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Early results of the Pirtobrutinib, Obinituzumab, Venetoclax trial I'm on have just been published
I had a brief
neutropenia
. We stopped treatment briefly during cycle 11 in December, 2023 due to an unknown infection with fever > 100.4F/38C. Per the trial protocol, I was admitted to my local hospital, and did IV antibiotics and IVIG.
I had a brief
neutropenia
. We stopped treatment briefly during cycle 11 in December, 2023 due to an unknown infection with fever > 100.4F/38C. Per the trial protocol, I was admitted to my local hospital, and did IV antibiotics and IVIG.
SeymourB
in
CLL Support
16 days ago
neutropenia back again
My husband encountered Neurtropenia right before his last O infusion. Protocol was one week off venetoclax, blood test, no improvement, GCIF injections which brought his levels up to normal. His Venetoclax dosage was cut from 4 to 3 pills daily. Now, embarking on cycle 10, we are in the “what’s next
My husband encountered Neurtropenia right before his last O infusion. Protocol was one week off venetoclax, blood test, no improvement, GCIF injections which brought his levels up to normal. His Venetoclax dosage was cut from 4 to 3 pills daily. Now, embarking on cycle 10, we are in the “what’s next
lisakc1
in
CLL Support
1 year ago
why neutropenia?
anyone she’d light on why the Vclax is wiping out healthy neutrophils and T cells? It’s happening to me and has caused me to have some nasty infections. Thanks for any medical context.
anyone she’d light on why the Vclax is wiping out healthy neutrophils and T cells? It’s happening to me and has caused me to have some nasty infections. Thanks for any medical context.
Lawand1
in
CLL Support
1 year ago
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looking for next steps for my young husband
Neutropenia
required Neulasta injection.
Jun-Jul 22'-
space oar procedure (necessary as Brad has Ulcerative Colitis)and 26 rounds of radiation to the prostate & pelvic area.
Neutropenia
required Neulasta injection.
Jun-Jul 22'-
space oar procedure (necessary as Brad has Ulcerative Colitis)and 26 rounds of radiation to the prostate & pelvic area.
shaunaliz15
in
Advanced Prostate Cancer
2 months ago
Vertigo and Venclexta?
My husband is starting cycle 12 of Venclexta, reduced to 200mg /day due to 2 bouts of
Neutropenia
, and has recently experienced Vertigo twice. The first time, I did not associate this with the treatment; however, it seemed peculiar when it happened a second time, only eight weeks later.
My husband is starting cycle 12 of Venclexta, reduced to 200mg /day due to 2 bouts of
Neutropenia
, and has recently experienced Vertigo twice. The first time, I did not associate this with the treatment; however, it seemed peculiar when it happened a second time, only eight weeks later.
lisakc1
in
CLL Support
10 months ago
MO recommends decreased Docetaxel dose
His first session did land him in the hospital with possible injection and
neutropenia
. Just wondering if this is common with Docetaxel? Does the 75% dose mean that chemo won’t be as effective? Thank you
His first session did land him in the hospital with possible injection and
neutropenia
. Just wondering if this is common with Docetaxel? Does the 75% dose mean that chemo won’t be as effective? Thank you
Jdhanoa
in
Advanced Prostate Cancer
1 year ago
Reduced-Dose Schedule of Cabazitaxel Viable for Seniors With mCRPC - MedPage Today, November 1, 2023
* * * [i]
Reduced-Dose Schedule of Cabazitaxel Viable for Seniors With mCRPC - Grade 3 or higher
, neutropenic complications reduced by 12-fold, by Mike Bassett, Staff Writer, MedPage Today November 1, 2023.
* * * [i]
Reduced-Dose Schedule of Cabazitaxel Viable for Seniors With mCRPC - Grade 3 or higher
, neutropenic complications reduced by 12-fold, by Mike Bassett, Staff Writer, MedPage Today November 1, 2023.
CaptnMojoe
in
Fight Prostate Cancer
7 months ago
Update treatment
[/i] [i]They told me this last thursday, and also that they wait, starting the third time, because i had
neutropenia
.[/i] [i]Is this known to you, and what should i expext??[/i] [i]Thankss, René [/i]
[/i] [i]They told me this last thursday, and also that they wait, starting the third time, because i had
neutropenia
.[/i] [i]Is this known to you, and what should i expext??[/i] [i]Thankss, René [/i]
Renefaassen
in
CLL Support
10 months ago
Venclexta mono therapy vs Venclexta plus gazyva
His reasoning is that since I have a tendency to
neutropenia
Gazyva would not be well tolerated. Also he explains that the hematological side effects would last a long time after Gazyva treatment is stopped. The other Dr at UCI recommends venetoclax and Gazyva per the trial plan.
His reasoning is that since I have a tendency to
neutropenia
Gazyva would not be well tolerated. Also he explains that the hematological side effects would last a long time after Gazyva treatment is stopped. The other Dr at UCI recommends venetoclax and Gazyva per the trial plan.
ralphfelo
in
CLL Support
10 months ago
V + O for R/R CLL post FCR
[/u] I had 3 rounds of FCR in 2018 stopped because of profound
neutropenia
. I relapsed exactly 2 years later and though I did not start Tx until the 5 year point in 2023, would have gladly started it 9 months ealier due to B symptoms.
[/u] I had 3 rounds of FCR in 2018 stopped because of profound
neutropenia
. I relapsed exactly 2 years later and though I did not start Tx until the 5 year point in 2023, would have gladly started it 9 months ealier due to B symptoms.
skipro
in
CLL Support
7 days ago
CLL replication rate
With treatment, CLL cells are drastically reduced -- a good thing -- but to a lesser extent, so are good cells, hence
neutropenia
. Along with the loss of good cells, so is the natural check on the CLL cells.
With treatment, CLL cells are drastically reduced -- a good thing -- but to a lesser extent, so are good cells, hence
neutropenia
. Along with the loss of good cells, so is the natural check on the CLL cells.
PulsedTherapy
in
CLL Support
2 days ago
#AskChatGPT - Top ADC Treatment for prostate cancer
Significant toxicities included
neutropenia
, but the drug displayed substantial clinical activity (https://www.onclive.com/view/adcs-novel-targets-represent-next-wave-of-treatment-advances-in-mcrpc).
Significant toxicities included
neutropenia
, but the drug displayed substantial clinical activity (https://www.onclive.com/view/adcs-novel-targets-represent-next-wave-of-treatment-advances-in-mcrpc).
God_Loves_Me
in
Advanced Prostate Cancer
18 days ago
Teeth!
Could it be the
neutropenia
, antibacterial mouthwash, something else ... ? Any thoughts or experience?
Could it be the
neutropenia
, antibacterial mouthwash, something else ... ? Any thoughts or experience?
Greenbunnies
in
CLL Support
1 year ago
Neutropenic fever landed me in the hospital after 1st Taxotere infusion
My MO has switched me over to Jevtana, but the likelihood of
Neutropenia
is statistically higher with it vs. Taxotere- ugh.
My MO has switched me over to Jevtana, but the likelihood of
Neutropenia
is statistically higher with it vs. Taxotere- ugh.
V10fanatic
in
Advanced Prostate Cancer
6 months ago
Ibrance v. Kisqali
I took Ibrance for a year and really struggled with terrible brain fog to the extent that I could hardly work, joint pain was awful, had some hair loss, and the usual
neutropenia
and blood work irregularities.
I took Ibrance for a year and really struggled with terrible brain fog to the extent that I could hardly work, joint pain was awful, had some hair loss, and the usual
neutropenia
and blood work irregularities.
Fiercelypink
in
SHARE Metastatic Breast Cancer
10 months ago
Why white blood counts can be high or low. Could a high count be blood cancer, in particular Chronic Lymphocytic Leukemia (CLL)?
[/i]
Low Neutrophils "
" [i]Having a low level of neutrophils (
neutropenia
) does not cause symptoms on its own. However, some of the common causes of
neutropenia
, such as bacterial and viral infections, can cause illness, including fever, sore throat, and fatigue.
[/i]
Low Neutrophils "
" [i]Having a low level of neutrophils (
neutropenia
) does not cause symptoms on its own. However, some of the common causes of
neutropenia
, such as bacterial and viral infections, can cause illness, including fever, sore throat, and fatigue.
AussieNeil
Partner
in
CLL Support
1 year ago
Anyone have a dramatic drop in WBC bordering on neutropenia from pelvic radiation (not chemo)?
Husband is 3/4 of the way through an escalated course of IMRT Prostate bed only radiation (plan was for 33 days but they gave larger doses per day and are trying to do it in 20 days). Today (Saturday) we ended up going to the ER because he was having some strange symptoms. Labs showed his WBC counts
Husband is 3/4 of the way through an escalated course of IMRT Prostate bed only radiation (plan was for 33 days but they gave larger doses per day and are trying to do it in 20 days). Today (Saturday) we ended up going to the ER because he was having some strange symptoms. Labs showed his WBC counts
StephH72
in
Advanced Prostate Cancer
10 months ago
Pancoast Tumor
Began Chemo Radiation the next week ;6 weeks radiation and 4 weeks of chemo with two episodes of
neutropenia
but finally made it through with severe side effects. Good news the initial pain he began Tx with was gone by 3rd day of treatment . A couple injections Neulasta got him through to the end .
Began Chemo Radiation the next week ;6 weeks radiation and 4 weeks of chemo with two episodes of
neutropenia
but finally made it through with severe side effects. Good news the initial pain he began Tx with was gone by 3rd day of treatment . A couple injections Neulasta got him through to the end .
LoveyDearheart
in
Lung Cancer Support
1 year ago
Docetaxel induced febrile neutropenia
Following 1st cycle of Docetaxel on 16th Jan 2023, I had an episode of febrile
neutropenia
(Neutrophil count: 0.07 X 10^9/L) on 25Jan 2023 needing hospital admission and IV antibiotics. I was poorly for 24 hours. Oral ulcers which I had are said to be almost diagnostic of
neutropenia
.
Following 1st cycle of Docetaxel on 16th Jan 2023, I had an episode of febrile
neutropenia
(Neutrophil count: 0.07 X 10^9/L) on 25Jan 2023 needing hospital admission and IV antibiotics. I was poorly for 24 hours. Oral ulcers which I had are said to be almost diagnostic of
neutropenia
.
Jay-kud8
in
Advanced Prostate Cancer
1 year ago
What types of food to eat with Nubeqa, to help protect the liver or other organs?
Is it advisable to eat certain types of food with the Nubeqa, in order to reduce the chances of liver damage and/or blood cell problems like
Neutropenia
? If someone takes a couple tbsp of EVOO before drinking alcohol, it decreases liver toxicity and intoxication/drunkiness.
Is it advisable to eat certain types of food with the Nubeqa, in order to reduce the chances of liver damage and/or blood cell problems like
Neutropenia
? If someone takes a couple tbsp of EVOO before drinking alcohol, it decreases liver toxicity and intoxication/drunkiness.
GeorgeGlass
in
Advanced Prostate Cancer
1 year ago
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