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Rising PSA last Lutetium 177 December 2022
My husband finished his 6th treatment of Lutetium 177, December 2022 PSA 1, PSA starting to rise May 4.6 September 8.4, the Oncologist can only offer Chemo, can refer him for R223 to another hospital, what are his choices now, chemo nearly killed him in 2010 Got COVID at Easter had 7 vaccinations,
My husband finished his 6th treatment of Lutetium 177, December 2022 PSA 1, PSA starting to rise May 4.6 September 8.4, the Oncologist can only offer Chemo, can refer him for R223 to another hospital, what are his choices now, chemo nearly killed him in 2010 Got COVID at Easter had 7 vaccinations,
Janhpr
in
Advanced Prostate Cancer
7 months ago
Latest Treatments for Advanced Prostate Cancer
I asked my computer (Bing) for the latest treatments for advanced prostate cancer. Response follows: [i]There are several treatments available for advanced prostate cancer, which is prostate cancer that has spread beyond the prostate to other parts of the body. The choice of treatment depends on many
I asked my computer (Bing) for the latest treatments for advanced prostate cancer. Response follows: [i]There are several treatments available for advanced prostate cancer, which is prostate cancer that has spread beyond the prostate to other parts of the body. The choice of treatment depends on many
NecessarilySo
in
Advanced Prostate Cancer
11 months ago
Declining psa #5
Gm ladies n gentlemen, after a stabilization psa between 1.5-1.7 for the last two months solely on ivermectin, I incorporated cbd, turmeric, zinc a lot of fruits especially cherries š and the pits (2-5 daily) of cherries, peaches, plums n apricots for the natural amygdalin nutrient and I am happy to
Gm ladies n gentlemen, after a stabilization psa between 1.5-1.7 for the last two months solely on ivermectin, I incorporated cbd, turmeric, zinc a lot of fruits especially cherries š and the pits (2-5 daily) of cherries, peaches, plums n apricots for the natural amygdalin nutrient and I am happy to
Nfler
in
Advanced Prostate Cancer
10 months ago
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Erleada - very unwell
Hi My husband was diagnosed about 9 years ago with PC 4+3 with possible Met to hip bone. Have been on Decapeptyl 6 months injections. Have had Xandi and now Erleada. Was on this for a year, but due to nausea, vomiting and awful taste in his mouth which affected his appetite and made diabetic control
Hi My husband was diagnosed about 9 years ago with PC 4+3 with possible Met to hip bone. Have been on Decapeptyl 6 months injections. Have had Xandi and now Erleada. Was on this for a year, but due to nausea, vomiting and awful taste in his mouth which affected his appetite and made diabetic control
Hidden
in
Advanced Prostate Cancer
7 months ago
Prostate Cancer (stage IV) identified in January and Small Cell Carcinoma (Neuro endocrine) in liver in August. Any suggestions?
In January, my dad was diagnosed with Prostate Cancer (Acinar Adenocarcinoma Prostate) stage 4, with PSA of 687. PCa had reached bones but not other major organs. He was put on Abiraterone and Degarelix. In August, PSA test showed that PSA had dropped to 2.7 and there was decrease in size and PSMA avidity
In January, my dad was diagnosed with Prostate Cancer (Acinar Adenocarcinoma Prostate) stage 4, with PSA of 687. PCa had reached bones but not other major organs. He was put on Abiraterone and Degarelix. In August, PSA test showed that PSA had dropped to 2.7 and there was decrease in size and PSMA avidity
RindaMan
in
Advanced Prostate Cancer
9 months ago
FYI: New data on progression of visceral mets without PSA progression (discordance) and ARAT/docetaxel therapy
Interesting study, folks. We know physical progression of PCa (i.e., new metastases) can occur without PSA progression. This is known as a discordance. But we don't know how often it occurs or why it occurs. In these instances, our greatest fear is "therapy-induced neuroendocrine prostate cancer
Interesting study, folks. We know physical progression of PCa (i.e., new metastases) can occur without PSA progression. This is known as a discordance. But we don't know how often it occurs or why it occurs. In these instances, our greatest fear is "therapy-induced neuroendocrine prostate cancer
SeosamhM
in
Advanced Prostate Cancer
10 months ago
Brain metastasis
New (Portuguese) anecdotal case study below. [1] When I began reading PCa studies on PubMed, I saw a lot of cell studies that used LNCaP (from a lymph PCa cell), PC3 (from a bone PCa cell) &/or DU145 (supposedly a brain met cell, but now described as "derived from a central nervous system metastasis
New (Portuguese) anecdotal case study below. [1] When I began reading PCa studies on PubMed, I saw a lot of cell studies that used LNCaP (from a lymph PCa cell), PC3 (from a bone PCa cell) &/or DU145 (supposedly a brain met cell, but now described as "derived from a central nervous system metastasis
pca2004
in
Fight Prostate Cancer
10 months ago
AUA 2023: PSA Response and Time-to-Castration Resistance Among Patients with mCSPCa Initiated on Apalutamide, Enzalutamide, or Abiraterone
The objective of this study was to describe a āreal-worldā experience of mCSPC patients treated with apalutamide, enzalutamide, and abiraterone acetate, with a focus on PSA response and development of castration resistance outcomes. This study identified patients with mCSPC newly initiated on apalutamide
The objective of this study was to describe a āreal-worldā experience of mCSPC patients treated with apalutamide, enzalutamide, and abiraterone acetate, with a focus on PSA response and development of castration resistance outcomes. This study identified patients with mCSPC newly initiated on apalutamide
skiingfiend
in
Advanced Prostate Cancer
10 months ago
PSMA Results
Iām five years Post surgery including removal of prostate & lymph nodes. Gleason 8 with Intraductal. Sepsis, DVT/PE after surgery which left me with chronic fatigue, brain fog and bad overactive bladder with incontinence. Four years post stereotactic radiotherapy to the left iliac area following a PSMA
Iām five years Post surgery including removal of prostate & lymph nodes. Gleason 8 with Intraductal. Sepsis, DVT/PE after surgery which left me with chronic fatigue, brain fog and bad overactive bladder with incontinence. Four years post stereotactic radiotherapy to the left iliac area following a PSMA
Bcgkelly
in
Prostate Cancer And Gay Men
7 months ago
PSMA RESULTS
Iām five years Post surgery including removal of prostate & lymph nodes. Gleason 8 with Intraductal. Sepsis, DVT/PE after surgery which left me with chronic fatigue, brain fog and bad overactive bladder with incontinence. Four years post stereotactic radiotherapy to the left iliac area following a PSMA
Iām five years Post surgery including removal of prostate & lymph nodes. Gleason 8 with Intraductal. Sepsis, DVT/PE after surgery which left me with chronic fatigue, brain fog and bad overactive bladder with incontinence. Four years post stereotactic radiotherapy to the left iliac area following a PSMA
Bcgkelly
in
Advanced Prostate Cancer
7 months ago
Senescent neutrophils and their subsequent impact on tumor progression and therapy resistance
I will comment after studying this for awhile, but it does open up an additional treatment path(s?) for PCa. (Excerpts) Calcinotto's team discovered that prostate tumor cells produce a molecule, ApoE, which can bind to and influence a type of immune cells, neutrophils, resulting in these cells acquiring
I will comment after studying this for awhile, but it does open up an additional treatment path(s?) for PCa. (Excerpts) Calcinotto's team discovered that prostate tumor cells produce a molecule, ApoE, which can bind to and influence a type of immune cells, neutrophils, resulting in these cells acquiring
cigafred
in
Fight Prostate Cancer
11 months ago
Here we go.......
FULL DISCLOSURE, LONG POST Had a TRUS biopsy end of September after AS of a rising PSA. Had a 3T MRI in November 2021 which showed a PIRADS 3 left base and PIRADS 2 right mid, prostate volume 40mL. 4K in August of this year was 57.1 with PSA of 7.8. DICIPHER from biopsy was .84. Clinical stage
FULL DISCLOSURE, LONG POST Had a TRUS biopsy end of September after AS of a rising PSA. Had a 3T MRI in November 2021 which showed a PIRADS 3 left base and PIRADS 2 right mid, prostate volume 40mL. 4K in August of this year was 57.1 with PSA of 7.8. DICIPHER from biopsy was .84. Clinical stage
ToolBeltZia
in
Prostate Cancer Network
7 months ago
Rapidly Rising PSA
As some of you know, I am now under the care of two excellent oncologists, including Prof. De Bono at Royal Marsden Cancer Centre. I was originally deemed to have a non-aggressive cancer (in 14 years my PSA has never exceeded 4.1) However, over the last 6 weeks (when I have been on no treatment whatsoever
As some of you know, I am now under the care of two excellent oncologists, including Prof. De Bono at Royal Marsden Cancer Centre. I was originally deemed to have a non-aggressive cancer (in 14 years my PSA has never exceeded 4.1) However, over the last 6 weeks (when I have been on no treatment whatsoever
CrocodileShoes
in
Advanced Prostate Cancer
10 months ago
PSA drop after ADT
My PSA went from 14.9 ug/l in May to 5.9 ug/l in June to 0.24 ug/l when tested 2 days ago after Lupron injection 3 months ago. Naturally I'm very relieved over the drop.My oncologist has pretty much left the decision to me on the ADT duration. I had earlier voiced my reservation about ADT on account
My PSA went from 14.9 ug/l in May to 5.9 ug/l in June to 0.24 ug/l when tested 2 days ago after Lupron injection 3 months ago. Naturally I'm very relieved over the drop.My oncologist has pretty much left the decision to me on the ADT duration. I had earlier voiced my reservation about ADT on account
John347
in
Advanced Prostate Cancer
10 months ago
Any ideas for hot flashes? Getting worse.
Dx in 8/2020 with Gleason 8. Had RP 11/2020. One lymph node involved so MO/RO at MGH recommended aggressive treatment. Went on Lupron and Abi for 2 years and 39 radiation treatments. All drug treatment ended in April of this year. Hot flashed started after a few months on Lupron and were bearable
Dx in 8/2020 with Gleason 8. Had RP 11/2020. One lymph node involved so MO/RO at MGH recommended aggressive treatment. Went on Lupron and Abi for 2 years and 39 radiation treatments. All drug treatment ended in April of this year. Hot flashed started after a few months on Lupron and were bearable
reichel
in
Advanced Prostate Cancer
11 months ago
PSA went from 0.97 to 0.99 during chemo treatments. Should we be concerned?
Hi all, My dad is currently going through chemo. History of his diagnosis is in my bio. He was diagnosed with stage 4 metastatic prostate cancer in March this year. We started triple therapy and just finished 4th dose of chemo. His latest blood results showed PSA of 0.99 however the ones 3 weeks before
Hi all, My dad is currently going through chemo. History of his diagnosis is in my bio. He was diagnosed with stage 4 metastatic prostate cancer in March this year. We started triple therapy and just finished 4th dose of chemo. His latest blood results showed PSA of 0.99 however the ones 3 weeks before
Jdhanoa
in
Advanced Prostate Cancer
10 months ago
RT without HT
I am approaching 78. My last PSA is 13,37. It was 1.4 in 2018 ie the last time I had a test. Prostate size 36 cc, prostate density 0.39. The MRI indicated a 14mm tumour fully contained within the prostate in the lower left quadrant, with āsomething on the right that I have been informed is possibly
I am approaching 78. My last PSA is 13,37. It was 1.4 in 2018 ie the last time I had a test. Prostate size 36 cc, prostate density 0.39. The MRI indicated a 14mm tumour fully contained within the prostate in the lower left quadrant, with āsomething on the right that I have been informed is possibly
Nordman
in
Prostate Cancer Network
7 months ago
PSA after salvage Brachy
an update for those that have asked questions about Salvage HDR Brachytherapy: Iām nearly 3 months out and had PSA test yesterday. Results were: 0.5. Using Abbott CMIA. This equals the nadir in 2014. Headed in right direction. Any questions please donāt hesitate to ask.
an update for those that have asked questions about Salvage HDR Brachytherapy: Iām nearly 3 months out and had PSA test yesterday. Results were: 0.5. Using Abbott CMIA. This equals the nadir in 2014. Headed in right direction. Any questions please donāt hesitate to ask.
Xcrunner1988
in
Prostate Cancer Network
7 months ago
dropped bicalutamide added Zytiga
lupron and bicalutamide for one month. PSA dropped 300/33 testosterone dropped 650/20. Then another month of treatment.(no PSA yet ) Five days ago stopped bicalutamide and added Zytiga. Sexual interest/function seems to have returned. Is this coincidence or an issue with meds?? Good news bad news
lupron and bicalutamide for one month. PSA dropped 300/33 testosterone dropped 650/20. Then another month of treatment.(no PSA yet ) Five days ago stopped bicalutamide and added Zytiga. Sexual interest/function seems to have returned. Is this coincidence or an issue with meds?? Good news bad news
pj1121
in
Advanced Prostate Cancer
9 months ago
PSA rise but scans are clear. Appetite and activity level are 0
I have spoken on here a few times about my dad who is on Erleada + ADT but it has failed. They have done quite a few scans recently because he is in significant pain. But all scans have come back āclearā in that there is no significant change in metastasis etc. we are at a point now where he barely
I have spoken on here a few times about my dad who is on Erleada + ADT but it has failed. They have done quite a few scans recently because he is in significant pain. But all scans have come back āclearā in that there is no significant change in metastasis etc. we are at a point now where he barely
StayingSTRNG
in
Advanced Prostate Cancer
11 months ago
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