclops against those of Inbrija, an approved inhaled powder formulation of levodopa developed by Acorda Therapeutics. “This randomized cross-over trial of Levodopa
That’s according to results from a company-sponsored clinical trial (NCT06037590) comparing the pharmacological properties of Levodopa Cyclops against those of Inbrija, an approved inhaled powder formulation of levodopa developed by Acorda Therapeutics. “This randomized cross-over trial of Levodopa
Farooqji
in
Cure Parkinson's
4 months ago
clinical trial: ATR inhibitor for ATM mutated solid tumors
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
Maxone73
in
Advanced Prostate Cancer
4 months ago
Newly diagnosed AFib 40 year old
Hello everyone, last week I was diagnosed with persistent afib with lbbb and I'm terrified. I've been discharged with a bag of meds (bisoprolol, flecanide and rivaroxaban) and on the list for an ablation. I haven't been given much info and investigated everything myself. I just feel utterly depressed
Hello everyone, last week I was diagnosed with persistent afib with lbbb and I'm terrified. I've been discharged with a bag of meds (bisoprolol, flecanide and rivaroxaban) and on the list for an ablation. I haven't been given much info and investigated everything myself. I just feel utterly depressed
Harrgem
in
AF Association
10 months ago
Atrial Flutter
I was diagnosed with this five days after a vaccination which I have found out is automatically blocked on this forum. Having had no heart problems in my previous 62 years I discussed the matter with my consultant and with a GP. Both were dismissive but my suspicions remain as to the cause of my heart
I was diagnosed with this five days after a vaccination which I have found out is automatically blocked on this forum. Having had no heart problems in my previous 62 years I discussed the matter with my consultant and with a GP. Both were dismissive but my suspicions remain as to the cause of my heart
GrandpaM
in
British Heart Foundation
2 years ago
New Thyroid Results - Conversion Issue?
Hi, After an emotional Thyroid rollercoaster these past couple years (post partial thyroidectomy 12/2/21 in combination with an Endo who doesn't believe in compounded medication), I finally seem to be settling into a medication and dose that works okay. I'd have to say that I'm still a bit tired and
Hi, After an emotional Thyroid rollercoaster these past couple years (post partial thyroidectomy 12/2/21 in combination with an Endo who doesn't believe in compounded medication), I finally seem to be settling into a medication and dose that works okay. I'd have to say that I'm still a bit tired and
KarmaMaya
in
Thyroid UK
4 months ago
Current SUPERNOVA Clinical Trial for Reformulated EVUSHELD for preventing COVID-19 infection for immune-impaired individuals
A Phase II sub-study of SUPERNOVA clinical trial (2023) is currently operating to test the efficacy and safety of AZD3152 as a component of a reformulated version of EVUSHELD mAbs prophylaxis for immune-impaired individuals who cannot mount antibody responses to COVID-19 vaccines. Study Understanding
A Phase II sub-study of SUPERNOVA clinical trial (2023) is currently operating to test the efficacy and safety of AZD3152 as a component of a reformulated version of EVUSHELD mAbs prophylaxis for immune-impaired individuals who cannot mount antibody responses to COVID-19 vaccines. Study Understanding
Classicaljazz
in
CLL Support
4 months ago
After an AFib attack symptoms
I was diagnosed with AFib in October 2021 and am on an anticoagulant although I also take several medications for Hypertension including Bisoprol 15mg. Fortunately I have not had many AFib episodes although had one in the early hours of this morning.When I am having an AFib episode I find I need to pass
I was diagnosed with AFib in October 2021 and am on an anticoagulant although I also take several medications for Hypertension including Bisoprol 15mg. Fortunately I have not had many AFib episodes although had one in the early hours of this morning.When I am having an AFib episode I find I need to pass
Jomaur
in
Atrial Fibrillation Support
10 months ago
need some guidance, feeling desperate..
My husband has advanced, Stage IV castration resistant prostate cancer. When he was diagnosed in May 2022 his PSA was 4700, he has widespread bone metastases. He stopped responding to Docetaxel, Pluvicto and is now not responding to Cabazitaxel, his PSA is now over 700. He is feeling good, no pain
My husband has advanced, Stage IV castration resistant prostate cancer. When he was diagnosed in May 2022 his PSA was 4700, he has widespread bone metastases. He stopped responding to Docetaxel, Pluvicto and is now not responding to Cabazitaxel, his PSA is now over 700. He is feeling good, no pain
Kiki27
in
Advanced Prostate Cancer
4 months ago
Taste Issues and finger neuropathy on Xtandi( enzalutamide) ?
In order to participate in a clinical trial (FOR46 at UCSF) I had to switch from Nubeqa (darolutamide) to enzalutamide. Previously on abiraterone. Did really well on both medications. Now 4 months on enzalutamide and my 5th research infusion, I'm experiencing some side effects. Trying to determine
In order to participate in a clinical trial (FOR46 at UCSF) I had to switch from Nubeqa (darolutamide) to enzalutamide. Previously on abiraterone. Did really well on both medications. Now 4 months on enzalutamide and my 5th research infusion, I'm experiencing some side effects. Trying to determine
bandgeek
in
Advanced Prostate Cancer
4 months ago
I need some information and help
I am reaching out again to you wonderful people. Can you tell me if irregular heartbeat usually below 100, sometimes a bit over for five minutes is also atrial fibrillation. Are they the same thing I would like to understand - how this works. I have now had irregular heart beat that I can feel
I am reaching out again to you wonderful people. Can you tell me if irregular heartbeat usually below 100, sometimes a bit over for five minutes is also atrial fibrillation. Are they the same thing I would like to understand - how this works. I have now had irregular heart beat that I can feel
kitttycat
in
AF Association
10 months ago
Blood Thinners for RSL Sufferers
hi Rls friends, I have managed to withdraw from Pramipexole and have been taking Targinact 4.5/ naloxone Successfully for several months However, I have been admitted to hospital with a stroke and finding that I am dispairat this point( after 2 weeks) My usual Targinate has been replaced with a
hi Rls friends, I have managed to withdraw from Pramipexole and have been taking Targinact 4.5/ naloxone Successfully for several months However, I have been admitted to hospital with a stroke and finding that I am dispairat this point( after 2 weeks) My usual Targinate has been replaced with a
Jose651
in
Restless Legs Syndrome
10 months ago
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