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Tetanus Vaccine Decreases Incidence of Parkinson’s Disease and Slows Its Progression
In tetanus, the neurotoxin is internalized into signaling endosomes and transported retrogradely to the neuronal
soma
, interfering with the release of neurotransmitters, notably glycine and gamma-aminobutyric acid, blocking inhibitory impulses(5).
In tetanus, the neurotoxin is internalized into signaling endosomes and transported retrogradely to the neuronal
soma
, interfering with the release of neurotransmitters, notably glycine and gamma-aminobutyric acid, blocking inhibitory impulses(5).
Bolt_Upright
in
Cure Parkinson's
19 days ago
Need surgery
Hi I'm not new here but I thought I'd take a shot in the dark and explain the predicament that I am in. I have a prolapsed stoma which is 4 inches long and 55mm in diameter I've also herniated my bowel with it being 10cm in length. I also have 1 metre of small bowel left so not really much at all when
Hi I'm not new here but I thought I'd take a shot in the dark and explain the predicament that I am in. I have a prolapsed stoma which is 4 inches long and 55mm in diameter I've also herniated my bowel with it being 10cm in length. I also have 1 metre of small bowel left so not really much at all when
Joeyskin
in
IBS Network
2 days ago
Struggling Financially with Leukaemia?
I was diagnosed with CLL in July 2013 and had already been registered with Macmillan in 2004 when I had bowel cancer, although at that time I didn't need much help other than problems with stoma bags and local support groups, both of which they helped me with. Financially I was okay being paid by my
I was diagnosed with CLL in July 2013 and had already been registered with Macmillan in 2004 when I had bowel cancer, although at that time I didn't need much help other than problems with stoma bags and local support groups, both of which they helped me with. Financially I was okay being paid by my
clifflee
in
CLL Support
7 days ago
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NICE colostomy consultation - invitation to Ovacome focus group
Good morning everyone, We have been contacted by the National Institute for Health and Care Excellence (NICE) as they are currently undertaking an assessment looking at one-piece closed stoma bags for adults with a colostomy. We would like to contribute to this assessment by making a submission as we
Good morning everyone, We have been contacted by the National Institute for Health and Care Excellence (NICE) as they are currently undertaking an assessment looking at one-piece closed stoma bags for adults with a colostomy. We would like to contribute to this assessment by making a submission as we
OvacomeSupport
My Ovacome Team
in
My Ovacome
8 days ago
Mum in ICU
Hi all , I’m at the beginning of my mums ICU journey and I’m so glad I came across this page . Up until last Friday my mum at 76 had a few health problems as you would expect but was still the main carer for my dad who has Parkinson’s . All last week she was complaining of tummy ache and to cut a long
Hi all , I’m at the beginning of my mums ICU journey and I’m so glad I came across this page . Up until last Friday my mum at 76 had a few health problems as you would expect but was still the main carer for my dad who has Parkinson’s . All last week she was complaining of tummy ache and to cut a long
Exhausted247
in
ICUsteps
13 days ago
Recurence
Hi wondered what side effects with niropirad as am being offereredjust out hospital after total hysterectomy omentom removed and shock stoma was given mopup chemo that put me in hospital just don't feel ready for more treatments as last year in out of hospital no normal life been told they removed
Hi wondered what side effects with niropirad as am being offereredjust out hospital after total hysterectomy omentom removed and shock stoma was given mopup chemo that put me in hospital just don't feel ready for more treatments as last year in out of hospital no normal life been told they removed
PaumicB123
in
My Ovacome
16 days ago
Does anyone know how long surgery is from your MDT meeting?
Hi warriors, I've just had my results from my MDT meeting. I've got to have a consent/discussion consultation and another with a bowel consultation incase I need a stoma. My question is, does anyone have a time scale of when they got surgery after the MDT meeting. I'm under Cambridge team. Thankyou
Hi warriors, I've just had my results from my MDT meeting. I've got to have a consent/discussion consultation and another with a bowel consultation incase I need a stoma. My question is, does anyone have a time scale of when they got surgery after the MDT meeting. I'm under Cambridge team. Thankyou
Loveneige
in
Endometriosis UK
18 days ago
What's on at Ovacome next week? (week commencing Monday 13 May 2024)
Good afternoon everyone This is our weekly post to let you know about the different support groups, workshops and events taking place at Ovacome next week. Monday 13 May - Monday monthly meet - up between 4:00pm and 5:30pm: https://www.ovacome.org.uk/Event/monday-monthly-meet-up Tuesday 14 May -
Good afternoon everyone This is our weekly post to let you know about the different support groups, workshops and events taking place at Ovacome next week. Monday 13 May - Monday monthly meet - up between 4:00pm and 5:30pm: https://www.ovacome.org.uk/Event/monday-monthly-meet-up Tuesday 14 May -
OvacomeSupport
My Ovacome Team
in
My Ovacome
27 days ago
Dealing with endo after children in late thirties
hi there I’m 37 and had two children via IVF when I was 33 and 35. I have stage 4 recto vaginal endometriosis and had a bowel resection and temporary stoma when I was 31 before starting IVF. Now I’m finished having children, I’ve gone back on the pill and run it back to back to prevent periods. I’m
hi there I’m 37 and had two children via IVF when I was 33 and 35. I have stage 4 recto vaginal endometriosis and had a bowel resection and temporary stoma when I was 31 before starting IVF. Now I’m finished having children, I’ve gone back on the pill and run it back to back to prevent periods. I’m
EKP31
in
Endometriosis UK
27 days ago
Tibilone experiences
Hi. I have very severe endometriosis and adenomyosis and am awaiting surgery which will likely involve having a stoma. I’ve previously had left ovary removed and both tubes and I’ve recently been told my right ovary is failing. Unfortunately there was been little improvement to my Endometriosis even
Hi. I have very severe endometriosis and adenomyosis and am awaiting surgery which will likely involve having a stoma. I’ve previously had left ovary removed and both tubes and I’ve recently been told my right ovary is failing. Unfortunately there was been little improvement to my Endometriosis even
Lily1986
in
Endometriosis UK
1 month ago
diverticulitis incontinence
Diverticulitis hot of nowhere. I fell down the stairs, was life flighted to UH main Campus, and had multiple Harkin’s procedures. Gutted thrice, like a catfish. I’ll be with ostomy for rest of my life. It’s been 40 days. Weak as a kitten I’m just in to rehab but still draining. They equipped me
Diverticulitis hot of nowhere. I fell down the stairs, was life flighted to UH main Campus, and had multiple Harkin’s procedures. Gutted thrice, like a catfish. I’ll be with ostomy for rest of my life. It’s been 40 days. Weak as a kitten I’m just in to rehab but still draining. They equipped me
kreg001
in
Advanced Prostate Cancer
1 month ago
Ilieostomy - waistband issue
We're gradually feeling our way through things but my husband has advised me that he is having difficulties with waistbands - he either needs to pull his trousers up really high or have his trousers hanging really low. Is there any solution, for instance to the support belts help. I did buy him ilieostomy
We're gradually feeling our way through things but my husband has advised me that he is having difficulties with waistbands - he either needs to pull his trousers up really high or have his trousers hanging really low. Is there any solution, for instance to the support belts help. I did buy him ilieostomy
Suebedoo
in
Living with a Stoma
1 month ago
Bowel or endometrioma pain?
Hi I'm hoping someone can shed a bit of light on my pain. I have endo in lots of places in POD on ligaments and my bowel.I also have a 5cm endometrioma. I am down for surgery for hysterectomy as I have adenomyosis and endo extraction. I've opted out of a bowel resection as the waiting list is longer
Hi I'm hoping someone can shed a bit of light on my pain. I have endo in lots of places in POD on ligaments and my bowel.I also have a 5cm endometrioma. I am down for surgery for hysterectomy as I have adenomyosis and endo extraction. I've opted out of a bowel resection as the waiting list is longer
Loveneige
in
Endometriosis UK
2 months ago
Catheters and travel
Hello everyoneI am a 64 year old woman, treated for rectal cancer with chemoradiotherapy with temporary stoma in 2009. I have had endless bladder and bowel issues since, and been hospitalized with numerous infections since the temporary stoma reversal - last infection of that type 2017, but now lots
Hello everyoneI am a 64 year old woman, treated for rectal cancer with chemoradiotherapy with temporary stoma in 2009. I have had endless bladder and bowel issues since, and been hospitalized with numerous infections since the temporary stoma reversal - last infection of that type 2017, but now lots
Hopeful-one
in
Pelvic Radiation Disease Association
2 months ago
Dense adhesions after 15 surgeries, + 2 rare medical conditions
At the age of 25, my life changed forever. After 4 years, 2 surgeries and no diagnosis, as to what the problems was, I eventually found out I had multiple intestinal lipomatosis and Ehlers Danlos Syndrome. Ileostomy formed 1996. 13 more surgeries have performed. Due to absorption problems, + major
At the age of 25, my life changed forever. After 4 years, 2 surgeries and no diagnosis, as to what the problems was, I eventually found out I had multiple intestinal lipomatosis and Ehlers Danlos Syndrome. Ileostomy formed 1996. 13 more surgeries have performed. Due to absorption problems, + major
Eegmetem
in
Pelvic Pain Support Network
2 months ago
FDG elements of PSMA scan
I had a FDG scan a few days ago . At the heart of my confusion is the function of FDG in giving a positive outcome to Pluvicto infusions. Is it a good thing to have lots of 'FDG Avid' showing up, or do you want those aspects of the scan to be as hidden as possible (so that the PSMA -Avid cells can be
I had a FDG scan a few days ago . At the heart of my confusion is the function of FDG in giving a positive outcome to Pluvicto infusions. Is it a good thing to have lots of 'FDG Avid' showing up, or do you want those aspects of the scan to be as hidden as possible (so that the PSMA -Avid cells can be
CrocodileShoes
in
Advanced Prostate Cancer
2 months ago
What is normal after surgery and what isn't
My husband had stoma surgery two weeks ago and got home a week later. Since coming home he seems to be deteriorating not improving. On the advice of his stoma nurse, we are going to see the GP to get bloods taken, etc this morning. However, is it normal to go off your food, be scared to eat in case
My husband had stoma surgery two weeks ago and got home a week later. Since coming home he seems to be deteriorating not improving. On the advice of his stoma nurse, we are going to see the GP to get bloods taken, etc this morning. However, is it normal to go off your food, be scared to eat in case
Suebedoo
in
Living with a Stoma
2 months ago
Stoma with Denosumab osteoporosis medication
Hi, I am posting the same thing in the osteoporosis forum and the stoma forum at the suggestion of my friend. My mum has had a stoma for over 50 years and is also on osteoporosis medication. Her doctor has suggested she moves to Denosumab which contains sorbitol and is a twice yearly injection. She
Hi, I am posting the same thing in the osteoporosis forum and the stoma forum at the suggestion of my friend. My mum has had a stoma for over 50 years and is also on osteoporosis medication. Her doctor has suggested she moves to Denosumab which contains sorbitol and is a twice yearly injection. She
Florrie2
in
Bone Health and Osteoporosis UK
2 months ago
Pale skin during flare ups
Does anyone else get a really washed out, pale almost grey skin during flare ups? My Mum often comments on me looking very pale but I caught sight of myself in the mirror yesterday and my eyes were dark underneath (despite having had a long nap), skin so pale with an almost greenish grey tint. Not very
Does anyone else get a really washed out, pale almost grey skin during flare ups? My Mum often comments on me looking very pale but I caught sight of myself in the mirror yesterday and my eyes were dark underneath (despite having had a long nap), skin so pale with an almost greenish grey tint. Not very
Lily1986
in
Endometriosis UK
2 months ago
Recently had stoma
I was diagnosed 2 years ago stage 4 high serious ovarian part bowel removed and 6 sessions chemo lived normal 18months then recurrence and more chemo then total hysterectomy omentom removed and shock when I woke I had stoma that is pernament finding it hard deal with and see consultant next week
I was diagnosed 2 years ago stage 4 high serious ovarian part bowel removed and 6 sessions chemo lived normal 18months then recurrence and more chemo then total hysterectomy omentom removed and shock when I woke I had stoma that is pernament finding it hard deal with and see consultant next week
PaumicB123
in
Living with a Stoma
2 months ago
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