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Apalutamide plus abiraterone acetate and prednisone versus placebo plus abiraterone and prednisone in metastatic, CRPC
abiraterone
-prednisone; 490 to
abiraterone
-prednisone).
abiraterone
-prednisone; 490 to
abiraterone
-prednisone).
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Half Dose Abiraterone
Does anybody on here half dose
abiraterone
and if so, is it as successful as full dose? Thanks!
Does anybody on here half dose
abiraterone
and if so, is it as successful as full dose? Thanks!
Hillwalker87
in
Advanced Prostate Cancer
3 years ago
Zoladex, Abiraterone and Chemo
Hi everyone, Is it dangerous to have the above three agents all at once? Thanks!
Hi everyone, Is it dangerous to have the above three agents all at once? Thanks!
Hillwalker87
in
Advanced Prostate Cancer
3 years ago
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Got PSMA SCAN Results-Now What?
Dr Sartor was able to start me on 1000 mg of
abiraterone
acetate (Zytiga) and 5 mg of prednisone, that same day. April 9 a local oncologist gave me a 3 month dose of leoprolide acetate (Lupron).
Dr Sartor was able to start me on 1000 mg of
abiraterone
acetate (Zytiga) and 5 mg of prednisone, that same day. April 9 a local oncologist gave me a 3 month dose of leoprolide acetate (Lupron).
Skippy3
in
Advanced Prostate Cancer
2 years ago
Abiraterone Active in Androgen Receptor-Positive Salivary Tumors — Disease control in 62.5% of a small cohort . . . MedPage Today - 10/14/21
xid=nl_mpt_DHE_2021-10-15 and also to the ASCO full report out of Italy:
Acetate in Patients With Castration-Resistant, Androgen Receptor–Expressing Salivary Gland Cancer: A Phase II Trial https://ascopubs.org/doi/full/10.1200/JCO.21.00468 [i] Knowledge is power, so stay Informed
xid=nl_mpt_DHE_2021-10-15 and also to the ASCO full report out of Italy:
Acetate in Patients With Castration-Resistant, Androgen Receptor–Expressing Salivary Gland Cancer: A Phase II Trial https://ascopubs.org/doi/full/10.1200/JCO.21.00468 [i] Knowledge is power, so stay Informed
cujoe
in
Fight Prostate Cancer
3 years ago
My Orchiectomy Adventure
After my last lab showed an increasing PSA while on both Eligard and
Abiraterone
he told me he 100% supported it. I already had an appointment set up with a urologist because of a lot of discomfort and sometimes pain in my testicles.
After my last lab showed an increasing PSA while on both Eligard and
Abiraterone
he told me he 100% supported it. I already had an appointment set up with a urologist because of a lot of discomfort and sometimes pain in my testicles.
33Ford
in
Advanced Prostate Cancer
3 years ago
Started chemo after abiraterone failure-need help!!!
Has anyone got a good response in mCRPC with docetaxel after failing
abiraterone
?
Has anyone got a good response in mCRPC with docetaxel after failing
abiraterone
?
Vsahay
in
Advanced Prostate Cancer
3 years ago
Cardio risk and abi/enza
elsca1=emc_enews_topic-alert "These data suggest an increased risk of stroke or MI with
abiraterone
use compared with enzalutamide, suggesting that enzalutamide may be indicated in patients with prostate cancer with a high cardiovascular risk."
elsca1=emc_enews_topic-alert "These data suggest an increased risk of stroke or MI with
abiraterone
use compared with enzalutamide, suggesting that enzalutamide may be indicated in patients with prostate cancer with a high cardiovascular risk."
kaptank
in
Advanced Prostate Cancer
3 years ago
Abiraterone keeps men with prostate cancer at risk of spreading alive for longer
https://www.icr.ac.uk/news-archive/
abiraterone
-keeps-men-with-prostate-cancer-at-risk-of-spreading-alive-for-longer
https://www.icr.ac.uk/news-archive/
abiraterone
-keeps-men-with-prostate-cancer-at-risk-of-spreading-alive-for-longer
sarkozy
in
Advanced Prostate Cancer
3 years ago
Androgen Receptor [AR] Axis Therapies
The influence of prior
abiraterone
treatment on the clinical activity of docetaxel in men with metastatic castration-resistant prostate cancer. Eur Urol. 2014;66:646-652. Bandini M, Mazzone E, Preisser F, et al.
The influence of prior
abiraterone
treatment on the clinical activity of docetaxel in men with metastatic castration-resistant prostate cancer. Eur Urol. 2014;66:646-652. Bandini M, Mazzone E, Preisser F, et al.
pjoshea13
in
Advanced Prostate Cancer
3 years ago
PLEASE HELP ... REALLY NEED YOUR INPUT ... THANKS !
What are your thoughts /experiences regarding using aplutamide or darolutamide or
abiraterone
instead ? C. What are your thoughts / experiences on doing
abiraterone
first and, if it fails then enzalutamide versus ennzi first; abi second ? C.
What are your thoughts /experiences regarding using aplutamide or darolutamide or
abiraterone
instead ? C. What are your thoughts / experiences on doing
abiraterone
first and, if it fails then enzalutamide versus ennzi first; abi second ? C.
Nous
in
Advanced Prostate Cancer
3 years ago
ADT + Abirterone Failing what's Next?
What if I take chemo with Xtandi instead of
Abiraterone
and Orgovyx? Any thoughts? What has worked before when the PCa is out of control?
What if I take chemo with Xtandi instead of
Abiraterone
and Orgovyx? Any thoughts? What has worked before when the PCa is out of control?
Back2future
in
Advanced Prostate Cancer
3 years ago
Is my Testosterone high?
(Lupron 6 mon shots,
Abiraterone
, & prednisone) Was switched to Eligard on Monday. Bloodwork Monday showed PSA undetectable and testosterone at 51 ng/dL. Is the testosterone high for being on ADT??
(Lupron 6 mon shots,
Abiraterone
, & prednisone) Was switched to Eligard on Monday. Bloodwork Monday showed PSA undetectable and testosterone at 51 ng/dL. Is the testosterone high for being on ADT??
Dlanghorne
in
Advanced Prostate Cancer
3 years ago
Is it time to add Abi+Docetaxel to current ADT?
My MO said that no need to have combination of ADT+
ABIRATERONE
+DOCETAXEL although early use it has benefits but we need to wait till PSA starts to increase. Currently ADT gives good result. But I know from past topics here that early use of that combo extends 2-2.5 years castraction period .
My MO said that no need to have combination of ADT+
ABIRATERONE
+DOCETAXEL although early use it has benefits but we need to wait till PSA starts to increase. Currently ADT gives good result. But I know from past topics here that early use of that combo extends 2-2.5 years castraction period .
LastMohikan
in
Advanced Prostate Cancer
3 years ago
Venous thromboembolism in metastatic castration-resistant cancer patients
"These results first suggest that baseline ptDNA fraction in mCRPC patients treated with
abiraterone
or enzalutamide may be associated with increased VTE risk.
"These results first suggest that baseline ptDNA fraction in mCRPC patients treated with
abiraterone
or enzalutamide may be associated with increased VTE risk.
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Neuroendocrine Prostate Cancer [NEPC]
By contrast, [i]multiple studies suggest that t-NEPC arises from adenocarcinomas as a consequence of an adaptive response to therapy, and the incidence of t-NEPC has been increasing due to the wide use of potent androgen receptor targeted agents (ARTAs), such as enzalutamide,
abiraterone
acetate, apalutamide
By contrast, [i]multiple studies suggest that t-NEPC arises from adenocarcinomas as a consequence of an adaptive response to therapy, and the incidence of t-NEPC has been increasing due to the wide use of potent androgen receptor targeted agents (ARTAs), such as enzalutamide,
abiraterone
acetate, apalutamide
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Two years Results
Treatments: 1)Lupron shot every 3 months effective December 2019. 2)Radiation to Pelvic for 4 weeks February 2020 3)
Abiraterone
250 mg with a low-fat breakfast + Prednisone 5 mg every day effective January 2020 Results: 04/14/20 PSA<0.03, 06/09/20 PSA<0.03, 07/31/20 PSA<0.03 & 09/30/20 PSA<0.03, 12
Treatments: 1)Lupron shot every 3 months effective December 2019. 2)Radiation to Pelvic for 4 weeks February 2020 3)
Abiraterone
250 mg with a low-fat breakfast + Prednisone 5 mg every day effective January 2020 Results: 04/14/20 PSA<0.03, 06/09/20 PSA<0.03, 07/31/20 PSA<0.03 & 09/30/20 PSA<0.03, 12
Pheart2
in
Advanced Prostate Cancer
3 years ago
Any thoughts on why PSA rising but mets status stable?
I am writing for my dad who was diagnosed with PCa in 2010, after using ADT,
Abiraterone
, Olaprib, Provenge(Car-T) and now his PSA is about 5.2, with 5 mets on lliac and neck lymphatic.
I am writing for my dad who was diagnosed with PCa in 2010, after using ADT,
Abiraterone
, Olaprib, Provenge(Car-T) and now his PSA is about 5.2, with 5 mets on lliac and neck lymphatic.
MacWong
in
Advanced Prostate Cancer
3 years ago
Dasatinib
From 2019 [7]: "
Randomized Phase II Trial of
Alone or With Dasatinib in Men With Metastatic Castration-resistant Prostate Cancer (mCRPC)" "The Src family kinases have a proven role in tumorigenesis and in progression of various solid tumors, reviewed by Summy et al.19 Interactions
From 2019 [7]: "
Randomized Phase II Trial of
Alone or With Dasatinib in Men With Metastatic Castration-resistant Prostate Cancer (mCRPC)" "The Src family kinases have a proven role in tumorigenesis and in progression of various solid tumors, reviewed by Summy et al.19 Interactions
pjoshea13
in
Advanced Prostate Cancer
3 years ago
New Member Scouting for answers; To radiate now or not
Plan they have mapped out at is to take Lupron and
Abiraterone
for 2 years and radiate prostate bed and two lymph nodes for 28 sessions starting soon after starting
Abiraterone
.
Plan they have mapped out at is to take Lupron and
Abiraterone
for 2 years and radiate prostate bed and two lymph nodes for 28 sessions starting soon after starting
Abiraterone
.
Scout4answers
in
Advanced Prostate Cancer
3 years ago
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