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Olaparib
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Olaparib Tolerability and the Management of Common Adverse Events in Patients With mCRPC
Pneumonitis was reported in 2% and 1.5% of patients in the
olaparib
and control groups, respectively, and one patient (0.4%) in the
olaparib
group experienced an event of MDS/AML after a 30-day follow-up period. Venous thromboembolic events occurred in 8% of
olaparib
and 3% of control patients.
Pneumonitis was reported in 2% and 1.5% of patients in the
olaparib
and control groups, respectively, and one patient (0.4%) in the
olaparib
group experienced an event of MDS/AML after a 30-day follow-up period. Venous thromboembolic events occurred in 8% of
olaparib
and 3% of control patients.
Balsam01
in
Advanced Prostate Cancer
2 years ago
Olaparib and food
I know the instructions say you can take
Olaparib
with or without food, however I have found that if I don’t take it with food or have food within at least half an hour, I start to heave and have to take a metoclopramide.
I know the instructions say you can take
Olaparib
with or without food, however I have found that if I don’t take it with food or have food within at least half an hour, I start to heave and have to take a metoclopramide.
Guilane
in
My Ovacome
2 years ago
Olaparib?
Has anyone taken “
olaparib
” as a treatment? If so, how well was it tolerated? Thank you!
Has anyone taken “
olaparib
” as a treatment? If so, how well was it tolerated? Thank you!
JolleySprings
in
Advanced Prostate Cancer
2 years ago
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Switching Olaparib to Niraparib first line
Hi there lovely people, I would really appreciate your input regarding Niraparib as a first line maintenance treatment after stopping
Olaparib
because of side effects.
Hi there lovely people, I would really appreciate your input regarding Niraparib as a first line maintenance treatment after stopping
Olaparib
because of side effects.
AnaJim
in
My Ovacome
2 years ago
Stage 3b 15 years !
I am currently on maintenance drug (
Olaparib
, 8 years 10 months) with a CA125 holding at below 3. This time round I have been NED 9 years and 2 months. Here’s to the next 15 years !
I am currently on maintenance drug (
Olaparib
, 8 years 10 months) with a CA125 holding at below 3. This time round I have been NED 9 years and 2 months. Here’s to the next 15 years !
Katmal-UK
in
My Ovacome
2 years ago
Olaparib dose reduction
I've been on
Olaparib
and Avastin for 2 weeks following frontline chemo for OC and already I've been told to stop because my white blood cells are way too low. I was on 600mg
Olaparib
and the nurse said to have a break and then if bloods improve to start again on a lower dose.
I've been on
Olaparib
and Avastin for 2 weeks following frontline chemo for OC and already I've been told to stop because my white blood cells are way too low. I was on 600mg
Olaparib
and the nurse said to have a break and then if bloods improve to start again on a lower dose.
Carpediem68
in
My Ovacome
2 years ago
My mother's good news!
. ❤️ She was diagnosed with OC Stage 4A in Dec, 2019 followed by surgery, pleural effusion draining, 6 rounds of chemo and on
Olaparib
since then (you can read her full story on my profile). Stay strong and remember there are many positive stories here! I wish you all the best, Milena
. ❤️ She was diagnosed with OC Stage 4A in Dec, 2019 followed by surgery, pleural effusion draining, 6 rounds of chemo and on
Olaparib
since then (you can read her full story on my profile). Stay strong and remember there are many positive stories here! I wish you all the best, Milena
Uniquem
in
My Ovacome
2 years ago
physical power loss
my father received the 2nd lutetium treatment, brain metastasis occurred, then we started cabataxel he also has a lot of muscle and appetite loss because he has COPD, he has difficulty walking ,also he has difficulty chewing Although his msi and brca tests are negative,can he still use keytruda or
olaparib
my father received the 2nd lutetium treatment, brain metastasis occurred, then we started cabataxel he also has a lot of muscle and appetite loss because he has COPD, he has difficulty walking ,also he has difficulty chewing Although his msi and brca tests are negative,can he still use keytruda or
olaparib
Perfetto-Zeynep
in
Advanced Prostate Cancer
2 years ago
Not able to tolerate olaparib, anyone?
Dear Lovelies, I have now developed severe low haemoglobin twice in the 4 months I have been on
olaparib
- four blood transfusions in total and am off
olaparib
for the second time. I am BRCa 2 , so really had great hopes as Brca2’s tend to respond well on this drug, cancerwise. .
Dear Lovelies, I have now developed severe low haemoglobin twice in the 4 months I have been on
olaparib
- four blood transfusions in total and am off
olaparib
for the second time. I am BRCa 2 , so really had great hopes as Brca2’s tend to respond well on this drug, cancerwise. .
Trickysite
in
My Ovacome
2 years ago
Here we go again probably!
I’ve been on
Olaparib
for 2 years but my ca125 has suddenly gone up to 50 last month and 92 this month. Feeling gutted and will be getting a scan. I suppose I just want to know how many have had remission again after a 2nd recurrence?
I’ve been on
Olaparib
for 2 years but my ca125 has suddenly gone up to 50 last month and 92 this month. Feeling gutted and will be getting a scan. I suppose I just want to know how many have had remission again after a 2nd recurrence?
MH500
in
My Ovacome
2 years ago
Olaparib & private healthcare
Has anyone managed to get their private healthcare provider to fund
Olaparib
the PARP inhibitor? (Or any others?) We’ve always had BUPA cover through hubby’s work but his new job doesn’t give it.
Has anyone managed to get their private healthcare provider to fund
Olaparib
the PARP inhibitor? (Or any others?) We’ve always had BUPA cover through hubby’s work but his new job doesn’t give it.
Emsymits
in
My Ovacome
2 years ago
Blue Sky News - Prostate Cancer Foundation of Australia - April 2023
Facing the Genetic Tiger: Expanding Access to gene Testing for Prostate Cancer
Since April 2022 AstraZeneca’s Lynparza (
Olaparib
) has been listed for eligible men with prostate cancer, responding to a length advocacy campaign by PCFA and others.
Facing the Genetic Tiger: Expanding Access to gene Testing for Prostate Cancer
Since April 2022 AstraZeneca’s Lynparza (
Olaparib
) has been listed for eligible men with prostate cancer, responding to a length advocacy campaign by PCFA and others.
marnieg46
in
Fight Prostate Cancer
1 year ago
Treatment Options at 2nd recurrence.
I was NED in December and went on
Olaparib
in January but my scan in May showed that it wasn't working. I have also been told that surgery is not an option now.
I was NED in December and went on
Olaparib
in January but my scan in May showed that it wasn't working. I have also been told that surgery is not an option now.
Meridian14
in
My Ovacome
2 years ago
Options
Well, I’ve had one year now with chemo and I’m on maintenance of Avastin and
Olaparib
. Should I have insisted on surgery? Does anyone without surgery survive for any length of time? I would be very grateful to hear from you lovely ladies. X
Well, I’ve had one year now with chemo and I’m on maintenance of Avastin and
Olaparib
. Should I have insisted on surgery? Does anyone without surgery survive for any length of time? I would be very grateful to hear from you lovely ladies. X
Guilane
in
My Ovacome
2 years ago
PARP inhibitors on NHS
- After first OC I believe now
Olaparib
is offered (sadly I’m ‘too long’ post chemo to qualify 🙄) Is it available for 2 years only? After first occurrence- Rucaparib? Or is it Niraparib? Is so, for how long? After second recurrence-
Olaparib
? Again for how long?
- After first OC I believe now
Olaparib
is offered (sadly I’m ‘too long’ post chemo to qualify 🙄) Is it available for 2 years only? After first occurrence- Rucaparib? Or is it Niraparib? Is so, for how long? After second recurrence-
Olaparib
? Again for how long?
Emsymits
in
My Ovacome
2 years ago
'Substandard' Control Arms in Clinical Trials– Practice found common in prostate cancer studies
Patients in the experimental arm received a poly (ADP-ribose) polymerase inhibitor,
olaparib
, and patients in the standard-of-care arm received a physician's choice treatment.
Patients in the experimental arm received a poly (ADP-ribose) polymerase inhibitor,
olaparib
, and patients in the standard-of-care arm received a physician's choice treatment.
GeorgeGlass
in
Advanced Prostate Cancer
2 years ago
Olaparib and Avastin
Last month, a few days after the avastin and
olaparib
, I had a weekend of terrible headaches, stomach ache and vomitting. On the Monday I rang the hospital and they advised me to come in. Typical .. I wasnt sick once while there, it was as if it had cleared up that day.
Last month, a few days after the avastin and
olaparib
, I had a weekend of terrible headaches, stomach ache and vomitting. On the Monday I rang the hospital and they advised me to come in. Typical .. I wasnt sick once while there, it was as if it had cleared up that day.
Mirrorplace
in
My Ovacome
2 years ago
Is anybody taking Olaparib for prostate cancer ?
Just found a scientific post that identifies the above drug can help feed cancer - is this old news ? Kindest Raoul
Just found a scientific post that identifies the above drug can help feed cancer - is this old news ? Kindest Raoul
raoulmaher
in
Advanced Prostate Cancer
2 years ago
Icon9
Olaparib
and cediranid thanks
Olaparib
and cediranid thanks
volleyp
in
My Ovacome
2 years ago
Olaparib (Lynparza) on its own or with Avastin for maintenance?
I am BRCA1 and have been told by my consultant that I can have
Olaparib
(Lynparza) on its own or with Avastin too. She is thinking that maybe
Olaparib
on its own may be the best option to reduce side effects but she said the decision is mine.
I am BRCA1 and have been told by my consultant that I can have
Olaparib
(Lynparza) on its own or with Avastin too. She is thinking that maybe
Olaparib
on its own may be the best option to reduce side effects but she said the decision is mine.
Carpediem68
in
My Ovacome
2 years ago
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