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PALB2 genetic defect-Lynparza
I have PALB2 genetic defect. Just completed six cycles of Taxotere as part of triple therapy (chemo, Nubeqa and ADT) for about 20 Mets (PSMA scan) mostly skeletal (no organs). Only four Mets still lit up on PSMA scan after four cycles of chemo/Lupron/Nubeqa. Next PSMA scan in Jan. 2024. Oncologist recommends
I have PALB2 genetic defect. Just completed six cycles of Taxotere as part of triple therapy (chemo, Nubeqa and ADT) for about 20 Mets (PSMA scan) mostly skeletal (no organs). Only four Mets still lit up on PSMA scan after four cycles of chemo/Lupron/Nubeqa. Next PSMA scan in Jan. 2024. Oncologist recommends
Azores1
in
Advanced Prostate Cancer
7 months ago
jaundice
Just a quick question. Is Jaundice always present in worsening of Liver/cholestatic problems?
Just a quick question. Is Jaundice always present in worsening of Liver/cholestatic problems?
MrMidnight2021
in
British Liver Trust
7 months ago
Bile Acid Diarrhoea
I have this condition and take colestyramine daily which controls it well. I recently asked my GP to have my fat soluble vitamins checked (A,D and K, I believe) in a blood test as this has not been checked in a long time. The email! came back saying there was no indication for this. The literature
I have this condition and take colestyramine daily which controls it well. I recently asked my GP to have my fat soluble vitamins checked (A,D and K, I believe) in a blood test as this has not been checked in a long time. The email! came back saying there was no indication for this. The literature
Whitesugar
in
IBS Network
4 months ago
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Palliative care, does it still exist?
I saw a consultant , for the first time since well before lockdown, on the 14th September. I'd never met him before but he was really great. He'd obviously read my notes as he asked about all my conditions, osteoporosis, swollen legs etc. He said my lung condition is now too far gone to put me through
I saw a consultant , for the first time since well before lockdown, on the 14th September. I'd never met him before but he was really great. He'd obviously read my notes as he asked about all my conditions, osteoporosis, swollen legs etc. He said my lung condition is now too far gone to put me through
wheezyof
in
Lung Conditions Community Forum
7 months ago
Amlodipine
Hello everyone, I realise this may not be relevant on this site, but I’ve been struggling with palpitations and anxiety for a few months. I had put this down (see previous posts) to the adrenals not wanting to play ball after their nice long holiday, due to Pred, but it suddenly dawned on me that this
Hello everyone, I realise this may not be relevant on this site, but I’ve been struggling with palpitations and anxiety for a few months. I had put this down (see previous posts) to the adrenals not wanting to play ball after their nice long holiday, due to Pred, but it suddenly dawned on me that this
Mrsd12f
in
PMRGCAuk
7 months ago
had bladder repair in september went ok but now
morning every one, i had my bladder repair op in september then i had a water infection . and i take different meds off the doctor to clear it . it clear after i have a7 day caurse . then its back again . since iv had the bladder op i feel like my bladder gets full more ofter and no materr how often
morning every one, i had my bladder repair op in september then i had a water infection . and i take different meds off the doctor to clear it . it clear after i have a7 day caurse . then its back again . since iv had the bladder op i feel like my bladder gets full more ofter and no materr how often
Mrshappyme
in
Pelvic Pain Support Network
1 year ago
Options for Recurrent PCa w/ RT Initial Therapy
Looking for options with intent to [u]cure[/u] if recurrence is limited to prostate only, pending PET-PSMA. Have read about these options: Prostatectomy/Brachytherapy/Cystoprostatectomy/Cryotherapy Anybody have any knowledge or studies that might suggest a direction? Still hoping for the possibility
Looking for options with intent to [u]cure[/u] if recurrence is limited to prostate only, pending PET-PSMA. Have read about these options: Prostatectomy/Brachytherapy/Cystoprostatectomy/Cryotherapy Anybody have any knowledge or studies that might suggest a direction? Still hoping for the possibility
Researcher50
in
Advanced Prostate Cancer
11 months ago
Simvastatin v Atorvastatin
Just had a conversation with my Surgery employed Pharmacist. she asked me if I would object to switching from Simvastatin to Atorvastatin as the Simvastatin was rather an old drug. I was put on it around 2007. I told her to go ahead ... no problems. The following quote is what I found during an ultra
Just had a conversation with my Surgery employed Pharmacist. she asked me if I would object to switching from Simvastatin to Atorvastatin as the Simvastatin was rather an old drug. I was put on it around 2007. I told her to go ahead ... no problems. The following quote is what I found during an ultra
BenHall1
in
Atrial Fibrillation Support
7 months ago
cochlear implants
Hello , I have been away from the tInnitus group but thought I would just put a message out there . I have had really bad tinnitus for 7 years now as a result of a grommet being put in my ear. I have had 8 operations on my ear …a grommet put in and out twice , a stapadectomy ( bone removed) and I am
Hello , I have been away from the tInnitus group but thought I would just put a message out there . I have had really bad tinnitus for 7 years now as a result of a grommet being put in my ear. I have had 8 operations on my ear …a grommet put in and out twice , a stapadectomy ( bone removed) and I am
1Dar
in
Tinnitus UK
7 months ago
High ferritin and high TSH
I have Bile Acid Malabsorption, does anyone know if this affects thyroid symptoms? Ferritin 291, TSH 159 Thanks
I have Bile Acid Malabsorption, does anyone know if this affects thyroid symptoms? Ferritin 291, TSH 159 Thanks
Dylan555
in
Thyroid UK
7 months ago
Probiotics
Hi I've had ibs c for so so long. Over the years I've learnt what does and doesn't suit me with my diet. I'm now mainly ok in comparison but also as I've got older I get bouts of diarrhea which I know are from eating foods that don't agree with me. I had a fair amount of cream cake over Christmas I'm
Hi I've had ibs c for so so long. Over the years I've learnt what does and doesn't suit me with my diet. I'm now mainly ok in comparison but also as I've got older I get bouts of diarrhea which I know are from eating foods that don't agree with me. I had a fair amount of cream cake over Christmas I'm
Gizmo6
in
IBS Network
4 months ago
Aortitis
I was diagnosed with non cranial Giant Cell Arteritis in September last year. So far I haven't managed to find anyone else with this condition because most people have the temporal version with the headaches.Mine is Aortitis which apparently is rare. I'd love to share experiences with someone else
I was diagnosed with non cranial Giant Cell Arteritis in September last year. So far I haven't managed to find anyone else with this condition because most people have the temporal version with the headaches.Mine is Aortitis which apparently is rare. I'd love to share experiences with someone else
Dance62
in
PMRGCAuk
3 months ago
So Yet Another Follow Up - Starting I think 2020 - Bizzar,
Well those who know me will know not long ago I had scan including PET Scan for suspected Lung Cancer or TB. In the end was put down to new scarring. Many of you will know in 2020 I got Bladder Cancer symptoms - I was diagnosed with Bladder Cancer in site a year later and was treated with a TURBT to
Well those who know me will know not long ago I had scan including PET Scan for suspected Lung Cancer or TB. In the end was put down to new scarring. Many of you will know in 2020 I got Bladder Cancer symptoms - I was diagnosed with Bladder Cancer in site a year later and was treated with a TURBT to
Ern007
in
Lung Conditions Community Forum
1 year ago
Metastic clear cell...
Hi, everyone. How are you? I just came back from my clinic appointment and was told news I didn't really want to hear. It spread again to one of lymph nodes near right kidney. That made sense why I had a pain there. I was on single dose of celarsertib for a few years. Now it's discontinued. My consultant
Hi, everyone. How are you? I just came back from my clinic appointment and was told news I didn't really want to hear. It spread again to one of lymph nodes near right kidney. That made sense why I had a pain there. I was on single dose of celarsertib for a few years. Now it's discontinued. My consultant
carrotmunch5
in
My Ovacome
7 months ago
APS or sticky blood syndrome
having suffered from PA for 20-30 years was sort of resigned to my fate of suffering from painful arms /hands and general lack of energy , anyway I then develop a Deep Vein Thrombosis in my calf muscle which I am advised could be caused by APS - also an auto immune response - was give Apixaban for
having suffered from PA for 20-30 years was sort of resigned to my fate of suffering from painful arms /hands and general lack of energy , anyway I then develop a Deep Vein Thrombosis in my calf muscle which I am advised could be caused by APS - also an auto immune response - was give Apixaban for
pj1954
in
Pernicious Anaemia Society
7 months ago
Somatic tinnitus
Hi All, I have had T for 7 months. It isn’t hearing related. However, as I have been on this journey, I have noticed that I have the T constant 24/7 that often changes with random spikes. However, I am also experiencing somatic T that I wasn’t fully aware of before. I was diagnosed with TMD and have
Hi All, I have had T for 7 months. It isn’t hearing related. However, as I have been on this journey, I have noticed that I have the T constant 24/7 that often changes with random spikes. However, I am also experiencing somatic T that I wasn’t fully aware of before. I was diagnosed with TMD and have
Sassyjax1
in
Tinnitus UK
7 months ago
Prednisolene
Good Morning . I was diagnosed with Rheumatoid Arthritis nearly three years ago . My private consultant started me on 15 mg of steroids for a month followed by a slow taper along with 15 mg methotrexate . I had a really good 18 months playing tennis and generally feeling really well with CRP around
Good Morning . I was diagnosed with Rheumatoid Arthritis nearly three years ago . My private consultant started me on 15 mg of steroids for a month followed by a slow taper along with 15 mg methotrexate . I had a really good 18 months playing tennis and generally feeling really well with CRP around
Portopetro
in
PMRGCAuk
7 months ago
piles and constipation
hi I’m 24 weeks and 3 days pregnant and have got piles all I’m doing is drinking fluid sticking to fruit veg and hi fibre foods I also have 4 other children I’m using paracetamol and laxative s along with cream I’ve had them 6 days now it really really hurts any advice welcome thanks for reading xx
hi I’m 24 weeks and 3 days pregnant and have got piles all I’m doing is drinking fluid sticking to fruit veg and hi fibre foods I also have 4 other children I’m using paracetamol and laxative s along with cream I’ve had them 6 days now it really really hurts any advice welcome thanks for reading xx
Loulou123886
in
Pregnancy and Parenting Support
4 months ago
Diagnosis of Sigmoid volvulus 3 weeks ago and an emergency operation via colon righted it temporarily.
I am recovering slowly from the shock of the above diagnosis. The surgeon said he will have to do a major abdominal operation (which he is reluctant to do whilst I am on Prednisolone, I was on 6 mg 3 weeks ago but now on 5mg) as healing and infection could be post operative problems. So I saw my Rheumatologist
I am recovering slowly from the shock of the above diagnosis. The surgeon said he will have to do a major abdominal operation (which he is reluctant to do whilst I am on Prednisolone, I was on 6 mg 3 weeks ago but now on 5mg) as healing and infection could be post operative problems. So I saw my Rheumatologist
Helag
in
PMRGCAuk
1 year ago
anal leakage and constipation
my husband has aggressive metastatic prostate cancer Gleason 8 with mets to lymph nodes, bladder, and pelvic bones and hips. He is scheduled to start triplet therapy in the next 2 weeks. Last week he underwent a TURP procedure in hopes to get rid of the catheter which he had for over 2 months. Unfortunately
my husband has aggressive metastatic prostate cancer Gleason 8 with mets to lymph nodes, bladder, and pelvic bones and hips. He is scheduled to start triplet therapy in the next 2 weeks. Last week he underwent a TURP procedure in hopes to get rid of the catheter which he had for over 2 months. Unfortunately
Jojoteacher
in
Advanced Prostate Cancer
11 months ago
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