Assuming same range as previous post for Ft4 (9-19)
FT4: 10 pmol/l (Range 9 - 19)
Ft4 is only a dismal 10.00% through range
Most people on just levothyroxine will need Ft4 at least 60-70% through range
Insist on 25mcg dose increase in levothyroxine and retest in 6-8 weeks
Likely to need several further increases in levothyroxine over coming months
Standard STARTER dose levothyroxine is 50mcg unless over 65 years old
Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test
This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)
Is this how you did test
Important to also test vitamin D, folate, B12 and ferritin
Exactly What vitamin supplements are you currently taking
You need to retest vitamin D twice year when supplementing
And retest folate and B12 at least annually
If on iron supplements GP should do full iron panel at least 3 times a year minimum
Levothyroxine doesn’t top up failing thyroid it replaces it.
Unless extremely petite you’re likely to eventually be on at least 100mcg levothyroxine per day
Even if we frequently start on only 50mcg, most people need to increase levothyroxine dose slowly upwards in 25mcg steps (retesting 6-8 weeks after each increase) until eventually on, or near full replacement dose
Consider starting levothyroxine at a dosage of 1.6 micrograms per kilogram of body weight per day (rounded to the nearest 25 micrograms) for adults under 65 with primary hypothyroidism and no history of cardiovascular disease.
In the majority of patients 50-100 μg thyroxine can be used as the starting dose. Alterations in dose are achieved by using 25-50 μg increments and adequacy of the new dose can be confirmed by repeat measurement of TSH after 2-3 months.
The majority of patients will be clinically euthyroid with a ‘normal’ TSH and having thyroxine replacement in the range 75-150 μg/day (1.6ug/Kg on average).
The recommended approach is to titrate thyroxine therapy against the TSH concentration whilst assessing clinical well-being. The target is a serum TSH within the reference range.
……The primary target of thyroxine replacement therapy is to make the patient feel well and to achieve a serum TSH that is within the reference range. The corresponding FT4 will be within or slightly above its reference range.
The minimum period to achieve stable concentrations after a change in dose of thyroxine is two months and thyroid function tests should not normally be requested before this period has elapsed.
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