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Transurethral resection of the prostate (TURP)
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Dutasteride Monotherapy is effective for Newly Diagnosed PCa men not on ADT
This plot shows men that either don't have PCa (Group A) or newly diagnosed men with PCa by biopsy (Group B). Neither group is on ADT. Dutasteride monotherapy (0.5 mg/day) causes an average drop in PSA of about 50% in both Groups, and an average drop of about 20% in prostate volume. In one man, his
This plot shows men that either don't have PCa (Group A) or newly diagnosed men with PCa by biopsy (Group B). Neither group is on ADT. Dutasteride monotherapy (0.5 mg/day) causes an average drop in PSA of about 50% in both Groups, and an average drop of about 20% in prostate volume. In one man, his
janebob99
in
Prostate Cancer Network
3 months ago
Declining red blood cells.
This Poollover, and I'm stage 4 prostrate cancer. My anemia is slowly getting worse. I'm on Orgovyx and Zytiga which brought my PSA to 0.78 from 12. Where do I go from here. In June I'll be 87. Terry
This Poollover, and I'm stage 4 prostrate cancer. My anemia is slowly getting worse. I'm on Orgovyx and Zytiga which brought my PSA to 0.78 from 12. Where do I go from here. In June I'll be 87. Terry
Poollover
in
Advanced Prostate Cancer
3 months ago
Low PSA + high Gleason-FYI
I’ve just heard that this is a thing. Unfortunately it seems to affect my outcome. For instance, I had an initial PSA of 4.8 (4.6 after retesting), and I’m Gleason 9. Three of my doctors have mentioned it to me in passing (most recently today), which led me to Google it. https://www.ncbi.nlm.nih.gov
I’ve just heard that this is a thing. Unfortunately it seems to affect my outcome. For instance, I had an initial PSA of 4.8 (4.6 after retesting), and I’m Gleason 9. Three of my doctors have mentioned it to me in passing (most recently today), which led me to Google it. https://www.ncbi.nlm.nih.gov
Jpburns
in
Advanced Prostate Cancer
4 months ago
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Dutssteride increases PSA Doubling Time by 2X for men with PSA Failure.
These two Kaplan-Meier plots compare Dutasteride (0.5 mg/day) to Placebo in a randomized, double-blind trial from 2012 of 187 men who have progressed to
PSA Failure.
In the upper plot, Dutasteride increases the
Doubling Time
from, for example, 9 months to 18 months (factor of 2X). In
These two Kaplan-Meier plots compare Dutasteride (0.5 mg/day) to Placebo in a randomized, double-blind trial from 2012 of 187 men who have progressed to
PSA Failure.
In the upper plot, Dutasteride increases the
Doubling Time
from, for example, 9 months to 18 months (factor of 2X). In
janebob99
in
Prostate Cancer Network
3 months ago
Dutasteride increases PSA Doubling Time after PSA Recurrence
These two Kaplan-Meier plots compare Dutasteride (0.5 mg/day) to Placebo in a randomized, double-blind trial from 2012 of 187 men who have progressed to
PSA Failure.
In the upper plot, Dutasteride increases the
Doubling Time
from, for example, 9 months to 18 months (factor of 2X). In
These two Kaplan-Meier plots compare Dutasteride (0.5 mg/day) to Placebo in a randomized, double-blind trial from 2012 of 187 men who have progressed to
PSA Failure.
In the upper plot, Dutasteride increases the
Doubling Time
from, for example, 9 months to 18 months (factor of 2X). In
janebob99
in
Advanced Prostate Cancer
3 months ago
High PSA upon diagnosis, treatment , and outcome
Hello, Diagnosed 9 months ago with Gleason 7 unfavorable… 2 4+3 ,2 3+4, and 1 3+3 ..on one side only ..I guess my high PSA score made it unfavorable , PSA 18. As a result had aggressive tri modality treatment .. brachytherapy seeds, 15 linac radiation sessions, and 9 months o ADT ..just stopped
Hello, Diagnosed 9 months ago with Gleason 7 unfavorable… 2 4+3 ,2 3+4, and 1 3+3 ..on one side only ..I guess my high PSA score made it unfavorable , PSA 18. As a result had aggressive tri modality treatment .. brachytherapy seeds, 15 linac radiation sessions, and 9 months o ADT ..just stopped
Yokohama2023
in
Prostate Cancer Network
3 months ago
It's Back!
This post should be good for newbies also. This should show you guys how long you can go!Anyways, 13 years ago I was diagnosed with PCA Gleason 7 PSA 44. With spread outside of prostate. Did 39 treatments off radiation and have been mostly on ADT for the duration except during COVID I took a break
This post should be good for newbies also. This should show you guys how long you can go!Anyways, 13 years ago I was diagnosed with PCA Gleason 7 PSA 44. With spread outside of prostate. Did 39 treatments off radiation and have been mostly on ADT for the duration except during COVID I took a break
Tjc1
in
Advanced Prostate Cancer
4 months ago
updated scans post chemo
My dad has done 2 rounds of chemo, the third was delayed by hospitalization for sepsis. He has also had 10 rounds of radiation. His third round will be near Christmas and they completed scans to compare to his pre chemo scans. His full body bone scans state the following “Diffuse skeletal metastatic
My dad has done 2 rounds of chemo, the third was delayed by hospitalization for sepsis. He has also had 10 rounds of radiation. His third round will be near Christmas and they completed scans to compare to his pre chemo scans. His full body bone scans state the following “Diffuse skeletal metastatic
StayingSTRNG
in
Advanced Prostate Cancer
6 months ago
Lupron and prostate cancer
hi everyone. im a 67 year old man taking Lupron hormone deprivation for prostate cancer. i finished receiving 20 external beam radiation treatments in August 2023. the Lupron injections are quarterly and will continue for 18-24 months. my interest in sex has completely dropped off. i assume this is normal
hi everyone. im a 67 year old man taking Lupron hormone deprivation for prostate cancer. i finished receiving 20 external beam radiation treatments in August 2023. the Lupron injections are quarterly and will continue for 18-24 months. my interest in sex has completely dropped off. i assume this is normal
rolex1951
in
Advanced Prostate Cancer
6 months ago
Barry
Hi, stage 4 prostate cancer 9 months in on anti testerone injections degatelix psa level has risen from 77 to 323, what are my chances?
Hi, stage 4 prostate cancer 9 months in on anti testerone injections degatelix psa level has risen from 77 to 323, what are my chances?
littlemount
in
Advanced Prostate Cancer
5 months ago
advice re 0.02 reading
Hi everyone my first ever psa age 53 no symptoms 3.1 jan 2022 mri pri 3 hard prostate Gleason 3+3 no other scans mri did not detect the size of tumour l was told to go on active surveillance My brain said no ,choice given to me was remove prostate or brachytherapy l had operation in May 2022 all good
Hi everyone my first ever psa age 53 no symptoms 3.1 jan 2022 mri pri 3 hard prostate Gleason 3+3 no other scans mri did not detect the size of tumour l was told to go on active surveillance My brain said no ,choice given to me was remove prostate or brachytherapy l had operation in May 2022 all good
Ffghytrrg
in
Advanced Prostate Cancer
5 months ago
PSA rising 10 weeks after Orgovyx Holiday
PCA diagnosed 2018, PSA 6.7, GS 9 (lesions in both lobes of gland, no evidence of metastases), EBRT + Firmagon ADT treatment, ended spring 2019, PSA nadir <0.02 Nov 2019 before rising again. BCR 2022-2023, Pylarify PSMA, Nov 2022 and March 2023 indicates intense uptake areas visible again in the
PCA diagnosed 2018, PSA 6.7, GS 9 (lesions in both lobes of gland, no evidence of metastases), EBRT + Firmagon ADT treatment, ended spring 2019, PSA nadir <0.02 Nov 2019 before rising again. BCR 2022-2023, Pylarify PSMA, Nov 2022 and March 2023 indicates intense uptake areas visible again in the
ac61418
in
Advanced Prostate Cancer
5 months ago
Am i catastrophizing over my results
Hi. I’m a little confused over my situation.After Cyberknife treatment and two years on ADT with a constant PSA of 0.02 post treatment .My PSA started to rise and at 4.1 approximately I had a PSMA scan my second .i also had one 3 years previous to that and both were clear . My MO has me back on ADT
Hi. I’m a little confused over my situation.After Cyberknife treatment and two years on ADT with a constant PSA of 0.02 post treatment .My PSA started to rise and at 4.1 approximately I had a PSMA scan my second .i also had one 3 years previous to that and both were clear . My MO has me back on ADT
Walliam
in
Advanced Prostate Cancer
5 months ago
2Nd Biopsy in 3+ years of Bone Met
Greetings All, A question about biopsies: Upon PC-stage 4 diagnosis per discovery of pc lesions causing spinal compression in 2020, my husband had a biopsy taken during his back surgery-which showed his already metastatic pc not to be an inherited condition. He went on to radiation of the spinal
Greetings All, A question about biopsies: Upon PC-stage 4 diagnosis per discovery of pc lesions causing spinal compression in 2020, my husband had a biopsy taken during his back surgery-which showed his already metastatic pc not to be an inherited condition. He went on to radiation of the spinal
Lavender22
in
Advanced Prostate Cancer
3 months ago
Post Docetaxel scan, which one?
68yrs. Gleeson 5+4 T2cN1M0 Cap Sept 2023. PSA at diagnosis 27. mpMRI at diagnosis pirades V2= 2! Small prostate volume 22mls ( have been on Dutasteride) CT at diagnosis minimally prominent left pelvic wall nodes nil else. F18 PSMA Sept 2023 : pelvic lymph nodes + para aortic nodes, highest lymph
68yrs. Gleeson 5+4 T2cN1M0 Cap Sept 2023. PSA at diagnosis 27. mpMRI at diagnosis pirades V2= 2! Small prostate volume 22mls ( have been on Dutasteride) CT at diagnosis minimally prominent left pelvic wall nodes nil else. F18 PSMA Sept 2023 : pelvic lymph nodes + para aortic nodes, highest lymph
Jay-kud8
in
Advanced Prostate Cancer
1 year ago
PSA and Eligard and bicalutamide
My PSA keep rising. Today, PSA went up to 1.1 (Today-03/13/24) from 0.37 (January). Doctor told me to take another Eljgard injection next week. This is the 2nd time. Doctor asked me to stop taking bicalutamide and dutasteride, as they appear not to be effective any longer. He said I solely rely
My PSA keep rising. Today, PSA went up to 1.1 (Today-03/13/24) from 0.37 (January). Doctor told me to take another Eljgard injection next week. This is the 2nd time. Doctor asked me to stop taking bicalutamide and dutasteride, as they appear not to be effective any longer. He said I solely rely
Domas
in
Advanced Prostate Cancer
3 months ago
225Ac-J591 Yields Responses in Difficult-to-Treat Metastatic Prostate Cancer
It seems to work better on visceral and bone metastatis... https://www.cancertherapyadvisor.com/home/news/conference-coverage/suo-2023/225ac-j591-yields-responses-in-difficult-to-treat-metastatic-prostate-cancer/
It seems to work better on visceral and bone metastatis... https://www.cancertherapyadvisor.com/home/news/conference-coverage/suo-2023/225ac-j591-yields-responses-in-difficult-to-treat-metastatic-prostate-cancer/
Maxone73
in
Advanced Prostate Cancer
6 months ago
Persistent PSA
3/23 Prostatectomy PSA pre-op 4.8 Gleason 4+4, epe: present, lymphnodes removed and clear 4/23. PSA: 0.21 7/23 PSA: 0.22 8/23. PSA: 0.32 9/23 39 rounds of IMRT, ending 11/23 1/24. PSA: 0.32 3/24 PSA: 0.39 PSMA PET scan shows no evidence of recurrence or metastatic disease
3/23 Prostatectomy PSA pre-op 4.8 Gleason 4+4, epe: present, lymphnodes removed and clear 4/23. PSA: 0.21 7/23 PSA: 0.22 8/23. PSA: 0.32 9/23 39 rounds of IMRT, ending 11/23 1/24. PSA: 0.32 3/24 PSA: 0.39 PSMA PET scan shows no evidence of recurrence or metastatic disease
Nonno
in
Prostate Cancer Network
3 months ago
Recurrence after prostatectomy
I have a relative who had surgery 6.5 years ago. Pathology was very favorable, 3+3+tertiary 4 i.e. less than 5%, no pos margins, no ECE, no nodes. He remained undetectable for 6.5 years, but now is .07 verified. What would SOC be for him? Prostate bed or wide radiation, length of ADT, just Lupron or
I have a relative who had surgery 6.5 years ago. Pathology was very favorable, 3+3+tertiary 4 i.e. less than 5%, no pos margins, no ECE, no nodes. He remained undetectable for 6.5 years, but now is .07 verified. What would SOC be for him? Prostate bed or wide radiation, length of ADT, just Lupron or
Fred312
in
Advanced Prostate Cancer
6 months ago
liver resection - nearly 3 years on
hi, I had my liver resection in sept 2020 due to a large liver adenoma (tumour) inside that had ruptured (unknown to me that it existed). Nearly 3 years on, I still get so much pain around my scar which is all the way across my abdomen. In the last few months, my pain has been particularly bad around
hi, I had my liver resection in sept 2020 due to a large liver adenoma (tumour) inside that had ruptured (unknown to me that it existed). Nearly 3 years on, I still get so much pain around my scar which is all the way across my abdomen. In the last few months, my pain has been particularly bad around
SurvivorPhoenix
in
ICUsteps
1 year ago
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