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SGLT-2 Inhibitors to (partially) “Starve” Glucose Dependent Cancers
There has been many theories proposed about how to “starve cancer”. And many have gone down rabbit holes chasing unproven theories about how to do so. Unfortunately, IMO, they simply do not work. Cancers are very metabolically flexible. They will take what they need to survive and grow and adapt to whatever
There has been many theories proposed about how to “starve cancer”. And many have gone down rabbit holes chasing unproven theories about how to do so. Unfortunately, IMO, they simply do not work. Cancers are very metabolically flexible. They will take what they need to survive and grow and adapt to whatever
MateoBeach
in
Fight Prostate Cancer
9 months ago
Anyone turn down a stem cell transplant?
I have post ET MF. Currently I'm on Rux and getting monthly cycles of 5 aza. I don't need transfusions. Day to day I feel pretty good and can do most of what I want. The SCT was recommended because of the risk of progression to AML. I'm finding the decision making to get the SCT very difficult. My
I have post ET MF. Currently I'm on Rux and getting monthly cycles of 5 aza. I don't need transfusions. Day to day I feel pretty good and can do most of what I want. The SCT was recommended because of the risk of progression to AML. I'm finding the decision making to get the SCT very difficult. My
LongETinUS
in
MPN Voice
29 days ago
Krebs Cycle
Has anyone’s heard of the Krebs Cycle, also known as the Citric Acid Cycle? It’s a series of biochemical reactions that happen in the mitochondria and is critical for the formation of energy. Krebs has a book called “The Principles and Applications of Ozone Therapy”. The cycle converts NADH to NAD
Has anyone’s heard of the Krebs Cycle, also known as the Citric Acid Cycle? It’s a series of biochemical reactions that happen in the mitochondria and is critical for the formation of energy. Krebs has a book called “The Principles and Applications of Ozone Therapy”. The cycle converts NADH to NAD
LagLag37
in
Cure Parkinson's
7 months ago
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Giant ovarian cyst- very worried
Hi Everyone , Its my first time posting here but I read some posts and it seems like a very supportive community . I am 42 and not menopausal. I ended up in hospital due to severe pain in my right ovary . After scan I was told this was as due to a raptured cyst in my ovary and nothing to worry
Hi Everyone , Its my first time posting here but I read some posts and it seems like a very supportive community . I am 42 and not menopausal. I ended up in hospital due to severe pain in my right ovary . After scan I was told this was as due to a raptured cyst in my ovary and nothing to worry
martiksa
in
My Ovacome
9 months ago
Scared
Have stage 4 breast cancer which has spread to both lungs and have mental health problems as well.. Question is worried that Maybe having a psychoctic episode with all the stress
Have stage 4 breast cancer which has spread to both lungs and have mental health problems as well.. Question is worried that Maybe having a psychoctic episode with all the stress
Iamhealthy123
in
Lung Conditions Community Forum
9 months ago
Colonoscopy
I had a very stressful colonoscopy last Thursday. Stressful in itself but rendered more so by the Practice Nurse who fasttracked me, saying, ‘Good luck, I hope I’m wrong.’ I defy anyone to not think the worst after that! Anyway, the scope was clear of cancer, or polyps but confirmed what I already knew
I had a very stressful colonoscopy last Thursday. Stressful in itself but rendered more so by the Practice Nurse who fasttracked me, saying, ‘Good luck, I hope I’m wrong.’ I defy anyone to not think the worst after that! Anyway, the scope was clear of cancer, or polyps but confirmed what I already knew
Calceolaria
in
Thyroid UK
7 months ago
Bowel inflammation - any link to PMR/GCA?
I have had problems with diarrhoea for several years now. I have had bad reactions in the past to sertraline (antidepressant) and amoxillin, with constant diarrhoea for several months. However my calprotectin levels (measuring gut inflammation) were normal. Since diagnosis I have been getting frequent
I have had problems with diarrhoea for several years now. I have had bad reactions in the past to sertraline (antidepressant) and amoxillin, with constant diarrhoea for several months. However my calprotectin levels (measuring gut inflammation) were normal. Since diagnosis I have been getting frequent
Broseley
in
PMRGCAuk
7 months ago
On another subject …
Inspired bya post on another site I’d like to ask if anyone has high risk mutations and has NOT had a stem cell transplant and has NOT progressed to leukaemia? On the other site there were a few who had had MF for quite few years but with treatment were doing ok, and weren’t having transplants, for
Inspired bya post on another site I’d like to ask if anyone has high risk mutations and has NOT had a stem cell transplant and has NOT progressed to leukaemia? On the other site there were a few who had had MF for quite few years but with treatment were doing ok, and weren’t having transplants, for
lizzziep
in
MPN Voice
1 month ago
small cell pc options?
my father has been treating this for 5 years. New biopsy revealed small cell pc which was also in the initial biopsy. The rechallenge of carboplatin and etoposide doesn’t seem to be working. They have suggested immunotherapy ( not sure what type). Thoughts? Also any research out there regarding PRRT?
my father has been treating this for 5 years. New biopsy revealed small cell pc which was also in the initial biopsy. The rechallenge of carboplatin and etoposide doesn’t seem to be working. They have suggested immunotherapy ( not sure what type). Thoughts? Also any research out there regarding PRRT?
Poppi07
in
Advanced Prostate Cancer
9 months ago
still no answers
I wrote in a week or so ago about rib pain and protruding left rib cage. Since then I've been to see a private rhematologist, then the practice nurse at my local NH surgery, and lastly took myself to A&E locally on Sunday. The rolling spasm I feel on and off just under the left ribs is the upper
I wrote in a week or so ago about rib pain and protruding left rib cage. Since then I've been to see a private rhematologist, then the practice nurse at my local NH surgery, and lastly took myself to A&E locally on Sunday. The rolling spasm I feel on and off just under the left ribs is the upper
Bennijax
in
PMRGCAuk
11 months ago
crohns scare
I had a colonoscopy 6 months ago . All was clear , no cancer no ibd. Since I’ve had in and off abdominal pain and inflammation . I just been diagnosed with a parasite of the intestine as well. I have. Signoidoscopy tomorrow, could I still have Crohn’s despite nothing was found 6 months ago? Or could
I had a colonoscopy 6 months ago . All was clear , no cancer no ibd. Since I’ve had in and off abdominal pain and inflammation . I just been diagnosed with a parasite of the intestine as well. I have. Signoidoscopy tomorrow, could I still have Crohn’s despite nothing was found 6 months ago? Or could
jennwhite80
in
Colon Cancer Connected
7 months ago
ultrasound result
Hello, me again! So my partner has had his letter telling his ultrasound result. It says that there is 24mm irregular area withing the left lobe of his liver. It also says that this could be nothing more than focal fat or a cancer. He now is going to have an urgent MRI. I am so scared now. After
Hello, me again! So my partner has had his letter telling his ultrasound result. It says that there is 24mm irregular area withing the left lobe of his liver. It also says that this could be nothing more than focal fat or a cancer. He now is going to have an urgent MRI. I am so scared now. After
pussycat66
in
British Liver Trust
9 months ago
Thank you
I am overwhelmed with gratitude to all those that have responded to my post yesterday . I responded individually to the first people ( I’m not sure how to private message , I’m a bit crap with technology and my texting thumb is numb 🤦🏻♀️) But thank you all . I have had both psychology sessions
I am overwhelmed with gratitude to all those that have responded to my post yesterday . I responded individually to the first people ( I’m not sure how to private message , I’m a bit crap with technology and my texting thumb is numb 🤦🏻♀️) But thank you all . I have had both psychology sessions
PWT1
in
My Ovacome
1 month ago
I'm Back....
Hi Everyone, I was on this site several months ago and since then have been in a psychiatric hospital, been seeing a psychiatrist, had EMDR and ketamine treatments, had weekly therapy sessions and am about to try a new therapist, and have tried five different anti-depressants. I'm still struggling
Hi Everyone, I was on this site several months ago and since then have been in a psychiatric hospital, been seeing a psychiatrist, had EMDR and ketamine treatments, had weekly therapy sessions and am about to try a new therapist, and have tried five different anti-depressants. I'm still struggling
Woolybluecurl
in
Anxiety and Depression Support
1 month ago
Scared I may have ovarian cancer
Ca125 an platelets raised. Severe abdominal pain an bloating scared I may have ovarian cancer awaiting an urgent specialist appointment 😢 is there anyone out there who is waiting to be seen like me? How do you not think the worst I'm making myself ill with worry
Ca125 an platelets raised. Severe abdominal pain an bloating scared I may have ovarian cancer awaiting an urgent specialist appointment 😢 is there anyone out there who is waiting to be seen like me? How do you not think the worst I'm making myself ill with worry
MK82
in
My Ovacome
9 months ago
anxiety depression
hi everyone I am struggling with chronic anxiety attacks and mild depression. Anxiety to a point where I’m scared of being left alone at home
hi everyone I am struggling with chronic anxiety attacks and mild depression. Anxiety to a point where I’m scared of being left alone at home
Niecy89
in
Anxiety and Depression Support
5 months ago
Touchpoint Solutions for ADHD/Focus
My 8 yo daughter was diagnosed with ADHD last year. After a several month wait due to insurance and availability limitations, she is now in therapy and I think it will be very helpful for her. She continues to struggle in school. I hoping to avoid medication if I can, but I also know it will be some
My 8 yo daughter was diagnosed with ADHD last year. After a several month wait due to insurance and availability limitations, she is now in therapy and I think it will be very helpful for her. She continues to struggle in school. I hoping to avoid medication if I can, but I also know it will be some
Otter1313
in
CHADD's ADHD Parents Together
1 month ago
Have you taken LUMAKRAS (sotorasib)? If so, you might be interested ... read more below
The U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) will review data supporting the supplemental New Drug Application (sNDA) for the full approval of LUMAKRAS® (sotorasib) for adults with previously treated locally advanced or metastatic KRAS G12C-mutated non-small cell
The U.S. Food and Drug Administration (FDA) Oncologic Drugs Advisory Committee (ODAC) will review data supporting the supplemental New Drug Application (sNDA) for the full approval of LUMAKRAS® (sotorasib) for adults with previously treated locally advanced or metastatic KRAS G12C-mutated non-small cell
Miranda_GO2
Partner
in
Lung Cancer Support
9 months ago
klonopin vs Xanax
hey y’all! So I’m on my 6th go of trying new meds for my panic disorder. Tried a lot of things in the past and right now my Dr is thinking of adding either klonopin or xanax to my twice daily buspirone, but I told her I wanted to ask around first. I know everyone experiences things differently but I’
hey y’all! So I’m on my 6th go of trying new meds for my panic disorder. Tried a lot of things in the past and right now my Dr is thinking of adding either klonopin or xanax to my twice daily buspirone, but I told her I wanted to ask around first. I know everyone experiences things differently but I’
Siobhanny
in
Anxiety and Depression Support
5 months ago
Dark Green stool
I am 23 years old, I have dark green stool problem as well as left side middle abdomen pain. I am feeling very discomfort on left side middle abdomen pain after passing stool and sometimes after eating food. I am done ultrasound but report is normal I also experience sometimes diarrhea and constipation
I am 23 years old, I have dark green stool problem as well as left side middle abdomen pain. I am feeling very discomfort on left side middle abdomen pain after passing stool and sometimes after eating food. I am done ultrasound but report is normal I also experience sometimes diarrhea and constipation
Sohankumar34561
in
Pain Concern
7 months ago
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