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Mitoxantrone
Has anyone used this for chemo? What is the likelihood of it helping where Docetaxel and Cabazitaxel did not work at all? Thank you
Has anyone used this for chemo? What is the likelihood of it helping where Docetaxel and Cabazitaxel did not work at all? Thank you
spw1
in
Advanced Prostate Cancer
1 year ago
'Astonishing' Results: Skip Salvage Chemo, Go Straight to HSCT from ASH 2022 [For Refractory AML/Relapsed AML]
The remission-inducing arm consisted of cytarabine (3 g/m2 for younger patients or 1 g/m2 for patients over age 60) twice daily on days 1-3 plus 10
mitoxantrone
mg/m2 on days 3-5 and subsequent alloHCT.
The remission-inducing arm consisted of cytarabine (3 g/m2 for younger patients or 1 g/m2 for patients over age 60) twice daily on days 1-3 plus 10
mitoxantrone
mg/m2 on days 3-5 and subsequent alloHCT.
PhysAssist
in
MPN Voice
1 year ago
A critical review of Provenge. Your inputs welcomed?
The IMPACT placebo group excluded patients with visceral metastases [6% of
mitoxantrone
group in the study by Berry et al. (21)] and enrolled 75.4% of patients with favorable Gleason scores.
The IMPACT placebo group excluded patients with visceral metastases [6% of
mitoxantrone
group in the study by Berry et al. (21)] and enrolled 75.4% of patients with favorable Gleason scores.
GeorgeGlass
in
Advanced Prostate Cancer
1 year ago
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Any Exp with Inj Mitoxantrone, Side effects ??
Now, MO planned to start Inj
Mitoxantrone
. Can anyone help with the side effects or experience with Inj
Mitoxantrone
please ??
Now, MO planned to start Inj
Mitoxantrone
. Can anyone help with the side effects or experience with Inj
Mitoxantrone
please ??
pka21
in
Advanced Prostate Cancer
2 years ago
PSA is increasing after 11 cycle of Docetaxel, what should we do now ?
his PSA is rising again and it reached 2.47 ng/mL, we're now torn in between: 1) his MO recommended Xtandi, which costs ~ 1300$ and that's around 4.5X of his monthly income and the national health service in Egypt is not administering it. 2)instead, the national health service suggested a mix of
Mitoxantrone
his PSA is rising again and it reached 2.47 ng/mL, we're now torn in between: 1) his MO recommended Xtandi, which costs ~ 1300$ and that's around 4.5X of his monthly income and the national health service in Egypt is not administering it. 2)instead, the national health service suggested a mix of
Mitoxantrone
mgaa
in
Advanced Prostate Cancer
1 year ago
Third Jevtana/Carboplatin treatment completed. Total of 10 chemo treatments are now completed overall. Hoping for better results.
My oncologist indicates Other options including Provenge, xofigo ,
mitoxantrone
, clinical trials. I'm adding the possibility of Lu-177 to the mix. We're all in this together! Keep Going!
My oncologist indicates Other options including Provenge, xofigo ,
mitoxantrone
, clinical trials. I'm adding the possibility of Lu-177 to the mix. We're all in this together! Keep Going!
Mount_Rainier
in
Advanced Prostate Cancer
2 years ago
Decision time. Input welcome
of the
mitoxantrone
group (NEJM 351;15).
of the
mitoxantrone
group (NEJM 351;15).
Miccoman
in
Advanced Prostate Cancer
2 years ago
My Jevtana/Carboplatin results to date. Plus participation in Bipolar Androgen Therapy testing
We reviewed that past this regimen the use of medications such as
mitoxantrone
certainly are possible but the evidence for efficacy in this type of setting is quite limited. We reviewed that lutetium is still under review by the FDA and the timing for approval remains uncertain.
We reviewed that past this regimen the use of medications such as
mitoxantrone
certainly are possible but the evidence for efficacy in this type of setting is quite limited. We reviewed that lutetium is still under review by the FDA and the timing for approval remains uncertain.
Mount_Rainier
in
Advanced Prostate Cancer
2 years ago
Androgen Receptor [AR] Axis Therapies
Prednisone plus cabazitaxel or
mitoxantrone
for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet. 2010;376:1147-1154. Kantoff PW, Higano CS, Shore ND, et al.
Prednisone plus cabazitaxel or
mitoxantrone
for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet. 2010;376:1147-1154. Kantoff PW, Higano CS, Shore ND, et al.
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Opinions about chemotherapy. Running out of options
(A good oncologist): "We can also consider changing Carboplatin to Cyclophosphamide or
Mitoxantrone
.
(A good oncologist): "We can also consider changing Carboplatin to Cyclophosphamide or
Mitoxantrone
.
abmicro
in
Advanced Prostate Cancer
4 years ago
Next Steps after Cabazitaxel and Xtandi
My Oncologist, Alexander Menter in Denver, is giving me these options: "I think Xofigo, carboplatin, Taxotere,
mitoxantrone
, and revisiting trials are all good options. " Any suggestions?
My Oncologist, Alexander Menter in Denver, is giving me these options: "I think Xofigo, carboplatin, Taxotere,
mitoxantrone
, and revisiting trials are all good options. " Any suggestions?
tomtom9148
in
Advanced Prostate Cancer
4 years ago
Cabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer
In the prospective, noninferiority, phase 3 trial PROSELICA, a dose of 20 mg per square meter maintained at least 50% of the survival benefit of a dose of 25 mg per square meter (which had been compared with
mitoxantrone
in the TROPIC trial) and was associated with a lower incidence of adverse events
In the prospective, noninferiority, phase 3 trial PROSELICA, a dose of 20 mg per square meter maintained at least 50% of the survival benefit of a dose of 25 mg per square meter (which had been compared with
mitoxantrone
in the TROPIC trial) and was associated with a lower incidence of adverse events
pjoshea13
in
Advanced Prostate Cancer
5 years ago
Mitoxantrone Side Effects
Hello Has anyone out there been treated with
Mitoxantrone
chemotherapy an older drug?
Hello Has anyone out there been treated with
Mitoxantrone
chemotherapy an older drug?
sgrama
in
Advanced Prostate Cancer
5 years ago
Integrating Novel Targets and Precision Medicine Into Prostate Cancer Care—Part 1: The Non-Androgen–Targetable Pathways in Castration-Resist
This phase III study found an increased overall survival of 15.1 months in patients treated with cabazitaxel, compared with 12.7 months in men treated with
mitoxantrone
.[8] This was the first agent to demonstrate a survival benefit in docetaxel-refractory patients, and this trial led to the FDA approval
This phase III study found an increased overall survival of 15.1 months in patients treated with cabazitaxel, compared with 12.7 months in men treated with
mitoxantrone
.[8] This was the first agent to demonstrate a survival benefit in docetaxel-refractory patients, and this trial led to the FDA approval
JLS1
in
Advanced Prostate Cancer
5 years ago
No post for long time, here is my update.
I have been through: Lupron continuous from beginning, Strive, Docetaxal, Xtandi, Radium 223, Cabazitaxel,
Mitoxantrone
and other radiation treatments for pain etc. Throughout the years I’ve been admitted to the hospital for adjustment to my pain meds a few times.
I have been through: Lupron continuous from beginning, Strive, Docetaxal, Xtandi, Radium 223, Cabazitaxel,
Mitoxantrone
and other radiation treatments for pain etc. Throughout the years I’ve been admitted to the hospital for adjustment to my pain meds a few times.
Glsn10
in
Advanced Prostate Cancer
6 years ago
Need some help
but then i had three consecutive increases and Abiraterone has now been stopped with my PSA at 5 So my question is i have been offered treatment that i can not find much information on here in the UK and was after your thoughts, so 20 sessions of RT to the prostate BAT testosterone flood and drought
mitoxantrone
but then i had three consecutive increases and Abiraterone has now been stopped with my PSA at 5 So my question is i have been offered treatment that i can not find much information on here in the UK and was after your thoughts, so 20 sessions of RT to the prostate BAT testosterone flood and drought
mitoxantrone
siness
in
Advanced Prostate Cancer
6 years ago
Don’t know where I go from here.
I have been through: Lupron continuous from beginning, Strive, Docetaxal, Xtandi, Radium 223, Cabazitaxel,
Mitoxantrone
and other radiation treatments for pain etc. You can go back and look at my prior post for better timeline.
I have been through: Lupron continuous from beginning, Strive, Docetaxal, Xtandi, Radium 223, Cabazitaxel,
Mitoxantrone
and other radiation treatments for pain etc. You can go back and look at my prior post for better timeline.
Glsn10
in
Advanced Prostate Cancer
6 years ago
FIRSTANA Trial - Cabazitaxel 20/25 mg v. Docetaxel 75 mg
Abstract Purpose In patients with metastatic castration-resistant prostate cancer (mCRPC), overall survival (OS) is significantly improved with cabazitaxel versus
mitoxantrone
after prior docetaxel treatment.
Abstract Purpose In patients with metastatic castration-resistant prostate cancer (mCRPC), overall survival (OS) is significantly improved with cabazitaxel versus
mitoxantrone
after prior docetaxel treatment.
pjoshea13
in
Advanced Prostate Cancer
7 years ago
Anyone out there been on Mitoxantrone [Novantrone]??
Just trying to find someone else who has tried
Mitoxantrone
[Novantrone]. Thanks. Jeanne
Just trying to find someone else who has tried
Mitoxantrone
[Novantrone]. Thanks. Jeanne
jmatson
in
Advanced Prostate Cancer
7 years ago
Foods/Supplements-Vitamins: Vitamin A (Retinol, Retinoic Acid [RA], Beta Carotene)
Other trials, not considered because retinoic acid was not used as monotherapy: [B2c] (1999 - US - Phase I) 13-cis-retinoic acid, interferon alfa, and paclitaxel [B2d] (2003 - US - Phase I) 13- cis-retinoic acid, paclitaxel and interferon alpha [B2e] (2010 US - Phase II)
mitoxantrone
, estramustine
Other trials, not considered because retinoic acid was not used as monotherapy: [B2c] (1999 - US - Phase I) 13-cis-retinoic acid, interferon alfa, and paclitaxel [B2d] (2003 - US - Phase I) 13- cis-retinoic acid, paclitaxel and interferon alpha [B2e] (2010 US - Phase II)
mitoxantrone
, estramustine
pjoshea13
in
Advanced Prostate Cancer
8 years ago
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