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Mortality Probability after first PSA rise vs non-castrate testosterone levels (low vs Normal)
Here's a plot from Atkins (2018) that shows the Percent risk of Prostate Cancer-specific Mortality versus time following a first PSA failure, for two different non-castrate testosterone levels (Low-T and Normal-T). The low testosterone levels are: median = 162, range = 120-236 ng/dL. Normal T is 400
Here's a plot from Atkins (2018) that shows the Percent risk of Prostate Cancer-specific Mortality versus time following a first PSA failure, for two different non-castrate testosterone levels (Low-T and Normal-T). The low testosterone levels are: median = 162, range = 120-236 ng/dL. Normal T is 400
janebob99
in
Advanced Prostate Cancer
3 months ago
Can anyone help me please.....
Hi, can anyone help me with these test results please.I have Graves disease, Anemia, pernicious anemia, vitamin D deficiency and various other ailments, but I have been in remission from my graves for at least 5 years. I have been symptomatic a few times but it seems to correct itself, however my hubby
Hi, can anyone help me with these test results please.I have Graves disease, Anemia, pernicious anemia, vitamin D deficiency and various other ailments, but I have been in remission from my graves for at least 5 years. I have been symptomatic a few times but it seems to correct itself, however my hubby
Loza73
in
Thyroid UK
3 months ago
First PSA after RARP
My dad had RARP on Jan 19,2024. Gleason 8(4+4) PSA 12, clean PSMA pet scan before surgery. Path report had no LN SVI or EPE but PNI and 50 percent prostate involvement. PSA today 6 weeks post surgery came out to .09. What should we do next? Age 73. Tall_Allen Please advice. Thanks a lot for your help
My dad had RARP on Jan 19,2024. Gleason 8(4+4) PSA 12, clean PSMA pet scan before surgery. Path report had no LN SVI or EPE but PNI and 50 percent prostate involvement. PSA today 6 weeks post surgery came out to .09. What should we do next? Age 73. Tall_Allen Please advice. Thanks a lot for your help
Pca2024
in
Advanced Prostate Cancer
3 months ago
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PSA reduction after Estrogen Patch Therapy
Here's a revised plot of PSA reduction due to castration from Estrogen Patch therapy. The previous version had the wrong time scale. That has been corrected in this version. The total time is 3 months, after which the PSA and testosterone both flatten out versus time. I've also added the reference
Here's a revised plot of PSA reduction due to castration from Estrogen Patch therapy. The previous version had the wrong time scale. That has been corrected in this version. The total time is 3 months, after which the PSA and testosterone both flatten out versus time. I've also added the reference
janebob99
in
Advanced Prostate Cancer
3 months ago
Dad's PSA risen from 0.01 to 0.05 in 2 months, 2 years post SRT. Any chance that there is no further progression?
PSA has risen 3 times in a row. I understand the figure is still low, but is this a definite indication that it will progress, or is there a chance that PSA can stabilize or fluctuate and not progress further? Things have been difficult in the family, I am hoping for a miracle that he had a curative
PSA has risen 3 times in a row. I understand the figure is still low, but is this a definite indication that it will progress, or is there a chance that PSA can stabilize or fluctuate and not progress further? Things have been difficult in the family, I am hoping for a miracle that he had a curative
MsBoBo
in
Advanced Prostate Cancer
3 months ago
Return of the Duck. The Saga Continues.......
Good morning guys and gals.Hope everyone is as well as they can be. Well, here's the promised update from a couple of years ago but to be fair, nothing much had happened on the heart surgery front, I'd been in nsr and I have still been contributing replies. Settle down with a strong drink of choice,
Good morning guys and gals.Hope everyone is as well as they can be. Well, here's the promised update from a couple of years ago but to be fair, nothing much had happened on the heart surgery front, I'd been in nsr and I have still been contributing replies. Settle down with a strong drink of choice,
Ducky2003
in
Atrial Fibrillation Support
1 month ago
PSA drop with decreasing Testosterone after Estrogen Patch Therapy
Here's a plot that I made from data taken from the PATCH estrogen patch therapy study. It plots the % reduction in PSA from baseline (100%) at time = 0 as a function of testosterone levels over a period of 4 weeks. As you know, estrogen effectively castrates men, causing a drop in testosterone over
Here's a plot that I made from data taken from the PATCH estrogen patch therapy study. It plots the % reduction in PSA from baseline (100%) at time = 0 as a function of testosterone levels over a period of 4 weeks. As you know, estrogen effectively castrates men, causing a drop in testosterone over
janebob99
in
Advanced Prostate Cancer
3 months ago
PSA spiked from .6 to 8.0 in 3 months
The blood test corroborates the MRI that shows spread. I am talking with Dr Goodman in the AM. Am I doomed? My PSA has never been 8. before
The blood test corroborates the MRI that shows spread. I am talking with Dr Goodman in the AM. Am I doomed? My PSA has never been 8. before
crony
in
Advanced Prostate Cancer
3 months ago
Low DHEA Results and possible low cortisol
Hi, just wondering if anyone knows anything about low dhea/ cortisol and can shine some light on my results? They were done by blood draw but I have ordered the saliva cortisol test. DHEA Sulphate X 0.8 umol/L Please note change of reference range 23 Oct 2022 (Range: 1.65 - 9.15) Cortisol 261.0
Hi, just wondering if anyone knows anything about low dhea/ cortisol and can shine some light on my results? They were done by blood draw but I have ordered the saliva cortisol test. DHEA Sulphate X 0.8 umol/L Please note change of reference range 23 Oct 2022 (Range: 1.65 - 9.15) Cortisol 261.0
jenny876
in
Thyroid UK
3 months ago
Mindfulness and Kidney Disease
Dealing with a chronic illness like kidney disease or kidney failure can take a toll on a person’s mental health. Gary Petingola, a social worker certified to teach mindfulness-based stress reduction, is here to introduce you to a simple practice to help you relax. Learn what mindfulness is, its benefits
Dealing with a chronic illness like kidney disease or kidney failure can take a toll on a person’s mental health. Gary Petingola, a social worker certified to teach mindfulness-based stress reduction, is here to introduce you to a simple practice to help you relax. Learn what mindfulness is, its benefits
JackieJ_NKF
Partner
in
Kidney Dialysis
3 months ago
A useful option-gastro resistant empty capsules
a post yesterday reminded me to tell you all that I’ve been taking my preds in gastro resistant empty capsules for a couple of months now. This means I can take them without food around midnight. But I have also taken them at 11pm ish and not noticed any difference. I asked a gp if I should still take
a post yesterday reminded me to tell you all that I’ve been taking my preds in gastro resistant empty capsules for a couple of months now. This means I can take them without food around midnight. But I have also taken them at 11pm ish and not noticed any difference. I asked a gp if I should still take
Freshairfiend
in
PMRGCAuk
3 months ago
Pain Management
Dear All can anyone help. Diagnosed with stage 1V advanced metastatic prostate cancer December 2022. 6 sessions of Chemo, then Firmagon and Nubeqa PSA was 349 now about 1 but has been increasing. Cancer was in most bones but no organs - primarily pelvis and hips - have had radiation treatment but still
Dear All can anyone help. Diagnosed with stage 1V advanced metastatic prostate cancer December 2022. 6 sessions of Chemo, then Firmagon and Nubeqa PSA was 349 now about 1 but has been increasing. Cancer was in most bones but no organs - primarily pelvis and hips - have had radiation treatment but still
Nyon
in
Advanced Prostate Cancer
3 months ago
Beaconthecat
Diagnosed last April thru a lymph node biopsy....results SLL...currently on W&W...a few more nodes have emerged but feel good, no symptoms, exercise hard and just living life...
Diagnosed last April thru a lymph node biopsy....results SLL...currently on W&W...a few more nodes have emerged but feel good, no symptoms, exercise hard and just living life...
Beaconthecat
in
CLL Support
3 months ago
Some Reference Material - NECP/SCCP
-----
I am constantly updating this post as I come across additional relevant material.
----- Emerging Insights in Small-Cell Carcinoma of the Genitourinary Tract: From Diagnosis to Novel Therapeutic Horizons, 2024 https://ascopubs.org/doi/10.1200/EDBK_430336#:~:text=Small%2Dcell%20carcinoma
-----
I am constantly updating this post as I come across additional relevant material.
----- Emerging Insights in Small-Cell Carcinoma of the Genitourinary Tract: From Diagnosis to Novel Therapeutic Horizons, 2024 https://ascopubs.org/doi/10.1200/EDBK_430336#:~:text=Small%2Dcell%20carcinoma
skiingfiend
in
Advanced Prostate Cancer
3 months ago
all aspects of liver research
In the article that was posted below, I know this is not something many of us want to face at anytime in our PBC journey. This is, however, a reality for some of us who did progress to this point in our disease. I have to find some real hope that researchers are working on all aspects of PBC. There are
In the article that was posted below, I know this is not something many of us want to face at anytime in our PBC journey. This is, however, a reality for some of us who did progress to this point in our disease. I have to find some real hope that researchers are working on all aspects of PBC. There are
DonnaBoll
Administrator
in
PBC Foundation
3 months ago
Travel
My husband has decompensated alcohol related liver disease with ascites, abstinent for 7 months. We would like to get to Germany to see his family for a month in our motorhome and wondered if a) anyone has travelled abroad with this condition and b) if anyone has experience of the insurance companies
My husband has decompensated alcohol related liver disease with ascites, abstinent for 7 months. We would like to get to Germany to see his family for a month in our motorhome and wondered if a) anyone has travelled abroad with this condition and b) if anyone has experience of the insurance companies
Breakfastbabe
in
British Liver Trust
3 months ago
Bloating
Hi....I've battled with IBS for many years and following endoscopy and gastroscopy I was diagnosed with a lazy stomach. Dietary controls and careful eating seemed to keep things under control with minimal 'episodes' of wind, bloating and diarrhea. Fast forward a few years and following a prolonged course
Hi....I've battled with IBS for many years and following endoscopy and gastroscopy I was diagnosed with a lazy stomach. Dietary controls and careful eating seemed to keep things under control with minimal 'episodes' of wind, bloating and diarrhea. Fast forward a few years and following a prolonged course
Sardinesagain
in
IBS Network
3 months ago
Testosterone and PCa risk - 3
Here's a plot showing the Odds Ratio for having either Intermediate Risk PCa or high-risk PCa, as a function of baseline testosterone levels. The Odds Ratio tells the likelihood of getting PCa, compared to a reference value of 1. So, for example, for the lower plot (high risk), a testosterone level
Here's a plot showing the Odds Ratio for having either Intermediate Risk PCa or high-risk PCa, as a function of baseline testosterone levels. The Odds Ratio tells the likelihood of getting PCa, compared to a reference value of 1. So, for example, for the lower plot (high risk), a testosterone level
janebob99
in
Advanced Prostate Cancer
3 months ago
Testosterone and PCa risk - 2
This plot shows a Kaplan-Mier Prostate Cancer Mortality Survival plot for three different levels of baseline testosterone: Low-T, IntermediateT, and Normal-T. The best survival is for men with Normal testosterone levels at baseline, and the worst survival is for men with low-T. REF: www.spandidos-publications.com
This plot shows a Kaplan-Mier Prostate Cancer Mortality Survival plot for three different levels of baseline testosterone: Low-T, IntermediateT, and Normal-T. The best survival is for men with Normal testosterone levels at baseline, and the worst survival is for men with low-T. REF: www.spandidos-publications.com
janebob99
in
Advanced Prostate Cancer
3 months ago
Testosterone Levels and Prostate Cancer Risk - 1
This plot shows the association of baseline testosterone levels with PCa aggressiveness. For example, if you have low aggressive PCA, your testosterone is likely to be Normal. But, if you have metastatic PCa, your testosterone is likely to be very Low. This shows that having normal testosterone
This plot shows the association of baseline testosterone levels with PCa aggressiveness. For example, if you have low aggressive PCA, your testosterone is likely to be Normal. But, if you have metastatic PCa, your testosterone is likely to be very Low. This shows that having normal testosterone
janebob99
in
Advanced Prostate Cancer
3 months ago
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