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Venclexta
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CLL - Venclexta/Gazyva do’s and dont’s
This may be an asinine question, but can I assume alcohol of any amount should be avoided with this treatment plan? Thanks.
This may be an asinine question, but can I assume alcohol of any amount should be avoided with this treatment plan? Thanks.
msccsm11
in
CLL Support
4 years ago
Venetoclax plus obinutuzumab - the first chemotherapy-free, fixed-duration first line CLL treatment approved by Health Canada
[i] *
VENCLEXTA
® (venetoclax) plus obinutuzumab is the first chemotherapy-free, fixed-duration combination regimen approved by Health Canada for patients with previously untreated chronic lymphocytic leukemia (CLL).
[i] *
VENCLEXTA
® (venetoclax) plus obinutuzumab is the first chemotherapy-free, fixed-duration combination regimen approved by Health Canada for patients with previously untreated chronic lymphocytic leukemia (CLL).
AussieNeil
Partner
in
CLL Support
4 years ago
Three-drug GIV combo promising against high-risk CLL - Patients with deletion 17p or TP53 (from EHA Congress)
[i]For patients with high-risk chronic lymphocytic leukemia (CLL), first-line therapy with a triple combination of targeted agents obinutuzumab (Gazyva), ibrutinib (Imbruvica), and venetoclax (
Venclexta
) showed encouraging response rates in the phase 2 CLL2-GIVe trial.
[i]For patients with high-risk chronic lymphocytic leukemia (CLL), first-line therapy with a triple combination of targeted agents obinutuzumab (Gazyva), ibrutinib (Imbruvica), and venetoclax (
Venclexta
) showed encouraging response rates in the phase 2 CLL2-GIVe trial.
AussieNeil
Partner
in
CLL Support
4 years ago
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Time-Limited Triplet Emerges as a Potential Standard in Relapsed/Refractory CLL
Oncology live May 06, 2020 [i]The time-limited triplet of umbralisib, ublituximab, and venetoclax (
Venclexta
) could potentially become a standard of care for patients with relapsed/refractory chronic lymphocytic leukemia (CLL) who have progressed on frontline BTK inhibition, according to Paul M.
Oncology live May 06, 2020 [i]The time-limited triplet of umbralisib, ublituximab, and venetoclax (
Venclexta
) could potentially become a standard of care for patients with relapsed/refractory chronic lymphocytic leukemia (CLL) who have progressed on frontline BTK inhibition, according to Paul M.
Jm954
Administrator
in
CLL Support
4 years ago
Venclexta 600 mg
Is anyone on 600 mg of
Venclexta
? My father is on
Venclexta
for almost two years now. Rituxan one infusion every three months was added in January 2019 after signs of progression. Prior to that he was on Imbruvica, that kept him in remission for four years.
Is anyone on 600 mg of
Venclexta
? My father is on
Venclexta
for almost two years now. Rituxan one infusion every three months was added in January 2019 after signs of progression. Prior to that he was on Imbruvica, that kept him in remission for four years.
Aliona06
in
CLL Support
4 years ago
Azacitidine and Venclexta
How long have you been on
Venclexta
?
How long have you been on
Venclexta
?
Cliffsails
in
CLL Support
4 years ago
Frontline Venetoclax/Obinutuzumab Approved in Europe for CLL
In some welcome good news[i], "The European Commission has approved a fixed-dose combination of venetoclax (
Venclexta
) and obinutuzumab (Gazyva) for the treatment of patients with previously untreated chronic lymphocytic leukemia (CLL)"[/i] https://www.onclive.com/web-exclusives/frontline-venetoclaxobinutuzumab-approved-in-europe-in-cll
In some welcome good news[i], "The European Commission has approved a fixed-dose combination of venetoclax (
Venclexta
) and obinutuzumab (Gazyva) for the treatment of patients with previously untreated chronic lymphocytic leukemia (CLL)"[/i] https://www.onclive.com/web-exclusives/frontline-venetoclaxobinutuzumab-approved-in-europe-in-cll
AussieNeil
Partner
in
CLL Support
4 years ago
First filling for me january 7 Venclexta 400 mg number 120 Medicare part D
I have written several posts over the year about how part D works. In january it always does a hard reset so the first payment is a combination of the deductible/co-insurance to donut hole/ then finally to the catastrophic part where the cost becomes 5 percent. the biggest payment by far is the first
I have written several posts over the year about how part D works. In january it always does a hard reset so the first payment is a combination of the deductible/co-insurance to donut hole/ then finally to the catastrophic part where the cost becomes 5 percent. the biggest payment by far is the first
Hidden
in
CLL Support
4 years ago
Please share experience of venetoclax plus obinutuzimab or acalabrutinib mono treatment in an important survey
Venetoclax (
Venclexta
) + obinutuzumab (Gazyva) for first-line treatment of CLL/SLL Acalabrutinib (Calquence) + obinutuzumab (Gazyva) for first-line treatment of CLL/SLL Acalabrutinib (Calquence) monotherapy for first-line treatment of CLL/SLL Acalabrutinib (Calquence) monotherapy for treatment of relapsed
Venetoclax (
Venclexta
) + obinutuzumab (Gazyva) for first-line treatment of CLL/SLL Acalabrutinib (Calquence) + obinutuzumab (Gazyva) for first-line treatment of CLL/SLL Acalabrutinib (Calquence) monotherapy for first-line treatment of CLL/SLL Acalabrutinib (Calquence) monotherapy for treatment of relapsed
Jm954
Administrator
in
CLL Support
4 years ago
Please share experience of venetoclax plus obinutuzimab or acalabrutinib treatment in a survey that may help others gain access?
survey-for-cll-patients-having-taken-venetoclax-or-acalabrutinib IF YOU ARE IN THE UK OR IN COUNTRIES OUTSIDE OF CANADA AND HAVE BEEN TREATED WITH OR ARE IN TREATMENT WITH ONE OF THE TREATMENTS BELOW YOU CAN HELP BY COMPLETING THIS SURVEY: https://www.surveymonkey.com/r/CLLCAN2020 1.Venetoclax (
Venclexta
survey-for-cll-patients-having-taken-venetoclax-or-acalabrutinib IF YOU ARE IN THE UK OR IN COUNTRIES OUTSIDE OF CANADA AND HAVE BEEN TREATED WITH OR ARE IN TREATMENT WITH ONE OF THE TREATMENTS BELOW YOU CAN HELP BY COMPLETING THIS SURVEY: https://www.surveymonkey.com/r/CLLCAN2020 1.Venetoclax (
Venclexta
HAIRBEAR_UK
Administrator
in
CLL Support
4 years ago
venclexta and Imbruvica both owned by same company
Just for thought- i copied a paragraph from an article i read The study was supported by AbbVie, the manufacturer of venetoclax. AbbVie also owns Pharmacyclics, the manufacturer of ibrutinib . Several authors report relationships with industry, including AbbVie, as detailed in the article. Wiestner
Just for thought- i copied a paragraph from an article i read The study was supported by AbbVie, the manufacturer of venetoclax. AbbVie also owns Pharmacyclics, the manufacturer of ibrutinib . Several authors report relationships with industry, including AbbVie, as detailed in the article. Wiestner
Hidden
in
CLL Support
5 years ago
Survey for CLL patients having taken Venetoclax or Acalabrutinib
CLL/SLL Patient Survey If you have CLL or SLL and have been treated with the following therapies, you can help by completing our survey: Venetoclax (
Venclexta
) + obinutuzumab (Gazyva) for first-line treatment of CLL/SLL Acalabrutinib (Calquence) with or without obinutuzumab (Gazyva) for first-line
CLL/SLL Patient Survey If you have CLL or SLL and have been treated with the following therapies, you can help by completing our survey: Venetoclax (
Venclexta
) + obinutuzumab (Gazyva) for first-line treatment of CLL/SLL Acalabrutinib (Calquence) with or without obinutuzumab (Gazyva) for first-line
cllpag_canada
in
CLL Support
4 years ago
Dr Mary Ann Anderson on CLL, Venetoclax and future trends in CLL management
: We chatted to her at the Leukaemia Foundation’s Blood Cancer Conference in Melbourne in October 2018 about her involvement in pioneering the drug, venetoclax (
Venclexta
®) as a breakthrough treatment for CLL.
: We chatted to her at the Leukaemia Foundation’s Blood Cancer Conference in Melbourne in October 2018 about her involvement in pioneering the drug, venetoclax (
Venclexta
®) as a breakthrough treatment for CLL.
AussieNeil
Partner
in
CLL Support
5 years ago
MRD on 200 mg venetoclax (venclexta)
I asked before whether anyone was on 200 mg of venetoclax, and a number of people said yes (due to side effects). I am now wondering whether anyone on 200 mg achieved MRD negative status.
I asked before whether anyone was on 200 mg of venetoclax, and a number of people said yes (due to side effects). I am now wondering whether anyone on 200 mg achieved MRD negative status.
profrich
in
CLL Support
5 years ago
POST BMT 1-Year & 7 Months, BOY OH BOY!!!
/Nov. 2016 and treated with
Venclexta
and 4 infusions of Rituxan Nov. 2017 Bone Marrow Transplant Relapsed Dec. 2018 currently back on
Venclexta
When we arrived at our 1-year anniversary post BMT – everything was going well.
/Nov. 2016 and treated with
Venclexta
and 4 infusions of Rituxan Nov. 2017 Bone Marrow Transplant Relapsed Dec. 2018 currently back on
Venclexta
When we arrived at our 1-year anniversary post BMT – everything was going well.
NMMP
in
CLL Support
5 years ago
Dr. Shadman on Fixed Durations of Treatment in CLL
However, this is not a guarantee because studies, such as CLL14 or MURANO, were designed to give venetoclax (
Venclexta
) in combination with a CD20-targeted antibody for 1 and 2 years, respectively. It is not yet known what happens after these patients stop treatment.
However, this is not a guarantee because studies, such as CLL14 or MURANO, were designed to give venetoclax (
Venclexta
) in combination with a CD20-targeted antibody for 1 and 2 years, respectively. It is not yet known what happens after these patients stop treatment.
Jm954
Administrator
in
CLL Support
5 years ago
V + O frontline approved by FDA
https://news.abbvie.com/news/press-releases/abbvie-announces-us-fda-approval-
venclexta
-venetoclax-as-chemotherapy-free-combination-regimen-for-previously-untreated-chronic-lymphocytic-leukemia-patients.htm
https://news.abbvie.com/news/press-releases/abbvie-announces-us-fda-approval-
venclexta
-venetoclax-as-chemotherapy-free-combination-regimen-for-previously-untreated-chronic-lymphocytic-leukemia-patients.htm
avzuclav
in
CLL Support
5 years ago
Clinical trial results & reviews of new treatments for CLL written in easy to understand terms
id=31288 - Here is a sample of the Ibrutinib and Venetoclax write up: [i] Combining ibrutinib and venetoclax for first-time treatment of chronic lymphocytic leukemia - In a nutshell This study wanted to research if the combination therapy of ibrutinib (Imbruvica) and venetoclax (
Venclexta
) was effective
id=31288 - Here is a sample of the Ibrutinib and Venetoclax write up: [i] Combining ibrutinib and venetoclax for first-time treatment of chronic lymphocytic leukemia - In a nutshell This study wanted to research if the combination therapy of ibrutinib (Imbruvica) and venetoclax (
Venclexta
) was effective
lankisterguy
Volunteer
in
CLL Support
5 years ago
imbruvica/gazyva or imbruvica/venclexta
I am b-pll. i am p17 deletion and p53 mutated. I get treated like advanced CLL because there are so few b-pll patients not enough to get drug indications approved. Conventional pre novel drug era drugs are mostly resistant. i have been on Imbruvica for 3 months and have had dramatic improvement. I
I am b-pll. i am p17 deletion and p53 mutated. I get treated like advanced CLL because there are so few b-pll patients not enough to get drug indications approved. Conventional pre novel drug era drugs are mostly resistant. i have been on Imbruvica for 3 months and have had dramatic improvement. I
Hidden
in
CLL Support
5 years ago
AHA--autoimmune hemolytic anemia
My husband is on
Venclexta
and has developed autoimmune hemolytic anemia for the second time (first time was when he was on Ibrutinib). First treatment was prednisone and he had a tough time getting off of it--even very gradually.
My husband is on
Venclexta
and has developed autoimmune hemolytic anemia for the second time (first time was when he was on Ibrutinib). First treatment was prednisone and he had a tough time getting off of it--even very gradually.
kulachick
in
CLL Support
5 years ago
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