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Experiences with
Prostate-specific antigen (PSA)
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Lupron unjection not reducing PSA
I was then put on Orgovyx, that did not stop
psa
from rising. I was then put on monthly injections of lupron, the
psa
was 25. Lupron dropped the
psa
to 10. I have been on lupron for 4 monthly injections. My
PSA
keeps rising, last
psa
test was 28 last month, guess I'm castrate resistant now.
I was then put on Orgovyx, that did not stop
psa
from rising. I was then put on monthly injections of lupron, the
psa
was 25. Lupron dropped the
psa
to 10. I have been on lupron for 4 monthly injections. My
PSA
keeps rising, last
psa
test was 28 last month, guess I'm castrate resistant now.
woppaginny
in
Advanced Prostate Cancer
3 months ago
PSA rise
On Dec 6 my
PSA
was 0.04 then on March 19 it was 0.21 so this indicates a rise in Mets. Is this too low for a scan? What should be the next steps?
On Dec 6 my
PSA
was 0.04 then on March 19 it was 0.21 so this indicates a rise in Mets. Is this too low for a scan? What should be the next steps?
Howard53545
in
Advanced Prostate Cancer
2 months ago
new PSA
my
PSA
rose from .04 in Jan to now .21 so it’s moving up. I assume this is still too low for a scan to determine where pc is at. I was undetected for 2 years after radiation of pelvic area.
my
PSA
rose from .04 in Jan to now .21 so it’s moving up. I assume this is still too low for a scan to determine where pc is at. I was undetected for 2 years after radiation of pelvic area.
Howard53545
in
Advanced Prostate Cancer
2 months ago
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PSA increasing
My Dad’s
PSA
started increasing 2.5 years after diagnosis. It was 0.008 in December, 0.024 at the beginning of March and 0.029 on yesterday. Please advise. Any suggestions are greatly appreciated.
My Dad’s
PSA
started increasing 2.5 years after diagnosis. It was 0.008 in December, 0.024 at the beginning of March and 0.029 on yesterday. Please advise. Any suggestions are greatly appreciated.
Simonapo
in
Advanced Prostate Cancer
2 months ago
PSA rise due to physical activity
Can this explain the
PSA
rise ?
Can this explain the
PSA
rise ?
Ian99
in
Advanced Prostate Cancer
2 months ago
PSA monitoring
Dad had his 5 years appointment this week and he had surgical removal in 2018 and it was only 0.08 post surgery ( 4+3) and had 37 rounds of radiation and was undetectable for 2 years plus 6 mo the of Lupton. Since 2021, it has fluctuated from 0.05, 0.07, 0.09, 0.07, 0.12, 0.11, 0.09, 0.12 without any
Dad had his 5 years appointment this week and he had surgical removal in 2018 and it was only 0.08 post surgery ( 4+3) and had 37 rounds of radiation and was undetectable for 2 years plus 6 mo the of Lupton. Since 2021, it has fluctuated from 0.05, 0.07, 0.09, 0.07, 0.12, 0.11, 0.09, 0.12 without any
k538
in
Prostate Cancer Network
2 months ago
Rising psa
.: negative
PSA
: 29-01-2024: 0,86.
PSA
: 7 February 2024: 0,89.
.: negative
PSA
: 29-01-2024: 0,86.
PSA
: 7 February 2024: 0,89.
ezzeddine
in
Prostate Cancer Network
2 months ago
PSA REACHES 5,125 !!
Diagnosed seven years ago with metastatic prostate cancer (
PSA
1,666). Got down to 0.9 with hormone (eligard) shots.
PSA
increased, even with eligard. Recently completed my fourth of five Pluvicto infusion treatments (last due in one week). Currently, my
PSA
is at 5,125.
Diagnosed seven years ago with metastatic prostate cancer (
PSA
1,666). Got down to 0.9 with hormone (eligard) shots.
PSA
increased, even with eligard. Recently completed my fourth of five Pluvicto infusion treatments (last due in one week). Currently, my
PSA
is at 5,125.
fsiefert
in
Advanced Prostate Cancer
2 months ago
My PCa history
August 2014 start RT for prostate bed (40 sessions 35+5 busters for total of 72 Gy) September 2017
PSA
0.01 August 2018
PSA
0.02 June 2020
PSA
0.03 February 2022
PSA
0.7 March 2022
PSA
1.03, testosterone 115 (
PSA
doubling time 2.5 month).
August 2014 start RT for prostate bed (40 sessions 35+5 busters for total of 72 Gy) September 2017
PSA
0.01 August 2018
PSA
0.02 June 2020
PSA
0.03 February 2022
PSA
0.7 March 2022
PSA
1.03, testosterone 115 (
PSA
doubling time 2.5 month).
Maxi54
in
Advanced Prostate Cancer
7 days ago
Similar question to Ezzedine. PSA rising
PSA
was 0.9 (it turns out I have a non secreting prostate. I had 37 sessions of EBRT and 3 years zoladex. Whilst under ADT and for 1 year after ADT conclusion my
PSA
was 0.01 (indecipherable) Then a year ago my
PSA
was 0.02, then 0.03 and last week it was 0.13.
PSA
was 0.9 (it turns out I have a non secreting prostate. I had 37 sessions of EBRT and 3 years zoladex. Whilst under ADT and for 1 year after ADT conclusion my
PSA
was 0.01 (indecipherable) Then a year ago my
PSA
was 0.02, then 0.03 and last week it was 0.13.
arry4424
in
Prostate Cancer Network
2 months ago
PSA Bounce After Radiation Therapy
I am trying to understand
PSA
bounce or change in
PSA
levels after RT and have found two studies useful.
I am trying to understand
PSA
bounce or change in
PSA
levels after RT and have found two studies useful.
kainasar
in
Advanced Prostate Cancer
2 months ago
Rising PSA
I'm Poollover, Just got the results of a blood test and my
PSA
went up from 0.67 to 0.77. I'm on Orgovyx and Zytiga. I'm 86 years old. How concerned should I be? 8 months ago it was about 12. That was before medication. Also slightly anemic. What are my options? Terry
I'm Poollover, Just got the results of a blood test and my
PSA
went up from 0.67 to 0.77. I'm on Orgovyx and Zytiga. I'm 86 years old. How concerned should I be? 8 months ago it was about 12. That was before medication. Also slightly anemic. What are my options? Terry
Poollover
in
Advanced Prostate Cancer
3 months ago
Input on Timing of Initial ADT after RP/SRT Failed
PSA
0.36 ng/mL. Jul – Aug 2022 — 35 sessions of SRT to prostate bed only; 70 Gy. Nov 2022 —
PSA
0.05, mainly from effects of Eligard. Mar and May 2023 —
PSA
0.13 and 0.11 respectively. Oct and Dec 2023 —
PSA
0.33, 0.37, respectively.
PSA
0.36 ng/mL. Jul – Aug 2022 — 35 sessions of SRT to prostate bed only; 70 Gy. Nov 2022 —
PSA
0.05, mainly from effects of Eligard. Mar and May 2023 —
PSA
0.13 and 0.11 respectively. Oct and Dec 2023 —
PSA
0.33, 0.37, respectively.
dans_journey
in
Advanced Prostate Cancer
9 days ago
Failed RP & SRT; Negative PSMA PET
biochemical recurrence threshold at 0.21 ng/mL NOV 2021 - PSMA PET scan with
PSA
at 0.22 ng/mL; no signs of cancer MAY 2022 - Six-month dose of Eligard in advance of SRT;
PSA
at 0.36 ng/mL JUL-AUG 2022 - 35 sessions of IMRT to prostate bed only MAR 2023 -
PSA
0.13 ng/mL MAY 2023 -
PSA
0.11 ng/mL
biochemical recurrence threshold at 0.21 ng/mL NOV 2021 - PSMA PET scan with
PSA
at 0.22 ng/mL; no signs of cancer MAY 2022 - Six-month dose of Eligard in advance of SRT;
PSA
at 0.36 ng/mL JUL-AUG 2022 - 35 sessions of IMRT to prostate bed only MAR 2023 -
PSA
0.13 ng/mL MAY 2023 -
PSA
0.11 ng/mL
dans_journey
in
Advanced Prostate Cancer
3 months ago
Pluvicto still working well
So far: Aug 16:
PSA
99.7
Aug 21: Pluvicto
#1
Sep 11:
PSA
106
Sep 28:
PSA
91.8
Oct 05: Pluvicto
#2
Oct 25:
PSA
57.8
Nov 09:
PSA
47.4
Nov 16: Pluvicto
#3
Dec 06:
PSA
31.8
Dec 28:
PSA
26.5[/
So far: Aug 16:
PSA
99.7
Aug 21: Pluvicto
#1
Sep 11:
PSA
106
Sep 28:
PSA
91.8
Oct 05: Pluvicto
#2
Oct 25:
PSA
57.8
Nov 09:
PSA
47.4
Nov 16: Pluvicto
#3
Dec 06:
PSA
31.8
Dec 28:
PSA
26.5[/
Miccoman
in
Advanced Prostate Cancer
3 months ago
Treatment
The last three
PSA
readings (every three months) were 0.01 / 0.00 / 0.00, I expect
PSA
control soon. You can find more detailed information in my post. I hope for the best, and I wish you the same. Good luck
The last three
PSA
readings (every three months) were 0.01 / 0.00 / 0.00, I expect
PSA
control soon. You can find more detailed information in my post. I hope for the best, and I wish you the same. Good luck
adam1967adam
in
Advanced Prostate Cancer
1 month ago
If PSA is Suppressed by Doublet ADT, Will Salvage IMRT Cause a PSA Rise?
His radiation oncologist said it may take several months before the
psa
calms down, so he would like to see him in July. My question is that, since he is already undetectable due to Lupron/Abi/Pred, would the radiation treatment cause a
psa
rise despite being on the hormone therapy.?
His radiation oncologist said it may take several months before the
psa
calms down, so he would like to see him in July. My question is that, since he is already undetectable due to Lupron/Abi/Pred, would the radiation treatment cause a
psa
rise despite being on the hormone therapy.?
103532
in
Advanced Prostate Cancer
23 days ago
My own PSA values over time: 70% drop in just 3 months on Dutasteride and no ADT
Here are my own
PSA
values versus time plot. You can see there is an exponential rise in
PSA
starting at around 6/1/23, and doubling from
PSA
= 5 to 10 in about 8 months. My MRI at
PSA
= 10 showed a T3a tumor about 1.3 cm long (PIRADS 5).
Here are my own
PSA
values versus time plot. You can see there is an exponential rise in
PSA
starting at around 6/1/23, and doubling from
PSA
= 5 to 10 in about 8 months. My MRI at
PSA
= 10 showed a T3a tumor about 1.3 cm long (PIRADS 5).
janebob99
in
Prostate Cancer Network
2 months ago
Rising PSA
In one year
PSA
has been rising. Up to 14 now. Dr. Aggarwal says no longer treat
PSA
# only scan results. Yet, CT with contrast is not definitive. Thoughts? Thank you!
In one year
PSA
has been rising. Up to 14 now. Dr. Aggarwal says no longer treat
PSA
# only scan results. Yet, CT with contrast is not definitive. Thoughts? Thank you!
JolleySprings
in
Advanced Prostate Cancer
3 months ago
PSA uptick
His
PSA
has been at/near undetected (<0.01-0.02) for several years, but recently there has been an uptick to 0.08 (similar on a recheck, so not lab error). Obviously still low-level, but concerning signal. Other labs are stable and bone scan a few months ago was stable.
His
PSA
has been at/near undetected (<0.01-0.02) for several years, but recently there has been an uptick to 0.08 (similar on a recheck, so not lab error). Obviously still low-level, but concerning signal. Other labs are stable and bone scan a few months ago was stable.
mediocra
in
Advanced Prostate Cancer
3 months ago
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