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TAPUR study
Following up on a genomics report (47 pages ! Plus 54 min consult) and came across this study (phase 2 basket trial) in the US. Essentially when exhausting, or before, standard of care options, allows patients to trial off label approved drugs using genomics to identify specific targetable variations
Following up on a genomics report (47 pages ! Plus 54 min consult) and came across this study (phase 2 basket trial) in the US. Essentially when exhausting, or before, standard of care options, allows patients to trial off label approved drugs using genomics to identify specific targetable variations
muzzatron
in
SHARE Metastatic Breast Cancer
6 months ago
happy Saturday!
I brought home my dog domino following acl surgery and am overwhelmed about his rehab routine. Massage, ice, meds, trips to vet daily for laser therapy, etc. for at least 8 weeks. Has anyone else been through this and have any coping skills to suggest?
I brought home my dog domino following acl surgery and am overwhelmed about his rehab routine. Massage, ice, meds, trips to vet daily for laser therapy, etc. for at least 8 weeks. Has anyone else been through this and have any coping skills to suggest?
CatDogLover
in
Anxiety and Depression Support
6 months ago
red light therapy
hi everyone! I am wondering if anyone has heard of using red and near infrared light therapy.
hi everyone! I am wondering if anyone has heard of using red and near infrared light therapy.
positiveness
in
My MSAA Community
6 months ago
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Capiverstib
Anyone heard of or started this new FDA approved targeted therapy? What is your experience or understanding?
Anyone heard of or started this new FDA approved targeted therapy? What is your experience or understanding?
Yikes123
in
SHARE Metastatic Breast Cancer
6 months ago
Input on Timing of Initial ADT after RP/SRT Failed
After surgery and salvage radiation therapy (SRT) have failed, it appears I'm headed for androgen deprivation therapy. Like many things in the world of prostate cancer, the recommendations as to when to start ADT seem to be all over the place, so I'm seeking any insights folks may have based on your
After surgery and salvage radiation therapy (SRT) have failed, it appears I'm headed for androgen deprivation therapy. Like many things in the world of prostate cancer, the recommendations as to when to start ADT seem to be all over the place, so I'm seeking any insights folks may have based on your
dans_journey
in
Advanced Prostate Cancer
30 days ago
Seeking to connect, share, support and heal this anxiety
Howdy all: I am TS—my nickname, so it's all good. I have experienced depression for 34 years, when I was first diagnosed. About 5 months ago, I was also diagnosed with general anxiety disorder, Since that time, I have experienced a combination of anxiety, fear and deep loneliness. I am currently on
Howdy all: I am TS—my nickname, so it's all good. I have experienced depression for 34 years, when I was first diagnosed. About 5 months ago, I was also diagnosed with general anxiety disorder, Since that time, I have experienced a combination of anxiety, fear and deep loneliness. I am currently on
LittleShik
in
Anxiety and Depression Support
6 months ago
Parkinson's Nurse update
Hi all, thank you for all your previous posts, they were most helpful. Since then we have had a few medical professionals visit. The Parkinsons Nurse is coming to see my father-in-law tomorrow. Is there any questions we need to be asking? The OT and Physio visited yesterday and recommended a new commode
Hi all, thank you for all your previous posts, they were most helpful. Since then we have had a few medical professionals visit. The Parkinsons Nurse is coming to see my father-in-law tomorrow. Is there any questions we need to be asking? The OT and Physio visited yesterday and recommended a new commode
Loveispatient23
in
PSP Association
6 months ago
recurrence after lobectomy
Hello, I am 53 and live in the UK and I stop smoking in my late 20’. I had a lobectomy of my right lower lobe in April 2022 to remove a minimally invasive adenocarcinoma staged pT1 N0, M0, PL0, R0 (found by complete accident on an abdomen CT scan.) I begged for adjuvant therapy after the operation
Hello, I am 53 and live in the UK and I stop smoking in my late 20’. I had a lobectomy of my right lower lobe in April 2022 to remove a minimally invasive adenocarcinoma staged pT1 N0, M0, PL0, R0 (found by complete accident on an abdomen CT scan.) I begged for adjuvant therapy after the operation
Bibicata
in
The Roy Castle Lung Cancer Foundation
6 months ago
Transformation of Richter's Transformation Treatment to combination targeted therapy - tislelizumab +zanubrutinib (ASH 2023)
Richter's Transformation treatments are typically fixed term R-CHOP*, or modifications of that chemoimmunity therapy. So it's encouraging to hear that [i]"In a phase 2 trial, anti-PD-1 inibitor tislelizumab + next gen BTK inhibitor zanubrutinib had an overall response rate of 58.3% in patients with Richter's
Richter's Transformation treatments are typically fixed term R-CHOP*, or modifications of that chemoimmunity therapy. So it's encouraging to hear that [i]"In a phase 2 trial, anti-PD-1 inibitor tislelizumab + next gen BTK inhibitor zanubrutinib had an overall response rate of 58.3% in patients with Richter's
AussieNeil
Partner
in
CLL Support
6 months ago
Pain everywhere.
I've been 10+ yrs searching for answers. I had some bladder problems in 2013. Doctors did surgery. I almost died. Apparently they told me my blood vessels looked funny. They didn't know if they "knicked " me or what but I lost 8 pints of blood very quickly. They barely got me transfusion in time. I chalked
I've been 10+ yrs searching for answers. I had some bladder problems in 2013. Doctors did surgery. I almost died. Apparently they told me my blood vessels looked funny. They didn't know if they "knicked " me or what but I lost 8 pints of blood very quickly. They barely got me transfusion in time. I chalked
CountryGirl9636
in
Partners for Behcet's
6 months ago
How you can help make ibrutinib plus venetoclax fixed duration therapy a reality for Australians with previously untreated CLL
In Australia, no new medicine can be listed on the Pharmaceutical Benefits Scheme (PBS) unless it has first been recommended by the Pharmaceutical Benefits Advisory Committee (PBAC). In March 2024, PBAC will again consider a submission to recommend a 15-month combination therapy of ibrutinib plus venetoclax
In Australia, no new medicine can be listed on the Pharmaceutical Benefits Scheme (PBS) unless it has first been recommended by the Pharmaceutical Benefits Advisory Committee (PBAC). In March 2024, PBAC will again consider a submission to recommend a 15-month combination therapy of ibrutinib plus venetoclax
CLLerinOz
Administrator
in
CLL Support
6 months ago
Questionn
Can a Patent Ductus Aerteriosus be diagnosed with a posterlateral thoracotomy then be monitor to make sure it closes?
Can a Patent Ductus Aerteriosus be diagnosed with a posterlateral thoracotomy then be monitor to make sure it closes?
LonerIQ
in
Lung Conditions Community Forum
10 months ago
I don't want to live anymore
I've been depressed most of my life. I grew up with 10 brothers and sisters, I got teased constantly because I wasn't as beautiful as my 5 sisters. I would come home from school and hide away in my little 3rd floor bedroom to avoid teasing. I was never close to my mom, in fact I never remember having
I've been depressed most of my life. I grew up with 10 brothers and sisters, I got teased constantly because I wasn't as beautiful as my 5 sisters. I would come home from school and hide away in my little 3rd floor bedroom to avoid teasing. I was never close to my mom, in fact I never remember having
Mynameisreen
in
Major Depressive Disorder (MDD) Support
3 days ago
FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks
From MedPage Today, by Charles Bankhead, Senior Editor, MedPage Today November 28, 2023, Last Updated November 29, 2023. Posted FYI without comment: [i]
FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks, agency
From MedPage Today, by Charles Bankhead, Senior Editor, MedPage Today November 28, 2023, Last Updated November 29, 2023. Posted FYI without comment: [i]
FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy - Applies to all approved therapies, but benefits still outweigh risks, agency
cujoe
in
CLL Support
6 months ago
Calcium supplements
Hi everyone, well lets start with I had a triple bypass 2 year ago after I suffered a cardiac arrest at ten thousand feet on a mountain in the French Alps, I am on blood thinner , statin and high blood pressure tablets, ive had a few teeth problems, my teeth seem to be more brittle and a couple have
Hi everyone, well lets start with I had a triple bypass 2 year ago after I suffered a cardiac arrest at ten thousand feet on a mountain in the French Alps, I am on blood thinner , statin and high blood pressure tablets, ive had a few teeth problems, my teeth seem to be more brittle and a couple have
Ron0325
in
British Heart Foundation
7 days ago
Discrimination at work, not sure if I need a representative or advocate to help if it goes to tribunal
I asked the manager and member of HR if they had read my
Occupational
Therapy
letter and they said no. It felt like a complete waste of time being referred to occupational health if they weren't going to follow up the outcome.
I asked the manager and member of HR if they had read my
Occupational
Therapy
letter and they said no. It felt like a complete waste of time being referred to occupational health if they weren't going to follow up the outcome.
Shanni91
in
Autism Support
1 year ago
Genetic therapy: for solid malignancy hopefully soon
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
ok, I post them also because they are fellow Italians! But the platform is very promising even if clinical use has been approved only for glioma and glioblastoma at the moment. But there are clinical trials going on for solid tumors, prostate included. https://www.genenta.com/wp-content/uploads/2021
Maxone73
in
Advanced Prostate Cancer
6 months ago
it’s time again…
I have been in this depression episode now again for three days, nothing gives me happiness, nothing gives me hope, I see others around me that are having the best life and although I am genuinely happy for them, it digs my hole a little bit deeper, I know from being here many times, it will pass… The
I have been in this depression episode now again for three days, nothing gives me happiness, nothing gives me hope, I see others around me that are having the best life and although I am genuinely happy for them, it digs my hole a little bit deeper, I know from being here many times, it will pass… The
Starr88
in
Major Depressive Disorder (MDD) Support
15 days ago
Getting our Smile Back
This inspires hope: Hyperbaric Oxygen Therapy (HBOT) https://youtu.be/xF4juQrQRn4
This inspires hope: Hyperbaric Oxygen Therapy (HBOT) https://youtu.be/xF4juQrQRn4
Dabaa
in
Cure Parkinson's
16 days ago
The Immune Mind by Monty Lyman - Radio 4
I'm still working on getting a proper understanding of what this Book of the Week is all about. I keep setting it going, and drifting off to sleep. However, today I was awake enough to listen (with quite a good level of attention) to episode 4, which starts off talking about rheumatoid arthritis and
I'm still working on getting a proper understanding of what this Book of the Week is all about. I keep setting it going, and drifting off to sleep. However, today I was awake enough to listen (with quite a good level of attention) to episode 4, which starts off talking about rheumatoid arthritis and
Hezekiah
in
NRAS
17 days ago
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