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Gene therapy
I know it's not PD but it is a neurological condition and sounds like a hopeful developmentUK toddler has hearing restored in world first
gene
therapy
trial https://www.theguardian.com/science/article/2024/may/09/uk-toddler-has-hearing-restored-in-world-first-
gene
-
therapy
-trial?CMP=share_btn_url
I know it's not PD but it is a neurological condition and sounds like a hopeful developmentUK toddler has hearing restored in world first
gene
therapy
trial https://www.theguardian.com/science/article/2024/may/09/uk-toddler-has-hearing-restored-in-world-first-
gene
-
therapy
-trial?CMP=share_btn_url
WinnieThePoo
in
Cure Parkinson's
1 month ago
Gene therapy
'eurologyLioe https://www.neurologylive.com/view/realistic-expectations-limitations-
gene
-
therapy
-parkinson-disease-ignacio-mata
'eurologyLioe https://www.neurologylive.com/view/realistic-expectations-limitations-
gene
-
therapy
-parkinson-disease-ignacio-mata
Farooqji
in
Cure Parkinson's
4 months ago
Swanbio gene therapy study
Anyone know how this study is going? I did a google search and there was something posted a few days ago but you had to buy the report. $500. I’m very interested but information seems hard to come by. It doesn’t sound like it would repair damage but stop or slow the disease. I wonder if it would eliminate
Anyone know how this study is going? I did a google search and there was something posted a few days ago but you had to buy the report. $500. I’m very interested but information seems hard to come by. It doesn’t sound like it would repair damage but stop or slow the disease. I wonder if it would eliminate
Golfdog3
in
AMN EASIER
3 months ago
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AB-1005
By posting this I am not necessarily advocating this treatment just trying to find out more information on how it is made and how it is administered [u]
Gene
therapy
AB-1005 found safe in Phase 1b Parkinson’s trial[/u] https://parkinsonsnewstoday.com/news/
gene
-
therapy
-ab-1005-safe-phase-1b-trial/?
By posting this I am not necessarily advocating this treatment just trying to find out more information on how it is made and how it is administered [u]
Gene
therapy
AB-1005 found safe in Phase 1b Parkinson’s trial[/u] https://parkinsonsnewstoday.com/news/
gene
-
therapy
-ab-1005-safe-phase-1b-trial/?
Boscoejean
in
Cure Parkinson's
5 months ago
Bayer and AskBio report data from Parkinson’s disease therapy trial
The bilateral infusions of AB-1005 were well tolerated, without any SAEs linked to the
gene
therapy
or contrast agent.
The bilateral infusions of AB-1005 were well tolerated, without any SAEs linked to the
gene
therapy
or contrast agent.
Farooqji
in
Cure Parkinson's
2 months ago
AAV-GAD Gene Therapy
Did anyone hear of AAV-GAD
gene
therapy
? I have a chance to get into a phase 1/2 trial, but information is somewhat limited. The original developing company went bankrupt, and a new company bought the rights to the therapy.
Did anyone hear of AAV-GAD
gene
therapy
? I have a chance to get into a phase 1/2 trial, but information is somewhat limited. The original developing company went bankrupt, and a new company bought the rights to the therapy.
JohnP65
in
Cure Parkinson's
6 months ago
CRISPR 13 (what? you thought I abandoned CRISPR?): very promising proof of concept - Targeting HOXB13 in mPCa by CRISPR/Cas13d- nanoparticle
And people thought it was undruggable....they have already filed for a patent 😲 Researchers developed nanoparticles that can deliver a special type of
gene
therapy
directly to cancer cells in the liver.
And people thought it was undruggable....they have already filed for a patent 😲 Researchers developed nanoparticles that can deliver a special type of
gene
therapy
directly to cancer cells in the liver.
Maxone73
in
Advanced Prostate Cancer
2 months ago
Neurological Disorders: How Regenerative Medicines Help in Treating Nervous System Diseases
Discover cutting-edge techniques such as stem cell
therapy
,
gene
therapy
, and surgical innovations that are reshaping the landscape of neurology. Regenerative medicine is offering new hope and possibilities for individuals grappling with neurological challenges.
Discover cutting-edge techniques such as stem cell
therapy
,
gene
therapy
, and surgical innovations that are reshaping the landscape of neurology. Regenerative medicine is offering new hope and possibilities for individuals grappling with neurological challenges.
Farooqji
in
Cure Parkinson's
5 months ago
Targeted Gene Therapy for Symptom Relief in Parkinson’s Disease
https://www.brainpost.co/weekly-brainpost/2023/11/7/targeted-
gene
-
therapy
-for-symptom-relief-in-parkinsons-disease
https://www.brainpost.co/weekly-brainpost/2023/11/7/targeted-
gene
-
therapy
-for-symptom-relief-in-parkinsons-disease
Neurosmith
in
Cure Parkinson's
7 months ago
Aspen Neuroscience to Present at International Society for Cell & Gene Therapy (ISCT) Annual Meeting
iPSCs and Dopaminergic Neuron Precursor Cells for Parkinson's Disease Presenter: Daniel Fremgen Director, Analytical Development, Aspen Neuroscience Time: 10:30 - 11:30am PT https://www.prnewswire.com/news-releases/aspen-neuroscience-to-present-at-international-society-for-cell--
gene
-
therapy
-isct-annual-meeting
iPSCs and Dopaminergic Neuron Precursor Cells for Parkinson's Disease Presenter: Daniel Fremgen Director, Analytical Development, Aspen Neuroscience Time: 10:30 - 11:30am PT https://www.prnewswire.com/news-releases/aspen-neuroscience-to-present-at-international-society-for-cell--
gene
-
therapy
-isct-annual-meeting
Farooqji
in
Cure Parkinson's
15 days ago
Let's enjoy some predictions: cell and gene therapy in 2024
https://www.massgeneralbrigham.org/en/about/newsroom/articles/2024-predictions-about-
gene
-and-cell-
therapy
https://www.massgeneralbrigham.org/en/about/newsroom/articles/2024-predictions-about-
gene
-and-cell-
therapy
Maxone73
in
Advanced Prostate Cancer
5 months ago
Replace or reorganize neurons
Via vibration Where
gene
therapy
assume we have a loss of Neurons that need to be replaced ? Which is it, replace or reorganize?
Via vibration Where
gene
therapy
assume we have a loss of Neurons that need to be replaced ? Which is it, replace or reorganize?
bigl62
in
Cure Parkinson's
7 months ago
Caffeic acid phenethyl ester (CAPE) is an ingredient in bee propolis. See below for invitro and mice evidence for inhibition AR-V7 by CAPE
Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer
Gene
Therapy
(2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant 7 (AR-V7) is capable
Caffeic acid phenethyl ester suppresses the expression of androgen receptor variant 7 via inhibition of CDK1 and AKT Ying-Yu Kuo, Chieh Huo, Chia-Yang Li & Chih-Pin Chuu Cancer
Gene
Therapy
(2024) doi: 10.1038/s41417-024-00753-z Abstract Androgen receptor (AR) splice variant 7 (AR-V7) is capable
Graham49
in
Advanced Prostate Cancer
3 months ago
Secondary Cancers after CAR-T Cell Therapy
[/i] [i]Although CAR-T products have to date been associated with fewer cancers than products made with the previous generation of viruses used for
gene
therapy
transduction, the potential for oncogenesis caused by genomic integration or other mechanisms still exists with the current generation of retroviral
[/i] [i]Although CAR-T products have to date been associated with fewer cancers than products made with the previous generation of viruses used for
gene
therapy
transduction, the potential for oncogenesis caused by genomic integration or other mechanisms still exists with the current generation of retroviral
Jm954
Administrator
in
CLL Support
5 months ago
FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks
"Finally, we know that cancer immunotherapy such as checkpoint blockade for solid tumors, which does not rely on
gene
therapy
, can very rarely result in T-cell lymphomas."
"Finally, we know that cancer immunotherapy such as checkpoint blockade for solid tumors, which does not rely on
gene
therapy
, can very rarely result in T-cell lymphomas."
cujoe
in
CLL Support
7 months ago
BBB opening with focused ultrasound in nonhuman primates and Parkinson’s disease patients:
They can now briefly open select spots in the brain barrier using focused ultrasound and deliver larger particles like
gene
therapy
(in microbubbles). So it would allow for minimally invasive, early treatment of neurological disorders. https://www.science.org/doi/10.1126/sciadv.adf4888?
They can now briefly open select spots in the brain barrier using focused ultrasound and deliver larger particles like
gene
therapy
(in microbubbles). So it would allow for minimally invasive, early treatment of neurological disorders. https://www.science.org/doi/10.1126/sciadv.adf4888?
LeharLover62
in
Cure Parkinson's
11 months ago
Not PCa related but sounds like a very promising approach
https://ascopost.com/news/april-2024/advanced-pancreatic-cancer-oncolytic-virus-based-immunostimulatory-
gene
-
therapy
-plus-chemotherapy/
https://ascopost.com/news/april-2024/advanced-pancreatic-cancer-oncolytic-virus-based-immunostimulatory-
gene
-
therapy
-plus-chemotherapy/
Maxone73
in
Advanced Prostate Cancer
2 months ago
Megan's Update from Mission: Cure
⚠️ Acrigen Update You may be aware of our collaboration with Acrigen Biosciences, a biotech company pioneering the first
gene
therapy
for PRSS1 hereditary pancreatitis. Acrigen demonstrated in the lab that its technology could successfully edit the PRSS1 gene.
⚠️ Acrigen Update You may be aware of our collaboration with Acrigen Biosciences, a biotech company pioneering the first
gene
therapy
for PRSS1 hereditary pancreatitis. Acrigen demonstrated in the lab that its technology could successfully edit the PRSS1 gene.
Skye_MC
Administrator
in
Chronic Pancreatitis Support
8 months ago
Genetic therapy: for solid malignancy hopefully soon
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
Maxone73
in
Advanced Prostate Cancer
7 months ago
TCR Gene Therapy
the science to cure us is coming https://www.youtube.com/watch?v=LIvVMIcRTew
the science to cure us is coming https://www.youtube.com/watch?v=LIvVMIcRTew
Scout4answers
in
Advanced Prostate Cancer
1 year ago
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