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đ§ŹUNC93B1 New genetic findings open up perspectives for future therapeutic approaches in Lupus
Hi lupis! đđŒ New study demonstrates a direct causal link between an overactive UNC93B1/TLR7 axis and lupus pathogenesis and indicates that blocking overactive TLR7 might be therapeutically effective. Their findings are expected to accelerate further development of TLR7 inhibitors for patients with
Hi lupis! đđŒ New study demonstrates a direct causal link between an overactive UNC93B1/TLR7 axis and lupus pathogenesis and indicates that blocking overactive TLR7 might be therapeutically effective. Their findings are expected to accelerate further development of TLR7 inhibitors for patients with
Naladog
in
LUPUS UK
5 months ago
Results
Hello I messaged on here recently about my symptoms and was recommended to take a private blood test, which I've done. So I'm surprised that they've all come back normal! I screenshot them but not all together. Think I need to now think it is actually not my thyroid, but rheumatoid after all!
Hello I messaged on here recently about my symptoms and was recommended to take a private blood test, which I've done. So I'm surprised that they've all come back normal! I screenshot them but not all together. Think I need to now think it is actually not my thyroid, but rheumatoid after all!
Flo2021
in
Thyroid UK
5 months ago
Hashimoto advice please
hello, I have had an underactive thyroid and been on Levothyroxine 75mg since 2015. Last November I had a private blood test done as I had been struggling with lots of âsymptomsâ and wondered if my thyroid could be the cause and it showed I have Hashimotoâs disease which I understand is an autoimmune
hello, I have had an underactive thyroid and been on Levothyroxine 75mg since 2015. Last November I had a private blood test done as I had been struggling with lots of âsymptomsâ and wondered if my thyroid could be the cause and it showed I have Hashimotoâs disease which I understand is an autoimmune
Philly2748
in
Thyroid UK
5 months ago
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niacin as cause of strokes and heart attacks?
I know a lot of us taking B Complex so posting this article to hear your thoughts. I take one from cytoplasm where itâs 16mg, I wonder if this is ok đ€ https://www.newscientist.com/article/2417665-niacin-supplements-linked-to-greater-risk-of-heart-attacks-and-strokes/ [ Link edited to remove potentially
I know a lot of us taking B Complex so posting this article to hear your thoughts. I take one from cytoplasm where itâs 16mg, I wonder if this is ok đ€ https://www.newscientist.com/article/2417665-niacin-supplements-linked-to-greater-risk-of-heart-attacks-and-strokes/ [ Link edited to remove potentially
Kari55
in
Thyroid UK
4 months ago
Wheat Diet may Exacerbate Multiple Sclerosis Severity
Wheat diet may exacerbate multiple sclerosis severity, research finds - Jan 2024
by Natkritta HĂŒppe, UniversitĂ€tsmedizin der Johannes Gutenberg-UniversitĂ€t Mainz https://medicalxpress.com/news/2024-01-wheat-diet-exacerbate-multiple-sclerosis.html
Highlights:
A research team at the University
Wheat diet may exacerbate multiple sclerosis severity, research finds - Jan 2024
by Natkritta HĂŒppe, UniversitĂ€tsmedizin der Johannes Gutenberg-UniversitĂ€t Mainz https://medicalxpress.com/news/2024-01-wheat-diet-exacerbate-multiple-sclerosis.html
Highlights:
A research team at the University
Bolt_Upright
in
Cure Parkinson's
5 months ago
My brother has advanced Prostate Cancer
I'm here for my brother. He is 55 now. He has diagnosed when he was 54 with advanced prostate cancer that had metastasized to his pelvic bone. He started hormone therapy on October 2022 and then started chemotherapy for 6 sessions from November 2022 till March 2023 and started Nubeqa at the same time
I'm here for my brother. He is 55 now. He has diagnosed when he was 54 with advanced prostate cancer that had metastasized to his pelvic bone. He started hormone therapy on October 2022 and then started chemotherapy for 6 sessions from November 2022 till March 2023 and started Nubeqa at the same time
rasher1
in
Advanced Prostate Cancer
7 months ago
Dr. Jones' Knowledge
Several times a week I want to share some of Dr. Jones' statements regarding PBC These are all taken from his book [u][i]The Definitive Guide for Patients Who Have Primary Biliary Cholangitis. I [/i][/u]think it's important to share some of the basics of this complicated disease. If you have any questions
Several times a week I want to share some of Dr. Jones' statements regarding PBC These are all taken from his book [u][i]The Definitive Guide for Patients Who Have Primary Biliary Cholangitis. I [/i][/u]think it's important to share some of the basics of this complicated disease. If you have any questions
DonnaBoll
Administrator
in
PBC Foundation
13 days ago
"High levels of niacin linked to heart disease, new research suggests"
"High levels of niacin, an essential B vitamin, may raise the risk of heart disease by triggering inflammation and damaging blood vessels, according to new research. The report, published Monday in Nature Medicine, revealed a previously unknown risk from excessive amounts of the vitamin ..." https:/
"High levels of niacin, an essential B vitamin, may raise the risk of heart disease by triggering inflammation and damaging blood vessels, according to new research. The report, published Monday in Nature Medicine, revealed a previously unknown risk from excessive amounts of the vitamin ..." https:/
JackBruce2024
in
Cure Parkinson's
4 months ago
Starting Abiraterone and predniSONE
Tomorrow morning I take my first dose of Abiraterone (Zytiga) and predniSONE for metastatic castrate resistant prostate cancer. I don't know what kind of side effects I would get. I hope I would tolerate the treatment well. Reaching this stage of my cancer I reflect on my 12 year journey with prostate
Tomorrow morning I take my first dose of Abiraterone (Zytiga) and predniSONE for metastatic castrate resistant prostate cancer. I don't know what kind of side effects I would get. I hope I would tolerate the treatment well. Reaching this stage of my cancer I reflect on my 12 year journey with prostate
dac500
in
Advanced Prostate Cancer
7 months ago
PAS blog - Dr Chandy
Hi All, Just posting this in case not posted already. https://pernicious-anaemia-society.org/pernicious-anaemia/dr-joseph-chandy-kayyalackom-a-reflection/
Hi All, Just posting this in case not posted already. https://pernicious-anaemia-society.org/pernicious-anaemia/dr-joseph-chandy-kayyalackom-a-reflection/
Sleepybunny
in
Pernicious Anaemia Society
5 months ago
Drop in resting heart rate since pred
HiI have been on 40mg pred for suspected GCA for2 weeks now. ( actually was 60 in first week then dropped to 40 in second). I had a temporal artery biopsy yesterday so resting up and taking it easy. I wear a fitbit so am aware of my usual resting heart rate. It is normally between 61-65. When asleep
HiI have been on 40mg pred for suspected GCA for2 weeks now. ( actually was 60 in first week then dropped to 40 in second). I had a temporal artery biopsy yesterday so resting up and taking it easy. I wear a fitbit so am aware of my usual resting heart rate. It is normally between 61-65. When asleep
kalgoorlie
in
PMRGCAuk
4 months ago
Legal Advice?
Hi All, Although this post is not MS-related, I wanted to reach out to my MSAA Community for their input. Perhaps someone here can point me in the right direction, as I don't really have the money to hire an attorney. Unfortunately, this situation doesn't lend itself to any "free advice and/or attorneys
Hi All, Although this post is not MS-related, I wanted to reach out to my MSAA Community for their input. Perhaps someone here can point me in the right direction, as I don't really have the money to hire an attorney. Unfortunately, this situation doesn't lend itself to any "free advice and/or attorneys
DM0329
in
My MSAA Community
7 months ago
Research Lounge FREE Online Event: Does knowledge of liver scarring affect drinking behaviour?
Does knowing the effects of alcohol on your liver change your drinking?
Researchers have been looking at how people's drinking behaviours may change when they know that alcohol is damaging their liver. They have some interesting and thought-provoking results to share with you on:
Wednesday
Does knowing the effects of alcohol on your liver change your drinking?
Researchers have been looking at how people's drinking behaviours may change when they know that alcohol is damaging their liver. They have some interesting and thought-provoking results to share with you on:
Wednesday
BritishLiverTrust1
Partner
in
British Liver Trust
7 months ago
Multiple mechanisms to clear a-synuclein with natural substances (in mice).
 For informational purposes only Alpha Synuclein  1.   INTRODUCTION:  There are no effective treatments nor drugs available to modify disease progression
 For informational purposes only Alpha Synuclein  1.   INTRODUCTION:  There are no effective treatments nor drugs available to modify disease progression
House2
in
Cure Parkinson's
7 months ago
Scientists have discovered a new cause of Parkinsons disease
https://scitechdaily.com/scientists-have-discovered-a-new-cause-of-parkinsons-disease/ A major discovery sheds light on the underlying mechanisms of Parkinsonâs disease, opening the door for novel therapeutic approaches down the line. Until recently, our understanding of Parkinsonâs disease has been
https://scitechdaily.com/scientists-have-discovered-a-new-cause-of-parkinsons-disease/ A major discovery sheds light on the underlying mechanisms of Parkinsonâs disease, opening the door for novel therapeutic approaches down the line. Until recently, our understanding of Parkinsonâs disease has been
NextStage
in
Cure Parkinson's
7 months ago
Heavy legs and low energy feeling
My recent thyroid results showed a below range T3, and I have been having trouble with a brand of thyroxine and feeling generally unwell as previously posted with some helpful advice. But, I have a feeling of heavy legs and low energy and wondered whether when the T3 is low it can cause this? I am
My recent thyroid results showed a below range T3, and I have been having trouble with a brand of thyroxine and feeling generally unwell as previously posted with some helpful advice. But, I have a feeling of heavy legs and low energy and wondered whether when the T3 is low it can cause this? I am
Sailing14
in
Thyroid UK
7 months ago
UK alternates to Flecainide?
Background is I had 2 ablations in 2019 but Afib started coming back in 2021 so I was put onto flecainide and bisoprolol. The flec ended up causing more issues but since stopping flecainide and staying on bisoprolol I've been doing pretty well. I was on a very low does of 1.25mg daily, I had an occasional
Background is I had 2 ablations in 2019 but Afib started coming back in 2021 so I was put onto flecainide and bisoprolol. The flec ended up causing more issues but since stopping flecainide and staying on bisoprolol I've been doing pretty well. I was on a very low does of 1.25mg daily, I had an occasional
kitenski
in
AF Association
4 months ago
Do you live with advanced liver disease? Are you interested in attending an in-person workshop in Bristol or Liverpool this month?
The British Liver Trust are working with UK CLIF, a dynamic new network of clinicians, patients, carers/relatives and researchers coming together over our shared interest to improve research and clinical outcomes for people with chronic liver failure. Cases of liver disease are rising alarmingly and
The British Liver Trust are working with UK CLIF, a dynamic new network of clinicians, patients, carers/relatives and researchers coming together over our shared interest to improve research and clinical outcomes for people with chronic liver failure. Cases of liver disease are rising alarmingly and
BritishLiverTrust1
Partner
in
British Liver Trust
7 months ago
Flecainide PIP info please
Diagnosed first episode March 2023 after exercising with shingles( unknowingly)- had four episodes since waking in AF, (also had Gastric probs during this time) Cardioverted back each time. Currently on Ablation list and awaiting tests to see if I can take Flecainide PIP, intolerant to Beta, Blockers
Diagnosed first episode March 2023 after exercising with shingles( unknowingly)- had four episodes since waking in AF, (also had Gastric probs during this time) Cardioverted back each time. Currently on Ablation list and awaiting tests to see if I can take Flecainide PIP, intolerant to Beta, Blockers
sunlovah
in
Atrial Fibrillation Support
4 months ago
Patient Day coming to Baltimore, Saturday March 02
Do not miss out on a unique opportunity to meet local medical experts to find out more about your heart health and in particular, heart rhythm conditions, such as atrial fibrillation. You will also have the chance to meet others living with these conditions. Breakfast, lunch, and a chance to speak
Do not miss out on a unique opportunity to meet local medical experts to find out more about your heart health and in particular, heart rhythm conditions, such as atrial fibrillation. You will also have the chance to meet others living with these conditions. Breakfast, lunch, and a chance to speak
TracyAdmin
Partner
in
AF Association
4 months ago
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