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Worrying study on long-term ADT (esp Enza)
I just came across a study (2019 International Journal of Pharmacology) that suggests that long-term use of ADT can cause neuroendicrine differentiation, leading to rapid spread and more aggressive spread. (the article was actually about the use of propanalol to counteract the effect of NED, but the
I just came across a study (2019 International Journal of Pharmacology) that suggests that long-term use of ADT can cause neuroendicrine differentiation, leading to rapid spread and more aggressive spread. (the article was actually about the use of propanalol to counteract the effect of NED, but the
CrocodileShoes
in
Advanced Prostate Cancer
1 year ago
No Longer Undetectable, PSMA-CT Results
I posted a few days ago about the fact that my husband had been undetectable since his prostate was removed in April of 2021. And then on 3/31 his PSA was 6.3 and on 4/03 it was 7.1. The oncologist ordered a PSMA-CT scan and that was done today. The oncologist's PA called us with the results and she
I posted a few days ago about the fact that my husband had been undetectable since his prostate was removed in April of 2021. And then on 3/31 his PSA was 6.3 and on 4/03 it was 7.1. The oncologist ordered a PSMA-CT scan and that was done today. The oncologist's PA called us with the results and she
DesertDaisy
in
Fight Prostate Cancer
1 year ago
No Longer Undetectable, PSMA Results
I posted a few days ago about the fact that my husband had been undetectable since his prostate was removed in April of 2021. And then on 3/31 his PSA was 6.3 and on 4/03 it was 7.1. The oncologist ordered a PSMA-CT scan and that was done today. The oncologist's PA called us with the results and she
I posted a few days ago about the fact that my husband had been undetectable since his prostate was removed in April of 2021. And then on 3/31 his PSA was 6.3 and on 4/03 it was 7.1. The oncologist ordered a PSMA-CT scan and that was done today. The oncologist's PA called us with the results and she
DesertDaisy
in
Advanced Prostate Cancer
1 year ago
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Not Tolerating Xtandi
I started Xtandi 11/30/22 on top of Orgovix when PSA was 29 . Late January23 PSA was down to 4.1 and i was tolerating it well i thought. I dont want to let the beast loose but dont want to kill myself either. Recently 4/7/23 had an issue with my neck and shoulder causing so much pain I could not turn
I started Xtandi 11/30/22 on top of Orgovix when PSA was 29 . Late January23 PSA was down to 4.1 and i was tolerating it well i thought. I dont want to let the beast loose but dont want to kill myself either. Recently 4/7/23 had an issue with my neck and shoulder causing so much pain I could not turn
rick8637
in
Advanced Prostate Cancer
1 year ago
PSA on ADT but post EBRT
Hi everyone! Just wondering if anyone has any info to share regarding psa after radiation but while still on adt. My dad who is stage T3b started Eligard in August 2022 (2 year course) followed by high dose brachytherapy in December and 23 sessions EBRT Dec-Jan 2023. His psa in Oct 2022 (pre-radiation
Hi everyone! Just wondering if anyone has any info to share regarding psa after radiation but while still on adt. My dad who is stage T3b started Eligard in August 2022 (2 year course) followed by high dose brachytherapy in December and 23 sessions EBRT Dec-Jan 2023. His psa in Oct 2022 (pre-radiation
ChloeSS
in
Advanced Prostate Cancer
1 year ago
Recurrance with pelvic lymph nodes back on Zoladex
Hi its been a while since l wrote but always viewing and supporting.Question my husband has a recurrence of his cancer he had a scan which showed pelvic lymph nodes involved. Back on Zoladex 3 montly injections first psa dropped from 57 to 3.1, second injection administered, just had psa results and
Hi its been a while since l wrote but always viewing and supporting.Question my husband has a recurrence of his cancer he had a scan which showed pelvic lymph nodes involved. Back on Zoladex 3 montly injections first psa dropped from 57 to 3.1, second injection administered, just had psa results and
Knittingque
in
Advanced Prostate Cancer
1 year ago
PSA up today
Hi, I’ve been in the triple therapy since March 2022 and things are going well. Had a blood test today and everything looks good except PSA went from 0.01 to 0.03, bilirubin at 20 and ALT at 5.0. I go for my next lupron should next Tuesday. Is there anything I should be concerned about and what questions
Hi, I’ve been in the triple therapy since March 2022 and things are going well. Had a blood test today and everything looks good except PSA went from 0.01 to 0.03, bilirubin at 20 and ALT at 5.0. I go for my next lupron should next Tuesday. Is there anything I should be concerned about and what questions
Lslal
in
Advanced Prostate Cancer
1 year ago
My First official medal. Monsal 10k
On 3rd of October last year, Floss asked me if I would like to run the Monsal Trail event with her in April. The 10k🤔? I asked, or maybe the HM? said Floss... Definately the 10k for me, I laughed, and we entered.Shortly after this, around Mr BBr's 67th birthday, we were reeling. Having suspicions that
On 3rd of October last year, Floss asked me if I would like to run the Monsal Trail event with her in April. The 10k🤔? I asked, or maybe the HM? said Floss... Definately the 10k for me, I laughed, and we entered.Shortly after this, around Mr BBr's 67th birthday, we were reeling. Having suspicions that
Bluebirdrunner
Graduate10
in
Bridge to 10K
1 year ago
Side effects
I do 5 mg of prednisone 1000 mg of abiraterone and Lupron every 4 months. Prednisone has been very tough on me, I've gained 29 pounds weight in two months, the muscle cramps and feet twitching are unbearable. My PSA has come down from 24 in January to 0.84 last Monday. I saw my oncologist on Tuesday
I do 5 mg of prednisone 1000 mg of abiraterone and Lupron every 4 months. Prednisone has been very tough on me, I've gained 29 pounds weight in two months, the muscle cramps and feet twitching are unbearable. My PSA has come down from 24 in January to 0.84 last Monday. I saw my oncologist on Tuesday
Blueribbon63
in
Advanced Prostate Cancer
1 year ago
Recently diagnosed- Stage 4 at 45 yrs old.
Hey all! I’m an active 45 year old Australian, dad of 10 and 12 year old, living in Vermont USA, and I just recently got diagnosed with stage 4 prostate cancer. Mets to lymph nodes, several vertebrea, hip, rib etc. Gleason 9 and a relatively low PSA at 6.7 which is unusual. Apparently the sign
Hey all! I’m an active 45 year old Australian, dad of 10 and 12 year old, living in Vermont USA, and I just recently got diagnosed with stage 4 prostate cancer. Mets to lymph nodes, several vertebrea, hip, rib etc. Gleason 9 and a relatively low PSA at 6.7 which is unusual. Apparently the sign
dochelem
in
Advanced Prostate Cancer
1 year ago
ART Radiation dose and ADT in localized PCa: a meta-regression of 5-year outcomes in phase III random control trials; 21,429 patients
I have had 21 months of ADT and also have decided to stop short of my suggested 24 months total treatment as of December, 2022; I cant take the low TET anymore and its consequent impacts. Just when I was doubting my choice to move to long term ADT (LTADT) after salvage radiation (sRT) I stumbled on this
I have had 21 months of ADT and also have decided to stop short of my suggested 24 months total treatment as of December, 2022; I cant take the low TET anymore and its consequent impacts. Just when I was doubting my choice to move to long term ADT (LTADT) after salvage radiation (sRT) I stumbled on this
RMontana
in
Active Surveillance - Prostate Cancer
1 year ago
TURP Prior to Radiation: Opinions?
63yo, Gleason 4+4, PSA 0.055, 2 measurable mets in pelvic lymph nodes-right iliac chain I finished a round of 6 chemo treatments in mid-February. I'm currently on Lupron and Nubeqa. My last PSA was 0.055. I decided to take a break before I start radiation in August or September to do some travel and
63yo, Gleason 4+4, PSA 0.055, 2 measurable mets in pelvic lymph nodes-right iliac chain I finished a round of 6 chemo treatments in mid-February. I'm currently on Lupron and Nubeqa. My last PSA was 0.055. I decided to take a break before I start radiation in August or September to do some travel and
Peeffervescence
in
Advanced Prostate Cancer
1 year ago
when do you take a break
Just wondering i do 5 mg of prednisone 1000 mg of abiraterone and Lupron every 3months plus bone so I've been on this now 10 months PSA is less than 0.001, so at what point do you take a break looking into the future how do you know when to take that break and what if the cancer comes back do you start
Just wondering i do 5 mg of prednisone 1000 mg of abiraterone and Lupron every 3months plus bone so I've been on this now 10 months PSA is less than 0.001, so at what point do you take a break looking into the future how do you know when to take that break and what if the cancer comes back do you start
jptss
in
Advanced Prostate Cancer
1 year ago
prostate cancer
started treatment at John Hopkins in 2008 with Dr Walsh (best in world) Gleason 9.9 with prostate removed. Continue at UAB and cancer center (Georgia) with great treatment’s radiation and chemotherapy through 2021 when all doctors and teams retired or moved to other locations. Used Lynparza and Xtandi
started treatment at John Hopkins in 2008 with Dr Walsh (best in world) Gleason 9.9 with prostate removed. Continue at UAB and cancer center (Georgia) with great treatment’s radiation and chemotherapy through 2021 when all doctors and teams retired or moved to other locations. Used Lynparza and Xtandi
Oren1
in
Advanced Prostate Cancer
1 year ago
Eligard failure?
Bear with me as I list the details behind my questions. I am currently receiving radiation treatment at UCLA under Dr Kishan on the Viewray (20 treatments vs 5 due to Prostox DNA test showing high risk to long term SE's from higher dose of radiation) and only have 2 treatments to go. Prior to coming
Bear with me as I list the details behind my questions. I am currently receiving radiation treatment at UCLA under Dr Kishan on the Viewray (20 treatments vs 5 due to Prostox DNA test showing high risk to long term SE's from higher dose of radiation) and only have 2 treatments to go. Prior to coming
LongevityAT
in
Advanced Prostate Cancer
1 year ago
Abiraterone plus Prednisone and 3 monthly injection failing now in 79 year old dad with mets to bone on NHS in UK.
Hi Everyone, This site has been a great comfort and source of knowledge for me. I'm travelling down a difficult road. I've had a brain tumour/brain surgery. My mother has severe dementia. My father was diagnosed with PC in 2018. He had prostate removed in 2019, but cancer had already spread outside prostate
Hi Everyone, This site has been a great comfort and source of knowledge for me. I'm travelling down a difficult road. I've had a brain tumour/brain surgery. My mother has severe dementia. My father was diagnosed with PC in 2018. He had prostate removed in 2019, but cancer had already spread outside prostate
Lemonpower
in
Advanced Prostate Cancer
1 year ago
New To The Thread
63yo, 4+4=8 Gleason, PSA 0.05 (56 before treatment). I’m doing the triplet treatments with Lupron, Nubeqa, and taxotere (for chemo). My med oncologist has called it the STAMPEDE trial, although I’m not actually in a trial. I was diagnosed last August and recently finished chemo. I’m still on ADT.
63yo, 4+4=8 Gleason, PSA 0.05 (56 before treatment). I’m doing the triplet treatments with Lupron, Nubeqa, and taxotere (for chemo). My med oncologist has called it the STAMPEDE trial, although I’m not actually in a trial. I was diagnosed last August and recently finished chemo. I’m still on ADT.
Peeffervescence
in
Advanced Prostate Cancer
1 year ago
Adenocarcinoma / Ductal Carcinoma PC
We just found out my 86 yr old father's "bladder cancer" biopsy is actually ductal carcinoma. The tumor was on the urethra, and has been bleeding since August 2022. His PSA was 4.2, which was the same psa I had when I was diagnosed. However, I have adenocarcinoma. With the knowledge of his cancer
We just found out my 86 yr old father's "bladder cancer" biopsy is actually ductal carcinoma. The tumor was on the urethra, and has been bleeding since August 2022. His PSA was 4.2, which was the same psa I had when I was diagnosed. However, I have adenocarcinoma. With the knowledge of his cancer
280scout
in
Advanced Prostate Cancer
1 year ago
No Longer Undetectable
Hello Everyone, I just posted this on APC, but want to post it on FPC also as I know some of you are not on APC any longer and I am looking for advice. My husband had his prostate removed in April 2021. The cancer had spread out of the capsule and one lymph node was positive. His cancer is both acinar
Hello Everyone, I just posted this on APC, but want to post it on FPC also as I know some of you are not on APC any longer and I am looking for advice. My husband had his prostate removed in April 2021. The cancer had spread out of the capsule and one lymph node was positive. His cancer is both acinar
DesertDaisy
in
Fight Prostate Cancer
1 year ago
No Longer Undetectable
My husband had his prostate removed in April 2021. The cancer had spread out of the capsule and one lymph node was positive. His cancer is both acinar and ductal. After surgery he was given a 6 month Lupron shot and that is the only treatment he has had since. Details are in my profile. He is
My husband had his prostate removed in April 2021. The cancer had spread out of the capsule and one lymph node was positive. His cancer is both acinar and ductal. After surgery he was given a 6 month Lupron shot and that is the only treatment he has had since. Details are in my profile. He is
DesertDaisy
in
Advanced Prostate Cancer
1 year ago
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