Search
Search
About
Log in
Join
Experiences with
Enzalutamide
Posts
Communities
786 public posts
Filter results
What first?: Provenge or Nubeqa?
Recently approved agents include abiraterone acetate and
enzalutamide
with TAK-700 (orteronel) and lyase inhibitors rapidly approaching in the development pipeline..."
Recently approved agents include abiraterone acetate and
enzalutamide
with TAK-700 (orteronel) and lyase inhibitors rapidly approaching in the development pipeline..."
GeorgeGlass
in
Advanced Prostate Cancer
1 year ago
Enzalutamide or abiraterone
What is the difference between these two drugs. Which one should I use. I know this was discussed in a post recently. My Oncologist would like me to start with one of these. I asked him this question and said abiraterone has less fatigue side effects. I will need to get blood work done every two weeks
What is the difference between these two drugs. Which one should I use. I know this was discussed in a post recently. My Oncologist would like me to start with one of these. I asked him this question and said abiraterone has less fatigue side effects. I will need to get blood work done every two weeks
Islandboy2021
in
Advanced Prostate Cancer
2 years ago
BATMAN
Post-BAT, the PSA50 and PSA90 responses to abiraterone or
enzalutamide
were 94.4% and 66.7%, respectively and median PFS was 20.6 months. Patients with peak PSA level of ≥9 ng/ml after BAT had median PFS of 20.6 months versus NR for those having PSA < 9 ng/ml (HR: 0.122, p < 0.001).
Post-BAT, the PSA50 and PSA90 responses to abiraterone or
enzalutamide
were 94.4% and 66.7%, respectively and median PFS was 20.6 months. Patients with peak PSA level of ≥9 ng/ml after BAT had median PFS of 20.6 months versus NR for those having PSA < 9 ng/ml (HR: 0.122, p < 0.001).
pca2004
in
Fight Prostate Cancer
1 year ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
EMBARK trial results reported
[/i] https://www.pfizer.com/news/press-release/press-release-detail/phase-3-study-shows-xtandir-
enzalutamide
-plus-leuprolide
[/i] https://www.pfizer.com/news/press-release/press-release-detail/phase-3-study-shows-xtandir-
enzalutamide
-plus-leuprolide
GP24
in
Advanced Prostate Cancer
1 year ago
Intracrinology-Revisited and Prostate Cancer
Moreover, indomethacin was found to surmount abiraterone and
enzalutamide
drug resistance in xenograft models over expressing AKR1C3 (71,72). These observations lead to the development of ASP9521 by Astellas.
Moreover, indomethacin was found to surmount abiraterone and
enzalutamide
drug resistance in xenograft models over expressing AKR1C3 (71,72). These observations lead to the development of ASP9521 by Astellas.
KocoPr
in
Fight Prostate Cancer
1 year ago
Advice Please
Enzalutamide
failed after about 6 months. Started docetaxel on Aug 10/22. After 4 cycles, bone scan results, received today, indicate a mixed pattern of response i.e., while many lesions have improved there is also progression in certain lesions as well as new lesions.
Enzalutamide
failed after about 6 months. Started docetaxel on Aug 10/22. After 4 cycles, bone scan results, received today, indicate a mixed pattern of response i.e., while many lesions have improved there is also progression in certain lesions as well as new lesions.
Univs
in
Advanced Prostate Cancer
2 years ago
Keynote trial of Pembrolizumab + Enz+ ADT discontinued
Disappointing results of trial https://www.businesswire.com/news/home/20230124006084/en/Merck-Announces-KEYNOTE-991-Trial-Evaluating-KEYTRUDA%C2%AE-pembrolizumab-Plus-
Enzalutamide
-and-Androgen-Deprivation-Therapy-in-Patients-With-Metastatic-Hormone-Sensitive-Prostate-Cancer-to-Stop-for-Futility
Disappointing results of trial https://www.businesswire.com/news/home/20230124006084/en/Merck-Announces-KEYNOTE-991-Trial-Evaluating-KEYTRUDA%C2%AE-pembrolizumab-Plus-
Enzalutamide
-and-Androgen-Deprivation-Therapy-in-Patients-With-Metastatic-Hormone-Sensitive-Prostate-Cancer-to-Stop-for-Futility
Fightinghard
in
Advanced Prostate Cancer
1 year ago
Wa-ah!
I am to continue with my current medication,
enzalutamide
, though at a stronger dose> I am to take morphine to counteract the worst side effect, muscle pain. This will also help with the ache I have in my pelvis, where I had radiation.
I am to continue with my current medication,
enzalutamide
, though at a stronger dose> I am to take morphine to counteract the worst side effect, muscle pain. This will also help with the ache I have in my pelvis, where I had radiation.
BrentW
in
Advanced Prostate Cancer
2 years ago
Xtandi (enzalutamide) alone is superior to ADT alone at preventing metastases in "high-risk" recurrent men
https://www.pfizer.com/news/press-release/press-release-detail/phase-3-study-shows-xtandir-
enzalutamide
-plus-leuprolide
https://www.pfizer.com/news/press-release/press-release-detail/phase-3-study-shows-xtandir-
enzalutamide
-plus-leuprolide
Tall_Allen
in
Advanced Prostate Cancer
1 year ago
Xtandi Enzalutamide
My husband was on Xtandi. It was not effective, so he stopped taking it. However, he has a bottle of the tablets that are still in the sealed box (Exp 8/24). He received them through his insurance so the cost to him was minimal, but it is a very expensive drug if one does not have insurance. We tried
My husband was on Xtandi. It was not effective, so he stopped taking it. However, he has a bottle of the tablets that are still in the sealed box (Exp 8/24). He received them through his insurance so the cost to him was minimal, but it is a very expensive drug if one does not have insurance. We tried
Epikos
in
Advanced Prostate Cancer
2 years ago
After BCR and PSA Return: An Update on My Treatment Path
At the time, I gathered a few second opinions and most top research hospital doctors just recommended intermittent ADT with an anti-androgen (
Enzalutamide
). I chose the heavier path "triple play" (+SBRT and chemo) for a couple of reasons.
At the time, I gathered a few second opinions and most top research hospital doctors just recommended intermittent ADT with an anti-androgen (
Enzalutamide
). I chose the heavier path "triple play" (+SBRT and chemo) for a couple of reasons.
PGDuan
in
Advanced Prostate Cancer
9 months ago
What a long strange road it's been.
They were all scratching their heads over that and also had no idea why it created a liquid filled cyst the size of a mango. ( I saw the video of cutting into it and liquid spilling out all over. ) They added Xtandi (
enzalutamide
) to the ADT regimen, as the lupron shots weren't stopping the cancer
They were all scratching their heads over that and also had no idea why it created a liquid filled cyst the size of a mango. ( I saw the video of cutting into it and liquid spilling out all over. ) They added Xtandi (
enzalutamide
) to the ADT regimen, as the lupron shots weren't stopping the cancer
bcskibdy
in
Prostate Cancer And Gay Men
7 months ago
Radium 223 instead of enzalutamide
Apparently they are becoming more active so the
enzalutamide
hasn’t held them off. I wanted to check what people in this forum thought of this as I am concerned about him coming off
enzalutamide
but the doc doesn’t seem to be?
Apparently they are becoming more active so the
enzalutamide
hasn’t held them off. I wanted to check what people in this forum thought of this as I am concerned about him coming off
enzalutamide
but the doc doesn’t seem to be?
SC19
in
Advanced Prostate Cancer
2 years ago
Novel AR-Targeted Therapies for mHSPC: Which One to Choose
mHSPC - https://www.onclive.com/view/novel-ar-targeted-therapies-for-metastatic-hormone-sensitive-prostate-cancer-which-one-to-choose A comment stood out for me that many may already be aware of but worth highlighting anyway: [i]... an analysis of the ARCHES study found that many patients receiving
enzalutamide
mHSPC - https://www.onclive.com/view/novel-ar-targeted-therapies-for-metastatic-hormone-sensitive-prostate-cancer-which-one-to-choose A comment stood out for me that many may already be aware of but worth highlighting anyway: [i]... an analysis of the ARCHES study found that many patients receiving
enzalutamide
Benkaymel
in
Advanced Prostate Cancer
2 years ago
Enzalutamide just keeps giving and giving: Hot heels
The
enzalutamide
I am taking has made the muscles in my right arm rigid, so it is far too uncomfortable to sleep on that side despite taking the opioid Longtec (40 mg at night). Nor can I sleep on my left side.
The
enzalutamide
I am taking has made the muscles in my right arm rigid, so it is far too uncomfortable to sleep on that side despite taking the opioid Longtec (40 mg at night). Nor can I sleep on my left side.
BrentW
in
Advanced Prostate Cancer
1 year ago
Current PCa treatment options in the UK do NOT include Triplet Therapy!
They strongly recommend that I start with Prostap +
Enzalutamide
. I referred to various clinical trials and they say they are aware of them but that is the treatment that is currently available and I should check out websites like Macmillan and NHS to confirm this.
They strongly recommend that I start with Prostap +
Enzalutamide
. I referred to various clinical trials and they say they are aware of them but that is the treatment that is currently available and I should check out websites like Macmillan and NHS to confirm this.
Benkaymel
in
Advanced Prostate Cancer
2 years ago
Splash Study (Lutetium+Enzalutamide trial)
My MO is proposing to switch me to Splash Phase 3 arm ->Lutetium PSMA & switch current Zytiga hormonal therapy to
Enzalutamide
. I could not find much info about the results of the Ph1/2. Here is the link https://www.splashtrial.com/
My MO is proposing to switch me to Splash Phase 3 arm ->Lutetium PSMA & switch current Zytiga hormonal therapy to
Enzalutamide
. I could not find much info about the results of the Ph1/2. Here is the link https://www.splashtrial.com/
MikeMartin
in
Advanced Prostate Cancer
2 years ago
Not so sure I should be on Erleada
Erleada has some harsh side effects, appears to me harsher than Darolutamide or
Enzalutamide
. I plan to follow my oncologist orders until I meet at the end of November.
Erleada has some harsh side effects, appears to me harsher than Darolutamide or
Enzalutamide
. I plan to follow my oncologist orders until I meet at the end of November.
swwags
in
Advanced Prostate Cancer
2 years ago
Running out of road....
Then when it escaped the lymph nodes, I was place on shots+
enzalutamide
/Xtandi. I hate that drug, so I was almost relieved that PSA started rising again : 1.7 to 3.3 and evidence of small mets in spine. Because I had to work in Australia for 2 months we did nothing (except I added Propanalol.
Then when it escaped the lymph nodes, I was place on shots+
enzalutamide
/Xtandi. I hate that drug, so I was almost relieved that PSA started rising again : 1.7 to 3.3 and evidence of small mets in spine. Because I had to work in Australia for 2 months we did nothing (except I added Propanalol.
CrocodileShoes
in
Advanced Prostate Cancer
11 months ago
When is enzalutamide going generic? DAROLUTAMIDE?
A generic version of XTANDI was approved as
enzalutamide
by APOTEX on April 22nd, 2022. Nubeqa aka Darolutamide will be eligible for patent challenges on July 30, 2023. This date may extended up to six months if a pediatric exclusivity extension is applied to the drug's patents.
A generic version of XTANDI was approved as
enzalutamide
by APOTEX on April 22nd, 2022. Nubeqa aka Darolutamide will be eligible for patent challenges on July 30, 2023. This date may extended up to six months if a pediatric exclusivity extension is applied to the drug's patents.
Scout4answers
in
Advanced Prostate Cancer
2 years ago
1
...
9
10
11
...
40
Next page
10
20
30
40
Filter results
Clear filters
Posted in
All communities
Advanced Prostate Cancer
719 results
Fight Prostate Cancer
51 results
Prostate Cancer Network
7 results
View top 10 communities
Sort by
Most Relevant
Newest