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PSA no longer undetectable. Now what?
I had a
prostatectomy
in 2017, radiation, and nearly 3 years of Lupron, with the last injection on 5/10/20. Other details are in my profile. PSA was undetectable for 2.5 years. Yesterday's draw shows that it's 0.032.
I had a
prostatectomy
in 2017, radiation, and nearly 3 years of Lupron, with the last injection on 5/10/20. Other details are in my profile. PSA was undetectable for 2.5 years. Yesterday's draw shows that it's 0.032.
Istomin
in
Advanced Prostate Cancer
2 years ago
Low testosterone are associated with the extend of lymphnodal invasion at radical prostatectomy and extended pelvic lymph node dissection
Abstract Objective: To investigate clinical factors associated to lymphnodal metastasis load in patients who underwent to radical
prostatectomy
(RP) and extended pelvic lymph node dissection (ePLND).
Abstract Objective: To investigate clinical factors associated to lymphnodal metastasis load in patients who underwent to radical
prostatectomy
(RP) and extended pelvic lymph node dissection (ePLND).
Hidden
in
Advanced Prostate Cancer
2 years ago
RT/RP vs RT/ADT OCSS (overall cancer-specific survival)
Overall ten-year survival rates were 64 and 48 percent, respectively." b.https://www.mskcc.org/clinical-updates/
prostatectomy
-and-radiotherapy-combo-delivers-better-outcomes-advanced-prostate
Overall ten-year survival rates were 64 and 48 percent, respectively." b.https://www.mskcc.org/clinical-updates/
prostatectomy
-and-radiotherapy-combo-delivers-better-outcomes-advanced-prostate
Hidden
in
Advanced Prostate Cancer
2 years ago
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Early Salvage Radiation After RP Improves Outcomes in Relapsed Prostate Cancer
The time from
prostatectomy
to salvage RT did not affect these outcomes. Of the cohort, 133 (32.6%) patients received neoadjuvant or concurrent androgen deprivation therapy (ADT).
The time from
prostatectomy
to salvage RT did not affect these outcomes. Of the cohort, 133 (32.6%) patients received neoadjuvant or concurrent androgen deprivation therapy (ADT).
Graham49
in
Advanced Prostate Cancer
2 years ago
How does PCa affect Venous Thromboembolism risk?
The higher risk in the months after prostate cancer may reflect the higher risks of VTE associated with surgical interventions such as radical
prostatectomy
.
The higher risk in the months after prostate cancer may reflect the higher risks of VTE associated with surgical interventions such as radical
prostatectomy
.
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Can anyone shed some light on this subject?
He speculated that it may have been caused by my robotic
prostatectomy
. I started drinking some natural detox 'supplements', which have pretty much made my bowel movements normal. In addition to the normal bowel movements, I am finding that my incontinence issues have decreased significantly.
He speculated that it may have been caused by my robotic
prostatectomy
. I started drinking some natural detox 'supplements', which have pretty much made my bowel movements normal. In addition to the normal bowel movements, I am finding that my incontinence issues have decreased significantly.
E2-Guy
in
Advanced Prostate Cancer
2 years ago
Overcoming Drug Resistance in Advanced Prostate Cancer by Drug Repurposing
Evaluation of lymphovascular invasion as a prognostic predictor of overall survival after radical
prostatectomy
. Urol. Oncol. 2021;39:495.e1–495.e6. doi: 10.1016/j.urolonc.2021.01.007. - DOI - PubMed Harada M., Iida M., Yamaguchi M., Shida K.
Evaluation of lymphovascular invasion as a prognostic predictor of overall survival after radical
prostatectomy
. Urol. Oncol. 2021;39:495.e1–495.e6. doi: 10.1016/j.urolonc.2021.01.007. - DOI - PubMed Harada M., Iida M., Yamaguchi M., Shida K.
Scout4answers
in
Advanced Prostate Cancer
2 years ago
Re-Expression of ... AR in Receptor Negative Endocrine Cancers via GSK3 Inhibition. Lithium?
Of interest [4] - "Lithium Carbonate was administered to eight patients for four weeks prior to radical
prostatectomy
..." Anyone here using lithium? What kind & what dose? Looks like one should discuss with one's doctor before experimenting.
Of interest [4] - "Lithium Carbonate was administered to eight patients for four weeks prior to radical
prostatectomy
..." Anyone here using lithium? What kind & what dose? Looks like one should discuss with one's doctor before experimenting.
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Biochemical Recurrence: Radiation
He had hormone therapy shots for 3 months, then a
prostatectomy
in Feb. 2021. Now his PSA has risen to .4 so he was put on hormone therapy (Orgovyx) and they want to start radiation. It is called biochemical recurrence.
He had hormone therapy shots for 3 months, then a
prostatectomy
in Feb. 2021. Now his PSA has risen to .4 so he was put on hormone therapy (Orgovyx) and they want to start radiation. It is called biochemical recurrence.
EmilyParis
in
Prostate Cancer Network
2 years ago
Survival After Radical Prostatectomy vs Radiation Therapy in Clinical Node-Positive Prostate Cancer - Published in Advanced Prostate Cancer
This retrospective, observational study assessed the differences in clinical outcomes among patients with clinical node-positive (cN1) prostate cancer undergoing radiotherapy (RT) versus radical
prostatectomy
(RP).
This retrospective, observational study assessed the differences in clinical outcomes among patients with clinical node-positive (cN1) prostate cancer undergoing radiotherapy (RT) versus radical
prostatectomy
(RP).
JRPnSD
in
Advanced Prostate Cancer
2 years ago
Microbiomes of Urine and the Prostate Are Linked to Human Prostate Cancer Risk Groups
Prostate secretions (100–400 µl) were collected (from May 2017 to February 2020) via manual compression of the excised prostate <20 min after
prostatectomy
.
Prostate secretions (100–400 µl) were collected (from May 2017 to February 2020) via manual compression of the excised prostate <20 min after
prostatectomy
.
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Lycopene + Sulforaphane - Forms, Dosage, Upsides, Downsides?
Have Robotic
Prostatectomy
scheduled in a couple months. Done tons of research and the area I'm most "unsure" of is CAMs (Complimentary Alternative Medicines).
Have Robotic
Prostatectomy
scheduled in a couple months. Done tons of research and the area I'm most "unsure" of is CAMs (Complimentary Alternative Medicines).
jazj
in
Advanced Prostate Cancer
2 years ago
Overall survival (OS) & (MFS) in men with biochemical relapse (BCR) after radical prostatectomy / defer ADT treatment til metastatic
"ADT prior to mets may not improve QoL or OS in BCR prostate cancer and may result in irreversible adverse events at high costs. Early use of novel androgen receptor targeting drugs (NARTD) prolonged MFS in nonmetastatic-castration resistant prostate cancer (nmCRPC). However, clinical details prior
"ADT prior to mets may not improve QoL or OS in BCR prostate cancer and may result in irreversible adverse events at high costs. Early use of novel androgen receptor targeting drugs (NARTD) prolonged MFS in nonmetastatic-castration resistant prostate cancer (nmCRPC). However, clinical details prior
George71
in
Advanced Prostate Cancer
2 years ago
For those of you who had radiation, how did you manage nausea if you had it?
He didn't qualify for
prostatectomy
because it had spread beyond the capsule and into the nerve bundles and a few other areas nearby. He is a gleason 10, newly diagnosed.
He didn't qualify for
prostatectomy
because it had spread beyond the capsule and into the nerve bundles and a few other areas nearby. He is a gleason 10, newly diagnosed.
Radtech40
in
Advanced Prostate Cancer
2 years ago
Progesterone Receptor.
Using radical
prostatectomy
tissue, it was "found that a high density level of PGR in TE is an independent prognostic factor for progression to CF in PCa. Further, high PGR density levels are significant for progression to CF in patients with Gleason score ≥ 7."
Using radical
prostatectomy
tissue, it was "found that a high density level of PGR in TE is an independent prognostic factor for progression to CF in PCa. Further, high PGR density levels are significant for progression to CF in patients with Gleason score ≥ 7."
pjoshea13
in
Advanced Prostate Cancer
2 years ago
ART - BMC Urology: Comparison of various continence definitions in a large group of patients undergoing radical prostatectomy
I have constantly heard that 90% plus of men are "dry" at 1 year post RP...I have never believed this. Doctors report higher success for both continence and ED than actually occurs and there is little interest in standardizing the criteria used to measure the outcomes of surgery...in Germany this is
I have constantly heard that 90% plus of men are "dry" at 1 year post RP...I have never believed this. Doctors report higher success for both continence and ED than actually occurs and there is little interest in standardizing the criteria used to measure the outcomes of surgery...in Germany this is
RMontana
in
Active Surveillance - Prostate Cancer
2 years ago
Seeking Input on Salvage Radiation Therapy
I'm seeking input from those of you who may be AT LEAST TWO YEARS out from salvage radiation therapy (SRT) after a radical
prostatectomy
.
I'm seeking input from those of you who may be AT LEAST TWO YEARS out from salvage radiation therapy (SRT) after a radical
prostatectomy
.
dans_journey
in
Advanced Prostate Cancer
2 years ago
Next step. Some advise please
Prostatectomy
(Da Vinci) in february 2017. Recurrence in December 2019 (psa:0.21 ng/ml). PET/PSMA GA68 show the prostate bed and one lymph node were illuminated. 28 session of radiation was given (august 2020) to the prostate area (61 Gy) and the dose increased (63 Gy) to the PSMA uptake area.
Prostatectomy
(Da Vinci) in february 2017. Recurrence in December 2019 (psa:0.21 ng/ml). PET/PSMA GA68 show the prostate bed and one lymph node were illuminated. 28 session of radiation was given (august 2020) to the prostate area (61 Gy) and the dose increased (63 Gy) to the PSMA uptake area.
anpun
in
Advanced Prostate Cancer
2 years ago
Study suggesting pelvic lymph node dissection might be avoidable for some men with negative PSMA PET CT
Each patient’s preoperative PSMA PET/CT imaging results were compared against histology findings from extended PLND during radical
prostatectomy
.
Each patient’s preoperative PSMA PET/CT imaging results were compared against histology findings from extended PLND during radical
prostatectomy
.
Graham49
in
Advanced Prostate Cancer
2 years ago
Survival after Radical Prostatectomy versus Radiation Therapy in High-Risk and Very High-Risk Prostate Cancer
Soundbite: ""
[i][u]Our data suggest that radical
holds a cancer-specific mortality advantage over external beam radiotherapy in Johns Hopkins very high risk patients."
Soundbite: ""
[i][u]Our data suggest that radical
holds a cancer-specific mortality advantage over external beam radiotherapy in Johns Hopkins very high risk patients."
pjoshea13
in
Advanced Prostate Cancer
2 years ago
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