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TMPRSS2 & COVID-19
TMPRSS2-ERG gene fusion status was also associated with an enhanced androgen-regulated gene expression, along with altered intratumoral androgen metabolism, demonstrated by reduced
testosterone
concentrations and increased DHT/
testosterone
ratios in TMPRSS2-ERG-positive tumors.
TMPRSS2-ERG gene fusion status was also associated with an enhanced androgen-regulated gene expression, along with altered intratumoral androgen metabolism, demonstrated by reduced
testosterone
concentrations and increased DHT/
testosterone
ratios in TMPRSS2-ERG-positive tumors.
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Decision Matrix Conundrum
My other question is whether using estradiol (alone or with other ADT such as degarelix) would afford the same benefit via TMPRSS2 in men with PC, as women have increased rather than decreased TMPRSS2 from
testosterone
suppression apparently. It gets curiouser and curiouser.
My other question is whether using estradiol (alone or with other ADT such as degarelix) would afford the same benefit via TMPRSS2 in men with PC, as women have increased rather than decreased TMPRSS2 from
testosterone
suppression apparently. It gets curiouser and curiouser.
MateoBeach
in
Advanced Prostate Cancer
4 years ago
Is there anything I can take for high testosterone
Recommendations
Recommendations
Rjt7
in
PCOS UK (Verity)
4 years ago
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Positive APC Treatment
PSA went from 39 to 0.01 and
Testosterone
bottomed out at 8. Throughout the 4 years I have maintained my daily visits to LA Fitness although doing less, but always walking 2 miles. So happy that I had the will power to keep the blood circulating and muscles used.
PSA went from 39 to 0.01 and
Testosterone
bottomed out at 8. Throughout the 4 years I have maintained my daily visits to LA Fitness although doing less, but always walking 2 miles. So happy that I had the will power to keep the blood circulating and muscles used.
Wdoug
in
Advanced Prostate Cancer
4 years ago
Female Hormones
Also, my
testosterone
level is high and I'm not too sure what could cause this. Below are all of my results along with the ranges: SHBG range: 32.4 - 128nmol/L. My result: 47.1nmol/L.
Also, my
testosterone
level is high and I'm not too sure what could cause this. Below are all of my results along with the ranges: SHBG range: 32.4 - 128nmol/L. My result: 47.1nmol/L.
rachelvmears
in
Women's Health
4 years ago
Blood Test Results - please advise
I've asked for a retest for Calcium and
Testosterone
at the hospital but can't get it done yet. I am currently on 75mg Levo and 1/2 grain of ERFA Thyroid NDT. The free T3 is actually lower than when I was on 100mg of Levo so I am really confused and puzzled as I thought it would be higher.
I've asked for a retest for Calcium and
Testosterone
at the hospital but can't get it done yet. I am currently on 75mg Levo and 1/2 grain of ERFA Thyroid NDT. The free T3 is actually lower than when I was on 100mg of Levo so I am really confused and puzzled as I thought it would be higher.
jostafford0
in
Thyroid UK
4 years ago
Stony Brook Estrogen Trial for COVID-19.
I recently mentioned that
testosterone
was an immunosuppressor & that there might be a COVID survival advantage for males with
testosterone
[T] below 350 ng/dL, say. But when T approaches zero, so does estradiol [E2], because E2 is created from T via the aromatase enzyme.
I recently mentioned that
testosterone
was an immunosuppressor & that there might be a COVID survival advantage for males with
testosterone
[T] below 350 ng/dL, say. But when T approaches zero, so does estradiol [E2], because E2 is created from T via the aromatase enzyme.
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Trying to Make Sense of Husbands Testosterone History and Wanting to Clarify Why a Doctor Feels He May Be Becoming CR.
But looking back at 252 being his normal, could the pelvic radiation have caused damage to his
testosterone
production? Or is his
Testosterone
still recovering from Lupron he stopped 10 months ago?
But looking back at 252 being his normal, could the pelvic radiation have caused damage to his
testosterone
production? Or is his
Testosterone
still recovering from Lupron he stopped 10 months ago?
paige20180
in
Advanced Prostate Cancer
4 years ago
Is it crpc after 22 months of diagnose?
My psa has risen from 0.08 on 4 Jan 2020 to 0.972 ng/dl on 23 Rd april 2020 with
testosterone
level 9..I am on bicalutamide 50 mg od frm last 22 month..psa at time of diagnosis was 111ng/dl ; Gleason score was 3+4; and was metastized to inferior iliac spine at the time of diagnosis, no new spots of Mets
My psa has risen from 0.08 on 4 Jan 2020 to 0.972 ng/dl on 23 Rd april 2020 with
testosterone
level 9..I am on bicalutamide 50 mg od frm last 22 month..psa at time of diagnosis was 111ng/dl ; Gleason score was 3+4; and was metastized to inferior iliac spine at the time of diagnosis, no new spots of Mets
Rafithussain
in
Advanced Prostate Cancer
4 years ago
Is 0.012(3months post op) PSA to 0.024 after 6 months a significant rise?
I assume
testosterone
levels would rise after doing nothing to being up to 8 hours a day on feet and lifting heavy objects. Would this be relevant in PSA rising and have little to do with future recurrence? Thanks!
I assume
testosterone
levels would rise after doing nothing to being up to 8 hours a day on feet and lifting heavy objects. Would this be relevant in PSA rising and have little to do with future recurrence? Thanks!
Andrew112
in
Prostate Cancer Network
4 years ago
Growth hormone deficiency after head injury
He is having great difficulty finding an endo who will do this, although he had a serious head injury in his teens and research indicates that around a quarter of head injury survivors will suffer pituitary damage, and he has the symptoms of suicidal depression, anxiety, weight gain,
testosterone
deficiency
He is having great difficulty finding an endo who will do this, although he had a serious head injury in his teens and research indicates that around a quarter of head injury survivors will suffer pituitary damage, and he has the symptoms of suicidal depression, anxiety, weight gain,
testosterone
deficiency
headinjuryhypo
in
Headway
4 years ago
Can lowered testosterone reduce penis length?
However, I'm sure I've read that low
testosterone
can have night sweats as a side effect. If it does prove to be that, I do wonder if it could have anything to do with my penis length. I've the last couple of years, it has actually gone down from 7.2 erect, to 5.5.
However, I'm sure I've read that low
testosterone
can have night sweats as a side effect. If it does prove to be that, I do wonder if it could have anything to do with my penis length. I've the last couple of years, it has actually gone down from 7.2 erect, to 5.5.
NorthLeedsJohnny
in
Men's Health Forum (Penis Health)
4 years ago
Testosterone and PD
Has any male PwPD over 60 yrs old noticed any improvement or benefit in taking
testosterone
? It's bad enough having PD, but the loss of muscle mass, loss of drive, and gaining of weight associated with reduced
testosterone
is more than I can handle.
Has any male PwPD over 60 yrs old noticed any improvement or benefit in taking
testosterone
? It's bad enough having PD, but the loss of muscle mass, loss of drive, and gaining of weight associated with reduced
testosterone
is more than I can handle.
DeanGreen
in
Cure Parkinson's
4 years ago
Estradiol vs ADT?
of the hive mind on this: I hear and read occasionally about oestradiol as being equivalent to LHRH agonists for
testosterone
suppression minus some of the famous nasty side effects.
of the hive mind on this: I hear and read occasionally about oestradiol as being equivalent to LHRH agonists for
testosterone
suppression minus some of the famous nasty side effects.
London441
in
Advanced Prostate Cancer
4 years ago
PCOS
The results today has said that my
testosterone
levels are slightly high and that PCOS is a common problem that I could have.
The results today has said that my
testosterone
levels are slightly high and that PCOS is a common problem that I could have.
Babypink1
in
Endometriosis UK
4 years ago
New and confused about some hormone results
I guess I was expecting to see higher levels of
Testosterone
. Is there anything in the levels below that point to anything related to my fatigue/pain/brain fog? Do I even have PCOS anymore?
I guess I was expecting to see higher levels of
Testosterone
. Is there anything in the levels below that point to anything related to my fatigue/pain/brain fog? Do I even have PCOS anymore?
Columbo40
in
PCOS UK (Verity)
4 years ago
New results, pituitary and Paul Robinson
Since the start of my problems I’ve had issues with estrogen dominance and I suspect my
testosterone
is low too. Any doctor I’ve asked has brushed it off but it’s just too much of a coincidence and indeed I believe what happened to me was a perfect storm, agains term used in the book.
Since the start of my problems I’ve had issues with estrogen dominance and I suspect my
testosterone
is low too. Any doctor I’ve asked has brushed it off but it’s just too much of a coincidence and indeed I believe what happened to me was a perfect storm, agains term used in the book.
Murphysmum
in
Thyroid UK
4 years ago
This isn’t good news. Low T at high risk of death from Covid 19
https://www.google.com/amp/s/www.dailymail.co.uk/sciencetech/article-8312771/amp/Male-coronavirus-patients-low-
testosterone
-levels-likely-die-COVID-19.html
https://www.google.com/amp/s/www.dailymail.co.uk/sciencetech/article-8312771/amp/Male-coronavirus-patients-low-
testosterone
-levels-likely-die-COVID-19.html
Longterm101
in
Advanced Prostate Cancer
4 years ago
DHEA ? Yea or Nay
Just saw a video how DHEA is contributing to
testosterone
levels and how it can be out of balance when under stress. Also it was mentioned to NOT self prescribe. Tbh I do not know my ovarian reserve numbers so am wondering: 1: do you take DHEA, self prescribed or on doctors advice?
Just saw a video how DHEA is contributing to
testosterone
levels and how it can be out of balance when under stress. Also it was mentioned to NOT self prescribe. Tbh I do not know my ovarian reserve numbers so am wondering: 1: do you take DHEA, self prescribed or on doctors advice?
Hidden
in
Fertility Network UK
4 years ago
Not sure where to turn now...
TSH is at 2.8 T3 is at 4.5 Vit D/B12/Ferratin/Folate/
Testosterone
/Glucose - all within range. What is wrong with me? Am I just being a real wuss and need to accept this is how I'm going to feel forever more? I'm 35 and can't even climb the stairs without getting puffed out on a bad day.
TSH is at 2.8 T3 is at 4.5 Vit D/B12/Ferratin/Folate/
Testosterone
/Glucose - all within range. What is wrong with me? Am I just being a real wuss and need to accept this is how I'm going to feel forever more? I'm 35 and can't even climb the stairs without getting puffed out on a bad day.
sassytea
in
Thyroid UK
4 years ago
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