Why would my Alk Phos go up after just starting urso?

[Toddyboo]

Hi All,

I have a question and wondered if anyone had an answer to if they had a similar experience.

I just started taking Urso and have been on it now close to a month my recent blood work shows that my Alk Phos has increased rather than decreased. While I know it may take awhile for Urso to potentially decrease ones Alk Phos levels, why would my Alk Phos all of the suddent be higher than its been (compared to my bloodwork over the past year)??

[Samanthaann]

my doctor told me it can take a year to see results and that it could fluctuate.

[DonnaBoll Administrator]

I know all too well how disheartening it is to have your numbers increase. The best advice I can give you is be patient. Lab work, according to the Standard of Care, should be drawn every 3-6 months. What are your numbers? It's really important, after some time being on the Urso has passed, to always look at the overall trend of your numbers. The results of any alk phos is the amount of alk phos in your blood at exactly that moment when the blood was drawn - that's why you really need to look at the trend over time. It can often take up to a year to see if you are a responder to Urso or not. You mentioned you've had labs drawn - but only on Urso for a month. Be sure you are on the right dose - this is so crucial for the best results. It is ALWAYS based only on your body weight - never symptoms or lab results. Dosage is 13-15mgs/kg. I hope some of this helps. I know how scary this disease can be.