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Transdermal estrogen/estradiol as monotherapy for Prostate Cancer
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Does anyone know of recent studies, clinical trials or Standard of Care (SoC) protocols using or studying estrogen gels, sprays, ointments or patches as hormone therapy for Prostate Cancer, particularly micrometastatic cancer that has not spread beyond the pelvic region? I am in discussions with my
Lost_Sheep
in
Prostate Cancer Network
4 months ago
CONTACT-02 Phase III: Cabozantinib-Atezolizumab combination works well in mCRPC with soft tissue metastasis
"The trial's rigorous methodology and the promising results, particularly in high-risk groups with liver metastasis, offer a beacon of hope for a patient population with limited treatment options. " "There was a 57% reduction in risk of progression or death in patients with liver metastasis with cabo
"The trial's rigorous methodology and the promising results, particularly in high-risk groups with liver metastasis, offer a beacon of hope for a patient population with limited treatment options. " "There was a 57% reduction in risk of progression or death in patients with liver metastasis with cabo
Maxone73
in
Advanced Prostate Cancer
4 months ago
Testosterone Recovery for 50% of Men
Here's an updated plot of Testosterone recovery time for 50% of men after stopping Lupron ADT, as a function of ADT duration. For ADT durations less than 20 months, the curve is basically linear with a slope = 1.0 (green line), meaning that the Recovery Time for 50% of men is roughly equal to the ADT
Here's an updated plot of Testosterone recovery time for 50% of men after stopping Lupron ADT, as a function of ADT duration. For ADT durations less than 20 months, the curve is basically linear with a slope = 1.0 (green line), meaning that the Recovery Time for 50% of men is roughly equal to the ADT
janebob99
in
Prostate Cancer Network
4 months ago
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A Phase 1, Open-Label, Multicenter Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer
I have a choice between this trial and a BAT trial. I’m already preferential to BAT, but without being too hasty, I wanted to see if anyone here has any experience with JANX00x before deciding.
I have a choice between this trial and a BAT trial. I’m already preferential to BAT, but without being too hasty, I wanted to see if anyone here has any experience with JANX00x before deciding.
No_stone_unturned
in
Advanced Prostate Cancer
4 months ago
Some Prostate Cancer Medical Practitioners on a Chart - 2024
Advanced Prostate Cancer Consensus Conference (APCCC) 2024
You decide if you think they're any good or not. ----- Previous title history, changed due to inaccuracies or controversies: 1. Worlds top Medical Oncologists -2024 2. Worlds top Prostate Cancer Medical Practioners - 2024 3. Some
Advanced Prostate Cancer Consensus Conference (APCCC) 2024
You decide if you think they're any good or not. ----- Previous title history, changed due to inaccuracies or controversies: 1. Worlds top Medical Oncologists -2024 2. Worlds top Prostate Cancer Medical Practioners - 2024 3. Some
skiingfiend
in
Advanced Prostate Cancer
4 months ago
Full body MRI?
We’ve been reading about full body MRIs and wonder if anyone has had one after radiation treatment for prostate cancer? Can this type of test pick up micro metastases? If the full body scan was “all clear” could ADT be shortened from 2 years to a lower amount?
We’ve been reading about full body MRIs and wonder if anyone has had one after radiation treatment for prostate cancer? Can this type of test pick up micro metastases? If the full body scan was “all clear” could ADT be shortened from 2 years to a lower amount?
Oatmeal2
in
Advanced Prostate Cancer
4 months ago
Prostate cancer made to my brain, skull and muscles in my head
Well, that’s something isn’t it? Have you ever seen that much cancer in someone’s head? Both my radiation oncologist and my and my regular oncologist at City of Hope said that this is something very unusual for prostate cancer to do. So there getting all of it for research to investigate what the
Well, that’s something isn’t it? Have you ever seen that much cancer in someone’s head? Both my radiation oncologist and my and my regular oncologist at City of Hope said that this is something very unusual for prostate cancer to do. So there getting all of it for research to investigate what the
Gl448
in
Advanced Prostate Cancer
4 months ago
CRS4PC and Zytiga side effects ?
My hubby is 69 and recently started Zytiga three weeks ago and it seems that he has developed moderate fatigue and low appetite since one week ago. I’m wondering if this could be a side effect of the Zytiga or if anyone thinks it’s an immunity infection attack.
My hubby is 69 and recently started Zytiga three weeks ago and it seems that he has developed moderate fatigue and low appetite since one week ago. I’m wondering if this could be a side effect of the Zytiga or if anyone thinks it’s an immunity infection attack.
Corgi16
in
Advanced Prostate Cancer
4 months ago
PSMA results
Here is the summary impression: IMPRESSION: * Prostate: PSMA (+) disease in the anterior mid- zone and apex of the prostate, consistent with primary malignancy. * Nodes: No tracer- avid pelvic, retroperitoneal, or mesenteric adenopathy * Distant metastases: No visceral or osseous metastatic
Here is the summary impression: IMPRESSION: * Prostate: PSMA (+) disease in the anterior mid- zone and apex of the prostate, consistent with primary malignancy. * Nodes: No tracer- avid pelvic, retroperitoneal, or mesenteric adenopathy * Distant metastases: No visceral or osseous metastatic
hwrjr
in
Prostate Cancer Network
4 months ago
Lengthened Cycles - is Prostap the cause of my longer cycles?
Hi ladies My first natural period returned in November. My December period was two days late and my January period was three days late. Did Prostap lengthen anyone else’s cycle? Xx
Hi ladies My first natural period returned in November. My December period was two days late and my January period was three days late. Did Prostap lengthen anyone else’s cycle? Xx
LadyM2019
in
Fertility Network UK
1 year ago
Exercise during meds (not stims)
Hi I had a prostap injection on Friday. And on my next cycle I'll be doing an ERA which will involve taking oestrogen and asprin and then progesterone when instructed. Are there any issues with exercising on this programme? I'd like to be able to do a short jog when I can and some strength training
Hi I had a prostap injection on Friday. And on my next cycle I'll be doing an ERA which will involve taking oestrogen and asprin and then progesterone when instructed. Are there any issues with exercising on this programme? I'd like to be able to do a short jog when I can and some strength training
Skittles11
in
Fertility Network UK
1 year ago
64Cu-SAR-bisPSMA Is Safe and Highly Effective in Detecting Tumours in Prostate Cancer Patients: results from COBRA trial
This could mean being way more precise in finding micro metastasis and in guided surgery! https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/149903-initial-cobra-results-clarity-s-sar-bispsma-is-safe-and-highly-effective-in-detecting-tumours-in-prostate-cancer-patients-phase
This could mean being way more precise in finding micro metastasis and in guided surgery! https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/149903-initial-cobra-results-clarity-s-sar-bispsma-is-safe-and-highly-effective-in-detecting-tumours-in-prostate-cancer-patients-phase
Maxone73
in
Advanced Prostate Cancer
4 months ago
Optilume, scans, and tests
I found an old post on this "Balloon" based BPH treatment but no replies. I had a cystoscopy today as part of my decision making process for BPH treatment first or Gleason 7 (4+3) treatment first. My urologist gave me a brochure for a procedure he does called Optilume from a company called Laborie.
I found an old post on this "Balloon" based BPH treatment but no replies. I had a cystoscopy today as part of my decision making process for BPH treatment first or Gleason 7 (4+3) treatment first. My urologist gave me a brochure for a procedure he does called Optilume from a company called Laborie.
SherpaT
in
Prostate Cancer Network
4 months ago
Not like a research from Johns Hopkins, but let's consider it
"Florida Atlantic University's Schmidt College of Medicine and collaborators are the first to demonstrate in vivo the chemo-preventive properties of alpha-santalol against prostate cancer development using a transgenic mouse model." https://www.news-medical.net/news/20240213/Study-demonstrates-chemo-preventive-properties-of-alpha-santalol-against-prostate-cancer-development.aspx
"Florida Atlantic University's Schmidt College of Medicine and collaborators are the first to demonstrate in vivo the chemo-preventive properties of alpha-santalol against prostate cancer development using a transgenic mouse model." https://www.news-medical.net/news/20240213/Study-demonstrates-chemo-preventive-properties-of-alpha-santalol-against-prostate-cancer-development.aspx
Maxone73
in
Fight Prostate Cancer
4 months ago
Heart Disease and Abiraterone/Zytiga
Hello Warriors My husband had a calcium score done and it shows atherosclerotic disease. Dr wants to increase statin dose but the Zytiga side effects are giving him increase joint pain and discomfort.We will see his cardiologist in April. Have any of you seen any increase in heart related issues( calcification
Hello Warriors My husband had a calcium score done and it shows atherosclerotic disease. Dr wants to increase statin dose but the Zytiga side effects are giving him increase joint pain and discomfort.We will see his cardiologist in April. Have any of you seen any increase in heart related issues( calcification
Keeper70
in
Advanced Prostate Cancer
4 months ago
Zytiga issue solved…
A big thank you to all who weighed in on whether I should take a lesser dose of abiraterone with food or just go without for a few days…….when I called my insurance company and got to talk to someone who gave a hoot it was discovered that a new pre-Auth was NOT needed…….10 or more phone calls later
A big thank you to all who weighed in on whether I should take a lesser dose of abiraterone with food or just go without for a few days…….when I called my insurance company and got to talk to someone who gave a hoot it was discovered that a new pre-Auth was NOT needed…….10 or more phone calls later
Tommyj2
in
Advanced Prostate Cancer
4 months ago
Keynote 365 Trial
Hey fellas, Seeing my MO tomorrow about enrolling in the Keynote 365 clinical trial with Keytruda in combination with another drug. Has anybody had any experience with Keytruda? Did it work for you? SE’s? I’m 17 years into this journey, castrate resistant, failed Xtandi, and recently failed Docetaxel
Hey fellas, Seeing my MO tomorrow about enrolling in the Keynote 365 clinical trial with Keytruda in combination with another drug. Has anybody had any experience with Keytruda? Did it work for you? SE’s? I’m 17 years into this journey, castrate resistant, failed Xtandi, and recently failed Docetaxel
deano58
in
Advanced Prostate Cancer
4 months ago
Diagnosed under 55
I’m looking specifically for men and partners of men who were diagnosed with de novo stage four prostate cancer at their initial diagnosis. The treatments are different and unfortunately so it the overall outlook. The younger men are diagnosed with PCa, the more aggressive the cancer tends to be.
I’m looking specifically for men and partners of men who were diagnosed with de novo stage four prostate cancer at their initial diagnosis. The treatments are different and unfortunately so it the overall outlook. The younger men are diagnosed with PCa, the more aggressive the cancer tends to be.
Vegasborn
in
Advanced Prostate Cancer
4 months ago
Found something that is helping so far!
I was diagnosed at age 35 with ADHD by my therapist who recognized the life patterns I had. My therapist disclosed they also have ADHD and recognized the same struggles they had dealt with when they were younger. I had two kids pretty close together in 2021 and 2022 and due to covid started working from
I was diagnosed at age 35 with ADHD by my therapist who recognized the life patterns I had. My therapist disclosed they also have ADHD and recognized the same struggles they had dealt with when they were younger. I had two kids pretty close together in 2021 and 2022 and due to covid started working from
BlessedNeuroDiverse
in
CHADD's Adult ADHD Support
1 year ago
Prostap periods
Hi, I started my second round of prostap injections last September as getting pregnant has been a fail for me. (My blog explains more about me so I won’t bore you with it again) Since having my last injection in November I haven’t had a period, however the first time I had had a period the following
Hi, I started my second round of prostap injections last September as getting pregnant has been a fail for me. (My blog explains more about me so I won’t bore you with it again) Since having my last injection in November I haven’t had a period, however the first time I had had a period the following
MarieC24
in
Fertility Network UK
1 year ago
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