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Proteus
Good morning Did anyone participate in the proteus clinical trial. Thanks
Good morning Did anyone participate in the proteus clinical trial. Thanks
Johnko
in
Advanced Prostate Cancer
2 years ago
What is AMX0035, and Why Is It Important for All of Us?
AMX0035 is a drug combination of sodium phenylbutyrate (PB) and tauroursodeoxycholic acid (TUDCA). It works by regulating the mitochondrial (cell power supply) and endoplasmic reticulum (quality control centers). Put simply, both processes should work in unison, but when they don’t, cells in the body
AMX0035 is a drug combination of sodium phenylbutyrate (PB) and tauroursodeoxycholic acid (TUDCA). It works by regulating the mitochondrial (cell power supply) and endoplasmic reticulum (quality control centers). Put simply, both processes should work in unison, but when they don’t, cells in the body
SilentEchoes
in
Cure Parkinson's
2 years ago
Ferroptosis is a hot topic for Parkinsons research in 2022
New opinion piece reviews the association between iron deposition, glial activation, & neuronal death, explores how ferroptosis affects α-synuclein aggregation, & reviews clinical trials https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(22)00044-2 https://twitter.com/ScienceofPD/status
New opinion piece reviews the association between iron deposition, glial activation, & neuronal death, explores how ferroptosis affects α-synuclein aggregation, & reviews clinical trials https://www.cell.com/trends/molecular-medicine/fulltext/S1471-4914(22)00044-2 https://twitter.com/ScienceofPD/status
Hidden
in
Cure Parkinson's
2 years ago
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Social anxiety, selective mutism
Today, I again felt like, I am not able to speak up for myself or for my rights. I am so sensitive. I take people criticism personally. I feel afraid from people. I feel like there is no cure for my social anxiety. I feel so terrible. I feel like giving up. I don't know what to do. I am in depression
Today, I again felt like, I am not able to speak up for myself or for my rights. I am so sensitive. I take people criticism personally. I feel afraid from people. I feel like there is no cure for my social anxiety. I feel so terrible. I feel like giving up. I don't know what to do. I am in depression
Shashwat2331
in
Anxiety and Depression Support
2 years ago
mental state
i’m just wondering how everyones mental state has been ever since they first showed signs of AF or WPW and how its been since your ablation… my depression and anxiety has decreased quite a bit over the past few months but there are still days where it is tough. at times i feel like im going to panic
i’m just wondering how everyones mental state has been ever since they first showed signs of AF or WPW and how its been since your ablation… my depression and anxiety has decreased quite a bit over the past few months but there are still days where it is tough. at times i feel like im going to panic
september1990
in
Arrhythmia Alliance
2 years ago
mental state
i’m just wondering how everyones mental state has been ever since they first showed signs of AF or WPW and how its been since your ablation… my depression and anxiety has decreased quite a bit over the past few months but there are still days where it is tough. at times i feel like im going to panic
i’m just wondering how everyones mental state has been ever since they first showed signs of AF or WPW and how its been since your ablation… my depression and anxiety has decreased quite a bit over the past few months but there are still days where it is tough. at times i feel like im going to panic
september1990
in
AF Association
2 years ago
MABs - Encouraging, but not really
Couple things…. 1. Has anyone taking Calquence received a MAB infusion? Waiting to hear from my Dr to confirm it’s safe and doesn’t cause any drug interactions. Seems unlikely, but I want to be certain. 2. Applied for a MAB infusion via the Stanford Health process and explained that, although I didn
Couple things…. 1. Has anyone taking Calquence received a MAB infusion? Waiting to hear from my Dr to confirm it’s safe and doesn’t cause any drug interactions. Seems unlikely, but I want to be certain. 2. Applied for a MAB infusion via the Stanford Health process and explained that, although I didn
OaktownN
in
CLL Support
2 years ago
Encouraging results from the phase-I trial! The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in PD
Highlights
• Oral NR increases brain NAD levels in individuals with Parkinson’s disease • NR intake alters cerebral metabolism in Parkinson’s disease • Cerebral NAD increase is associated with clinical improvement in Parkinson’s disease • NR induces transcription of mitochondrial, lysosomal, and
Highlights
• Oral NR increases brain NAD levels in individuals with Parkinson’s disease • NR intake alters cerebral metabolism in Parkinson’s disease • Cerebral NAD increase is associated with clinical improvement in Parkinson’s disease • NR induces transcription of mitochondrial, lysosomal, and
Hidden
in
Cure Parkinson's
2 years ago
Reduced risk of Alzheimers disease in 15,820 people with T2D randomized to GLP-1R agonists in clinical trials and in Danish registry
Reduced risk of incident #Alzheimers disease in 15,820 people with #T2D randomized to GLP-1R agonists in clinical trials and in Danish registry data https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/trc2.12268
Reduced risk of incident #Alzheimers disease in 15,820 people with #T2D randomized to GLP-1R agonists in clinical trials and in Danish registry data https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/trc2.12268
Hidden
in
Cure Parkinson's
2 years ago
Anyone have experience with Molnupiravir?
I was diagnosed with CLL in 2013. Commenced Acalabrutinib in a clinical trial August 2020. Progress going reasonably well. I am triple vaccinated against covid19. Immunity if any is questionable? Molnupiravir, an antiviral medication was recently added to our PBS for access by high risk (blood cancer
I was diagnosed with CLL in 2013. Commenced Acalabrutinib in a clinical trial August 2020. Progress going reasonably well. I am triple vaccinated against covid19. Immunity if any is questionable? Molnupiravir, an antiviral medication was recently added to our PBS for access by high risk (blood cancer
spanish36
in
CLL Support
2 years ago
Another useful article showing minimal adverse effect dosing with T3 in addition to T4
This downloadable paper has studied the effects of T3 administration on women with some residual thyroid working. T3 in combination gave better health signs when T4 only was given in therapy. T3 only therapy is still a step medicine won't yet tread, but at least combination therapy is now seriously
This downloadable paper has studied the effects of T3 administration on women with some residual thyroid working. T3 in combination gave better health signs when T4 only was given in therapy. T3 only therapy is still a step medicine won't yet tread, but at least combination therapy is now seriously
diogenes
in
Thyroid UK
2 years ago
Top 10 Parkinson's Disease Clinical Trials [2022 Studies]
https://www.withpower.com/clinical-trials/parkinson's-disease?utm_campaign=owned&utm_content=tweet&utm_medium=community&utm_source=twitter&utm_term=condition-link-post&code=gjfw&pathParts=clinical-trials%2Cparkinson%27s-disease
https://www.withpower.com/clinical-trials/parkinson's-disease?utm_campaign=owned&utm_content=tweet&utm_medium=community&utm_source=twitter&utm_term=condition-link-post&code=gjfw&pathParts=clinical-trials%2Cparkinson%27s-disease
Farooqji
in
Cure Parkinson's
2 years ago
Should Early Use of Chemotherapy Be Avoided in the Treatment of Metastatic Prostate Cancer?
Interesting editorial in JMA [Japan Medical Association] Journal: "The therapeutic strategy for advanced prostate cancer has dramatically changed recently. Previously, docetaxel was the only drug with evidences showing improved overall survival (OS) in metastatic castration-resistant prostate cancer
Interesting editorial in JMA [Japan Medical Association] Journal: "The therapeutic strategy for advanced prostate cancer has dramatically changed recently. Previously, docetaxel was the only drug with evidences showing improved overall survival (OS) in metastatic castration-resistant prostate cancer
pjoshea13
in
Advanced Prostate Cancer
2 years ago
I am seeking stem cell treatment for my PD. Both accredited institutions and clinical trial groups are acceptable. Find me adresses
adulte Stammzellen
adulte Stammzellen
Will19parkiscore
in
Cure Parkinson's
2 years ago
The Science of Parkinson's: The mannitol clinical trial results
Not sure if anyone posted this before as it is from Feb 4th. Dr. Simons mentions our HU community. https://scienceofparkinsons.com/2022/02/04/mannitol-2/
Not sure if anyone posted this before as it is from Feb 4th. Dr. Simons mentions our HU community. https://scienceofparkinsons.com/2022/02/04/mannitol-2/
Hidden
in
Cure Parkinson's
2 years ago
Clinical Trials - how often do they allow crossovers?
Clinical Trial Crossovers. Do you know if in blind trials, if the people getting the new drug get better results how often do they then allow the people that were getting the placebo to start getting the new drug? Thanks.
Clinical Trial Crossovers. Do you know if in blind trials, if the people getting the new drug get better results how often do they then allow the people that were getting the placebo to start getting the new drug? Thanks.
davebliz
in
Advanced Prostate Cancer
2 years ago
Efficacy of Ginger Supplementation in Relieving Persistent Hypothyroid Symptoms in Patients with Controlled Primary Hypothyroidism
From the unlikely-to-do-any-harm school of medicine - and good if it helps. :-)
[i]
Efficacy of Ginger Supplementation in Relieving Persistent Hypothyroid Symptoms in Patients with Controlled Primary Hypothyroidism: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Abstract
From the unlikely-to-do-any-harm school of medicine - and good if it helps. :-)
[i]
Efficacy of Ginger Supplementation in Relieving Persistent Hypothyroid Symptoms in Patients with Controlled Primary Hypothyroidism: A Pilot Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Abstract
helvella
Thyroid UK
in
Thyroid UK
2 years ago
Promissing Research
Hello, Hope you can enjoy this promissing news. I found a Phase I/II clinical trial on humans. https://www.vhio.net/myc-inhibition-halts-metastatic-breast-cancer-progression-by-blocking-tumor-growth-invasion-seeding/ Lovexxx Lucie
Hello, Hope you can enjoy this promissing news. I found a Phase I/II clinical trial on humans. https://www.vhio.net/myc-inhibition-halts-metastatic-breast-cancer-progression-by-blocking-tumor-growth-invasion-seeding/ Lovexxx Lucie
Lulu4545
in
SHARE Metastatic Breast Cancer
2 years ago
Dealing with the holidays: Part 1
Tis the season where words like “thankful”, “grateful”, “blessed”, and “gratitude” seem to find their way into virtually every conversation. If these words hold some joy and/or positive associations for you, that’s amazing. However, for many people, these words are (in essence) weaponized. Those who
Tis the season where words like “thankful”, “grateful”, “blessed”, and “gratitude” seem to find their way into virtually every conversation. If these words hold some joy and/or positive associations for you, that’s amazing. However, for many people, these words are (in essence) weaponized. Those who
The_Color_Blue
in
Anxiety and Depression Support
2 years ago
Duke DASH clinical trial update
This one entitled "Goodness" https://whynotsmile.org/2022/02/22/goodness/
This one entitled "Goodness" https://whynotsmile.org/2022/02/22/goodness/
HerbieP
in
Advanced Prostate Cancer
2 years ago
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