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Lu-177 as SOC vs Clinical Trial
Many thanks to all contributors! Since I've now just had my 16th cabazitazel/carboplatin chemo treatment, we're looking at options and working on Lu-177. I'm curious that, since Lu-177 is now FDA approved and is Standard Of Care, is there an advantage to seeking a clinical trial vs receiving it as
Many thanks to all contributors! Since I've now just had my 16th cabazitazel/carboplatin chemo treatment, we're looking at options and working on Lu-177. I'm curious that, since Lu-177 is now FDA approved and is Standard Of Care, is there an advantage to seeking a clinical trial vs receiving it as
MechD
in
Advanced Prostate Cancer
1 year ago
New drug for treating hot flashes under FDA review
This article appeared in Natl Geographic's online daily. Because it is behind a paywall, I have copied it below. While the drug is primarily intended for menopausal women, the article notes that future beneficiaries could include men taking drugs for prostate cancer. Is it possible to cure hot
This article appeared in Natl Geographic's online daily. Because it is behind a paywall, I have copied it below. While the drug is primarily intended for menopausal women, the article notes that future beneficiaries could include men taking drugs for prostate cancer. Is it possible to cure hot
garyjp9
in
Advanced Prostate Cancer
1 year ago
Antipsychotics
my daughter who is 44 has had personality disorder problems since the age of 16. However she has managed a marriage and bringing up two teenage boys . She is now divorced but has a good friendly relationship with her ex. I hate to see some of the meds she seemingly has to take but the latest prescription
my daughter who is 44 has had personality disorder problems since the age of 16. However she has managed a marriage and bringing up two teenage boys . She is now divorced but has a good friendly relationship with her ex. I hate to see some of the meds she seemingly has to take but the latest prescription
m1946
in
Restless Legs Syndrome
2 years ago
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Chemo/Pluvicto or Clinical Trial?
I have stage 4, mcrpc with mets to pelvic lymph nodes and prostate. ADT (Firmagon and Zytiga) kept PSA undetectable for ~2.5 years, then PSA started to rise. I had radiation to prostate in March of this year, which did not help. I started a clinical trial in October at NYU (LAVA 1207 immunotherapy)
I have stage 4, mcrpc with mets to pelvic lymph nodes and prostate. ADT (Firmagon and Zytiga) kept PSA undetectable for ~2.5 years, then PSA started to rise. I had radiation to prostate in March of this year, which did not help. I started a clinical trial in October at NYU (LAVA 1207 immunotherapy)
carguy
in
Advanced Prostate Cancer
1 year ago
Glycine : said to reduce symptoms and reduce aggregation
https://www.michaeljfox.org/grant/modulation-glycine-treatment-parkinsons-disease Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity
https://www.michaeljfox.org/grant/modulation-glycine-treatment-parkinsons-disease Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity
Little_apple
in
Cure Parkinson's
1 year ago
Details of Inhibikase Trial Suspension
Many of us have been following Inhibikase and the recent suspension of trials by the FDA. Inhibikase just issued a press release regarding the concerns expressed by the FDA. "The FDA raised several points, summarized below, in their explanation of the basis for the clinical hold: Further evaluation of
Many of us have been following Inhibikase and the recent suspension of trials by the FDA. Inhibikase just issued a press release regarding the concerns expressed by the FDA. "The FDA raised several points, summarized below, in their explanation of the basis for the clinical hold: Further evaluation of
jimcaster
in
Cure Parkinson's
1 year ago
Crossing an Ocean for Mental Health: Four Athletes Row to Support ADAA
"...What do four female athletes who broke a world record rowing 2,400 nautical miles across the Pacific Ocean and people who suffer from depression, anxiety and co-occurring disorders have in common? At ADAA we pose this seemingly riddle-like question because at first, it was a mystery to us as well
"...What do four female athletes who broke a world record rowing 2,400 nautical miles across the Pacific Ocean and people who suffer from depression, anxiety and co-occurring disorders have in common? At ADAA we pose this seemingly riddle-like question because at first, it was a mystery to us as well
ADAATeamLise
Partner
in
Anxiety and Depression Support
2 years ago
An exciting new clinical trial called STEM-PD is due to start in Sweden and the UK for Parkinson’s.
The symptoms of Parkinson’s are caused by the loss of dopamine-producing nerve cells or neurons in the brain; and researchers have long proposed using cell transplantation as a treatment option for replacing these lost dopamine cells. One challenge presented to research teams however has been generating
The symptoms of Parkinson’s are caused by the loss of dopamine-producing nerve cells or neurons in the brain; and researchers have long proposed using cell transplantation as a treatment option for replacing these lost dopamine cells. One challenge presented to research teams however has been generating
Farooqji
in
Cure Parkinson's
1 year ago
Bionic chip reveals how some antibiotics can harm kidneys
[i]
From left, Amir Livne, Dr. Gil Shamai and Prof. Ron Kimmel, the computer scientists who developed the neural network that examines breast cancer scans. Photo courtesy of the Technion – Israel Institute of Technology
[/i] Breakthrough technology blends sensors and human tissue in a smart kidney
[i]
From left, Amir Livne, Dr. Gil Shamai and Prof. Ron Kimmel, the computer scientists who developed the neural network that examines breast cancer scans. Photo courtesy of the Technion – Israel Institute of Technology
[/i] Breakthrough technology blends sensors and human tissue in a smart kidney
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
1 year ago
Synarel and Lumpy Boobs
Morning everyone! I'm currently on day 9 of downreg, 3rd cycle (1st one was BFN, nothing to freeze and 2nd one was cancelled before stims as my TSH shot up to 10). I'm on Synarel spray this time (was Suprecur previously), and my boobs don't feel like my own. They are super tender which I was expecting
Morning everyone! I'm currently on day 9 of downreg, 3rd cycle (1st one was BFN, nothing to freeze and 2nd one was cancelled before stims as my TSH shot up to 10). I'm on Synarel spray this time (was Suprecur previously), and my boobs don't feel like my own. They are super tender which I was expecting
Camkid12
in
Fertility Network UK
2 years ago
Fretting about using frozen embryo - worried history will repeat
Hi all This time last year I had a FET and carried my baby for 12 weeks before realising there was a problem. It was only at the NHS 12 week scan that we discovered significant issues existed, the tests that followed showed that our baby had Trisomy 18 Edwards Syndrome and we took the decision
Hi all This time last year I had a FET and carried my baby for 12 weeks before realising there was a problem. It was only at the NHS 12 week scan that we discovered significant issues existed, the tests that followed showed that our baby had Trisomy 18 Edwards Syndrome and we took the decision
Skittles11
in
Fertility Network UK
2 years ago
Irisin reduces AS aggregation
Amelioration of pathologic α-synuclein-induced Parkinson’s disease by irisin Irisin is an exercise-induced polypeptide secreted by skeletal muscle that crosses the blood–brain barrier and mediates certain effects of exercise. Here, we show that irisin prevents pathologic α-synuclein (α-syn)-induced
Amelioration of pathologic α-synuclein-induced Parkinson’s disease by irisin Irisin is an exercise-induced polypeptide secreted by skeletal muscle that crosses the blood–brain barrier and mediates certain effects of exercise. Here, we show that irisin prevents pathologic α-synuclein (α-syn)-induced
Little_apple
in
Cure Parkinson's
1 year ago
naltrexone hcl
I was just watching the ads on tv when one for a weight reduction product came up Contrave. I noticed one of the ingredients was naltrexone hcl. This has been mentioned on here before for PD. Interesting. Supposed to stop cravings. “Naltrexone , which blocks opioid receptors, is FDA-approved for
I was just watching the ads on tv when one for a weight reduction product came up Contrave. I noticed one of the ingredients was naltrexone hcl. This has been mentioned on here before for PD. Interesting. Supposed to stop cravings. “Naltrexone , which blocks opioid receptors, is FDA-approved for
LAJ12345
in
Cure Parkinson's
2 years ago
Pluvicto increases radiographic progression-free survival (rPFS) before chemo
This is the early topline results from the
PSMAfore
trial. https://clinicaltrials.gov/ct2/show/NCT04689828 It tested whether giving Pluvicto increases radiographic progression-free survival (rPFS) in men who: (1) have failed one of the second-line hormonals (abiraterone, enzalutamide, darolutamide
This is the early topline results from the
PSMAfore
trial. https://clinicaltrials.gov/ct2/show/NCT04689828 It tested whether giving Pluvicto increases radiographic progression-free survival (rPFS) in men who: (1) have failed one of the second-line hormonals (abiraterone, enzalutamide, darolutamide
Tall_Allen
in
Advanced Prostate Cancer
1 year ago
On goin results on bomedemstat (LSD1 Inhibitor)
Hi All, I have been part of this great group for the last year or so, and although I wish none of us were here, I’m glad to have found an online community that shares the same concerns as myself. I’m 37 years old now and I was diagnosed with ET in 2009 when I was 24, so it was kind of a shock, but
Hi All, I have been part of this great group for the last year or so, and although I wish none of us were here, I’m glad to have found an online community that shares the same concerns as myself. I’m 37 years old now and I was diagnosed with ET in 2009 when I was 24, so it was kind of a shock, but
jafar09
in
MPN Voice
1 year ago
Naringenin (NAR), a natural flavonoid, exhibits neuroprotection against PD-related pathology.
https://www.sciencedirect.com/science/article/abs/pii/S0028390821003865 Naringenin: A prospective therapeutic agent for Alzheimer's and Parkinson's disease https://onlinelibrary.wiley.com/doi/abs/10.1111/jfbc.14415 of substantial evidence for naringenin's neuroprotective efficacy in several experimental
https://www.sciencedirect.com/science/article/abs/pii/S0028390821003865 Naringenin: A prospective therapeutic agent for Alzheimer's and Parkinson's disease https://onlinelibrary.wiley.com/doi/abs/10.1111/jfbc.14415 of substantial evidence for naringenin's neuroprotective efficacy in several experimental
Little_apple
in
Cure Parkinson's
1 year ago
Broccoli Sprout Beverage can clear Acrolein
I am doing a deep dive on the benefits of Broccoli Sprouts and/or Sulforaphane. There seem to be a lot of benefits, so I am posting on them one benefit at a time. As I post more information, I will add the new information to a master document on Broccoli Sprouts - Sulforaphane so we end up with a cohesive
I am doing a deep dive on the benefits of Broccoli Sprouts and/or Sulforaphane. There seem to be a lot of benefits, so I am posting on them one benefit at a time. As I post more information, I will add the new information to a master document on Broccoli Sprouts - Sulforaphane so we end up with a cohesive
Bolt_Upright
in
Cure Parkinson's
1 year ago
just need help
how to cope up with anxiety and depression lasting already over 7 months.
how to cope up with anxiety and depression lasting already over 7 months.
fodd
in
Anxiety and Depression Support
2 years ago
Chronic lymphocytic leukemia treatment algorithm 2022
This 29 November 2022 review article published in the [i]Blood Cancer Journal[/i] presents an up-to-date treatment algorithm for CLL. https://www.nature.com/articles/s41408-022-00756-9 [i]"The treatment landscape for patients with chronic lymphocytic leukemia (CLL) has changed considerably with the
This 29 November 2022 review article published in the [i]Blood Cancer Journal[/i] presents an up-to-date treatment algorithm for CLL. https://www.nature.com/articles/s41408-022-00756-9 [i]"The treatment landscape for patients with chronic lymphocytic leukemia (CLL) has changed considerably with the
CLLerinOz
Administrator
in
CLL Support
2 years ago
OVM-200 Phase 1 clinical trial ( vaccine)
I thought I would start a new thread as the original was about the decision making but now I’m in it I realise a clean thread may help. So today is day 15 of the trial and I am getting the second dose of the vaccine ( subject to clearing the screening this morning). I will then be observed for 4 hours
I thought I would start a new thread as the original was about the decision making but now I’m in it I realise a clean thread may help. So today is day 15 of the trial and I am getting the second dose of the vaccine ( subject to clearing the screening this morning). I will then be observed for 4 hours
Brysonal
in
Fight Prostate Cancer
2 years ago
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