Hi, the week before Christmas, I had a call from a consultant to say that the CT scan I had had, shown I have (his words), a lesion on my brain. A Meningioma. I asked him to spell it, as i didn't know what it was. He then said i now need an MRI which he was then requesting. He asked me questions regarding the MRI, said he would send me forms to request a blood test, said it would be the new year now, wished me a happy Christmas, and went. It wasn't until I looked it up that it hit me!!! Does anyone have experience of this? And are they related to Lupus, and Autoimmune etc.? I am a bit on edge about it all. Thankyou for reading my post. x
Meningioma : Hi, the week before Christmas, I had a... - LUPUS UK
Meningioma
Info on Meningioma:
Oh I am so very sorry. Of course you are anxious it was irresponsible of your Doctor to just drop that news and then just leave you to worry. I have no experience with it but I wish you the very best. Please let us know how you get on xxx
Yes I have. I was told my meningioma was nothing to do with my UCTD and that lots of people have them without even knowing. They will do an MRI scan, probably with a contrast dye, to be able to give you a more in depth report on it. Try not to worry, easier said than done I know, here if you need a chat xx
Merry Christmas to all of you,
In my opinion, it could have any relationship because Folate metabolism plays an important role in carcinogenesis or development of primary brain tumors. In particular, genotypes associated with increased 5,10-methylenetetrahydrofolate levels are associated with elevated risk.
Also the relationship between risk of meningioma and exposure to ionizing radiation is also well known and apparently also to Oxidative stress.
Bibliography
Bethke L, Webb E, Murray A, Schoemaker M, Feychting M, Lönn S, et al. Functional polymorphisms in folate metabolism genes influence the risk of meningioma and glioma. Cancer Epidemiol Biomarkers Prev. 2008;17(5):1195–202.
ncbi.nlm.nih.gov/pubmed/184...
ncbi.nlm.nih.gov/pubmed/182...
ncbi.nlm.nih.gov/pubmed/186...
It seems that hereditary factors also play an important role in meningioma development, as well as environmental and hormonal factors which make the disease difficult to prevent.