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Abiraterone, Prednisone, Apalutamide combo Improves Prostate Cancer Outcomes, Leaves HRQoL Unaffected
Oncological outcomes improved with the addition of abiraterone acetate (Zytiga) plus prednisone (AAP) and apalutamide (Erleada) after radical prostatectomy and did not significantly affect health-related quality of life. https://www.targetedonc.com/view/abiraterone-prednisone-apalutamide-improves-prostate-cancer-outcomes-leaves-hrqol-unaffected
Oncological outcomes improved with the addition of abiraterone acetate (Zytiga) plus prednisone (AAP) and apalutamide (Erleada) after radical prostatectomy and did not significantly affect health-related quality of life. https://www.targetedonc.com/view/abiraterone-prednisone-apalutamide-improves-prostate-cancer-outcomes-leaves-hrqol-unaffected
Maxone73
in
Advanced Prostate Cancer
4 months ago
Thank god patients live longer, so we need new surrogate parameters to avoid slowing down research
As Patients Live Longer, New Criteria Needed for Prostate Cancer Trials https://news.feinberg.northwestern.edu/2024/01/25/as-patients-live-longer-new-criteria-needed-for-prostate-cancer-trials/
As Patients Live Longer, New Criteria Needed for Prostate Cancer Trials https://news.feinberg.northwestern.edu/2024/01/25/as-patients-live-longer-new-criteria-needed-for-prostate-cancer-trials/
Maxone73
in
Advanced Prostate Cancer
4 months ago
Firmagon vs Lupron
So, the question is what are the up or downs if switching from Firmagon to Lupron. I used Orgovyx until it didn't work, switched to Firmagon. Wanted either due to family history with heart issues. Dad, uncle's, brothers, all having issues. One brother recently having a major HA... But the convenience
So, the question is what are the up or downs if switching from Firmagon to Lupron. I used Orgovyx until it didn't work, switched to Firmagon. Wanted either due to family history with heart issues. Dad, uncle's, brothers, all having issues. One brother recently having a major HA... But the convenience
Cooolone
in
Advanced Prostate Cancer
4 months ago
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ASCO GU 2024 abstracts
This is the abstract for advanced prostate cancer: https://s3.amazonaws.com/files.oncologymeetings.org/prod/s3fs-public/2024-01/GU24-Prostate-Cancer-Advanced.pdf I suggest to use the search function in your browser, it's 235 pages of abstracts...
This is the abstract for advanced prostate cancer: https://s3.amazonaws.com/files.oncologymeetings.org/prod/s3fs-public/2024-01/GU24-Prostate-Cancer-Advanced.pdf I suggest to use the search function in your browser, it's 235 pages of abstracts...
Maxone73
in
Advanced Prostate Cancer
4 months ago
ASCO GU 2024 program
Ok! Here you go, but prostate cancer is only on day 1 https://conferences.asco.org/gu/program
Ok! Here you go, but prostate cancer is only on day 1 https://conferences.asco.org/gu/program
Maxone73
in
Advanced Prostate Cancer
4 months ago
A proposed metabolic treatment for prostate cancer, (theoretical only) using drugs approved for other conditions
See the PaSTe regimen below: pantoprozole (a drug currently used to reduce stomach acid), simvastatin (a statin used to reduce cholesterol), trimetazidine (a drug used to treat angina attacks). PaSTe. Blockade of the Lipid Phenotype of Prostate Cancer as Metabolic Therapy: A Theoretical Proposal
See the PaSTe regimen below: pantoprozole (a drug currently used to reduce stomach acid), simvastatin (a statin used to reduce cholesterol), trimetazidine (a drug used to treat angina attacks). PaSTe. Blockade of the Lipid Phenotype of Prostate Cancer as Metabolic Therapy: A Theoretical Proposal
Graham49
in
Advanced Prostate Cancer
4 months ago
Dicyclomine will work with Docetaxel ?
Will this work ? https://www.genengnews.com/topics/cancer/ibs-drug-restores-chemotherapy-effectiveness-against-resistant-prostate-cancer/
Will this work ? https://www.genengnews.com/topics/cancer/ibs-drug-restores-chemotherapy-effectiveness-against-resistant-prostate-cancer/
Manilo
in
Advanced Prostate Cancer
4 months ago
We could tell in advance if enzalutamide works on a patient: computational biology
hopefully it will be clinically tested soon ”For the study in Nature Communications, Mitrofanova's team developed computational algorithms to discover why the prostate cancer drug enzalutamide (sold under the brand name Xtandi) never works for some patients and why it eventually stops working in others
hopefully it will be clinically tested soon ”For the study in Nature Communications, Mitrofanova's team developed computational algorithms to discover why the prostate cancer drug enzalutamide (sold under the brand name Xtandi) never works for some patients and why it eventually stops working in others
Maxone73
in
Advanced Prostate Cancer
4 months ago
Abiraterone + Prednisone with Preexisting CAD
On November 1, 2023 a PET scan established that my metastatic prostate cancer is castrate resistance. I added Abiraterone + Prednisone to my 3 monthly Lupron shot. Same PET scan detected severe calcification in multiple coronary arteries, which was confirmed by heart CT scan and angiogram. I have severe
On November 1, 2023 a PET scan established that my metastatic prostate cancer is castrate resistance. I added Abiraterone + Prednisone to my 3 monthly Lupron shot. Same PET scan detected severe calcification in multiple coronary arteries, which was confirmed by heart CT scan and angiogram. I have severe
dac500
in
Advanced Prostate Cancer
4 months ago
Terms
Someone posted a glossary of the many acronyms related to prostate cancer. Where is it? Thanks.
Someone posted a glossary of the many acronyms related to prostate cancer. Where is it? Thanks.
Worked_the_World
in
Advanced Prostate Cancer
4 months ago
Is ADT routinely given after prostatectomy
Trying to decide between prostatectomy and radiation (I understand if there was recurrence, I would have to do radiation and ADT) Is surgery the best chance to avoid ADT altogether Also, can anyone recommended a Surgeon at MD Anderson I also have urinary symptoms due to an enlarged prostate, I
Trying to decide between prostatectomy and radiation (I understand if there was recurrence, I would have to do radiation and ADT) Is surgery the best chance to avoid ADT altogether Also, can anyone recommended a Surgeon at MD Anderson I also have urinary symptoms due to an enlarged prostate, I
Vortex12
in
Prostate Cancer Network
4 months ago
Keyhole surgery
Hi Guys, I haven’t had my periods it has been nearly a year due to taking prostap injection. However, my surgery was done in oct and my injections were stop. I want to try for a child but I can’t get pregnant due to not ovulating since I haven’t got my periods. Anyone else had the same experience.
Hi Guys, I haven’t had my periods it has been nearly a year due to taking prostap injection. However, my surgery was done in oct and my injections were stop. I want to try for a child but I can’t get pregnant due to not ovulating since I haven’t got my periods. Anyone else had the same experience.
FMohammed
in
Endometriosis UK
1 year ago
covid vaccine & prostate cancer
Any concerns/studies re covid vaccines bringing prostate cancer back? No politics just want to know if there are any reasons to be concerned.
Any concerns/studies re covid vaccines bringing prostate cancer back? No politics just want to know if there are any reasons to be concerned.
BL2023
in
Advanced Prostate Cancer
4 months ago
Google Research created an AI system that outperforms human doctors at diagnosing through conversation.
Google Research created an AI system that outperforms human doctors at diagnosing through conversation. https://blog.research.google/2024/01/amie-research-ai-system-for-diagnostic_12.html The Articulate Medical Intelligence Explorer (AMIE) is built on a Google LLM, and it's been optimized for "diagnostic
Google Research created an AI system that outperforms human doctors at diagnosing through conversation. https://blog.research.google/2024/01/amie-research-ai-system-for-diagnostic_12.html The Articulate Medical Intelligence Explorer (AMIE) is built on a Google LLM, and it's been optimized for "diagnostic
Darryl
Partner
in
Advanced Prostate Cancer
4 months ago
Hoilday
I started a Zytiga holiday yesterday. Still on Lupron for now. How long should I keep taking prednisone? I know Zytiga clears out pretty fast.
I started a Zytiga holiday yesterday. Still on Lupron for now. How long should I keep taking prednisone? I know Zytiga clears out pretty fast.
gsun
in
Advanced Prostate Cancer
4 months ago
Randomised clinical trial - prophylactic radiation therapy to asymptomatic bone metastases improved survival
Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial Authors: Erin F. Gillespie, MD, MPH https://orcid.org/0000-0002-1386-1542 gillespe@mskcc.org, Joanna C. Yang, MD, MPH, Noah J. Mathis, BA
Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial Authors: Erin F. Gillespie, MD, MPH https://orcid.org/0000-0002-1386-1542 gillespe@mskcc.org, Joanna C. Yang, MD, MPH, Noah J. Mathis, BA
Graham49
in
Advanced Prostate Cancer
4 months ago
Barry
Hi, Diagnosed with advanced prostate cancer stage 4 gleeson score 4+4, having six monthly degarelix injections, had bad side effects on second injection upset stomach diorea feeling very drained, wondering if 3 monthly injections would be better less chemical in system?
Hi, Diagnosed with advanced prostate cancer stage 4 gleeson score 4+4, having six monthly degarelix injections, had bad side effects on second injection upset stomach diorea feeling very drained, wondering if 3 monthly injections would be better less chemical in system?
littlemount
in
Advanced Prostate Cancer
4 months ago
Prostate cancer treatment and sexual mutilation
Well well. In the midst of the club no one wants to be a part of and just wanted to add my input. It seems that the treatment of prostate cancer often glazes over the fact that you will be sexually impacted severely. Depending on treatment outcome that could be a 0 to 7. Seems like the topic isn’t really
Well well. In the midst of the club no one wants to be a part of and just wanted to add my input. It seems that the treatment of prostate cancer often glazes over the fact that you will be sexually impacted severely. Depending on treatment outcome that could be a 0 to 7. Seems like the topic isn’t really
Yokohama2023
in
Advanced Prostate Cancer
4 months ago
News about phase 1 trial for mCRPC: BMS-986365
Plenty of hopefully good news at ASCO 2024 on the 25th of Jan "First disclosure of clinical outcomes from Phase 1 trial with BMS-986365 (CC-94676), the company’s first androgen receptor ligand-directed degrader in solid tumors from its targeted protein degradation platform, in metastatic castration-resistant
Plenty of hopefully good news at ASCO 2024 on the 25th of Jan "First disclosure of clinical outcomes from Phase 1 trial with BMS-986365 (CC-94676), the company’s first androgen receptor ligand-directed degrader in solid tumors from its targeted protein degradation platform, in metastatic castration-resistant
Maxone73
in
Advanced Prostate Cancer
4 months ago
Diet and Prostate Cancer
Many of us like myself know much about what is good or not good when it pertains to our diet. That said, I listened to this podcast from Dr. Geo . Figured I would share it. For me it was a good reminder and reinforcing to my diet practices. Hope you all find it helpfull. https://
Many of us like myself know much about what is good or not good when it pertains to our diet. That said, I listened to this podcast from Dr. Geo . Figured I would share it. For me it was a good reminder and reinforcing to my diet practices. Hope you all find it helpfull. https://
85745
in
Advanced Prostate Cancer
4 months ago
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