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Venetoclax
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Bob Azopardi: My Clinical Trial Experience
Patient Power Founder, Andrew Schorr, interviewed Bob Azopardi, a 16-year CLL patient who participated in the Phase III arm of the
venetoclax
(Venclexta) clinical trial.
Patient Power Founder, Andrew Schorr, interviewed Bob Azopardi, a 16-year CLL patient who participated in the Phase III arm of the
venetoclax
(Venclexta) clinical trial.
mcints
in
CLL America Support
8 years ago
The Evolving CLL Treatment Landscape
Richard Furman to discuss the evolving CLL treatment landscape, including the introduction of
venetoclax
(Venclexta) to the CLL armamentarium.
Richard Furman to discuss the evolving CLL treatment landscape, including the introduction of
venetoclax
(Venclexta) to the CLL armamentarium.
mcints
in
CLL America Support
8 years ago
Dr Sharman's inaugural guest blog on Venclexta / Venetoclax / ABT-199, by Tom Boyd; Essential reading if you are considering this treatment
Considering treatment with Venclexta (or its myriad names) or Ibrurinib (and its myriad names) or ACP196/acalabrutinib (and I'm sure it will soon gain another name)? Then make certain that you first read this guest blog: http://www.cll-nhl.com/2016/04/venclexta.html Incidentally, I'd suggest that the
Considering treatment with Venclexta (or its myriad names) or Ibrurinib (and its myriad names) or ACP196/acalabrutinib (and I'm sure it will soon gain another name)? Then make certain that you first read this guest blog: http://www.cll-nhl.com/2016/04/venclexta.html Incidentally, I'd suggest that the
AussieNeil
Administrator
in
CLL Support
8 years ago
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Are there possibilities other than stem cell transplant in Canada for CLL with 11Q deletion?
His doctor never mentioned the new drug ABT-199
Venetoclax
. She went straight to the possibility of bone marrow transplant. I find this a bit shocking as there are a few new drugs on the market that I think she should first look into. Your input will be appreciated. Thanks. Karen
His doctor never mentioned the new drug ABT-199
Venetoclax
. She went straight to the possibility of bone marrow transplant. I find this a bit shocking as there are a few new drugs on the market that I think she should first look into. Your input will be appreciated. Thanks. Karen
karenmarie
in
CLL Support
8 years ago
CLL Patient Survey
If you have CLL and have been treated with either ibrutinib (Imbruvica) or
venetoclax
(ABT-199) you can help by completing our survey.
If you have CLL and have been treated with either ibrutinib (Imbruvica) or
venetoclax
(ABT-199) you can help by completing our survey.
LCAdmin
in
CLL Support
8 years ago
CLL Patient Survey
If you have CLL and have been treated with either ibrutinib (Imbruvica) or
venetoclax
(ABT-199) we need your help.
If you have CLL and have been treated with either ibrutinib (Imbruvica) or
venetoclax
(ABT-199) we need your help.
LCAdmin
Lymphoma Canada
in
Lymphoma Canada
8 years ago
Breaking News: Expert Perspective on Venclexta (venetoclax) Approval
http://www.patientpower.info/video/breaking-news-expert-perspective-on-venclexta-
venetoclax
-approval
http://www.patientpower.info/video/breaking-news-expert-perspective-on-venclexta-
venetoclax
-approval
mcints
in
CLL America Support
8 years ago
What Could a New Drug Approval Mean for CLL Patients?
William Wierda, medical director of the Department of Leukemia at the University of Texas MD Anderson Cancer Center, joins Patient Power to discuss the FDA approval of Venclexta (
venetoclax
) for use in CLL patients with the 17p deletion. Dr.
William Wierda, medical director of the Department of Leukemia at the University of Texas MD Anderson Cancer Center, joins Patient Power to discuss the FDA approval of Venclexta (
venetoclax
) for use in CLL patients with the 17p deletion. Dr.
mcints
in
CLL America Support
8 years ago
Venetoclax in Relapsed deletion 17 CLL
We discussed his late breaking abstract on
venetoclax
in refractory CLL patients with deletion 17p. You can see a summary and view our interview here.
We discussed his late breaking abstract on
venetoclax
in refractory CLL patients with deletion 17p. You can see a summary and view our interview here.
bkoffman
CLL CURE Hero
in
CLL Support
8 years ago
ASH 2015: Dr. Jones on combining venetoclax with obinutuzumab, and details about the LRF meeting this weekend and new CLL support groups
We discussed the data for patients with relapsed/refractory CLL on combining the BCL-2 (B-cell lymphoma-2) inhibitor
venetoclax
with the antibody obinutuzumab, the ongoing European trials and a new study that adds ibrutinib to that mix. You can see a summary and view our interview here.
We discussed the data for patients with relapsed/refractory CLL on combining the BCL-2 (B-cell lymphoma-2) inhibitor
venetoclax
with the antibody obinutuzumab, the ongoing European trials and a new study that adds ibrutinib to that mix. You can see a summary and view our interview here.
bkoffman
CLL CURE Hero
in
CLL Support
8 years ago
The new CLL drug
It was reported today a new Cll drug
Venetoclax
in trials cured 78% of trial personell in trial. The drug was given to terminal cases with the drug leaving no trace of cancer in blood.
It was reported today a new Cll drug
Venetoclax
in trials cured 78% of trial personell in trial. The drug was given to terminal cases with the drug leaving no trace of cancer in blood.
brad8
in
CLL Support
8 years ago
Husband with p53 deletion
Recently I read an article about
Venetoclax
clinical trials which sound promising for aggressive disease which I am going to ask the Dr about when we go back in February. Just wondering if any of you have had any experience with p53 deletions and what exactly this means for us for the future?
Recently I read an article about
Venetoclax
clinical trials which sound promising for aggressive disease which I am going to ask the Dr about when we go back in February. Just wondering if any of you have had any experience with p53 deletions and what exactly this means for us for the future?
MichRae
in
CLL Support
8 years ago
Sharing the good news
This study compares
Venetoclax
in combination with Rituximab against Bedamustine in combination with Rituximab (Murano study). After some research on the internet, we decided to attend this trial. After some medical checks I started in August with a very low daily dosis of 20mg
Venetoclax
.
This study compares
Venetoclax
in combination with Rituximab against Bedamustine in combination with Rituximab (Murano study). After some research on the internet, we decided to attend this trial. After some medical checks I started in August with a very low daily dosis of 20mg
Venetoclax
.
Korstiaan
in
CLL Support
8 years ago
Venetoclax (ABT-199) response rate on del 17p CLL patients (ASH 2015)
Venetoclax
is an orally bioavailable, selective BCL-2 inhibitor that induces apoptosis in CLL cells independent of p53. A phase 1 study of
Venetoclax
showed high response rates in patients with relapsed/refractory CLL, including del(17p) CLL (overall response rate, ORR = 77%).
Venetoclax
is an orally bioavailable, selective BCL-2 inhibitor that induces apoptosis in CLL cells independent of p53. A phase 1 study of
Venetoclax
showed high response rates in patients with relapsed/refractory CLL, including del(17p) CLL (overall response rate, ORR = 77%).
AussieNeil
Administrator
in
CLL Support
8 years ago
The Role of BCL2 Inhibition in CLL
Friends, To understand why BCL-2 is such an attractive target in CLL and with the promise of
venetoclax
(ABT-199) hopefully coming soon, here is the very easy to digest nine minute lecture given by Dr.
Friends, To understand why BCL-2 is such an attractive target in CLL and with the promise of
venetoclax
(ABT-199) hopefully coming soon, here is the very easy to digest nine minute lecture given by Dr.
bkoffman
CLL CURE Hero
in
CLL Support
9 years ago
Integrating Emerging Evidence Into the Management of CLL Patients; what leading CLL experts recommend in 4 case studies
(Second Generation BCL-2 inhibitor)
Venetoclax
+ Rituximab and of course..
(Second Generation BCL-2 inhibitor)
Venetoclax
+ Rituximab and of course..
AussieNeil
Administrator
in
CLL Support
9 years ago
The Future Role of FCR and new data on venetoclax and rituximab
We also share my comments and background on an important oral abstract presented at the 20th Congress of the European Hematology Association (EHA), June 11-15, 2015 on
venetoclax
(ABT-199 or GDC-199) and rituximab.
We also share my comments and background on an important oral abstract presented at the 20th Congress of the European Hematology Association (EHA), June 11-15, 2015 on
venetoclax
(ABT-199 or GDC-199) and rituximab.
bkoffman
CLL CURE Hero
in
CLL Support
9 years ago
For Refractory CLL, Venetoclax's (ABT-199's) Complete Response Rate Is Tops
The complete response rate seen with
venetoclax
is especially notable, said lead investigator Andrew W. Roberts, MBBS, PhD, from the Royal Melbourne Hospital and Walter and Eliza Hall Institute of Medical Research, in Australia."
The complete response rate seen with
venetoclax
is especially notable, said lead investigator Andrew W. Roberts, MBBS, PhD, from the Royal Melbourne Hospital and Walter and Eliza Hall Institute of Medical Research, in Australia."
AussieNeil
Administrator
in
CLL Support
9 years ago
Venetoclax (ABT-199) Receives Breakthrough Therapy Designation In Relapsed Or Refractory CLL In Previously Treated 17p deletion Patients
This breakthrough designation - only for relapsed/refractory 17p deletion patients should mean the path to FDA approval will be smooth and short in the USA. This is very good news for my fellow American patients with 17p del. Hope the rest of the world stays in step. We are only going to beat this cancer
This breakthrough designation - only for relapsed/refractory 17p deletion patients should mean the path to FDA approval will be smooth and short in the USA. This is very good news for my fellow American patients with 17p del. Hope the rest of the world stays in step. We are only going to beat this cancer
bkoffman
CLL CURE Hero
in
CLL Support
9 years ago
Assessing Response With Novel Agents in CLL - OncLive Peer Exchange
Kipps, MD, UCSD; Shuo Ma, MD, PhD, Northwestern http://www.onclive.com/peer-exchange/non-hodgkins-lymphoma/Assessing-the-Utility-of-MRD-Measures-Versus-CT-Scans The discussion covers: - Inhibition of Rituximab by Ibrutinib - ABT-199 (
Venetoclax
) - ABT-199's remarkable ability to get complete remission
Kipps, MD, UCSD; Shuo Ma, MD, PhD, Northwestern http://www.onclive.com/peer-exchange/non-hodgkins-lymphoma/Assessing-the-Utility-of-MRD-Measures-Versus-CT-Scans The discussion covers: - Inhibition of Rituximab by Ibrutinib - ABT-199 (
Venetoclax
) - ABT-199's remarkable ability to get complete remission
AussieNeil
Administrator
in
CLL Support
9 years ago
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