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Provenge
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What's Next?
Ten years ago surgery, then IMRT, several years of Lupron/Bicalutamide,
Provenge
, Radium 233, Taxotere and currently Jevtana. I am Stage 4 with bone/lymph node mets. PSA rising after 4 infusions of Jevtana (180). Bone scan/CT update in two weeks. Lost 35#, but still vertical.
Ten years ago surgery, then IMRT, several years of Lupron/Bicalutamide,
Provenge
, Radium 233, Taxotere and currently Jevtana. I am Stage 4 with bone/lymph node mets. PSA rising after 4 infusions of Jevtana (180). Bone scan/CT update in two weeks. Lost 35#, but still vertical.
Shepard
in
Advanced Prostate Cancer
4 years ago
Synergy between radiation of metastases and immunotherapy confirmed
In a short-term phase 2 trial, Xofigo (radium 223 chloride) was combined with
Provenge
(sipuleucel-T) in castration-resistant patients.
In a short-term phase 2 trial, Xofigo (radium 223 chloride) was combined with
Provenge
(sipuleucel-T) in castration-resistant patients.
Tall_Allen
in
Advanced Prostate Cancer
4 years ago
Update and question
Will continue zytiga and 10mg prednisone. urologists wants me to start
provenge
. Oncologist said he wouldn't at this time. I'm leaning against it. Any comments on progress so far and suggestions? Also advice on taking or not taking
Provenge
?
Will continue zytiga and 10mg prednisone. urologists wants me to start
provenge
. Oncologist said he wouldn't at this time. I'm leaning against it. Any comments on progress so far and suggestions? Also advice on taking or not taking
Provenge
?
Altamonttt
in
Advanced Prostate Cancer
4 years ago
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1st dose of Lu177 PSMA Therapy at Fortis Memorial, Gurugram, India Complete and Looking Very Promising!
They create vaccines from an individuals cancer and as I understand their technology exceeds what we have in the US with
Provenge
. Take care everyone and thank you as always from all of your wisdom and support! Paige and Charlie
They create vaccines from an individuals cancer and as I understand their technology exceeds what we have in the US with
Provenge
. Take care everyone and thank you as always from all of your wisdom and support! Paige and Charlie
paige20180
in
Advanced Prostate Cancer
4 years ago
Xtandi to Zytiga
Prior to the Xtandi treatment my line of defense included the following: 06/2014 Elligard and Xgeva, following a determination that scans showed numerous metastatic deposits, APC determined. 06/2017 started
Provenge
treatment. .My profile showed all of this started with RP in 06/2006 and EBR in 02/
Prior to the Xtandi treatment my line of defense included the following: 06/2014 Elligard and Xgeva, following a determination that scans showed numerous metastatic deposits, APC determined. 06/2017 started
Provenge
treatment. .My profile showed all of this started with RP in 06/2006 and EBR in 02/
docbulldog
in
Advanced Prostate Cancer
4 years ago
Sipuleucel-T boosts survival versus abiraterone or enzalutamide alone in real-world mCRPC analysis
Real-world data showed that use of the immunotherapy sipuleucel-T (
Provenge
) during any line of treatment in men with metastatic castration-resistant prostate cancer (mCRPC) improved overall survival (OS) versus treatment regimens that included abiraterone acetate (Zytiga) or enzalutamide (Xtandi), but
Real-world data showed that use of the immunotherapy sipuleucel-T (
Provenge
) during any line of treatment in men with metastatic castration-resistant prostate cancer (mCRPC) improved overall survival (OS) versus treatment regimens that included abiraterone acetate (Zytiga) or enzalutamide (Xtandi), but
George71
in
Advanced Prostate Cancer
4 years ago
***Great monthly exam. ***
My course of treatment has been Zytiga, Prednisone,Eligard, Xgeva , and
Provenge
going on three years now. Doc says no need to see me again until October . Never give up never surrender. Leo
My course of treatment has been Zytiga, Prednisone,Eligard, Xgeva , and
Provenge
going on three years now. Doc says no need to see me again until October . Never give up never surrender. Leo
leo2634
in
Advanced Prostate Cancer
4 years ago
14 year journey
Next I did the immunotherapy treatment
Provenge
. Then I went on zytiga and xgeva. Next was the RA223 treatment. I was switch to Xtandi and firmigon and xgeva. My psa has been up to 44 and as low as .02. The last time it went above 40 I started the docetaxel chemotherapy.
Next I did the immunotherapy treatment
Provenge
. Then I went on zytiga and xgeva. Next was the RA223 treatment. I was switch to Xtandi and firmigon and xgeva. My psa has been up to 44 and as low as .02. The last time it went above 40 I started the docetaxel chemotherapy.
ZackD
in
Advanced Prostate Cancer
4 years ago
Treatment after chemo - PARP inhibitor or immunotherapy trial?
I had
Provenge
in 2016. I have discussed the next step with my MO at MD Anderson. One option is a PARP inhibitor.
I had
Provenge
in 2016. I have discussed the next step with my MO at MD Anderson. One option is a PARP inhibitor.
WhiteStrat
in
Advanced Prostate Cancer
4 years ago
Preparing for Provenge
Planning to add
Provenge
in several weeks after the radiation is concluded Any advice on steps I should take to mitigate the effects?
Planning to add
Provenge
in several weeks after the radiation is concluded Any advice on steps I should take to mitigate the effects?
Bigpike
in
Advanced Prostate Cancer
4 years ago
I've been thinking about my PCa and have some questions - would be glad for any thought or input
I did go through a course in Oct 2018 of
Provenge
- an immunotherapy - which he believed helped. I have had .005 and lower PSA for over the 2 years .
So my question: by using just an Oncologist - with excellent results - am I missing something by not going to a Urologist ?
I did go through a course in Oct 2018 of
Provenge
- an immunotherapy - which he believed helped. I have had .005 and lower PSA for over the 2 years .
So my question: by using just an Oncologist - with excellent results - am I missing something by not going to a Urologist ?
pjd55d
in
Prostate Cancer Network
4 years ago
Developments in the Continued Search for a Prostate Cancer Vaccine...
We have seen the development of
Provenge
which has proven useful for some and less so for others. The APCEDEN vaccine is being given in India and a gentleman on another forum had fantastic results with use of it over several years ( see posts by Fuzzman77 in Advanced Prostate Cancer ).
We have seen the development of
Provenge
which has proven useful for some and less so for others. The APCEDEN vaccine is being given in India and a gentleman on another forum had fantastic results with use of it over several years ( see posts by Fuzzman77 in Advanced Prostate Cancer ).
NPfisherman
in
Fight Prostate Cancer
4 years ago
Is stage 4 in a 57 year old more dangerous than in an older man?
My docs are hitting me with Lupron/Zytiga,
Provenge
, SBRT to the bone mets, Xgeva, and eventually Docetaxel and Xofigo.
My docs are hitting me with Lupron/Zytiga,
Provenge
, SBRT to the bone mets, Xgeva, and eventually Docetaxel and Xofigo.
V10fanatic
in
Advanced Prostate Cancer
4 years ago
Is biopsy good from 2 years ago?
He’s on Lupron has had chemo (dox) Zytiga,
Provenge
and Radiation to prostate. Zytiga worked for eight months .02 then started rising. We have asked repeatedly for gene sequencing. She keeps putting us off. We asked for
Provenge
but she said there was better things out there but never said what.
He’s on Lupron has had chemo (dox) Zytiga,
Provenge
and Radiation to prostate. Zytiga worked for eight months .02 then started rising. We have asked repeatedly for gene sequencing. She keeps putting us off. We asked for
Provenge
but she said there was better things out there but never said what.
Faith1111
in
Advanced Prostate Cancer
4 years ago
Confused about treatment options
So just asking is it unreasonable to ask about the
Provenge
as the next step. Thank you
So just asking is it unreasonable to ask about the
Provenge
as the next step. Thank you
Scootman
in
Advanced Prostate Cancer
4 years ago
I need help understanding enlarged lymph node
I was diagnosed in 2016 with gleason 9, had HIFU, external beam radiation, doxotel and
provenge
. I have had a tumor removed from out chest wall although the margins weren't clean and another one grew in the same spot along with a enlarged lymph node behind my collar bone.
I was diagnosed in 2016 with gleason 9, had HIFU, external beam radiation, doxotel and
provenge
. I have had a tumor removed from out chest wall although the margins weren't clean and another one grew in the same spot along with a enlarged lymph node behind my collar bone.
RayTrevitt
in
Advanced Prostate Cancer
4 years ago
My Luck Ran out
He also told that because my PSA is still so low, I am really not yet a candidate for
Provenge
. Obviously if my nest PSA reading is higher, I am sure that my next step will be bone scans, gnome sequencing etc. I would love to jump to Darolutamide vs.
He also told that because my PSA is still so low, I am really not yet a candidate for
Provenge
. Obviously if my nest PSA reading is higher, I am sure that my next step will be bone scans, gnome sequencing etc. I would love to jump to Darolutamide vs.
poofers
in
Advanced Prostate Cancer
4 years ago
Lu-177-PSMA-617 vs Jevtana (cabazitaxel): which should I do next?
.,
Provenge
, Checkpoint inhibitors)? • Will PARP inhibitors enhance the cell-kill rate? • Is PSA the best biomarker of effectiveness? • What are the best radionuclides to use (e.g., Ac-225, Th-227)? • What are the best/most specific ligands to use?
.,
Provenge
, Checkpoint inhibitors)? • Will PARP inhibitors enhance the cell-kill rate? • Is PSA the best biomarker of effectiveness? • What are the best radionuclides to use (e.g., Ac-225, Th-227)? • What are the best/most specific ligands to use?
Tall_Allen
in
Advanced Prostate Cancer
4 years ago
Input and opinions welcome
The plan (Duke) is to have a
Provenge
treatment now, get repeat bone scan and CT after that, then probably start on Daralutamide depending on scan results. Comments welcome. Hugh
The plan (Duke) is to have a
Provenge
treatment now, get repeat bone scan and CT after that, then probably start on Daralutamide depending on scan results. Comments welcome. Hugh
Blueslover
in
Advanced Prostate Cancer
4 years ago
In need of advise for my father
He has not had
Provenge
, Zytiga, Lu-177 (is only under trials here in the United States), Xofigo, Cytoxan, BAT (was informed my father has mutations that qualify him for testosterone trials).
He has not had
Provenge
, Zytiga, Lu-177 (is only under trials here in the United States), Xofigo, Cytoxan, BAT (was informed my father has mutations that qualify him for testosterone trials).
AerospaceElectrical
in
Advanced Prostate Cancer
4 years ago
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