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Should the dose of Dutasteride be increased?
The plot above shows the residual (nadir) level of DHT in men as a function of the daily Dutasteride dose (mg/day). The DHT nadir numbers shown in this plot are: 23.8 pg/mL for 0.5 mg daily dose; 10.2 pg/mL for 2.5 mg daily dose; and 7.3 pg/mL for 5 mg daily dose. Ref: Clark (2004) [see Table
The plot above shows the residual (nadir) level of DHT in men as a function of the daily Dutasteride dose (mg/day). The DHT nadir numbers shown in this plot are: 23.8 pg/mL for 0.5 mg daily dose; 10.2 pg/mL for 2.5 mg daily dose; and 7.3 pg/mL for 5 mg daily dose. Ref: Clark (2004) [see Table
janebob99
in
Prostate Cancer Network
3 months ago
Tinituus Quite in the morning
Good Morning All I’ve had pulsating tinnitus for just over a year. I feel I was well habituating it as I don’t notice it much throughout the day with ambient noise. In the evening in a quiet room I tend to use masking noise help me sleep. over the last couple of months, I found it more noticeable
Good Morning All I’ve had pulsating tinnitus for just over a year. I feel I was well habituating it as I don’t notice it much throughout the day with ambient noise. In the evening in a quiet room I tend to use masking noise help me sleep. over the last couple of months, I found it more noticeable
Marsh3l
in
Tinnitus UK
2 months ago
some great news….
My son will be turning 4 this January and that in and of itself is great news. Nothing is scarier than having just given birth and not knowing what the future of your precious new child will hold, like simply living. my son was born with PUV and severe reflux bilaterally. Of course there was renal
My son will be turning 4 this January and that in and of itself is great news. Nothing is scarier than having just given birth and not knowing what the future of your precious new child will hold, like simply living. my son was born with PUV and severe reflux bilaterally. Of course there was renal
MotherofBarbearians
in
Parents of Children with Kidney Disease
6 months ago
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ECT? Keen for peoples lived experiences
I’ve been referred for ECT and keen to hear from people who’ve had the treatment or in the process and how it was/is for you. The overall result - good bad or neutral? If there’s any good or bad things you experienced. Any tips? Would you do it again if needed? Any feedback would be gratefully
I’ve been referred for ECT and keen to hear from people who’ve had the treatment or in the process and how it was/is for you. The overall result - good bad or neutral? If there’s any good or bad things you experienced. Any tips? Would you do it again if needed? Any feedback would be gratefully
Hidden
in
Major Depressive Disorder (MDD) Support
2 months ago
15y ADHD Med Trial & Error
Hi Everyone! I am new to this forum but wanted to reach out to see if any one has had some recommendations or tips.My daughter is 15 and has been diagnosed with ADHD recently. She was taking 30mg of Vyvanse which seemed to help but she was still unable to focus. After about a month it was increased to
Hi Everyone! I am new to this forum but wanted to reach out to see if any one has had some recommendations or tips.My daughter is 15 and has been diagnosed with ADHD recently. She was taking 30mg of Vyvanse which seemed to help but she was still unable to focus. After about a month it was increased to
PinkMamabear1990
in
CHADD's ADHD Parents Together
2 months ago
I have PA, all was going well, but now they're trying to mess with my b12 perscipton!!!
Hi all,I'm a long time lurker, but haven't posted myself in a while. About 8 years ago, I was fighting to save my right leg due to bone tumors. 12 surgeries later, I lost that fight. During that time, I started losing weight, tons of anxiety, palpitations ect...This would all be normal reaction to this
Hi all,I'm a long time lurker, but haven't posted myself in a while. About 8 years ago, I was fighting to save my right leg due to bone tumors. 12 surgeries later, I lost that fight. During that time, I started losing weight, tons of anxiety, palpitations ect...This would all be normal reaction to this
Wowo23
in
Pernicious Anaemia Society
2 months ago
Started new thyroid medication Mon 😡
Sorry everyone but this is going to be a rant.... As many members will know I stopped taking my thyroid medication on January 31st because the incompetent endo put me back on teva, which I certainly don't get on with (gastric side effects amongst other side effects) Through my surgeon in Liverpool for
Sorry everyone but this is going to be a rant.... As many members will know I stopped taking my thyroid medication on January 31st because the incompetent endo put me back on teva, which I certainly don't get on with (gastric side effects amongst other side effects) Through my surgeon in Liverpool for
birkie
in
Thyroid UK
2 months ago
What are the most promising drugs/treatments on the horizon for PD symptom relief,slowing progression?
I see Buntanetap,Celeste light therapy and Cue1 as potentials. anyone have any thoughts? i dont know how much longer I can hang on.
I see Buntanetap,Celeste light therapy and Cue1 as potentials. anyone have any thoughts? i dont know how much longer I can hang on.
Jmellano
in
Cure Parkinson's
6 months ago
Newly diagnosed metastatic PC treatment options
Hi, I'm 68 years old. Here are the key points in my story so far: In July 2023 a blood test showed a PSA value of 45. On September 26 2023, prostate MRI showed a dominant tumor in the prostate with extension into the right seminal vesicle. Also the fat plane between the rectum and prostate is lost
Hi, I'm 68 years old. Here are the key points in my story so far: In July 2023 a blood test showed a PSA value of 45. On September 26 2023, prostate MRI showed a dominant tumor in the prostate with extension into the right seminal vesicle. Also the fat plane between the rectum and prostate is lost
ShorePine
in
Advanced Prostate Cancer
6 months ago
New 2024 AUA/ASTRO/SUO Guidelines for Salvage Therapy
https://www.auanet.org/guidelines-and-quality/guidelines/salvage-therapy-for-prostate-cancer Not surprising. I think they should recommend adjuvant ADT at a PSA≥0.35 instead of ≥0.7 because I think patients are hoping for curative SRT and not just equivalent survival. https://www.prostatecancer.news
https://www.auanet.org/guidelines-and-quality/guidelines/salvage-therapy-for-prostate-cancer Not surprising. I think they should recommend adjuvant ADT at a PSA≥0.35 instead of ≥0.7 because I think patients are hoping for curative SRT and not just equivalent survival. https://www.prostatecancer.news
Tall_Allen
in
Advanced Prostate Cancer
3 months ago
hyperbaric Oxygen Therapy
A friend of mine with osteoporosis recently broke her leg and used Hyperbaric Oxygen therapy which accelerated healing and apparently stimulates osteoclasts. Has anyone here used this for osteoporosis without a fracture, and if so, do you have results to share?
A friend of mine with osteoporosis recently broke her leg and used Hyperbaric Oxygen therapy which accelerated healing and apparently stimulates osteoclasts. Has anyone here used this for osteoporosis without a fracture, and if so, do you have results to share?
HealthELiving
in
Bone Health and Osteoporosis UK
2 months ago
Surgery options
Hi everyone, I really need some advice! I have had severe pains everyday for a year along with fatigue, nausea ect. Everything's been ruled out apart from endometriosis which is what all my symptoms and history points at. I booked an appointment with a specalist last year and he gave me meds and told
Hi everyone, I really need some advice! I have had severe pains everyday for a year along with fatigue, nausea ect. Everything's been ruled out apart from endometriosis which is what all my symptoms and history points at. I booked an appointment with a specalist last year and he gave me meds and told
Lavenderpetal
in
Endometriosis UK
2 months ago
Robert
Robert was diagnosed with Parkinson’s in 2018 PSP in 2021 progression was slow at first. Last year Robert was walking with a cane and dragging his feet. In September he began to fall daily sometimes more. He got weaker every day and finally allowed me to call a rescue. What followed was a whirlwind
Robert was diagnosed with Parkinson’s in 2018 PSP in 2021 progression was slow at first. Last year Robert was walking with a cane and dragging his feet. In September he began to fall daily sometimes more. He got weaker every day and finally allowed me to call a rescue. What followed was a whirlwind
Wrski
in
PSP Association
7 months ago
Blood results interpretation required
Hi there, I need help interpreting my results. My symptoms are brain fog, joint aches, lack of energy and anxiety. These have been with me all my life. They got better in 2022 when I started combination therapy. However, I do not think I have reached my optimum (whatever that is) because these symptoms
Hi there, I need help interpreting my results. My symptoms are brain fog, joint aches, lack of energy and anxiety. These have been with me all my life. They got better in 2022 when I started combination therapy. However, I do not think I have reached my optimum (whatever that is) because these symptoms
Carlax
in
Thyroid UK
3 months ago
Light Therapy Celeste
Photopharmics is getting ready to recruit for phase 3. For those interested: https://photopharmics.com/innovative-research-inclusive-trials-and-new-funding-drives-hope-for-people-with-parkinsons-disease/
Photopharmics is getting ready to recruit for phase 3. For those interested: https://photopharmics.com/innovative-research-inclusive-trials-and-new-funding-drives-hope-for-people-with-parkinsons-disease/
Pegcity
in
Cure Parkinson's
7 months ago
Studies comparing Levo mono vs Levo/Lio combo T4/T3 treatment
Batty1shared an article here https://healthunlocked.com/thyroiduk/posts/150566060/why-don’t-doctors-know-deal-with-this-hypothyroid-issue That lead me to a rabbit hole on the American Thyroid Association website. Sharing a summary of what I found to be a very comprehensive presentation of studies
Batty1shared an article here https://healthunlocked.com/thyroiduk/posts/150566060/why-don’t-doctors-know-deal-with-this-hypothyroid-issue That lead me to a rabbit hole on the American Thyroid Association website. Sharing a summary of what I found to be a very comprehensive presentation of studies
FallingInReverse
in
Thyroid UK
3 months ago
misunderstood peri -menopause treatment
I had a very traumatic experience in my peri menopause. Due to heavy bleeding and clotting in my last 2 years of peri menopause I was hospitalized with an anemia. Given tablets to help stem bleeding and they caused jaundice. Was offered hysteroscopy under NHS however not given the option for sedation
I had a very traumatic experience in my peri menopause. Due to heavy bleeding and clotting in my last 2 years of peri menopause I was hospitalized with an anemia. Given tablets to help stem bleeding and they caused jaundice. Was offered hysteroscopy under NHS however not given the option for sedation
Charlysangel
in
Women's Health
2 months ago
PSA rising on Triplet Therapy after <18m
Hi all. Hope you are keeping your spirits high. This is a follow up to a post I made in 2022 about my father. I haven't posted since, which reflects the period of relative normalcy that followed the commencement of ADT (triplet therapy) at MSK. I want to pause to appreciate that since I know most of
Hi all. Hope you are keeping your spirits high. This is a follow up to a post I made in 2022 about my father. I haven't posted since, which reflects the period of relative normalcy that followed the commencement of ADT (triplet therapy) at MSK. I want to pause to appreciate that since I know most of
nyc_son
in
Advanced Prostate Cancer
3 months ago
Care Home response
Please can I thank everyone who sent a response to my original post. It is encouraging to hear from so many of you who have similar stories. My husband is responding well to the care home and the staff are lovely. I have had a lot of support from the health professionals , consultant, physio, speech
Please can I thank everyone who sent a response to my original post. It is encouraging to hear from so many of you who have similar stories. My husband is responding well to the care home and the staff are lovely. I have had a lot of support from the health professionals , consultant, physio, speech
Wybert
in
PSP Association
7 months ago
Extremely interesting....
The Swinging Pendulum in Treatment for Hypothyroidism: From (and Toward?) Combination Therapy - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629976/
The Swinging Pendulum in Treatment for Hypothyroidism: From (and Toward?) Combination Therapy - PMC https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629976/
Easylover
in
Thyroid UK
7 months ago
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