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Xtandi
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I wonder if I am the only cancer guy with this exhaustion
I know many of you say you are tired....I now started on
Xtandi
..just 1 to start , but once again (I sound like a recording..saying this over and over...but I know this exhaustion is not normal...ever since my Provenge trtmt.
I know many of you say you are tired....I now started on
Xtandi
..just 1 to start , but once again (I sound like a recording..saying this over and over...but I know this exhaustion is not normal...ever since my Provenge trtmt.
sidnw
in
Advanced Prostate Cancer
6 years ago
Don’t know where I go from here.
I have been through: Lupron continuous from beginning, Strive, Docetaxal,
Xtandi
, Radium 223, Cabazitaxel, Mitoxantrone and other radiation treatments for pain etc. You can go back and look at my prior post for better timeline.
I have been through: Lupron continuous from beginning, Strive, Docetaxal,
Xtandi
, Radium 223, Cabazitaxel, Mitoxantrone and other radiation treatments for pain etc. You can go back and look at my prior post for better timeline.
Glsn10
in
Advanced Prostate Cancer
6 years ago
Radium 223 (Xofigo)
So I’ve been taking
Xtandi
and having a very difficult time. Today my oncologist said to stop it as she could see how it was affecting me. Starting me on Radrum 223 (Xofigo). Don’t see anything on this here when I do a search......any words of wisdom?
So I’ve been taking
Xtandi
and having a very difficult time. Today my oncologist said to stop it as she could see how it was affecting me. Starting me on Radrum 223 (Xofigo). Don’t see anything on this here when I do a search......any words of wisdom?
Jashelby
in
Advanced Prostate Cancer
6 years ago
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Castration resistant prostate cancer
Thus far, I have had 39 radiation treatments, have been on Lupron for over one year (in tandem with Bicumulide first, and now
Xtandi
). Due to a recent increase in my PSA, I will soon begin Provenge treatment.
Thus far, I have had 39 radiation treatments, have been on Lupron for over one year (in tandem with Bicumulide first, and now
Xtandi
). Due to a recent increase in my PSA, I will soon begin Provenge treatment.
N-Kitch
in
Advanced Prostate Cancer
6 years ago
Olaparib/Durvalumab Combo Shows Promise in mCRPC
“But emerging data suggest potential activity in combinations, as seen with results reported with enzalutamide (
Xtandi
) plus pembrolizumab (Keytruda) and with a DNA-based vaccine plus pembrolizumab.”
“But emerging data suggest potential activity in combinations, as seen with results reported with enzalutamide (
Xtandi
) plus pembrolizumab (Keytruda) and with a DNA-based vaccine plus pembrolizumab.”
JLS1
in
Advanced Prostate Cancer
6 years ago
Xtandi and Increasing PSA
My father has Been on
Xtandi
, since September 20 2017. (3.5mo) his PSA is going up and his last reading was today 14. Sept 4.1, 6.44 and now 14!! I guess it’s not working and his cancer is not responding to it. Anyone else have this happen? What did your oncologist do?
My father has Been on
Xtandi
, since September 20 2017. (3.5mo) his PSA is going up and his last reading was today 14. Sept 4.1, 6.44 and now 14!! I guess it’s not working and his cancer is not responding to it. Anyone else have this happen? What did your oncologist do?
Daddysdaughter
in
Advanced Prostate Cancer
6 years ago
thoughts from a newby
First line hormone therapy (ADT) injection degarelix Firmagon, another ADT docetaxel Taxotere, chemotherapy now given alongside ADT abiraterone Zytiga enzalutamide Extandi,
Xtandi
Prednisone or Prednisolone, corticosteroid (type of steroid) to treat/avoid allergies Ra 223 dichoride Xofigo
First line hormone therapy (ADT) injection degarelix Firmagon, another ADT docetaxel Taxotere, chemotherapy now given alongside ADT abiraterone Zytiga enzalutamide Extandi,
Xtandi
Prednisone or Prednisolone, corticosteroid (type of steroid) to treat/avoid allergies Ra 223 dichoride Xofigo
rpol
in
Advanced Prostate Cancer
6 years ago
Anyone with similar experience?
Then treated with taxotere with prednisone and xgeva injections then treated with cabazitaxel and finally
xtandi
while still getting xgeva injections monthly. The
xtandi
seemed to be working well - brought his PSA down to .80 but suddenly he had difficulty walking.
Then treated with taxotere with prednisone and xgeva injections then treated with cabazitaxel and finally
xtandi
while still getting xgeva injections monthly. The
xtandi
seemed to be working well - brought his PSA down to .80 but suddenly he had difficulty walking.
GTWaites
in
Advanced Prostate Cancer
6 years ago
Going wrong way after only 6 months
Now trying to get insurance to allow addition of
xtandi
to my mix. Hoping for the best...I have grand kids who need to learn a lot from me. Doug
Now trying to get insurance to allow addition of
xtandi
to my mix. Hoping for the best...I have grand kids who need to learn a lot from me. Doug
Shooter1
in
Advanced Prostate Cancer
6 years ago
Ten year battle is over.
After 10 years of ADT, brachytherapy, IMRT, HDK,
Xtandi
, Zytiga, Xofigo, etc., my husband, Bob, passed away on Monday evening, November 6. He was able to go to Duke in late August and was approved for Keytruda under Merck's open access program.
After 10 years of ADT, brachytherapy, IMRT, HDK,
Xtandi
, Zytiga, Xofigo, etc., my husband, Bob, passed away on Monday evening, November 6. He was able to go to Duke in late August and was approved for Keytruda under Merck's open access program.
23casa
in
Advanced Prostate Cancer
6 years ago
Xtandi and alcohol
Can’t find anything in the literature to say if this has an influence on the efficacy of
xtandi
. Doctor doesn’t seem to think so but I was wondering if anybody has views on this
Can’t find anything in the literature to say if this has an influence on the efficacy of
xtandi
. Doctor doesn’t seem to think so but I was wondering if anybody has views on this
Hidden
in
Advanced Prostate Cancer
6 years ago
Jevtana [Cabazitaxel] & Androgen Status.
(d) An antiandrogen such as Casodex of
Xtandi
, if not resistant, will inhibit AR activity. (e) Zytiga, if not resistant, will prevent the conversion of pregnenolone and progesterone to androgens.
(d) An antiandrogen such as Casodex of
Xtandi
, if not resistant, will inhibit AR activity. (e) Zytiga, if not resistant, will prevent the conversion of pregnenolone and progesterone to androgens.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Relief of abdominal bloating and gas pain
I am having a lot of abdominal bloating and gas pain since starting
Xtandi
. I have been taking Simethicone 180 mg soft gels, gas relief and prevention enzyme supplement 1 capsule per day, and probiotic colon support 1 capsule per day.
I am having a lot of abdominal bloating and gas pain since starting
Xtandi
. I have been taking Simethicone 180 mg soft gels, gas relief and prevention enzyme supplement 1 capsule per day, and probiotic colon support 1 capsule per day.
chascri
in
Advanced Prostate Cancer
6 years ago
Xtandi and Tumeric
My father is on
Xtandi
and he was told to stop taking tumeric because it decreases the effectiveness for the
Xtandi
.. he also was told to stop green tea. We recently decreased his
Xtandi
dose to 3 pills instead of 4 because he was having unusual chest pain and depression from the full dose.
My father is on
Xtandi
and he was told to stop taking tumeric because it decreases the effectiveness for the
Xtandi
.. he also was told to stop green tea. We recently decreased his
Xtandi
dose to 3 pills instead of 4 because he was having unusual chest pain and depression from the full dose.
Daddysdaughter
in
Advanced Prostate Cancer
7 years ago
Back to Chemo
His PSAs have doubled every month for the last three months and his onc wanted to put him on
Xtandi
but we were unable to afford the co-pay of $3,000 (which is the negotiated price we were able to get the drug down to each month) so doc put him on ketoconazole and prednisone in October.
His PSAs have doubled every month for the last three months and his onc wanted to put him on
Xtandi
but we were unable to afford the co-pay of $3,000 (which is the negotiated price we were able to get the drug down to each month) so doc put him on ketoconazole and prednisone in October.
sweetudog
in
Advanced Prostate Cancer
6 years ago
Bipolar androgen therapy in men with metastatic castration-resistant prostate cancer after progression on enzalutamide.
And 5 out of 7 men achieved a 50% drop after
Xtandi
was resumed. Currently, BAT is a one-size-fits-all therapy. Men continue on Lupron, say, but receive monthly T injections ("testosterone cipionate 400 mg every 28 days until progression"). The T response is variable.
And 5 out of 7 men achieved a 50% drop after
Xtandi
was resumed. Currently, BAT is a one-size-fits-all therapy. Men continue on Lupron, say, but receive monthly T injections ("testosterone cipionate 400 mg every 28 days until progression"). The T response is variable.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Progression Report
My MedOnc, my husband and I had a good conversation about whether to start
Xtandi
. We concluded we would wait a few weeks with so much already changing at the moment.
My MedOnc, my husband and I had a good conversation about whether to start
Xtandi
. We concluded we would wait a few weeks with so much already changing at the moment.
YostConner
in
Advanced Prostate Cancer
6 years ago
Xtandi/Enzalutamide & Curcumin/Turmeric
More recently, Daddysdaughter: "My father is on
Xtandi
and he was told to stop taking tumeric because it decreases the effectiveness for the
Xtandi
.. he also was told to stop green tea." Rexwaterbury responded: "I am on
Xtandi
. Dr Myers also told me to stop turmeric."
More recently, Daddysdaughter: "My father is on
Xtandi
and he was told to stop taking tumeric because it decreases the effectiveness for the
Xtandi
.. he also was told to stop green tea." Rexwaterbury responded: "I am on
Xtandi
. Dr Myers also told me to stop turmeric."
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Tumeric - Good or Bad for Prostate Cancer?
Someone mentioned that tumeric might be contraindicated for anyone taking
xtandi
. Dr. Myers used to promote tumeric. Does anyone know what the contraindications are for tumeric? Does anyone know what the current thinking is about tumeric and prostate cancer?
Someone mentioned that tumeric might be contraindicated for anyone taking
xtandi
. Dr. Myers used to promote tumeric. Does anyone know what the contraindications are for tumeric? Does anyone know what the current thinking is about tumeric and prostate cancer?
cesanon
in
Advanced Prostate Cancer
6 years ago
ASCO Genitourinary Cancers Symposium (Olaparib and Durvalumab in metastatic castrate-resistant prostate cancer (mCRPC))
While most of us do not have hereditary BRCA mutations, men who ultimately fail Zytiga/
Xtandi
might nonetheless respond to Olaparib.
While most of us do not have hereditary BRCA mutations, men who ultimately fail Zytiga/
Xtandi
might nonetheless respond to Olaparib.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
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