NAD+ has anyone tried this supplement?

[Wrayofsunshine]

Hi all,

Just had a friend visiting from the States who has battled severe fatigue since having covid, he doesn't have a thyroid condition. He found a supplement called NAD+ really helped him with fatigue. I can't find any info online in relation to this supplement and underactive thyroid, but wondered if anyone had used it?

Brief history, I was diagnosed Jan 23 and am now on 75mg Levo but still feeling rubbish, very tired, muscle aches, hair falling out. Currently waiting for latest blood test results from GP (had bloods taken yesterday). Am supplementing with Vit Bs, Zinc, Selenium etc and am gluten and dariy free. Keen to try anything that might help but also don't want to waste money if others have tried this NAD+ and it really doesn't work.

Thank you!

[bookish]

Hi, I've no experience with NAD+ but knew it was mentioned in discussions of folate cycle and methyl group use. Covid can deplete B vitamins and methyl groups ncbi.nlm.nih.gov/pmc/articl...

Metabolism of NAD+ will use up methyl groups, so may be of use, but only if you have enough methyl to allow it to metabolise fully but without compromising other methyl group functions, if I understand this correctly, so he may find that over time other issues occur if not enough availability. Likelihood is as he'd found NAD+ that he also knows this and is supplementing. emersonecologics.com/blog/p....

Which Bs are you taking and in what form and did you test first?

Cheers

[Cilla_]

I have only just started taking it after reading this articlencbi.nlm.nih.gov/pmc/articl...

I also take ubiquinol (reduced form of coq10), taurine, and and vitamin c for the adrenals (although I need to cut back drastically as my blood got really thin lately after taking 2500mg daily for a few months). I have also purchased sunflower lecithin. I take basically every vitamin and mineral around as I also have issue with pancreatic insufficiency, and all B-vitamins are methylated that I take. I am on half a grain twice daily of NDT and 50 mg Levothyroxine and a betablocker for another condition. Taurine really does seem to work for me which I am happy about and ubiquinol is the reason I can get out of bed every morning. I have some kind of mitochondrial dysfunction after a virus in 2004. Was dx ME/CFS in 2014 but we now know I also have a number of autoimmune diseases and had low t3 syndrome! I guess I am waiting for the authorities to admit ME/CFS is actually an mitochondrial dysfunction. Was finally dx hypothyroid in pregnancy, shortly after the low t3 diagnosis. Both autoimmune and salicylate poisoning (!)lies in the background there.

[Stourie]

why are you still only on 75 mcg of levo since March? You are supposed to have a blood test 6 - 8 weeks after a raise. You are still on a really low dose. What are your blood results. Jo xx